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Volumn 46, Issue , 2015, Pages 221-231

Role of adaptor protein MyD88 in TLR-mediated preconditioning and neuroprotection after acute excitotoxicity

Author keywords

Excitotoxicity; Microglia; MyD88; Neuroprotection; Preconditioning; Toll like receptors

Indexed keywords

KAINIC ACID; LIPOPOLYSACCHARIDE; MESSENGER RNA; MYELOID DIFFERENTIATION FACTOR 88; POLYINOSINIC POLYCYTIDYLIC ACID; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; LIPOPEPTIDE; PAM(3)CSK(4) PEPTIDE;

EID: 84928825761     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2015.02.019     Document Type: Article
Times cited : (30)

References (63)
  • 1
    • 84897354350 scopus 로고    scopus 로고
    • Patrolling monocytes play a critical role in CX3CR1-mediated neuroprotection during excitotoxicity
    • Bellavance M.-A., Gosselin D., Yong V.W., Stys P.K., Rivest S. Patrolling monocytes play a critical role in CX3CR1-mediated neuroprotection during excitotoxicity. Brain Struct. Funct. 2014, 10.1007/s00429-014-0759-z.
    • (2014) Brain Struct. Funct.
    • Bellavance, M.-A.1    Gosselin, D.2    Yong, V.W.3    Stys, P.K.4    Rivest, S.5
  • 2
    • 22544483518 scopus 로고    scopus 로고
    • Modulator effects of interleukin-1beta and tumor necrosis factor-alpha on AMPA-induced excitotoxicity in mouse organotypic hippocampal slice cultures
    • Bernardino L., Xapelli S., Silva A.P., Jakobsen B., Poulsen F.R., Oliveira C.R., Vezzani A., Malva J.O., Zimmer J. Modulator effects of interleukin-1beta and tumor necrosis factor-alpha on AMPA-induced excitotoxicity in mouse organotypic hippocampal slice cultures. J. Neurosci. 2005, 25:6734-6744. 10.1523/JNEUROSCI.1510-05.2005.
    • (2005) J. Neurosci. , vol.25 , pp. 6734-6744
    • Bernardino, L.1    Xapelli, S.2    Silva, A.P.3    Jakobsen, B.4    Poulsen, F.R.5    Oliveira, C.R.6    Vezzani, A.7    Malva, J.O.8    Zimmer, J.9
  • 3
    • 2442685455 scopus 로고    scopus 로고
    • Effects of TNF-alpha and IFN-gamma on nitric oxide-induced neurotoxicity in the mouse brain
    • Blais V., Rivest S. Effects of TNF-alpha and IFN-gamma on nitric oxide-induced neurotoxicity in the mouse brain. J. Immunol. 2004, 172:7043-7052.
    • (2004) J. Immunol. , vol.172 , pp. 7043-7052
    • Blais, V.1    Rivest, S.2
  • 4
    • 33845768784 scopus 로고    scopus 로고
    • Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
    • Block M.L., Zecca L., Hong J.-S. Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nat. Rev. Neurosci. 2007, 8:57-69. 10.1038/nrn2038.
    • (2007) Nat. Rev. Neurosci. , vol.8 , pp. 57-69
    • Block, M.L.1    Zecca, L.2    Hong, J.-S.3
  • 6
    • 36248934262 scopus 로고    scopus 로고
    • Toll-like receptor signaling is critical for Wallerian degeneration and functional recovery after peripheral nerve injury
    • Boivin A., Pineau I., Barrette B., Filali M., Vallières N., Rivest S., Lacroix S. Toll-like receptor signaling is critical for Wallerian degeneration and functional recovery after peripheral nerve injury. J. Neurosci. 2007, 27:12565-12576. 10.1523/JNEUROSCI.3027-07.2007.
    • (2007) J. Neurosci. , vol.27 , pp. 12565-12576
    • Boivin, A.1    Pineau, I.2    Barrette, B.3    Filali, M.4    Vallières, N.5    Rivest, S.6    Lacroix, S.7
  • 7
    • 0026738695 scopus 로고
    • Activated microglia mediate neuronal cell injury via a nitric oxide mechanism
    • Chao C.C., Hu S., Molitor T.W., Shaskan E.G., Peterson P.K. Activated microglia mediate neuronal cell injury via a nitric oxide mechanism. J. Immunol. 1992, 149:2736-2741.
