-
1
-
-
84863986133
-
Functions of DNA methylation: islands, start sites, gene bodies and beyond
-
Jones PA. Functions of DNA methylation: islands, start sites, gene bodies and beyond. Nat Rev Genet 2012;13:484-92
-
(2012)
Nat Rev Genet
, vol.13
, pp. 484-492
-
-
Jones, P.A.1
-
2
-
-
0035839057
-
The role of DNA methylation in mammalian epigenetics
-
Jones PA, Takai D. The role of DNA methylation in mammalian epigenetics. Science 2001;293:1068-70
-
(2001)
Science
, vol.293
, pp. 1068-1070
-
-
Jones, P.A.1
Takai, D.2
-
3
-
-
0034625064
-
Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a
-
Ramsahoye BH, Biniszkiewicz D, Lyko F, et al. Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a. Proc Natl Acad Sci U S A 2000;97:5237-42
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 5237-5242
-
-
Ramsahoye, B.H.1
Biniszkiewicz, D.2
Lyko, F.3
-
5
-
-
70350046301
-
Rethinking how DNA methylation patterns are maintained
-
Jones PA, Liang G. Rethinking how DNA methylation patterns are maintained. Nat Rev Genet 2009;10:805-811
-
(2009)
Nat Rev Genet
, vol.10
, pp. 805-811
-
-
Jones, P.A.1
Liang, G.2
-
6
-
-
79952258043
-
Nucleosomes containing methylated DNA stabilize DNA methyltransferases 3A/3B and ensure faithful epigenetic inheritance
-
Sharma S, De Carvalho DD, Jeong S, et al. Nucleosomes containing methylated DNA stabilize DNA methyltransferases 3A/3B and ensure faithful epigenetic inheritance. PLoS Genet 2011;7:e1001286
-
(2011)
PLoS Genet
, vol.7
-
-
Sharma, S.1
De Carvalho, D.D.2
Jeong, S.3
-
7
-
-
0035930660
-
Dnmt3L and the establishment of maternal genomic imprints
-
Bourčhis D, Xu GL, Lin CS, et al. Dnmt3L and the establishment of maternal genomic imprints. Science 2001;294:2536-9
-
(2001)
Science
, vol.294
, pp. 2536-2539
-
-
Bourčhis, D.1
Xu, G.L.2
Lin, C.S.3
-
8
-
-
0036333103
-
Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice
-
Hata K, Okano M, Lei H, et al. Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice. Development 2002;129:1983-93
-
(2002)
Development
, vol.129
, pp. 1983-1993
-
-
Hata, K.1
Okano, M.2
Lei, H.3
-
9
-
-
31144449613
-
Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2
-
Goll MG, Kirpekar F, Maggert KA, et al. Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2. Science 2006;311:395-8
-
(2006)
Science
, vol.311
, pp. 395-398
-
-
Goll, M.G.1
Kirpekar, F.2
Maggert, K.A.3
-
10
-
-
77955884641
-
RNA methylation by Dnmt2 protects transfer RNAs against stress-induced cleavage
-
Schaefer M, Pollex T, Hanna K, et al. RNA methylation by Dnmt2 protects transfer RNAs against stress-induced cleavage. Genes Dev 2010;24:1590-5
-
(2010)
Genes Dev
, vol.24
, pp. 1590-1595
-
-
Schaefer, M.1
Pollex, T.2
Hanna, K.3
-
11
-
-
0025344222
-
A sensitive genetic assay for the detection of cytosine deamination: determination of rate constants and the activation energy
-
Frederico LA, Kunkel TA, Shaw BR. A sensitive genetic assay for the detection of cytosine deamination: determination of rate constants and the activation energy. Biochemistry 1990;29:2532-7
-
(1990)
Biochemistry
, vol.29
, pp. 2532-2537
-
-
Frederico, L.A.1
Kunkel, T.A.2
Shaw, B.R.3
-
12
-
-
0038576158
-
The power and the promise of DNA methylation markers
-
Laird PW. The power and the promise of DNA methylation markers. Nat Rev Cancer 2003;3:253-66
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 253-266
-
-
Laird, P.W.1
-
13
-
-
0028358421
-
The rate of hydrolytic deamination of 5-methylcytosine in double-stranded DNA
-
Shen JC, Rideout WM 3rd, Jones PA. The rate of hydrolytic deamination of 5-methylcytosine in double-stranded DNA. Nucleic Acids Res 1994;22:972-6
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 972-976
-
-
Shen, J.C.1
Rideout, W.M.2
Jones, P.A.3
-
14
-
-
84902298158
-
The role of 5-hydroxymethylcytosine in human cancer
-
Pfeifer GP, Xiong W, Hahn MA, et al. The role of 5-hydroxymethylcytosine in human cancer. Cell Tissue Res 2014;356:631-41
-
(2014)
Cell Tissue Res
, vol.356
, pp. 631-641
-
-
Pfeifer, G.P.1
Xiong, W.2
Hahn, M.A.3
-
15
-
-
84913610950
-
5-hydroxymethylcytosine: a potential therapeutic target in cancer
-
Rodger EJ, Chatterjee A, Morison IM. 5-hydroxymethylcytosine: a potential therapeutic target in cancer. Epigenomics 2014;6:503-14
-
(2014)
Epigenomics
, vol.6
, pp. 503-514
-
-
Rodger, E.J.1
Chatterjee, A.2
Morison, I.M.3
-
16
-
-
84864129535
-
Distribution of 5-hydroxymethylcytosine in different human tissues
-
Li W, Liu M. Distribution of 5-hydroxymethylcytosine in different human tissues. J Nucleic Acids 2011;2011:870726
-
(2011)
J Nucleic Acids
, vol.2011
-
-
Li, W.1
Liu, M.2
-
17
-
-
84927698415
-
Loss of 5-hydroxymethylcytosine in cancer: cause or consequence?
