메뉴 건너뛰기




Volumn 31, Issue 21, 2014, Pages 1800-1806

A toll-like receptor 9 antagonist improves bladder function and white matter sparing in spinal cord injury

Author keywords

CpG ODN; inflammation; pattern recognition receptors; regeneration; traumatic spinal cord injury

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE; CYTIDINE PHOSPHATE GUANOSINE OLIGODEOXYNUCLEOTIDE 2088; TOLL LIKE RECEPTOR 9; TOLL LIKE RECEPTOR AGONIST; UNCLASSIFIED DRUG; OLIGODEOXYRIBONUCLEOTIDE;

EID: 84908637880     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2014.3357     Document Type: Article
Times cited : (17)

References (38)
  • 1
    • 0022598140 scopus 로고
    • ABC of spinal cord injury. Ur-ological management
    • Grundy, D., and Russell, J. (1986). ABC of spinal cord injury. Ur-ological management. Br. Med. J. (Clin. Res. Ed.). 292, 249-253.
    • (1986) Br. Med. J. (Clin. Res. Ed.). , vol.292 , pp. 249-253
    • Grundy, D.1    Russell, J.2
  • 2
    • 7244242234 scopus 로고    scopus 로고
    • Targeting recovery: Priorities of the spinal cord-injured population
    • Anderson, K.D. (2004). Targeting recovery: priorities of the spinal cord-injured population. J. Neurotrauma 21, 1371-1383.
    • (2004) J. Neurotrauma , vol.21 , pp. 1371-1383
    • Anderson, K.D.1
  • 3
    • 84867765161 scopus 로고    scopus 로고
    • Harmful and beneficial effects of inflammation after spinal cord injury: Potential therapeutic implications
    • David, S., Lopez-Vales, R., and Wee Yong, V. (2012). Harmful and beneficial effects of inflammation after spinal cord injury: potential therapeutic implications. Handb. Clin. Neurol. 109, 485-502.
    • (2012) Handb. Clin. Neurol. , vol.109 , pp. 485-502
    • David, S.1    Lopez-Vales, R.2    Wee Yong, V.3
  • 4
    • 34250182782 scopus 로고    scopus 로고
    • Toll-like receptor (TLR)-2 and TLR-4 regulate inflammation, gliosis, and myelin sparing after spinal cord injury
    • Kigerl, K.A., Lai, W., Rivest, S., Hart, R.P., Satoskar, A.R., and Po-povich, P.G. (2007). Toll-like receptor (TLR)-2 and TLR-4 regulate inflammation, gliosis, and myelin sparing after spinal cord injury. J. Neurochem. 102, 37-50.
    • (2007) J. Neurochem. , vol.102 , pp. 37-50
    • Kigerl, K.A.1    Lai, W.2    Rivest, S.3    Hart, R.P.4    Satoskar, A.R.5    Po-Povich, P.G.6
  • 5
    • 79957664140 scopus 로고    scopus 로고
    • Anti-neuroinflammatory and neurotrophic effects of combined therapy with annexin II and Reg-2 on injured spinal cord
    • Fang, M., Huang, J.Y., Wang, J., Ling, S.C., Rudd, J.A., Hu, Z.Y., Xu, L.H., Yuan, Z.G., and Han, S. (2011). Anti-neuroinflammatory and neurotrophic effects of combined therapy with annexin II and Reg-2 on injured spinal cord. Neurosignals 19, 16-43.
    • (2011) Neurosignals , vol.19 , pp. 16-43
    • Fang, M.1    Huang, J.Y.2    Wang, J.3    Ling, S.C.4    Rudd, J.A.5    Hu, Z.Y.6    Xu, L.H.7    Yuan, Z.G.8    Han, S.9
  • 7
    • 4444244404 scopus 로고    scopus 로고
    • Neutralization of the chemokine CXCL10 enhances tissue sparing and angiogenesis following spinal cord injury
    • Glaser, J., Gonzalez, R., Perreau, V.M., Cotman, C.W., and Keirstead, H.S. (2004). Neutralization of the chemokine CXCL10 enhances tissue sparing and angiogenesis following spinal cord injury. J. Neurosci. Res. 77, 701-708.
    • (2004) J. Neurosci. Res. , vol.77 , pp. 701-708
    • Glaser, J.1    Gonzalez, R.2    Perreau, V.M.3    Cotman, C.W.4    Keirstead, H.S.5
  • 8
    • 0345688977 scopus 로고    scopus 로고
    • Reducing inflammation decreases secondary degeneration and functional deficit after spinal cord injury