    • (1992) J. Immunol. , vol.149 , pp. 2736-2741
    • Chao, C.C.1    Hu, S.2    Molitor, T.W.3    Shaskan, E.G.4    Peterson, P.K.5
  • 8
    • 84865238053 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced microglial activation and neuroprotection against experimental brain injury is independent of hematogenous TLR4
    • Chen Z., Jalabi W., Shpargel K.B., Farabaugh K.T., Dutta R., Yin X., Kidd G.J., Bergmann C.C., Stohlman S.A., Trapp B.D. Lipopolysaccharide-induced microglial activation and neuroprotection against experimental brain injury is independent of hematogenous TLR4. J. Neurosci. 2012, 32:11706-11715. 10.1523/JNEUROSCI.0730-12.2012.
    • (2012) J. Neurosci. , vol.32 , pp. 11706-11715
    • Chen, Z.1    Jalabi, W.2    Shpargel, K.B.3    Farabaugh, K.T.4    Dutta, R.5    Yin, X.6    Kidd, G.J.7    Bergmann, C.C.8    Stohlman, S.A.9    Trapp, B.D.10
  • 9
    • 0028178798 scopus 로고
    • Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis
    • Cheng B., Christakos S., Mattson M.P. Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis. Neuron 1994, 12:139-153.
    • (1994) Neuron , vol.12 , pp. 139-153
    • Cheng, B.1    Christakos, S.2    Mattson, M.P.3
  • 11
    • 33947621993 scopus 로고    scopus 로고
    • Assessing nest building in mice
    • Deacon R.M.J. Assessing nest building in mice. Nat. Protoc. 2006, 1:1117-1119. 10.1038/nprot.2006.170.
    • (2006) Nat. Protoc. , vol.1 , pp. 1117-1119
    • Deacon, R.M.J.1
  • 12
    • 76849083197 scopus 로고    scopus 로고
    • Behavioural and histological effects of preconditioning with lipopolysaccharide in epileptic rats
    • Dmowska M., Cybulska R., Schoenborn R., Piersiak T., Jaworska-Adamu J., Gawron A. Behavioural and histological effects of preconditioning with lipopolysaccharide in epileptic rats. Neurochem. Res. 2010, 35:262-272. 10.1007/s11064-009-0050-5.
    • (2010) Neurochem. Res. , vol.35 , pp. 262-272
    • Dmowska, M.1    Cybulska, R.2    Schoenborn, R.3    Piersiak, T.4    Jaworska-Adamu, J.5    Gawron, A.6
  • 14
    • 84863868058 scopus 로고    scopus 로고
    • MyD88 deficiency results in both cognitive and motor impairments in mice
    • Drouin-Ouellet J., LeBel M., Filali M., Cicchetti F. MyD88 deficiency results in both cognitive and motor impairments in mice. Brain Behav. Immun. 2012, 26:880-885. 10.1016/j.bbi.2012.02.007.
    • (2012) Brain Behav. Immun. , vol.26 , pp. 880-885
    • Drouin-Ouellet, J.1    LeBel, M.2    Filali, M.3    Cicchetti, F.4
  • 15
    • 79954802122 scopus 로고    scopus 로고
    • Disruption of downstream MyD88 or TRIF Toll-like receptor signaling does not protect against cerebral ischemia
    • Famakin B.M., Mou Y., Ruetzler C.A., Bembry J., Maric D., Hallenbeck J.M. Disruption of downstream MyD88 or TRIF Toll-like receptor signaling does not protect against cerebral ischemia. Brain Res. 2011, 1388:148-156. 10.1016/j.brainres.2011.02.074.
    • (2011) Brain Res. , vol.1388 , pp. 148-156
    • Famakin, B.M.1    Mou, Y.2    Ruetzler, C.A.3    Bembry, J.4    Maric, D.5    Hallenbeck, J.M.6
  • 16
    • 61949343401 scopus 로고    scopus 로고
    • Pro-inflammatory cytokine TNF-alpha as a neuroprotective agent in the brain
    • Figiel I. Pro-inflammatory cytokine TNF-alpha as a neuroprotective agent in the brain. Acta Neurobiol. Exp. (Wars) 2008, 68:526-534.