-
Ficz G, Gribben JG. Loss of 5-hydroxymethylcytosine in cancer: cause or consequence? Genomics 2014;104:352-7
-
(2014)
Genomics
, vol.104
, pp. 352-357
-
-
Ficz, G.1
Gribben, J.G.2
-
18
-
-
84874252793
-
Dynamics of 5-hydroxymethylcytosine and chromatin marks in Mammalian neurogenesis
-
Hahn MA, Qiu R, Wu X, et al. Dynamics of 5-hydroxymethylcytosine and chromatin marks in Mammalian neurogenesis. Cell Rep 2013;3:291-300
-
(2013)
Cell Rep
, vol.3
, pp. 291-300
-
-
Hahn, M.A.1
Qiu, R.2
Wu, X.3
-
19
-
-
84876794613
-
5-hydroxymethylcytosine and its potential roles in development and cancer
-
Pfeifer GP, Kadam S, Jin SG. 5-hydroxymethylcytosine and its potential roles in development and cancer. Epigenetics Chromatin 2013;6:10
-
(2013)
Epigenetics Chromatin
, vol.6
, pp. 10
-
-
Pfeifer, G.P.1
Kadam, S.2
Jin, S.G.3
-
20
-
-
84856058152
-
Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers
-
Haffner MC, Chaux A, Meeker AK, et al. Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers. Oncotarget 2011;2:627-37
-
(2011)
Oncotarget
, vol.2
, pp. 627-637
-
-
Haffner, M.C.1
Chaux, A.2
Meeker, A.K.3
-
21
-
-
84864463122
-
Low values of 5-hydroxymethylcytosine (5hmC), the "sixth base," are associated with anaplasia in human brain tumors
-
Kraus TF, Globisch D, Wagner M, et al. Low values of 5-hydroxymethylcytosine (5hmC), the "sixth base," are associated with anaplasia in human brain tumors. Int J Cancer 2012;131:1577-90
-
(2012)
Int J Cancer
, vol.131
, pp. 1577-1590
-
-
Kraus, T.F.1
Globisch, D.2
Wagner, M.3
-
22
-
-
84863393235
-
Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation
-
Kudo Y, Tateishi K, Yamamoto K, et al. Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation. Cancer Sci 2012;103:670-6
-
(2012)
Cancer Sci
, vol.103
, pp. 670-676
-
-
Kudo, Y.1
Tateishi, K.2
Yamamoto, K.3
-
23
-
-
84875745673
-
Interplay between the cancer genome and epigenome
-
Shen H, Laird PW. Interplay between the cancer genome and epigenome. Cell 2013;153:38-55
-
(2013)
Cell
, vol.153
, pp. 38-55
-
-
Shen, H.1
Laird, P.W.2
-
24
-
-
34249026300
-
High-resolution profiling of histone methylations in the human genome
-
Barski A, Cuddapah S, Cui K, et al. High-resolution profiling of histone methylations in the human genome. Cell 2007;129:823-37
-
(2007)
Cell
, vol.129
, pp. 823-837
-
-
Barski, A.1
Cuddapah, S.2
Cui, K.3
-
25
-
-
42149146774
-
DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells
-
Steger DJ, Lefterova MI, Ying L, et al. DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells. Mol Cell Biol 2008;28:2825-39
-
(2008)
Mol Cell Biol
, vol.28
, pp. 2825-2839
-
-
Steger, D.J.1
Lefterova, M.I.2
Ying, L.3
-
26
-
-
84655162785
-
Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-associated domains
-
Berman BP, Weisenberger DJ, Aman JF, et al. Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-associated domains. Nat Genet 2012;44:40-6
-
(2012)
Nat Genet
, vol.44
, pp. 40-46
-
-
Berman, B.P.1
Weisenberger, D.J.2
Aman, J.F.3
-
27
-
-
0020459647
-
Hypomethylation of HeLa cell DNA and the absence of 5-methylcytosine in SV40 and adenovirus (type 2) DNA: analysis by HPLC
-
Diala ES, Hoffman RM. Hypomethylation of HeLa cell DNA and the absence of 5-methylcytosine in SV40 and adenovirus (type 2) DNA: analysis by HPLC. Biochem Biophys Res Commun 1982;107:19-26
-
(1982)
Biochem Biophys Res Commun
, vol.107
, pp. 19-26
-
-
Diala, E.S.1
Hoffman, R.M.2
-
28
-
-
0020489781
-
Amount and distribution of 5-methylcytosine in human DNA from different types of tissues of cells
-
Ehrlich M, Gama-Sosa MA, Huang LH, et al. Amount and distribution of 5-methylcytosine in human DNA from different types of tissues of cells. Nucleic Acids Res 1982;10:2709-21
-
(1982)
Nucleic Acids Res
, vol.10
, pp. 2709-2721
-
-
Ehrlich, M.1
Gama-Sosa, M.A.2
Huang, L.H.3
-
29
-
-
0019884371
-
5-Methylcytosine in eukaryotic DNA
-
Ehrlich M, Wang RY. 5-Methylcytosine in eukaryotic DNA. Science 1981;212:1350-7
-
(1981)
Science
, vol.212
, pp. 1350-1357
-
-
Ehrlich, M.1
Wang, R.Y.2
-
30
-
-
0020699979
-
Hypomethylation distinguishes genes of some human cancers from their normal counterparts
-
Feinberg AP, Vogelstein B. Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature 1983;301:89-92
-
(1983)
Nature
, vol.301
, pp. 89-92
-
-
Feinberg, A.P.1
Vogelstein, B.2
-
32
-
-
79960927422
-
Increased methylation variation in epigenetic domains across cancer types
-
Hansen KD, Timp W, Bravo HC, et al. Increased methylation variation in epigenetic domains across cancer types. Nat Genet 2011;43:768-75
-
(2011)
Nat Genet
, vol.43
, pp. 768-775
-
-
Hansen, K.D.1
Timp, W.2
Bravo, H.C.3
-
33
-
-
70450217879
-
Human DNA methylomes at base resolution show widespread epigenomic differences
-
Lister R, Pelizzola M, Dowen RH, et al. Human DNA methylomes at base resolution show widespread epigenomic differences. Nature 2009;462:315-22
-
(2009)
Nature
, vol.462
, pp. 315-322
-
-
Lister, R.1
Pelizzola, M.2
Dowen, R.H.3
-
34
-
-
29244490041
-
Analysis of repetitive element DNA methylation by MethyLight
-
Weisenberger DJ, Campan M, Long TI, et al. Analysis of repetitive element DNA methylation by MethyLight. Nucleic Acids Res 2005;33:6823-36
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 6823-6836
-
-
Weisenberger, D.J.1
Campan, M.2
Long, T.I.3
-
35
-
-
59149084538
-
The human colon cancer methylome shows similar hypo-and hypermethylation at conserved tissue-specific CpG island shores
-
Irizarry RA, Ladd-Acosta C, Wen B, et al. The human colon cancer methylome shows similar hypo-and hypermethylation at conserved tissue-specific CpG island shores. Nat Genet 2009;41:178-86
-
(2009)
Nat Genet
, vol.41
, pp. 178-186
-
-
Irizarry, R.A.1
Ladd-Acosta, C.2
Wen, B.3
-
36
-
-
84862622426
-
The cancer epigenome: its origins, contributions to tumorigenesis, and translational implications
-
Baylin SB. The cancer epigenome: its origins, contributions to tumorigenesis, and translational implications. Proc Am Thorac Soc 2012;9:64-5
-
(2012)
Proc Am Thorac Soc
, vol.9
, pp. 64-65
-
-
Baylin, S.B.1
-
37
-
-
0035870248
-
A gene hypermethylation profile of human cancer
-
Esteller M, Corn PG, Baylin SB, et al. A gene hypermethylation profile of human cancer. Cancer Res 2001;61:3225-9
-
(2001)
Cancer Res
, vol.61
, pp. 3225-3229
-
-
Esteller, M.1
Corn, P.G.2
Baylin, S.B.3
-
38
-
-
0032827113
-
Roles of cell division and gene transcription in the methylation of CpG islands
-
Bender CM, Gonzalgo ML, Gonzales FA, et al. Roles of cell division and gene transcription in the methylation of CpG islands. Mol Cell Biol 1999;19:6690-8
-
(1999)
Mol Cell Biol
, vol.19
, pp. 6690-6698
-
-
Bender, C.M.1
Gonzalgo, M.L.2
Gonzales, F.A.3
-
39
-
-
84868198427
-
Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia
-
Kulis M, Heath S, Bibikova M, et al. Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia. Nat Genet 2012;44:1236-42
-
(2012)
Nat Genet
, vol.44
, pp. 1236-1242
-
-
Kulis, M.1
Heath, S.2
Bibikova, M.3
-
40
-
-
84907997839
-
Gene body methylation can alter gene expression and is a therapeutic target in cancer
-
Yang X, Han H, De Carvalho DD, et al. Gene body methylation can alter gene expression and is a therapeutic target in cancer. Cancer Cell 2014;26:577-90
-
(2014)
Cancer Cell
, vol.26
, pp. 577-590
-
-
Yang, X.1
Han, H.2
De Carvalho, D.D.3
-
41
-
-
78751662908
-
The Polycomb complex PRC2 and its mark in life
-
Margueron R, Reinberg D. The Polycomb complex PRC2 and its mark in life. Nature 2011;469:343-9
-
(2011)
Nature
, vol.469
, pp. 343-349
-
-
Margueron, R.1
Reinberg, D.2
-
42
-
-
33846576622
-
Epigenetic stem cell signature in cancer
-
Widschwendter M, Fiegl H, Egle D, et al. Epigenetic stem cell signature in cancer. Nat Genet 2007;39:157-8
-
(2007)
Nat Genet
, vol.39
, pp. 157-158
-
-
Widschwendter, M.1
Fiegl, H.2
Egle, D.3
-
43
-
-
80054790080
-
DNA methylation: superior or subordinate in the epigenetic hierarchy?
