Neurotoxicity of glutamate at the concentration released upon spinal cord injury

Neuroscience

Volumn 93, Issue 4, 1999, Pages 1383-1389

  Liu, D ^a   Xu, G Y ^b   Pan, E ^b   McAdoo, D J ^a,b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

Amino acid release; Contusion model; Excitotoxicity; Microdialysis; Rat; Secondary damage

Indexed keywords

ASPARTIC ACID; EXCITOTOXIN; GLUTAMIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LOSS; CONTROLLED STUDY; HISTOLOGY; INTRATHECAL DRUG ADMINISTRATION; MALE; MICRODIALYSIS; NERVE CELL LESION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD INJURY; STRESS;

ANIMALS; ASPARTIC ACID; CONTUSIONS; GLUTAMIC ACID; MALE; MICRODIALYSIS; NERVE DEGENERATION; NEUROTOXINS; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD; SPINAL CORD INJURIES;

EID: 0032791163     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(99)00278-X     Document Type: Article

References (51)

1. Alessandri B., Landolt H., Langemann H., Gregorin J., Hall J., Gratzl O. Application of glutamate in the cortex of rats: a microdialysis study. Acta neurochir. 67:1996;6-12.
2. Benveniste H., Jorgensen M.B., Sandberg M., Christensen T., Hagberg H., Diemer N.H. Ischemic damage in hippocampal CA1 is dependent on glutamate release and intact innervation from CA3. J. cerebr. Blood Flow Metab. 9:1989;629-639.
3. Bullock R., Di X. Synergistic effect of glutamate on secondary brain damage following fluid percussion brain injury in rats. J. Neurotrauma. 14:1997;765.
4. Bullock R., Landolt H., Fujisawa H. Patterns of increased glucose use after extracellular glutamate infusion. J. cerebr. Blood Flow Metab. 13:(Suppl. 1):1993;S578.
5. Bungay P.M., Morrison P.F., Dedrick R.L. Steady-state theory for quantitative microdialysis of solutes and water in vivo and in vitro. Life Sci. 46:1990;105-119.
6. Burde R.M., Schainker B., Kayes J. Acute effect of oral and subcutaneous administration of monosodium glutamate on the arcuate nucleus of the hypothalamus in mice and rats. Nature. 233:1971;58-60.
7. Choi D.W. Glutamate neurotoxicity and diseases of the nervous system. Neuron. 1:1988;623-634.
8. Choi D.W., Maulucci-Gedde M., Kriegstein A.R. Glutamate neurotoxicity in cortical cell culture. J. Neurosci. 7:1987;357-368.
9. Clark G.D. Role of excitatory amino acids in brain injury caused by hypoxia-ischemia, status epilepticus, and hypoglycemia. Clin. Perinatol. 16:1989;459-474.
10. Coyle J.T. Excitatory amino acid neurotoxins. Neurosci. Res. Prog. Bull. 19:1981;358-360.
11. Coyle J.T., Molliver M.E., Kuhar M.J. In situ injection of kainic acid: a new method for selectively lesioning neuronal cell bodies while sparing axons of passage. J. comp. Neurol. 180:1978;301-324.
12. Coyle J.T., Schwarcz R. Lesion of striatal neurones with kainic acid provides a model for Huntington's chorea. Nature. 263:1976;244-246.
13. Faden A.I., Lemke M., Simon R.P., Noble L.J. N-Methyl-D-aspartate antagonist MK801 improves outcome following traumatic spinal cord injury in rats: behavioral, anatomic, and neurochemical studies. J. Neurotrauma. 5:1988;33-45.
14. Faden A.I., Simon R.P. A potential role for excitotoxins in the pathophysiology of spinal cord injury. Ann. Neurol. 23:1988;623-626.
15. Farooque M., Hillered L., Holtz A., Olsson Y. Changes of extracellular levels of amino acids after graded compression trauma to the spinal cord: an experimental study in the rat using microdialysis. J. Neurotrauma. 13:1996;537-548.