    • (2008) Acta Neurobiol. Exp. (Wars) , vol.68 , pp. 526-534
    • Figiel, I.1
  • 17
    • 0028959038 scopus 로고
    • Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats. Statistical validation
    • discussion 635
    • Garcia J.H., Wagner S., Liu K.F., Hu X.J. Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats. Statistical validation. Stroke 1995, 26:627-634. discussion 635.
    • (1995) Stroke , vol.26 , pp. 627-634
    • Garcia, J.H.1    Wagner, S.2    Liu, K.F.3    Hu, X.J.4
  • 18
    • 84883002110 scopus 로고    scopus 로고
    • IL-1RAcPb signaling regulates adaptive mechanisms in neurons that promote their long-term survival following excitotoxic insults
    • Gosselin D., Bellavance M.-A., Rivest S. IL-1RAcPb signaling regulates adaptive mechanisms in neurons that promote their long-term survival following excitotoxic insults. Front. Cell Neurosci. 2013, 7:9. 10.3389/fncel.2013.00009.
    • (2013) Front. Cell Neurosci. , vol.7 , pp. 9
    • Gosselin, D.1    Bellavance, M.-A.2    Rivest, S.3
  • 19
    • 34547456529 scopus 로고    scopus 로고
    • Impairment of microglial responses to facial nerve axotomy in cathepsin S-deficient mice
    • Hao H.P., Doh-Ura K., Nakanishi H. Impairment of microglial responses to facial nerve axotomy in cathepsin S-deficient mice. J. Neurosci. Res. 2007, 85:2196-2206. 10.1002/jnr.21357.
    • (2007) J. Neurosci. Res. , vol.85 , pp. 2196-2206
    • Hao, H.P.1    Doh-Ura, K.2    Nakanishi, H.3
  • 21
    • 35448993875 scopus 로고    scopus 로고
    • Activation of Toll-like receptor 4 signaling contributes to hippocampal neuronal death following global cerebral ischemia/reperfusion
    • Hua F., Ma J., Ha T., Xia Y., Kelley J., Williams D.L., Kao R.L., Browder I.W., Schweitzer J.B., Kalbfleisch J.H., Li C. Activation of Toll-like receptor 4 signaling contributes to hippocampal neuronal death following global cerebral ischemia/reperfusion. J. Neuroimmunol. 2007, 190:101-111. 10.1016/j.jneuroim.2007.08.014.
    • (2007) J. Neuroimmunol. , vol.190 , pp. 101-111
    • Hua, F.1    Ma, J.2    Ha, T.3    Xia, Y.4    Kelley, J.5    Williams, D.L.6    Kao, R.L.7    Browder, I.W.8    Schweitzer, J.B.9    Kalbfleisch, J.H.10    Li, C.11
  • 22
    • 47549085328 scopus 로고    scopus 로고
    • Preconditioning with a TLR2 specific ligand increases resistance to cerebral ischemia/reperfusion injury
    • Hua F., Ma J., Ha T., Kelley J., Williams D.L., Kao R.L., Kalbfleisch J.H., Browder I.W., Li C. Preconditioning with a TLR2 specific ligand increases resistance to cerebral ischemia/reperfusion injury. J. Neuroimmunol. 2008, 199:75-82. 10.1016/j.jneuroim.2008.05.009.
    • (2008) J. Neuroimmunol. , vol.199 , pp. 75-82
    • Hua, F.1    Ma, J.2    Ha, T.3    Kelley, J.4    Williams, D.L.5    Kao, R.L.6    Kalbfleisch, J.H.7    Browder, I.W.8    Li, C.9
  • 23
    • 0034845295 scopus 로고    scopus 로고
    • Enhanced expression of Iba1, ionized calcium-binding adapter molecule 1, after transient focal cerebral ischemia in rat brain
    • Ito D., Tanaka K., Suzuki S., Dembo T., Fukuuchi Y. Enhanced expression of Iba1, ionized calcium-binding adapter molecule 1, after transient focal cerebral ischemia in rat brain. Stroke 2001, 32:1208-1215.
    • (2001) Stroke , vol.32 , pp. 1208-1215
    • Ito, D.1    Tanaka, K.2    Suzuki, S.3    Dembo, T.4    Fukuuchi, Y.5
  • 24
    • 0033166472 scopus 로고    scopus 로고
    • Unresponsiveness of MyD88-deficient mice to endotoxin
    • Kawai T., Adachi O., Ogawa T., Takeda K., Akira S. Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 1999, 11:115-122.