-
Jin B, Li Y, Robertson KD. DNA methylation: superior or subordinate in the epigenetic hierarchy? Genes Cancer 2011;2:607-17
-
(2011)
Genes Cancer
, vol.2
, pp. 607-617
-
-
Jin, B.1
Li, Y.2
Robertson, K.D.3
-
44
-
-
84856549042
-
Genome-scale analysis of aberrant DNA methylation in colorectal cancer
-
Hinoue T, Weisenberger DJ, Lange CP, et al. Genome-scale analysis of aberrant DNA methylation in colorectal cancer. Genome Res 2012;22:271-82
-
(2012)
Genome Res
, vol.22
, pp. 271-282
-
-
Hinoue, T.1
Weisenberger, D.J.2
Lange, C.P.3
-
45
-
-
77952108366
-
Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma
-
Noushmehr H, Weisenberger DJ, Diefes K, et al. Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell 2010;17:510-22
-
(2010)
Cancer Cell
, vol.17
, pp. 510-522
-
-
Noushmehr, H.1
Weisenberger, D.J.2
Diefes, K.3
-
46
-
-
34848918829
-
Comparing the DNA hypermethylome with gene mutations in human colorectal cancer
-
Schuebel KE, Chen W, Cope L, et al. Comparing the DNA hypermethylome with gene mutations in human colorectal cancer. PLoS Genet 2007;3:1709-23
-
(2007)
PLoS Genet
, vol.3
, pp. 1709-1723
-
-
Schuebel, K.E.1
Chen, W.2
Cope, L.3
-
47
-
-
0028845142
-
Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
-
Herman JG, Merlo A, Mao L, et al. Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res 1995;55:4525-30
-
(1995)
Cancer Res
, vol.55
, pp. 4525-4530
-
-
Herman, J.G.1
Merlo, A.2
Mao, L.3
-
48
-
-
0029011539
-
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
-
Merlo A, Herman JG, Mao L, et al. 5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nat Med 1995;1:686-92
-
(1995)
Nat Med
, vol.1
, pp. 686-692
-
-
Merlo, A.1
Herman, J.G.2
Mao, L.3
-
49
-
-
0028940722
-
Cell-cycle regulators and cancer
-
Kamb A. Cell-cycle regulators and cancer. Trends Genet 1995;11:136-40
-
(1995)
Trends Genet
, vol.11
, pp. 136-140
-
-
Kamb, A.1
-
50
-
-
84863922124
-
Comprehensive molecular characterization of human colon and rectal cancer
-
The Cancer Genome Atlas Research Network. Comprehensive molecular characterization of human colon and rectal cancer. Nature 2012;487:330-7
-
(2012)
Nature
, vol.487
, pp. 330-337
-
-
-
51
-
-
84916887899
-
Epigenetic alterations of the Wnt signaling pathway in cancer: a mini review
-
Serman L, Nikuseva Martic T, Serman A, et al. Epigenetic alterations of the Wnt signaling pathway in cancer: a mini review. Bosn J Basic Med Sci 2014;14:191-4
-
(2014)
Bosn J Basic Med Sci
, vol.14
, pp. 191-194
-
-
Serman, L.1
Nikuseva Martic, T.2
Serman, A.3
-
52
-
-
84890832947
-
Secreted frizzled related proteins: Implications in cancers
-
Surana R, Sikka S, Cai W, et al. Secreted frizzled related proteins: Implications in cancers. BiochimBiophys Acta 2014;1845:53-65
-
(2014)
BiochimBiophys Acta
, vol.1845
, pp. 53-65
-
-
Surana, R.1
Sikka, S.2
Cai, W.3
-
53
-
-
12144291274
-
Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer
-
Suzuki H, Watkins DN, Jair KW, et al. Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer. Nat Genet 2004;36:417-22
-
(2004)
Nat Genet
, vol.36
, pp. 417-422
-
-
Suzuki, H.1
Watkins, D.N.2
Jair, K.W.3
-
54
-
-
35348992639
-
The genetics of hereditary colon cancer
-
Rustgi AK. The genetics of hereditary colon cancer. Genes Dev 2007;21:2525-38
-
(2007)
Genes Dev
, vol.21
, pp. 2525-2538
-
-
Rustgi, A.K.1
-
55
-
-
16544364390
-
HNPCC and sporadic MSI-H colorectal cancer: a review of the morphological similarities and differences
-
Jass JR. HNPCC and sporadic MSI-H colorectal cancer: a review of the morphological similarities and differences. Fam Cancer 2004;3:93-100
-
(2004)
Fam Cancer
, vol.3
, pp. 93-100
-
-
Jass, J.R.1
-
56
-
-
20844444614
-
Sporadic versus hereditary forms of colorectal cancer with the DNA microsatellite instability phenotype: to 'lump' or 'split'?