    • Gonzalez, R., Glaser, J., Liu, M.T., Lane, T.E., and Keirstead, H.S. (2003). Reducing inflammation decreases secondary degeneration and functional deficit after spinal cord injury. Exp. Neurol. 184, 456-463.
    • (2003) Exp. Neurol. , vol.184 , pp. 456-463
    • Gonzalez, R.1    Glaser, J.2    Liu, M.T.3    Lane, T.E.4    Keirstead, H.S.5
  • 9
    • 35048890497 scopus 로고    scopus 로고
    • Therapeutic neutralization of CXCL10 decreases secondary degeneration and functional deficit after spinal cord injury in mice
    • Gonzalez, R., Hickey, M.J., Espinosa, J.M., Nistor, G., Lane, T.E., and Keirstead, H.S. (2007). Therapeutic neutralization of CXCL10 decreases secondary degeneration and functional deficit after spinal cord injury in mice. Regen. Med. 2, 771-783.
    • (2007) Regen. Med. , vol.2 , pp. 771-783
    • Gonzalez, R.1    Hickey, M.J.2    Espinosa, J.M.3    Nistor, G.4    Lane, T.E.5    Keirstead, H.S.6
  • 10
    • 80054807341 scopus 로고    scopus 로고
    • Prevention of both neutrophil and monocyte recruitment promotes recovery after spinal cord injury
    • Lee, S.M., Rosen, S., Weinstein, P., van Rooijen, N., and Noble-Haeusslein, L.J. (2011). Prevention of both neutrophil and monocyte recruitment promotes recovery after spinal cord injury. J. Neuro-trauma 28, 1893-1907.
    • (2011) J. Neuro-trauma , vol.28 , pp. 1893-1907
    • Lee, S.M.1    Rosen, S.2    Weinstein, P.3    Van Rooijen, N.4    Noble-Haeusslein, L.J.5
  • 11
    • 0036841178 scopus 로고    scopus 로고
    • Broad expression of Toll-like receptors in the human central nervous system
    • Bsibsi, M., Ravid, R., Gveric, D., and van Noort, J.M. (2002). Broad expression of Toll-like receptors in the human central nervous system. J. Neuropathol. Exp. Neurol. 61, 1013-1021.
    • (2002) J. Neuropathol. Exp. Neurol. , vol.61 , pp. 1013-1021
    • Bsibsi, M.1    Ravid, R.2    Gveric, D.3    Van Noort, J.M.4
  • 12
    • 44849137950 scopus 로고    scopus 로고
    • Toll-like receptor ligands induce human T cell activation and death, a model for HIV pathogenesis
    • Funderburg, N., Luciano, A.A., Jiang, W., Rodriguez, B., Sieg, S.F., and Lederman, M.M. (2008). Toll-like receptor ligands induce human T cell activation and death, a model for HIV pathogenesis. PloS One 3, e1915.
    • (2008) PloS One , vol.3 , pp. e1915
    • Funderburg, N.1    Luciano, A.A.2    Jiang, W.3    Rodriguez, B.4    Sieg, S.F.5    Lederman, M.M.6
  • 13
    • 0141705297 scopus 로고    scopus 로고
    • Toll-like receptors stimulate human neutrophil function
    • Hayashi, F., Means, T.K., and Luster, A.D. (2003). Toll-like receptors stimulate human neutrophil function. Blood 102, 2660-2669.
    • (2003) Blood , vol.102 , pp. 2660-2669
    • Hayashi, F.1    Means, T.K.2    Luster, A.D.3
  • 14
    • 84055181328 scopus 로고    scopus 로고
    • Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway
    • He, S., Liang, Y., Shao, F., and Wang, X. (2011). Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway. Proc. Natl. Acad. Sci. U. S. A. 108, 20054-20059.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 20054-20059
    • He, S.1    Liang, Y.2    Shao, F.3    Wang, X.4
  • 15
    • 66249147220 scopus 로고    scopus 로고
    • Endogenous signals initiating inflammation in the injured nervous system
    • Pineau, I., and Lacroix, S. (2009). Endogenous signals initiating inflammation in the injured nervous system. Glia 57, 351-361.
    • (2009) Glia , vol.57 , pp. 351-361
    • Pineau, I.1    Lacroix, S.2
  • 16
    • 0037177825 scopus 로고    scopus 로고