    • (1999) Immunity , vol.11 , pp. 115-122
    • Kawai, T.1    Adachi, O.2    Ogawa, T.3    Takeda, K.4    Akira, S.5
  • 25
    • 34250182782 scopus 로고    scopus 로고
    • Toll-like receptor (TLR)-2 and TLR-4 regulate inflammation, gliosis, and myelin sparing after spinal cord injury
    • Kigerl K.A., Lai W., Rivest S., Hart R.P., Satoskar A.R., Popovich P.G. Toll-like receptor (TLR)-2 and TLR-4 regulate inflammation, gliosis, and myelin sparing after spinal cord injury. J. Neurochem. 2007, 102:37-50. 10.1111/j.1471-4159.2007.04524.x.
    • (2007) J. Neurochem. , vol.102 , pp. 37-50
    • Kigerl, K.A.1    Lai, W.2    Rivest, S.3    Hart, R.P.4    Satoskar, A.R.5    Popovich, P.G.6
  • 26
    • 0033038790 scopus 로고    scopus 로고
    • Effects of systemic immunogenic insults and circulating proinflammatory cytokines on the transcription of the inhibitory factor kappaB alpha within specific cellular populations of the rat brain
    • Laflamme N., Rivest S. Effects of systemic immunogenic insults and circulating proinflammatory cytokines on the transcription of the inhibitory factor kappaB alpha within specific cellular populations of the rat brain. J. Neurochem. 1999, 73:309-321.
    • (1999) J. Neurochem. , vol.73 , pp. 309-321
    • Laflamme, N.1    Rivest, S.2
  • 27
    • 0038744340 scopus 로고    scopus 로고
    • Cooperation between Toll-like receptor 2 and 4 in the brain of mice challenged with cell wall components derived from gram-negative and gram-positive bacteria
    • Laflamme N., Echchannaoui H., Landmann R., Rivest S. Cooperation between Toll-like receptor 2 and 4 in the brain of mice challenged with cell wall components derived from gram-negative and gram-positive bacteria. Eur. J. Immunol. 2003, 33:1127-1138. 10.1002/eji.200323821.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 1127-1138
    • Laflamme, N.1    Echchannaoui, H.2    Landmann, R.3    Rivest, S.4
  • 28
    • 33847785649 scopus 로고    scopus 로고
    • Selective ablation of proliferating microglial cells exacerbates ischemic injury in the brain
    • Lalancette-Hébert M., Gowing G., Simard A., Weng Y.-C., Kriz J. Selective ablation of proliferating microglial cells exacerbates ischemic injury in the brain. J. Neurosci. 2007, 27:2596-2605. 10.1523/JNEUROSCI.5360-06.2007.
    • (2007) J. Neurosci. , vol.27 , pp. 2596-2605
    • Lalancette-Hébert, M.1    Gowing, G.2    Simard, A.3    Weng, Y.-C.4    Kriz, J.5
  • 29
    • 64549132610 scopus 로고    scopus 로고
    • Live imaging of Toll-like receptor 2 response in cerebral ischaemia reveals a role of olfactory bulb microglia as modulators of inflammation
    • Lalancette-Hébert M., Phaneuf D., Soucy G., Weng Y.C., Kriz J. Live imaging of Toll-like receptor 2 response in cerebral ischaemia reveals a role of olfactory bulb microglia as modulators of inflammation. Brain 2009, 132:940-954. 10.1093/brain/awn345.
    • (2009) Brain , vol.132 , pp. 940-954
    • Lalancette-Hébert, M.1    Phaneuf, D.2    Soucy, G.3    Weng, Y.C.4    Kriz, J.5
  • 31
    • 84865498037 scopus 로고    scopus 로고
    • Effects of myeloablation, peripheral chimerism, and whole-body irradiation on the entry of bone marrow-derived cells into the brain
    • Lampron A., Lessard M., Rivest S. Effects of myeloablation, peripheral chimerism, and whole-body irradiation on the entry of bone marrow-derived cells into the brain. Cell Transplant. 2012, 21:1149-1159. 10.3727/096368911X593154.
    • (2012) Cell Transplant. , vol.21 , pp. 1149-1159
    • Lampron, A.1    Lessard, M.2    Rivest, S.3
  • 35
    • 84880447788 scopus 로고    scopus 로고
    • Innate immune regulation by Toll-like receptors in the brain
    • Mallard C. Innate immune regulation by Toll-like receptors in the brain. ISRN Neurol. 2012, 2012:1-19. 10.1016/j.nbd.2011.07.011.