-
Jass JR. Sporadic versus hereditary forms of colorectal cancer with the DNA microsatellite instability phenotype: to 'lump' or 'split'? Fam Cancer 2004;3:83
-
(2004)
Fam Cancer
, vol.3
, pp. 83
-
-
Jass, J.R.1
-
57
-
-
55849140517
-
Molecular characterization of MSI-H colorectal cancer by MLHI promoter methylation, immunohistochemistry, and mismatch repair germline mutation screening
-
Poynter JN, Siegmund KD, Weisenberger DJ, et al. Molecular characterization of MSI-H colorectal cancer by MLHI promoter methylation, immunohistochemistry, and mismatch repair germline mutation screening. Cancer Epidemiol Biomarkers Prev 2008;17:3208-15
-
(2008)
Cancer Epidemiol Biomarkers Prev
, vol.17
, pp. 3208-3215
-
-
Poynter, J.N.1
Siegmund, K.D.2
Weisenberger, D.J.3
-
59
-
-
84923188432
-
BRCA1, a 'complex' protein involved in the maintenance of genomic stability
-
Savage KI, Harkin DP. BRCA1, a 'complex' protein involved in the maintenance of genomic stability. FEBS J 2015;282:630-46
-
(2015)
FEBS J
, vol.282
, pp. 630-646
-
-
Savage, K.I.1
Harkin, D.P.2
-
60
-
-
79959838081
-
Integrated genomic analyses of ovarian carcinoma
-
The Cancer Genome Atlas Research Network. Integrated genomic analyses of ovarian carcinoma. Nature 2011;474:609-15
-
(2011)
Nature
, vol.474
, pp. 609-615
-
-
-
61
-
-
84877028141
-
Comprehensive molecular portraits of human breast tumours
-
The Cancer Genome Atlas Research Network. Comprehensive molecular portraits of human breast tumours. Nature 2012;490:61-70
-
(2012)
Nature
, vol.490
, pp. 61-70
-
-
-
62
-
-
84890309501
-
Promoter methylation of BRCA1 in the prognosis of breast cancer: a meta-analysis
-
Wu L, Wang F, Xu R, et al. Promoter methylation of BRCA1 in the prognosis of breast cancer: a meta-analysis. Breast Cancer Res Treat 2013;142:619-27
-
(2013)
Breast Cancer Res Treat
, vol.142
, pp. 619-627
-
-
Wu, L.1
Wang, F.2
Xu, R.3
-
63
-
-
0034066072
-
Disorders in cell circuitry during multistage carcinogenesis: the role of homeostasis
-
Weinstein IB. Disorders in cell circuitry during multistage carcinogenesis: the role of homeostasis. Carcinogenesis 2000;21:857-64
-
(2000)
Carcinogenesis
, vol.21
, pp. 857-864
-
-
Weinstein, I.B.1
-
64
-
-
37249003928
-
Oncogene addiction: setting the stage for molecularly targeted cancer therapy
-
Sharma SV, Settleman J. Oncogene addiction: setting the stage for molecularly targeted cancer therapy. Genes Dev 2007;21:3214-31
-
(2007)
Genes Dev
, vol.21
, pp. 3214-3231
-
-
Sharma, S.V.1
Settleman, J.2
-
65
-
-
0037025173
-
Cancer. Addiction to oncogenes-the Achilles heal of cancer
-
Weinstein IB. Cancer. Addiction to oncogenes-the Achilles heal of cancer. Science 2002;297:63-4
-
(2002)
Science
, vol.297
, pp. 63-64
-
-
Weinstein, I.B.1
-
66
-
-
84861391922
-
DNA methylation screening identifies driver epigenetic events of cancer cell survival
-
De Carvalho DD, Sharma S, You JS, et al. DNA methylation screening identifies driver epigenetic events of cancer cell survival. Cancer Cell 2012;21:655-67
-
(2012)
Cancer Cell
, vol.21
, pp. 655-667
-
-
De Carvalho, D.D.1
Sharma, S.2
You, J.S.3
-
67
-
-
77249137168
-
Principles and challenges of genomewide DNA methylation analysis
-
Laird PW. Principles and challenges of genomewide DNA methylation analysis. Nat Rev Genet 2010;11:191-203
-
(2010)
Nat Rev Genet
, vol.11
, pp. 191-203
-
-
Laird, P.W.1
-
68
-
-
33746756014
-
Comparative isoschizomer profiling of cytosine methylation: the HELP assay
-
Khulan B, Thompson RF, Ye K, et al. Comparative isoschizomer profiling of cytosine methylation: the HELP assay. Genome Res 2006;16:1046-55
-
(2006)
Genome Res
, vol.16
, pp. 1046-1055
-
-
Khulan, B.1
Thompson, R.F.2
Ye, K.3
-
69
-
-
0033563165
-
Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification
-
Toyota M, Ho C, Ahuja N, et al. Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification. Cancer Res 1999;59:2307-12
-
(1999)
Cancer Res
, vol.59
, pp. 2307-2312
-
-
Toyota, M.1
Ho, C.2
Ahuja, N.3
-
70
-
-
0030825309
-
COBRA: a sensitive and quantitative DNA methylation assay
-
Xiong Z, Laird PW. COBRA: a sensitive and quantitative DNA methylation assay. Nucleic Acids Res 1997;25:2532-4
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 2532-2534
-
-
Xiong, Z.1
Laird, P.W.2
-
71
-
-
61449444393
-
Restriction landmark genomic scanning: analysis of CpG islands in genomes by 2D gel electrophoresis
-
Costello JF, Hong C, Plass C, et al. Restriction landmark genomic scanning: analysis of CpG islands in genomes by 2D gel electrophoresis. Methods Mol Biol 2009;507:131-48
-
(2009)
Methods Mol Biol
, vol.507
, pp. 131-148
-
-
Costello, J.F.1
Hong, C.2
Plass, C.3
-
72
-
-
18844465619
-
Methylome profiling of cancer cells by amplification of inter-methylated sites (AIMS)
-
Frigola J, Ribas M, Risques RA, et al. Methylome profiling of cancer cells by amplification of inter-methylated sites (AIMS). Nucleic Acids Res 2002;30:e28
-
(2002)
Nucleic Acids Res
, vol.30
-
-
Frigola, J.1
Ribas, M.2
Risques, R.A.3
-
73
-
-
0031050736
-
Identification and characterization of differentially methylated regions of genomic DNA by methylation-sensitive arbitrarily primed PCR
-
Gonzalgo ML, Liang G, Spruck CH 3rd, et al. Identification and characterization of differentially methylated regions of genomic DNA by methylation-sensitive arbitrarily primed PCR. Cancer Res 1997;57:594-9
-
(1997)
Cancer Res
, vol.57
, pp. 594-599
-
-
Gonzalgo, M.L.1
Liang, G.2
Spruck, C.H.3
-
74
-
-
0034654669
-
MethyLight: a high-throughput assay to measure DNA methylation
-
Eads CA, Danenberg KD, Kawakami K, et al. MethyLight: a high-throughput assay to measure DNA methylation. Nucleic Acids Res 2000;28:E32
-
(2000)
Nucleic Acids Res
, vol.28
, pp. E32
-
-
Eads, C.A.1
Danenberg, K.D.2
Kawakami, K.3
-
75
-
-
0030738231
-
Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE)
-
Gonzalgo ML, Jones PA. Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE). Nucleic Acids Res 1997;25:2529-31
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 2529-2531
-
-
Gonzalgo, M.L.1
Jones, P.A.2
-
76
-
-
0344393468
-
Quantitative GSTP1 methylation and the detection of prostate adenocarcinoma in sextant biopsies