    • Novel signal trans-duction pathway utilized by extracellular HSP70: Role of toll-like receptor (TLR) 2 and TLR4
    • Asea, A., Rehli, M., Kabingu, E., Boch, J.A., Bare, O., Auron, P.E., Stevenson, M.A., and Calderwood, S.K. (2002). Novel signal trans-duction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4. J. Biol. Chem. 277, 15028-15034.
    • (2002) J. Biol. Chem. , vol.277 , pp. 15028-15034
    • Asea, A.1    Rehli, M.2    Kabingu, E.3    Boch, J.A.4    Bare, O.5    Auron, P.E.6    Stevenson, M.A.7    Calderwood, S.K.8
  • 17
    • 34548409654 scopus 로고    scopus 로고
    • Toll-like receptors in the brain and their potential roles in neuropathology
    • Crack, P.J., and Bray, P.J. (2007). Toll-like receptors in the brain and their potential roles in neuropathology. Immunol. Cell Biol. 85, 476-480.
    • (2007) Immunol. Cell Biol. , vol.85 , pp. 476-480
    • Crack, P.J.1    Bray, P.J.2
  • 19
    • 79959634861 scopus 로고    scopus 로고
    • Pattern recognition receptors and the innate immune response to viral infection
    • Thompson, M.R., Kaminski, J.J., Kurt-Jones, E.A., and Fitzgerald, K.A. (2011). Pattern recognition receptors and the innate immune response to viral infection. Viruses 3, 920-940.
    • (2011) Viruses , vol.3 , pp. 920-940
    • Thompson, M.R.1    Kaminski, J.J.2    Kurt-Jones, E.A.3    Fitzgerald, K.A.4
  • 21
    • 84876330870 scopus 로고    scopus 로고
    • A toll-like receptor 9 antagonist reduces pain hypersensitivity and the inflammatory response in spinal cord injury
    • David, B.T., Ratnayake, A., Amarante, M.A., Reddy, N.P., Dong, W., Sampath, S., Heary, R.F., and Elkabes, S. (2013). A toll-like receptor 9 antagonist reduces pain hypersensitivity and the inflammatory response in spinal cord injury. Neurobiol. Dis. 54, 194-205.
    • (2013) Neurobiol. Dis. , vol.54 , pp. 194-205
    • David, B.T.1    Ratnayake, A.2    Amarante, M.A.3    Reddy, N.P.4    Dong, W.5    Sampath, S.6    Heary, R.F.7    Elkabes, S.8
  • 22
    • 33645983692 scopus 로고    scopus 로고
    • Basso Mouse Scale for locomotion detects differences in recovery after spinal cord injury in five common mouse strains
    • Basso, D.M., Fisher, L.C., Anderson, A.J., Jakeman, L.B., McTigue, D.M., and Popovich, P.G. (2006). Basso Mouse Scale for locomotion detects differences in recovery after spinal cord injury in five common mouse strains. J. Neurotrauma 23, 635-659.
    • (2006) J. Neurotrauma , vol.23 , pp. 635-659
    • Basso, D.M.1    Fisher, L.C.2    Anderson, A.J.3    Jakeman, L.B.4    McTigue, D.M.5    Popovich, P.G.6
  • 23
    • 70349740885 scopus 로고    scopus 로고
    • Bilateral cervical contusion spinal cord injury in rats
    • Anderson, K.D., Sharp, K.G., and Steward, O. (2009). Bilateral cervical contusion spinal cord injury in rats. Exp. Neurol. 220, 9-22.
    • (2009) Exp. Neurol. , vol.220 , pp. 9-22
    • Anderson, K.D.1    Sharp, K.G.2    Steward, O.3
  • 24
    • 77957810911 scopus 로고    scopus 로고
    • Deficits in bladder function following spinal cord injury vary depending on the level of the injury
    • David, B.T., and Steward, O. (2010). Deficits in bladder function following spinal cord injury vary depending on the level of the injury. Exp. Neurol. 226, 128-135.
    • (2010) Exp. Neurol. , vol.226 , pp. 128-135
    • David, B.T.1    Steward, O.2
  • 25
    • 0035863056 scopus 로고    scopus 로고
    • Coordination of the bladder detrusor and the external urethral sphincter in a rat model of spinal cord injury: Effect of injury severity
    • Pikov, V., and Wrathall, J.R. (2001). Coordination of the bladder detrusor and the external urethral sphincter in a rat model of spinal cord injury: effect of injury severity. J. Neurosci. 21, 559-569.