    • (2012) ISRN Neurol. , vol.2012 , pp. 1-19
    • Mallard, C.1
  • 37
    • 59349116736 scopus 로고    scopus 로고
    • Toll-like receptor signaling in endogenous neuroprotection and stroke
    • Marsh B.J., Williams-Karnesky R.L., Stenzel-Poore M.P. Toll-like receptor signaling in endogenous neuroprotection and stroke. Neuroscience 2009, 158:1007-1020. 10.1016/j.neuroscience.2008.07.067.
    • (2009) Neuroscience , vol.158 , pp. 1007-1020
    • Marsh, B.J.1    Williams-Karnesky, R.L.2    Stenzel-Poore, M.P.3
  • 38
    • 0043180531 scopus 로고    scopus 로고
    • Excitotoxic and excitoprotective mechanisms: abundant targets for the prevention and treatment of neurodegenerative disorders
    • Mattson M.P. Excitotoxic and excitoprotective mechanisms: abundant targets for the prevention and treatment of neurodegenerative disorders. Neuromol. Med. 2003, 3:65-94. 10.1385/NMM:3:2:65.
    • (2003) Neuromol. Med. , vol.3 , pp. 65-94
    • Mattson, M.P.1
  • 39
    • 84887611153 scopus 로고    scopus 로고
    • Real-time in vivo imaging reveals the ability of monocytes to clear vascular amyloid beta
    • Michaud J.-P., Bellavance M.-A., Préfontaine P., Rivest S. Real-time in vivo imaging reveals the ability of monocytes to clear vascular amyloid beta. Cell Rep. 2013, 5:646-653. 10.1016/j.celrep.2013.10.010.
    • (2013) Cell Rep. , vol.5 , pp. 646-653
    • Michaud, J.-P.1    Bellavance, M.-A.2    Préfontaine, P.3    Rivest, S.4
  • 41
    • 0034193376 scopus 로고    scopus 로고
    • Role of microglial-derived tumor necrosis factor in mediating CD14 transcription and nuclear factor kappa B activity in the brain during endotoxemia
    • Nadeau S., Rivest S. Role of microglial-derived tumor necrosis factor in mediating CD14 transcription and nuclear factor kappa B activity in the brain during endotoxemia. J. Neurosci. 2000, 20:3456-3468.
    • (2000) J. Neurosci. , vol.20 , pp. 3456-3468
    • Nadeau, S.1    Rivest, S.2
  • 42
    • 60149098421 scopus 로고    scopus 로고
    • Debris clearance by microglia: an essential link between degeneration and regeneration
    • Neumann H., Kotter M.R., Franklin R.J.M. Debris clearance by microglia: an essential link between degeneration and regeneration. Brain 2009, 132:288-295. 10.1093/brain/awn109.
    • (2009) Brain , vol.132 , pp. 288-295
    • Neumann, H.1    Kotter, M.R.2    Franklin, R.J.M.3
  • 43
    • 79955745301 scopus 로고    scopus 로고
    • Toll-like receptor signaling in neural plasticity and disease
    • Okun E., Griffioen K.J., Mattson M.P. Toll-like receptor signaling in neural plasticity and disease. Trends Neurosci. 2011, 34:269-281. 10.1016/j.tins.2011.02.005.
    • (2011) Trends Neurosci. , vol.34 , pp. 269-281
    • Okun, E.1    Griffioen, K.J.2    Mattson, M.P.3
  • 46
    • 84880447854 scopus 로고    scopus 로고
    • Evidence for a gender-specific protective role of innate immune receptors in a model of perinatal brain injury
    • Pimentel-Coelho P.M., Michaud J.-P., Rivest S. Evidence for a gender-specific protective role of innate immune receptors in a model of perinatal brain injury. J. Neurosci. 2013, 33:11556-11572. 10.1523/JNEUROSCI.0535-13.2013.