-
Harden SV, Sanderson H, Goodman SN, et al. Quantitative GSTP1 methylation and the detection of prostate adenocarcinoma in sextant biopsies. J Natl Cancer Inst 2003;95:1634-7
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 1634-1637
-
-
Harden, S.V.1
Sanderson, H.2
Goodman, S.N.3
-
77
-
-
0029843950
-
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands
-
Herman JG, Graff JR, Myohanen S, et al. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci U S A 1996;93:9821-6
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 9821-9826
-
-
Herman, J.G.1
Graff, J.R.2
Myohanen, S.3
-
78
-
-
2342557977
-
A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements
-
Yang AS, Estecio MR, Doshi K, et al. A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements. Nucleic Acids Res 2004;32:e38
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Yang, A.S.1
Estecio, M.R.2
Doshi, K.3
-
79
-
-
34948830291
-
High-throughput methylation profiling by MCA coupled to CpG island microarray
-
Estécio MR, Yan PS, Ibrahim AE, et al. High-throughput methylation profiling by MCA coupled to CpG island microarray. Genome Res 2007;17:1529-36
-
(2007)
Genome Res
, vol.17
, pp. 1529-1536
-
-
Estécio, M.R.1
Yan, P.S.2
Ibrahim, A.E.3
-
80
-
-
0033047813
-
Methylation profiling of CpG islands in human breast cancer cells
-
Huang TH, Perry MR, Laux DE. Methylation profiling of CpG islands in human breast cancer cells. Hum Mol Genet 1999;8:459-70
-
(1999)
Hum Mol Genet
, vol.8
, pp. 459-470
-
-
Huang, T.H.1
Perry, M.R.2
Laux, D.E.3
-
81
-
-
43149098062
-
Comprehensive high-throughput arrays for relative methylation (CHARM)
-
Irizarry RA, Ladd-Acosta C, Carvalho B, et al. Comprehensive high-throughput arrays for relative methylation (CHARM). Genome Res 2008;18:780-90
-
(2008)
Genome Res
, vol.18
, pp. 780-790
-
-
Irizarry, R.A.1
Ladd-Acosta, C.2
Carvalho, B.3
-
82
-
-
39149133183
-
Methyl-DNA immunoprecipitation (MeDIP): hunting down the DNA methylome
-
Jacinto FV, Ballestar E, Esteller M. Methyl-DNA immunoprecipitation (MeDIP): hunting down the DNA methylome. BioTechniques 2008;44:35-43
-
(2008)
BioTechniques
, vol.44
, pp. 35-43
-
-
Jacinto, F.V.1
Ballestar, E.2
Esteller, M.3
-
83
-
-
37249026814
-
Genome-wide analysis of DNA methylation patterns
-
Zilberman D, Henikoff S. Genome-wide analysis of DNA methylation patterns. Development 2007;134:3959-65
-
(2007)
Development
, vol.134
, pp. 3959-3965
-
-
Zilberman, D.1
Henikoff, S.2
-
84
-
-
27744443057
-
Methylated-CpG island recovery assay: a new technique for the rapid detection of methylated-CpG islands in cancer
-
Rauch T, Pfeifer GP. Methylated-CpG island recovery assay: a new technique for the rapid detection of methylated-CpG islands in cancer. Lab Invest 2005;85:1172-80
-
(2005)
Lab Invest
, vol.85
, pp. 1172-1180
-
-
Rauch, T.1
Pfeifer, G.P.2
-
85
-
-
80053304450
-
High density DNA methylation array with single CpG site resolution
-
Bibikova M, Barnes B, Tsan C, et al. High density DNA methylation array with single CpG site resolution. Genomics 2011;98:288-95
-
(2011)
Genomics
, vol.98
, pp. 288-295
-
-
Bibikova, M.1
Barnes, B.2
Tsan, C.3
-
86
-
-
61449477534
-
GoldenGate assay for DNA methylation profiling
-
Bibikova M, Fan JB. GoldenGate assay for DNA methylation profiling. Methods Mol Biol. 2009;507:149-163
-
(2009)
Methods Mol Biol
, vol.507
, pp. 149-163
-
-
Bibikova, M.1
Fan, J.B.2
-
88
-
-
84856306090
-
Genome-wide DNA methylation profiling using Infinium(R) assay
-
Bibikova M, Le J, Barnes B, et al. Genome-wide DNA methylation profiling using Infinium(R) assay. Epigenomics 2009;1:177-200
-
(2009)
Epigenomics
, vol.1
, pp. 177-200
-
-
Bibikova, M.1
Le, J.2
Barnes, B.3
-
89
-
-
33644649616
-
High-throughput DNA methylation profiling using universal bead arrays
-
Bibikova M, Lin Z, Zhou L, et al. High-throughput DNA methylation profiling using universal bead arrays. Genome Res 2006;16:383-93
-
(2006)
Genome Res
, vol.16
, pp. 383-393
-
-
Bibikova, M.1
Lin, Z.2
Zhou, L.3
-
90
-
-
84923278597
-
Accurate Measurement of 5-Methylcytosine and 5-Hydroxymethylcytosine in Human Cerebellum DNA by Oxidative Bisulfite on an Array (OxBS-Array)
-
Field SF, Beraldi D, Bachman M, et al. Accurate Measurement of 5-Methylcytosine and 5-Hydroxymethylcytosine in Human Cerebellum DNA by Oxidative Bisulfite on an Array (OxBS-Array). PloS One 2015;10:e0118202
-
(2015)
PloS One
, vol.10
-
-
Field, S.F.1
Beraldi, D.2
Bachman, M.3
-
91
-
-
84927657839
-
Application of a low cost array-based technique-TAB-Array-for quantifying and mapping both 5mC and 5hmC at single base resolution in human pluripotent stem cells
-
Nazor KL, Boland MJ, Bibikova M, et al. Application of a low cost array-based technique-TAB-Array-for quantifying and mapping both 5mC and 5hmC at single base resolution in human pluripotent stem cells. Genomics 2014;104:358-67
-
(2014)
Genomics
, vol.104
, pp. 358-367
-
-
Nazor, K.L.1
Boland, M.J.2
Bibikova, M.3
-
92
-
-
84927714053
-
oxBS-450K: a method for analysing hydroxymethylation using 450K BeadChips
-
Stewart SK, Morris TJ, Guilhamon P, et al. oxBS-450K: a method for analysing hydroxymethylation using 450K BeadChips. Methods 2015;72:9-15
-
(2015)
Methods
, vol.72
, pp. 9-15
-
-
Stewart, S.K.1
Morris, T.J.2
Guilhamon, P.3
-
93
-
-
84924407381
-
An integrative multi-scale analysis of the dynamic DNA methylation landscape in aging
-
Yuan T, Jiao Y, de Jong S, et al. An integrative multi-scale analysis of the dynamic DNA methylation landscape in aging. PLoS Genet 2015;11:e1004996
-
(2015)
PLoS Genet
, vol.11
-
-
Yuan, T.1
Jiao, Y.2
de Jong, S.3
-
94
-
-
27144500218
-
Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis
-
Meissner A, Gnirke A, Bell GW, et al. Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis. Nucleic Acids Res 2005;33:5868-77
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 5868-5877
-
-
Meissner, A.1
Gnirke, A.2
Bell, G.W.3
-
95
-
-
77449153454
-
Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution
-
Gu H, Bock C, Mikkelsen TS, et al. Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution. Nat Methods 2010;7:133-6