    • (2001) J. Neurosci. , vol.21 , pp. 559-569
    • Pikov, V.1    Wrathall, J.R.2
  • 26
    • 33748427477 scopus 로고    scopus 로고
    • Intraspinal administration of an antibody against CD81 enhances functional recovery and tissue sparing after experimental spinal cord injury
    • Dijkstra, S., Duis, S., Pans, I.M., Lankhorst, A.J., Hamers, F.P., Veldman, H., Bar, P.R., Gispen, W.H., Joosten, E.A., and Geisert, E.E., Jr. (2006). Intraspinal administration of an antibody against CD81 enhances functional recovery and tissue sparing after experimental spinal cord injury. Exp. Neurol. 202, 57-66.
    • (2006) Exp. Neurol. , vol.202 , pp. 57-66
    • Dijkstra, S.1    Duis, S.2    Pans, I.M.3    Lankhorst, A.J.4    Hamers, F.P.5    Veldman, H.6    Bar, P.R.7    Gispen, W.H.8    Joosten, E.A.9    Geisert, E.E.10
  • 27
    • 84912086940 scopus 로고    scopus 로고
    • National Institutes of Health, Bethesda, Md
    • Rasband, W., 1997-2007. ImageJ. Vol. 1.38x. National Institutes of Health, Bethesda, Md.
    • (1997) ImageJ. Vol. 1.38x
    • Rasband, W.1
  • 28
    • 0032739262 scopus 로고    scopus 로고
    • Sys-temically administered interleukin-10 reduces tumor necrosis factor-alpha production and significantly improves functional recovery following traumatic spinal cord injury in rats
    • Bethea, J.R., Nagashima, H., Acosta, M.C., Briceno, C., Gomez, F., Marcillo, A.E., Loor, K., Green, J., and Dietrich, W.D. (1999). Sys-temically administered interleukin-10 reduces tumor necrosis factor-alpha production and significantly improves functional recovery following traumatic spinal cord injury in rats. J. Neurotrauma 16, 851-863.
    • (1999) J. Neurotrauma , vol.16 , pp. 851-863
    • Bethea, J.R.1    Nagashima, H.2    Acosta, M.C.3    Briceno, C.4    Gomez, F.5    Marcillo, A.E.6    Loor, K.7    Green, J.8    Dietrich, W.D.9
  • 31
    • 79959515864 scopus 로고    scopus 로고
    • Histology of the central nervous system
    • Garman, R.H. (2011). Histology of the central nervous system. Tox-icol. Pathol. 39, 22-35.
    • (2011) Tox-icol. Pathol. , vol.39 , pp. 22-35
    • Garman, R.H.1
  • 33
    • 0042732049 scopus 로고    scopus 로고
    • The consumerSuppl 1, 's perspective and the professional literature: What do persons with spinal cord injury want?
    • Estores, I.M. (2003). The consumerSuppl 1, 's perspective and the professional literature: what do persons with spinal cord injury want? J. Rehabil. Res. Dev. 40, 93-98.
    • (2003) J. Rehabil. Res. Dev. , vol.40 , pp. 93-98
    • Estores, I.M.1
  • 34
    • 7444246133 scopus 로고    scopus 로고
    • Etiology and incidence of rehospitalization after traumatic spinal cord injury: A multicenter analysis
    • Cardenas, D.D., Hoffman, J.M., Kirshblum, S., and McKinley, W. (2004). Etiology and incidence of rehospitalization after traumatic spinal cord injury: a multicenter analysis. Arch. Phys. Med. Rehabil. 85, 1757-1763.
    • (2004) Arch. Phys. Med. Rehabil. , vol.85 , pp. 1757-1763
    • Cardenas, D.D.1    Hoffman, J.M.2    Kirshblum, S.3    McKinley, W.4
  • 36
    • 17644414137 scopus 로고    scopus 로고
    • The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathy
    • Tanga, F.Y., Nutile-McMenemy, N., and DeLeo, J.A. (2005). The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathy. Proc. Natl. Acad. Sci. U. S. A. 102, 5856-5861.
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 5856-5861
    • Tanga, F.Y.1    Nutile-Mcmenemy, N.2    Deleo, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.