    • (2013) J. Neurosci. , vol.33 , pp. 11556-11572
    • Pimentel-Coelho, P.M.1    Michaud, J.-P.2    Rivest, S.3
  • 47
    • 66449130960 scopus 로고    scopus 로고
    • Regulation of innate immune responses in the brain
    • Rivest S. Regulation of innate immune responses in the brain. Nat. Rev. Immunol. 2009, 9:429-439. 10.1038/nri2565.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 429-439
    • Rivest, S.1
  • 48
    • 7644232937 scopus 로고    scopus 로고
    • Endotoxin preconditioning prevents cellular inflammatory response during ischemic neuroprotection in mice
    • Rosenzweig H.L., Lessov N.S., Henshall D.C., Minami M., Simon R.P., Stenzel-Poore M.P. Endotoxin preconditioning prevents cellular inflammatory response during ischemic neuroprotection in mice. Stroke 2004, 35:2576-2581. 10.1161/01.STR.0000143450.04438.ae.
    • (2004) Stroke , vol.35 , pp. 2576-2581
    • Rosenzweig, H.L.1    Lessov, N.S.2    Henshall, D.C.3    Minami, M.4    Simon, R.P.5    Stenzel-Poore, M.P.6
  • 49
    • 68149173324 scopus 로고    scopus 로고
    • TNF-preconditioning protects neurons via neuron-specific up-regulation of CREB-binding protein
    • Saha R.N., Ghosh A., Palencia C.A., Fung Y.K., Dudek S.M., Pahan K. TNF-preconditioning protects neurons via neuron-specific up-regulation of CREB-binding protein. J. Immunol. 2009, 183:2068-2078. 10.4049/jimmunol.0801892.
    • (2009) J. Immunol. , vol.183 , pp. 2068-2078
    • Saha, R.N.1    Ghosh, A.2    Palencia, C.A.3    Fung, Y.K.4    Dudek, S.M.5    Pahan, K.6
  • 50
    • 14844309321 scopus 로고    scopus 로고
    • Protective autoimmunity: interferon-gamma enables microglia to remove glutamate without evoking inflammatory mediators
    • Shaked I., Tchoresh D., Gersner R., Meiri G., Mordechai S., Xiao X., Hart R.P., Schwartz M. Protective autoimmunity: interferon-gamma enables microglia to remove glutamate without evoking inflammatory mediators. J. Neurochem. 2005, 92:997-1009. 10.1111/j.1471-4159.2004.02954.x.
    • (2005) J. Neurochem. , vol.92 , pp. 997-1009
    • Shaked, I.1    Tchoresh, D.2    Gersner, R.3    Meiri, G.4    Mordechai, S.5    Xiao, X.6    Hart, R.P.7    Schwartz, M.8
  • 51
    • 37049028157 scopus 로고    scopus 로고
    • Neuroprotective effects of resident microglia following acute brain injury
    • Simard A.R., Rivest S. Neuroprotective effects of resident microglia following acute brain injury. J. Comp. Neurol. 2007, 504:716-729. 10.1002/cne.21469.
    • (2007) J. Comp. Neurol. , vol.504 , pp. 716-729
    • Simard, A.R.1    Rivest, S.2
  • 53
    • 84894582125 scopus 로고    scopus 로고
    • Toll-like receptor 2-mediated alternative activation of microglia is protective after spinal cord injury
    • Stirling D.P., Cummins K., Mishra M., Teo W., Yong V.W., Stys P. Toll-like receptor 2-mediated alternative activation of microglia is protective after spinal cord injury. Brain 2013, 137:707-723. 10.1093/brain/awt341.
    • (2013) Brain , vol.137 , pp. 707-723
    • Stirling, D.P.1    Cummins, K.2    Mishra, M.3    Teo, W.4    Yong, V.W.5    Stys, P.6
  • 54
    • 77950343791 scopus 로고    scopus 로고
    • Pattern recognition receptors and inflammation
    • Takeuchi O., Akira S. Pattern recognition receptors and inflammation. Cell 2010, 140:805-820. 10.1016/j.cell.2010.01.022.
    • (2010) Cell , vol.140 , pp. 805-820
    • Takeuchi, O.1    Akira, S.2
  • 55
    • 0031059654 scopus 로고    scopus 로고
    • Lipopolysaccharide pre-treatment induces resistance against subsequent focal cerebral ischemic damage in spontaneously hypertensive rats
    • Tasaki K., Ruetzler C.A., Ohtsuki T., Martin D., Nawashiro H., Hallenbeck J.M. Lipopolysaccharide pre-treatment induces resistance against subsequent focal cerebral ischemic damage in spontaneously hypertensive rats. Brain Res. 1997, 748:267-270.