-
(2010)
Nat Methods
, vol.7
, pp. 133-136
-
-
Gu, H.1
Bock, C.2
Mikkelsen, T.S.3
-
96
-
-
84870552401
-
Genome-wide mapping of nucleosome positioning and DNA methylation within individual DNA molecules
-
Kelly TK, Liu Y, Lay FD, et al. Genome-wide mapping of nucleosome positioning and DNA methylation within individual DNA molecules. Genome Res 2012;22:2497-506
-
(2012)
Genome Res
, vol.22
, pp. 2497-2506
-
-
Kelly, T.K.1
Liu, Y.2
Lay, F.D.3
-
97
-
-
39749180354
-
DNA methylation biomarkers for blood-based colorectal cancer screening
-
Lofton-Day C, Model F, Devos T, et al. DNA methylation biomarkers for blood-based colorectal cancer screening. Clin Chem 2008;54:414-23
-
(2008)
Clin Chem
, vol.54
, pp. 414-423
-
-
Lofton-Day, C.1
Model, F.2
Devos, T.3
-
98
-
-
84906229124
-
Detection of colorectal cancer by DNA methylation biomarker SEPT9: past, present and future
-
Li Y, Song L, Gong Y, et al. Detection of colorectal cancer by DNA methylation biomarker SEPT9: past, present and future. Biomark Med 2014;8:755-69
-
(2014)
Biomark Med
, vol.8
, pp. 755-769
-
-
Li, Y.1
Song, L.2
Gong, Y.3
-
99
-
-
84926675759
-
Performance of a second generation methylated SEPT9 test in detecting colorectal neoplasm
-
Jin P, Kang Q, Wang X, et al. Performance of a second generation methylated SEPT9 test in detecting colorectal neoplasm. J Gastroenterol Hepatol 2015;30:830-3
-
(2015)
J Gastroenterol Hepatol
, vol.30
, pp. 830-833
-
-
Jin, P.1
Kang, Q.2
Wang, X.3
-
100
-
-
77955442473
-
From discovery to the clinic: the novel DNA methylation biomarker SEPT9 for the detection of colorectal cancer in blood
-
Payne SR. From discovery to the clinic: the novel DNA methylation biomarker SEPT9 for the detection of colorectal cancer in blood. Epigenomics 2010;2:575-85
-
(2010)
Epigenomics
, vol.2
, pp. 575-585
-
-
Payne, S.R.1
-
101
-
-
84897389147
-
Blood-based testing for colorectal cancer screening
-
Heichman KA. Blood-based testing for colorectal cancer screening. Mol Diagn Ther 2014;18:127-35
-
(2014)
Mol Diagn Ther
, vol.18
, pp. 127-135
-
-
Heichman, K.A.1
-
102
-
-
84898753297
-
A panel of three markers hyper-and hypomethylated in urine sediments accurately predicts bladder cancer recurrence
-
Su SF, de Castro Abreu AL, Chihara Y, et al. A panel of three markers hyper-and hypomethylated in urine sediments accurately predicts bladder cancer recurrence. Clin Cancer Res 2014;20:1978-89
-
(2014)
Clin Cancer Res
, vol.20
, pp. 1978-1989
-
-
Su, S.F.1
de Castro Abreu, A.L.2
Chihara, Y.3
-
103
-
-
84928696411
-
A urine-based methylation signature for risk stratification within low-risk prostate cancer
-
Jatkoe TA, Karnes RJ, Freedland SJ, et al. A urine-based methylation signature for risk stratification within low-risk prostate cancer. Br J Cancer 2015;112:802-8
-
(2015)
Br J Cancer
, vol.112
, pp. 802-808
-
-
Jatkoe, T.A.1
Karnes, R.J.2
Freedland, S.J.3
-
104
-
-
84898902068
-
Novel multiplex MethyLight protocol for detection of DNA methylation in patient tissues and bodily fluids
-
Olkhov-Mitsel E, Zdravic D, Kron K, et al. Novel multiplex MethyLight protocol for detection of DNA methylation in patient tissues and bodily fluids. Sci Rep 2014;4:4432
-
(2014)
Sci Rep
, vol.4
, pp. 4432
-
-
Olkhov-Mitsel, E.1
Zdravic, D.2
Kron, K.3
-
105
-
-
84913593944
-
Prognostic value of RASSF1 promoter methylation in prostate cancer
-
Daniunaite K, Jarmalaite S, Kalinauskaite N, et al. Prognostic value of RASSF1 promoter methylation in prostate cancer. J Urol 2014;192:1849-55
-
(2014)
J Urol
, vol.192
, pp. 1849-1855
-
-
Daniunaite, K.1
Jarmalaite, S.2
Kalinauskaite, N.3
-
107
-
-
49249091385
-
DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight
-
Weisenberger DJ, Trinh BN, Campan M, et al. DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight. Nucleic Acids Res 2008;36:4689-98
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 4689-4698
-
-
Weisenberger, D.J.1
Trinh, B.N.2
Campan, M.3
-
108
-
-
84922021799
-
A comparison of DNA methylation specific droplet digital PCR (ddPCR) and real time qPCR with flow cytometry in characterizing human T cells in peripheral blood
-
Wiencke JK, Bracci PM, Hsuang G, et al. A comparison of DNA methylation specific droplet digital PCR (ddPCR) and real time qPCR with flow cytometry in characterizing human T cells in peripheral blood. Epigenetics 2014;9:1360-5
-
(2014)
Epigenetics
, vol.9
, pp. 1360-1365
-
-
Wiencke, J.K.1
Bracci, P.M.2
Hsuang, G.3
-
109
-
-
82855163962
-
Genome-scale screen for DNA methylation-based detection markers for ovarian cancer
-
Campan M, Moffitt M, Houshdaran S, et al. Genome-scale screen for DNA methylation-based detection markers for ovarian cancer. PloS One 2011;6:e28141
-
(2011)
PloS One
, vol.6
-
-
Campan, M.1
Moffitt, M.2
Houshdaran, S.3
-
110
-
-
84870326702
-
Genome-scale discovery of DNA-methylation biomarkers for blood-based detection of colorectal cancer
-
Lange CP, Campan M, Hinoue T, Slingerland H, et al. Genome-scale discovery of DNA-methylation biomarkers for blood-based detection of colorectal cancer. PloS One 2012;7:e50266
-
(2012)
PloS One
, vol.7
-
-
Lange, C.P.1
Campan, M.2
Hinoue, T.3
Slingerland, H.4
-
111
-
-
0019371789
-
Correlation of Plasma CEA and CEA tissue staining in poorly differentiated colorectal cancer
-
Goslin R, O'Brien MJ, Steele G, et al. Correlation of Plasma CEA and CEA tissue staining in poorly differentiated colorectal cancer. Am J Med 1981;71:246-53
-
(1981)
Am J Med
, vol.71
, pp. 246-253
-
-
Goslin, R.1
O'Brien, M.J.2
Steele, G.3
-
112
-
-
0019428546
-
Immunocytochemical localization of carcinoembryonic antigen in benign and malignant colorectal tissues. Assessment of diagnostic value
-
O'Brien MJ, Zamcheck N, Burke B, et al. Immunocytochemical localization of carcinoembryonic antigen in benign and malignant colorectal tissues. Assessment of diagnostic value. Am J Clin Pathol 1981;75:283-90
-
(1981)
Am J Clin Pathol
, vol.75
, pp. 283-290
-
-
O'Brien, M.J.1
Zamcheck, N.2
Burke, B.3
-
113
-
-
84890313801
-
Chromosomal instability (CIN): what it is and why it is crucial to cancer evolution
-
