Chromosomal instability (CIN): What it is and why it is crucial to cancer evolution

Cancer and Metastasis Reviews

Volumn 32, Issue 3-4, 2013, Pages 325-340

  Heng, Henry H ^a   Bremer, Steven W ^a   Stevens, Joshua B ^a   Horne, Steven D ^a   Liu, Guo ^a   Abdallah, Batoul Y ^a   Ye, Karen J ^b   Ye, Christine J ^c  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SeeDNA Biotech Inc   (Canada)

^c KARMANOS CANCER INSTITUTE   (United States)

Author keywords

Chromosomal instability (CIN); Evolutionary mechanism of cancer (EMC); Genome chaos; Genome heterogeneity; Genome instability; Genome theory; Nonclonal chromosome aberrations (NCCAs); System inheritance

Indexed keywords

ARTICLE; CANCER GROWTH; CARCINOGENESIS; CHROMOSOMAL INSTABILITY; CHROMOSOME ABERRATION; EPIGENETICS; GENE MUTATION; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENOME; HUMAN; KARYOTYPE; MOLECULAR BIOLOGY; NONHUMAN; PRIORITY JOURNAL; PROGNOSIS; STRESS;

ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; CHROMOSOMAL INSTABILITY; HUMANS; NEOPLASMS; RESEARCH;

EID: 84890313801     PISSN: 01677659     EISSN: 15737233     Source Type: Journal    
DOI: 10.1007/s10555-013-9427-7     Document Type: Article

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