16. Fujisawa H., Dawson D., Browne S.E., MacKay K.B., Bullock R., McCulloch J. Pharmacological modification of glutamate neurotoxicity in vivo. Brain Res. 629:1993;73-78.
17. Garrison C.J., Dougherty P.M., Kajander K.C., Carlton S.M. Staining of glial fibrillary acidic protein (GFAP) in lumbar spinal cord increases following a sciatic nerve constriction injury. Brain Res. 565:1991;1-7.
18. Hattori T., McGeer E.G. Fine structural changes in the rat striatum after local injections of kainic acid. Brain Res. 129:1977;174-180.
19. Jacobson I., Sandberg M., Hamberger A. Mass transfer in brain dialysis devices - a new method for the estimation of extracellular amino acids concentration. J. Neurosci. Meth. 15:1985;263-268.
20. 14C glutamate autoradiography. J. cerebr. Blood Flow Metab. 13:(Suppl. 1):1993;S753.
21. Liu D. Generation and detection of hydroxyl radicals in vivo in rat spinal cord by microdialysis administration of Fenton's reagents and microdialysis sampling. J. biochem. biophys. Meth. 27:1993;281-291.
22. Liu D. An experimental model combining microdialysis with electrophysiology, histology, and neurochemistry for studying excitotoxicity in spinal cord injury. Effects of NMDA and kainate. Molec. chem. Neuropath. 23:1994;77-92.
23. Liu D., McAdoo D.J. Methylprednisolone reduces excitatory amino acid release following experimental spinal cord injury. Brain Res. 609:1993;293-297.
24. Liu D., McAdoo D.J. An experimental model combining microdialysis with electrophysiology, histology, and neurochemistry for exploring mechanisms of secondary damage in spinal cord injury: effects of potassium. J. Neurotrauma. 10:1993;349-362.
25. Liu D. and McAdoo D. J. (1995) A microdialysis model for identifying agents of secondary damage in spinal cord injury. In CRC Series in Membrane-Linked Diseases. Central Nervous System Trauma Research Techniques (eds Ohnishi S. T. and Ohnishi T.), Chap. 29, pp. 405-413. CRC, New York.
26. Liu D., Thangnipon W., McAdoo D.J. Excitatory amino acids rise to toxic levels upon impact injury to the rat spinal cord. Brain Res. 547:1991;344-348.
27. Liu D., Yang R., Yan X., McAdoo D.J. Hydroxyl radical generated in vivo kills neurons in the rat spinal cord: electrophysiological, histological and neurochemical results. J. Neurochem. 62:1994;37-44.
28. Liu S., Ruenes G.L., Yezierski R.P. NMDA and non-NMDA receptor antagonists protect against excitotoxic injury in the rat spinal cord. Brain Res. 756:1997;160-167.
29. Mangano R.M., Schwarcz R. Chronic infusion of endogenous excitatory amino acids into rat striatum and hippocampus. Brain Res. Bull. 10:1983;47-51.
30. Matuszewski B.K., Givens R.S., Srinivasachar K., Carlson R.G., Higuchi T. N-Substituted 1-cyanobenz[f]isoindole: evaluation of fluorescence efficiencies of a new fluorogenic label for primary amines and amino acids. Analyt. Chem. 59:1987;1102-1105.
31. Mayer M.L., Westbrook G.L. The action of N-methyl-D-aspartic acid on mouse spinal neurones in culture. J. Physiol. 361:1985;65-90.
32. McBean G.J., Roberts P.J. Chronic infusion of L-glutamate causes neurotoxicity in rat striatum. Brain Res. 290:1984;372-375.
33. McIntosh T.K., Hayes R.L., Dewitt D.S., Agura V., Faden A.I. Endogenous opioids may mediate secondary damage after experimental brain injury. Am. J. Physiol. 253:1987;E565-E574.