Heng HH, Bremer SW, Stevens JB, et al. Chromosomal instability (CIN): what it is and why it is crucial to cancer evolution. Cancer Metastasis Rev 2013;32:325-40
-
(2013)
Cancer Metastasis Rev
, vol.32
, pp. 325-340
-
-
Heng, H.H.1
Bremer, S.W.2
Stevens, J.B.3
-
114
-
-
67650376000
-
Genetic and epigenetic heterogeneity in cancer: a genome-centric perspective
-
Heng HH, Bremer SW, Stevens JB, et al. Genetic and epigenetic heterogeneity in cancer: a genome-centric perspective. J Cell Physiol 2009;220:538-47
-
(2009)
J Cell Physiol
, vol.220
, pp. 538-547
-
-
Heng, H.H.1
Bremer, S.W.2
Stevens, J.B.3
-
115
-
-
84890313470
-
Genetic and non-genetic instability in tumor progression: link between the fitness landscape and the epigenetic landscape of cancer cells
-
Huang S. Genetic and non-genetic instability in tumor progression: link between the fitness landscape and the epigenetic landscape of cancer cells. Cancer Metastasis Rev 2013;32:423-48
-
(2013)
Cancer Metastasis Rev
, vol.32
, pp. 423-448
-
-
Huang, S.1
-
116
-
-
7444260846
-
The ENCODE (ENCyclopedia Of DNA Elements) Project
-
ENCODE Project Consortium. The ENCODE (ENCyclopedia Of DNA Elements) Project. Science 2004;306:636-40
-
(2004)
Science
, vol.306
, pp. 636-640
-
-
-
117
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
ENCODE Project Consortium. An integrated encyclopedia of DNA elements in the human genome. Nature 2012;489:57-74
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
-
118
-
-
34250305146
-
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
-
ENCODE Project Consortium, Birney E, Stamatoyannopoulos JA, et al. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 2007;447:799-816
-
(2007)
Nature
, vol.447
, pp. 799-816
-
-
Birney, E.1
Stamatoyannopoulos, J.A.2
-
119
-
-
84889649328
-
Perspectives of international human epigenome consortium
-
Bae JB. Perspectives of international human epigenome consortium. Genomics Inform 2013;11:7-14
-
(2013)
Genomics Inform
, vol.11
, pp. 7-14
-
-
Bae, J.B.1
-
121
-
-
84923362619
-
Integrative analysis of 111 reference human epigenomes
-
Roadmap Epigenomics Consortium, Kundaje A, Meuleman W, et al. Integrative analysis of 111 reference human epigenomes. Nature 2015;518:317-30
-
(2015)
Nature
, vol.518
, pp. 317-330
-
-
Kundaje, A.1
Meuleman, W.2
-
122
-
-
84923343921
-
Presenting the epigenome roadmap
-
Skipper M, Eccleston A, Gray N, et al. Presenting the epigenome roadmap. Nature 2015;518:313
-
(2015)
Nature
, vol.518
, pp. 313
-
-
Skipper, M.1
Eccleston, A.2
Gray, N.3
-
123
-
-
84897022815
-
Comprehensive molecular characterization of urothelial bladder carcinoma
-
The Cancer Genome Atlas Research Network. Comprehensive molecular characterization of urothelial bladder carcinoma. Nature 2014;507:315-22
-
(2014)
Nature
, vol.507
, pp. 315-322
-
-
-
124
-
-
84885074034
-
The somatic genomic landscape of glioblastoma
-
Brennan CW, Verhaak RG, McKenna A, et al. The somatic genomic landscape of glioblastoma. Cell 2013;155:462-77
-
(2013)
Cell
, vol.155
, pp. 462-477
-
-
Brennan, C.W.1
Verhaak, R.G.2
McKenna, A.3
-
125
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
The Cancer Genome Atlas Research Network. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 2008;455:1061-8
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
126
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
Verhaak RG, Hoadley KA, Purdom E, et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 2010;17:98-110
-
(2010)
Cancer Cell
, vol.17
, pp. 98-110
-
-
Verhaak, R.G.1
Hoadley, K.A.2
Purdom, E.3
-
127
-
-
84923197605
-
Comprehensive genomic characterization of head and neck squamous cell carcinomas
-
The Cancer Genome Atlas Research Network. Comprehensive genomic characterization of head and neck squamous cell carcinomas. Nature 2015;517:576-82
-
(2015)
Nature
, vol.517
, pp. 576-582
-
-
-
128
-
-
84908695210
-
The somatic genomic landscape of chromophobe renal cell carcinoma
-
Davis CF, Ricketts CJ, Wang M, et al. The somatic genomic landscape of chromophobe renal cell carcinoma. Cancer Cell 2014;26:319-30
-
(2014)
Cancer Cell
, vol.26
, pp. 319-330
-
-
Davis, C.F.1
Ricketts, C.J.2
Wang, M.3
-
129
-
-
84879890360
-
Comprehensive molecular characterization of clear cell renal cell carcinoma
-
The Cancer Genome Atlas Research Network. Comprehensive molecular characterization of clear cell renal cell carcinoma. Nature 2013;499:43-9
-
(2013)
Nature
, vol.499
, pp. 43-49
-
-
-
130
-
-
84878372012
-
Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
-
The Cancer Genome Atlas Research Network. Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia. N Engl J Med 2013;368:2059-74
-
(2013)
N Engl J Med
, vol.368
, pp. 2059-2074
-
-
-
131
-
-
84905029258
-
Comprehensive molecular profiling of lung adenocarcinoma
-
The Cancer Genome Atlas Research Network. Comprehensive molecular profiling of lung adenocarcinoma. Nature 2014;511:543-50
-
(2014)
Nature
, vol.511
, pp. 543-550
-
-
-
132
-
-
84866894408
-
Comprehensive genomic characterization of squamous cell lung cancers
-
The Cancer Genome Atlas Research Network. Comprehensive genomic characterization of squamous cell lung cancers. Nature 2012;489:519-25
-
(2012)
Nature
, vol.489
, pp. 519-525
-
-
-
133
-
-
84907270779
-
Comprehensive molecular characterization of gastric adenocarcinoma
-
The Cancer Genome Atlas Research Network. Comprehensive molecular characterization of gastric adenocarcinoma. Nature 2014;513:202-9
-
(2014)
Nature
, vol.513
, pp. 202-209
-
-
-
134
-
-
84908335908
-
Integrated genomic characterization of papillary thyroid carcinoma
-
The Cancer Genome Atlas Research Network. Integrated genomic characterization of papillary thyroid carcinoma. Cell 2014;159:676-90
-
(2014)
Cell
, vol.159
, pp. 676-690
-
-
-
135
-
-
84877254190
-
Integrated genomic characterization of endometrial carcinoma
-
The Cancer Genome Atlas Research Network, Kandoth C, Schultz N, et al. Integrated genomic characterization of endometrial carcinoma. Nature 2013;497:67-73
-
(2013)
Nature
, vol.497
, pp. 67-73
-
-
Kandoth, C.1
Schultz, N.2
-
136
-
-
84908460595
-
Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin
-
Hoadley KA, Yau C, Wolf DM, et al. Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin. Cell 2014;158:929-44
-
(2014)
Cell
, vol.158
, pp. 929-944
-
-
Hoadley, K.A.1
Yau, C.2
Wolf, D.M.3
-
137
-
-
84892920228
-
Characterizing DNA methylation alterations from The Cancer Genome Atlas
-
Weisenberger DJ. Characterizing DNA methylation alterations from The Cancer Genome Atlas. J Clin Invest 2014;124:17-23
-
(2014)
J Clin Invest
, vol.124
, pp. 17-23
-
-
Weisenberger, D.J.1
-
138
-
-
84884994218
-
The Cancer Genome Atlas Pan-Cancer analysis project
-
The Cancer Genome Atlas Research Network, Weinstein JN, Collisson EA, et al. The Cancer Genome Atlas Pan-Cancer analysis project. Nat Genet 2013;45:1113-20
-
(2013)
Nat Genet
, vol.45
, pp. 1113-1120
-
-
Weinstein, J.N.1
Collisson, E.A.2
-
140
-
-
77249141762
-
Analysis of the association between CIMP and BRAF in colorectal cancer by DNA methylation profiling
-
Hinoue T, Weisenberger DJ, Pan F, et al. Analysis of the association between CIMP and BRAF in colorectal cancer by DNA methylation profiling. PloS One 2009;4:e8357
-
(2009)
PloS One
, vol.4
-
-
Hinoue, T.1
Weisenberger, D.J.2
Pan, F.3
-
141
-
-
58249089525
-
CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer
-
Ogino S, Nosho K, Kirkner GJ, et al. CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer. Gut 2009;58:90-6
-
(2009)
Gut
, vol.58
, pp. 90-96
-
-
Ogino, S.1
Nosho, K.2
Kirkner, G.J.3
-
142
-
-
84922879141
-
Association between molecular subtypes of colorectal cancer and patient survival
-
Phipps AI, Limburg PJ, Baron JA, et al. Association between molecular subtypes of colorectal cancer and patient survival. Gastroenterology 2015;148:77-87.e2
-
(2015)
Gastroenterology
, vol.148
, pp. 77-87
-
-
Phipps, A.I.1
Limburg, P.J.2
Baron, J.A.3
-
143
-
-
33745541234
-
CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer
-
Weisenberger DJ, Siegmund KD, Campan M, et al. CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer. Nat Genet 2006;38:787-93
-
(2006)
Nat Genet
, vol.38
, pp. 787-793
-
-
Weisenberger, D.J.1
Siegmund, K.D.2
Campan, M.3
-
144
-
-
84927764153
-
Association of the colorectal CpG island methylator phenotype with molecular features, risk factors, and family history
-
Weisenberger DJ, Levine AJ, Long TI, et al. Association of the colorectal CpG island methylator phenotype with molecular features, risk factors, and family history. Cancer Epidemiol Biomarkers Prev 2015;24:512-9
-
(2015)
Cancer Epidemiol Biomarkers Prev
, vol.24
, pp. 512-519
-
-
Weisenberger, D.J.1
Levine, A.J.2
Long, T.I.3
-
145
-
-
33749069927
-
CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: possible associations with male sex and KRAS mutations
-
Ogino S, Kawasaki T, Kirkner GJ, et al. CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: possible associations with male sex and KRAS mutations. J Mol Diagn 2006;8:582-8
-
(2006)
J Mol Diagn
, vol.8
, pp. 582-588
-
-
Ogino, S.1
Kawasaki, T.2
Kirkner, G.J.3
-
146
-
-
36749025213
-
Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer
-
Shen L, Toyota M, Kondo Y, et al. Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer. Proc Natl Acad Sci U S A 2007;104:18654-9
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 18654-18659
-
-
Shen, L.1
Toyota, M.2
Kondo, Y.3
-
149
-
-
0037068379
-
5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy
-
Christman JK. 5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy. Oncogene 2002;21:5483-95
-
(2002)
Oncogene
, vol.21
, pp. 5483-5495
-
-
Christman, J.K.1
-
150
-
-
0037420191
-
Inhibition of DNA methylation and reactivation of silenced genes by zebularine
-
Cheng JC, Matsen CB, Gonzales FA, et al. Inhibition of DNA methylation and reactivation of silenced genes by zebularine. J Natl Cancer Inst 2003;95:399-409
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 399-409
-
-
Cheng, J.C.1
Matsen, C.B.2
Gonzales, F.A.3
-
151
-
-
5144228492
-
Preferential response of cancer cells to zebularine
-
Cheng JC, Yoo CB, Weisenberger DJ, et al. Preferential response of cancer cells to zebularine. Cancer Cell 2004;6:151-8
-
(2004)
Cancer Cell
, vol.6
, pp. 151-158
-
-
Cheng, J.C.1
Yoo, C.B.2
Weisenberger, D.J.3
-
152
-
-
79952377463
-
Resistance, epigenetics and the cancer ecosystem
-
Baylin SB. Resistance, epigenetics and the cancer ecosystem. Nat Med 2011;17:288-9
-
(2011)
Nat Med
, vol.17
, pp. 288-289
-
-
Baylin, S.B.1
-
153
-
-
84890130945
-
Alterations of immune response of Non-Small Cell Lung Cancer with Azacytidine
-
Wrangle J, Wang W, Koch A, et al. Alterations of immune response of Non-Small Cell Lung Cancer with Azacytidine. Oncotarget 2013;4:2067-79
-
(2013)
Oncotarget
, vol.4
, pp. 2067-2079
-
-
Wrangle, J.1
Wang, W.2
Koch, A.3
-
154
-
-
84892949427
-
Harnessing the potential of epigenetic therapy to target solid tumors
-
Ahuja N, Easwaran H, Baylin SB. Harnessing the potential of epigenetic therapy to target solid tumors. J Clin Invest 2014;124:56-63
-
(2014)
J Clin Invest
, vol.124
, pp. 56-63
-
-
Ahuja, N.1
Easwaran, H.2
Baylin, S.B.3
-
155
-
-
84655163371
-
Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer
-
Juergens RA, Wrangle J, Vendetti FP, et al. Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer. Cancer Discov 2011;1:598-607
-
(2011)
Cancer Discov
, vol.1
, pp. 598-607
-
-
Juergens, R.A.1
Wrangle, J.2
Vendetti, F.P.3
-
156
-
-
77952203695
-
S110, a 5-Aza-2'-deoxycytidine-containing dinucleotide, is an effective DNA methylation inhibitor in vivo and can reduce tumor growth
-
Chuang JC, Warner SL, Vollmer D, et al. S110, a 5-Aza-2'-deoxycytidine-containing dinucleotide, is an effective DNA methylation inhibitor in vivo and can reduce tumor growth. Mol Cancer Ther 2010;9:1443-50
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 1443-1450
-
-
Chuang, J.C.1
Warner, S.L.2
Vollmer, D.3
-
157
-
-
34447123203
-
Delivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides
-
Yoo CB, Jeong S, Egger G, et al. Delivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides. Cancer Res 2007;67:6400-8
-
(2007)
Cancer Res
, vol.67
, pp. 6400-6408
-
-
Yoo, C.B.1
Jeong, S.2
Egger, G.3
|