    • (1997) Brain Res. , vol.748 , pp. 267-270
    • Tasaki, K.1    Ruetzler, C.A.2    Ohtsuki, T.3    Martin, D.4    Nawashiro, H.5    Hallenbeck, J.M.6
  • 56
    • 30644480429 scopus 로고    scopus 로고
    • Tumor necrosis factor but not interleukin 1 mediates neuroprotection in response to acute nitric oxide excitotoxicity
    • Turrin N.P. Tumor necrosis factor but not interleukin 1 mediates neuroprotection in response to acute nitric oxide excitotoxicity. J. Neurosci. 2006, 26:143-151. 10.1523/JNEUROSCI.4032-05.2006.
    • (2006) J. Neurosci. , vol.26 , pp. 143-151
    • Turrin, N.P.1
  • 58
    • 80053974958 scopus 로고    scopus 로고
    • LPS preconditioning redirects TLR signaling following stroke: TRIF-IRF3 plays a seminal role in mediating tolerance to ischemic injury
    • Vartanian K.B., Stevens S.L., Marsh B.J., Williams-Karnesky R., Lessov N.S., Stenzel-Poore M.P. LPS preconditioning redirects TLR signaling following stroke: TRIF-IRF3 plays a seminal role in mediating tolerance to ischemic injury. J. Neuroinflammation 2011, 8:140. 10.1186/1742-2094-8-140.
    • (2011) J. Neuroinflammation , vol.8 , pp. 140
    • Vartanian, K.B.1    Stevens, S.L.2    Marsh, B.J.3    Williams-Karnesky, R.4    Lessov, N.S.5    Stenzel-Poore, M.P.6
  • 59
    • 20344388665 scopus 로고    scopus 로고
    • Kainic acid-mediated excitotoxicity as a model for neurodegeneration
    • Wang Q., Yu S., Simonyi A., Sun G.Y., Sun A.Y. Kainic acid-mediated excitotoxicity as a model for neurodegeneration. Mol. Neurobiol. 2005, 31:3-16. 10.1385/MN:31:1-3:003.
    • (2005) Mol. Neurobiol. , vol.31 , pp. 3-16
    • Wang, Q.1    Yu, S.2    Simonyi, A.3    Sun, G.Y.4    Sun, A.Y.5
  • 61
    • 50249102689 scopus 로고    scopus 로고
    • Upregulated expression of Toll-like receptor 4 in monocytes correlates with severity of acute cerebral infarction
    • Yang Q.-W., Li J.-C., Lu F.-L., Wen A.-Q., Xiang J., Zhang L.-L., Huang Z.-Y., Wang J.-Z. Upregulated expression of Toll-like receptor 4 in monocytes correlates with severity of acute cerebral infarction. J. Cereb. Blood Flow Metab. 2008, 28:1588-1596. 10.1038/jcbfm.2008.50.
    • (2008) J. Cereb. Blood Flow Metab. , vol.28 , pp. 1588-1596
    • Yang, Q.-W.1    Li, J.-C.2    Lu, F.-L.3    Wen, A.-Q.4    Xiang, J.5    Zhang, L.-L.6    Huang, Z.-Y.7    Wang, J.-Z.8
  • 62
    • 79958097582 scopus 로고    scopus 로고
    • Kainic acid-induced neurotoxicity: targeting glial responses and glia-derived cytokines
    • Zhang X.-M., Zhu J. Kainic acid-induced neurotoxicity: targeting glial responses and glia-derived cytokines. Curr. Neuropharmacol. 2011, 9:388-398. 10.2174/157015911795596540.
    • (2011) Curr. Neuropharmacol. , vol.9 , pp. 388-398
    • Zhang, X.-M.1    Zhu, J.2
  • 63
    • 77953845018 scopus 로고    scopus 로고
    • Excitotoxicity of TNFalpha derived from KA activated microglia on hippocampal neurons in vitro and in vivo
    • Zhu W., Zheng H., Shao X., Wang W., Yao Q., Li Z. Excitotoxicity of TNFalpha derived from KA activated microglia on hippocampal neurons in vitro and in vivo. J. Neurochem. 2010, 114:386-396. 10.1111/j.1471-4159.2010.06763.x.
    • (2010) J. Neurochem. , vol.114 , pp. 386-396
    • Zhu, W.1    Zheng, H.2    Shao, X.3    Wang, W.4    Yao, Q.5    Li, Z.6


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