34. Montigny P. De., Stobaugh J.F., Givens R.S., Carlson R.G., Srinivasachar K., Sternson L.A., Higuchi T. Naphthalene-2,3-dicarboxaldehyde/cyanide ion: a rationally designed fluorogenic reagent for primary amines. Analyt. Chem. 59:1987;1096-1101.
35. Morrison P.F., Bungay P.M., Hsiao H.K., Ball B.A., Mefford I.N., Dedrick R.L. Quantitative microdialysis: analysis of transients and application to pharmacokinetics in brain. J. Neurochem. 57:1991;103-119.
36. Nowak L., Bregestovski P., Ascher P., Herbert A., Prochiantz A. Magnesium gates glutamate-activated channels in mouse central neurones. Nature. 307:1984;462-465.
37. Olney J. W. (1978) Neurotoxicity of excitatory amino acids. In Kainic Acid as a Tool in Neurobiology (eds McGeer E. G. et al.), pp. 95 - 121. Raven, New York.
38. Olney J.W., Ho O.L., Rhee V. Cytotoxic effects of acidic and sulphur containing amino acids on the infant mouse central nervous system. Expl Brain Res. 14:1971;61-76.
39. Olney J.W., Sharpe L.G. Brain lesions in an infant rhesus monkey treated with monosodium glutamate. Science. 166:1969;386-388.
40. Osterholm J.L., Mathews G.J. A proposed biochemical mechanism for traumatic spinal cord hemorrhagic necrosis. Successful therapy for severe injuries by metabolic blockade. Trans. Am. neurol. Assoc. 96:1971;187-191.
41. Panter S.S., Yum S.W., Faden A.I. Alteration in extracellular amino acids after traumatic spinal cord injury. Ann. Neurol. 27:1990;96-99.
42. Pisharodi M., Nauta H.J.W. An animal model for neuron-specific spinal cord lesions by the microinjection of N-methylaspartate, kainic acid, and quisqualic acid. Appl. Neurophysiol. 48:1985;226-233.
43. Regan R.F., Choi D.W. Glutamate neurotoxicity in spinal cord cell culture. Neuroscience. 43:1991;585-591.
44. Skilling S.R., Smullin D.H., Beitz A.J., Larson A.A. Extracellular amino acid concentrations in the dorsal spinal cord of freely moving rats following veratridine and nociceptive stimulation. J. Neurochem. 51:1988;127-132.
45. Sloviter R.S., Dempster D.W. "Epileptic" brain damage is replicated qualitatively in the rat hippocampus by central injection of glutamate or aspartate but not by GABA or acetylcholine. Brain Res. Bull. 15:1985;39-60.
46. Stewart G.R., Olney J.W., Pathikonda M., Snider W.D. Excitotoxicity in the embryonic chick spinal cord. Ann. Neurol. 30:1991;756-758.
47. Wang Y., Wong S.L., Sawchuk R.J. Microdialysis calibration using retrodialysis and zero-net flux: application to a study of the distribution of zidovudine to rabbit cerebrospinal fluid and thalamus. Pharmaceut. Res. 10:1993;1411-1419.
48. Wrathall J.R., Teng Y.D., Choiniere D. Amelioration of functional deficits from spinal cord trauma with systemically administered NBQX, an antagonist of non-N-methyl-D-aspartate receptors. Expl Neurol. 137:1996;119-126.
49. Wrathall J.R., Teng Y.D., Choiniere D., Mundt D.J. Evidence that local non-NMDA receptors contribute to functional deficits in contusive spinal cord injury. Brain Res. 586:1992;140-143.
50. Xu G.-Y. Jr, McAdoo D.J., Hughes M.G., Robak R., de Castro J. Considerations in the determination by microdialysis of resting extracellular amino acid concentrations and release upon spinal cord injury. Neuroscience. 86:1998;1011-1021.
51. Yezierski R.P., Santana M., Park S.-H., Madsen P.W. Neuronal degeneration and cavitation following intraspinal injections of quisqualic acid in the rat. J. Neurotrauma. 4:1993;445-456.