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Volumn 17, Issue 5, 2016, Pages 272-283

Endogenous microRNA sponges: Evidence and controversy

Author keywords

[No Author keywords available]

Indexed keywords

ANTAGOMIR; ANTISENSE OLIGONUCLEOTIDE; COMPETITIVE ENDOGENOUS RNA; MESSENGER RNA; MICRORNA; RNA; SMALL NUCLEAR RNA; UNCLASSIFIED DRUG; LONG UNTRANSLATED RNA; TRANSCRIPTOME;

EID: 84962086887     PISSN: 14710056     EISSN: 14710064     Source Type: Journal    
DOI: 10.1038/nrg.2016.20     Document Type: Article
Times cited : (1708)

References (146)
  • 1
    • 84946013175 scopus 로고    scopus 로고
    • LncRNAdb v2.0: Expanding the reference database for functional long noncoding RNAs
    • Quek X. C, et al. lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs. Nucleic Acids Res. 43, D168-D173 (2015).
    • (2015) Nucleic Acids Res , vol.43 , pp. D168-D173
    • Quek, X.C.1
  • 2
    • 79961170994 scopus 로고    scopus 로고
    • A ceRNA hypo thesis the Rosetta Stone of a hidden RNA language?
    • Salmena L, Poliseno L, Tay Y, Kats L, & Pandolfi P. P A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language?. Cell. 146, 353-358 (2011).
    • (2011) Cell , vol.146 , pp. 353-358
    • Salmena, L.1    Poliseno, L.2    Tay, Y.3    Kats, L.4    Pandolfi, P.P.5
  • 3
    • 84901820446 scopus 로고    scopus 로고
    • Competitive endogenous RNAs cannot alter microRNA function in vivo
    • Broderick J. A, & Zamore P. D. Competitive endogenous RNAs cannot alter microRNA function in vivo. Mol. Cell. 54, 711-713 (2014).
    • (2014) Mol. Cell , vol.54 , pp. 711-713
    • Broderick, J.A.1    Zamore, P.D.2
  • 4
    • 84901838697 scopus 로고    scopus 로고
    • Assessing the ceRNA hypothesis with quantitative measurements of miRNA and target abundance
    • Denzler R, Agarwal V, Stefano J, Bartel D. P, & Stoffel M. Assessing the ceRNA hypothesis with quantitative measurements of miRNA and target abundance. Mol. Cell. 54, 766-776 (2014).
    • (2014) Mol. Cell , vol.54 , pp. 766-776
    • Denzler, R.1    Agarwal, V.2    Stefano, J.3    Bartel, D.P.4    Stoffel, M.5
  • 5
    • 84922418997 scopus 로고    scopus 로고
    • Endogenous miRNA and target concentrations determine susceptibility to potential ceRNA competition
    • Bosson A. D, Zamudio J. R, & Sharp P. A. Endogenous miRNA and target concentrations determine susceptibility to potential ceRNA competition. Mol. Cell. 56, 347-359 (2014).
    • (2014) Mol. Cell , vol.56 , pp. 347-359
    • Bosson, A.D.1    Zamudio, J.R.2    Sharp, P.A.3
  • 6
    • 84924330592 scopus 로고    scopus 로고
    • Competition between target sites of regulators shapes post-Transcriptional gene regulation
    • Jens M, & Rajewsky N. Competition between target sites of regulators shapes post-Transcriptional gene regulation. Nat. Rev. Genet. 16, 113-126 (2015).
    • (2015) Nat. Rev. Genet , vol.16 , pp. 113-126
    • Jens, M.1    Rajewsky, N.2
  • 7
    • 84876899530 scopus 로고    scopus 로고
    • Integrated transcriptional and competitive endogenous RNA networks are cross-regulated in permissive molecular environments
    • Ala U, et al. Integrated transcriptional and competitive endogenous RNA networks are cross-regulated in permissive molecular environments. Proc. Natl Acad. Sci. USA. 110, 7154-7159 (2013).
    • (2013) Proc. Natl Acad. Sci. USA , vol.110 , pp. 7154-7159
    • Ala, U.1
  • 8
    • 84879486402 scopus 로고    scopus 로고
    • Modelling competing endogenous RNA networks
    • Bosia C, Pagnani A, & Zecchina R. Modelling competing endogenous RNA networks. PLoS ONE. 8, e66609 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e66609
    • Bosia, C.1    Pagnani, A.2    Zecchina, R.3
  • 9
    • 84874833554 scopus 로고    scopus 로고
    • MicroRNAs as a selective channel of communication between competing RNAs: A steady-state theory
    • Figliuzzi M, Marinari E, & De Martino A. MicroRNAs as a selective channel of communication between competing RNAs: a steady-state theory. Biophys. J. 104, 1203-1213 (2013).
    • (2013) Biophys. J. , vol.104 , pp. 1203-1213
    • Figliuzzi, M.1    Marinari, E.2    De Martino, A.3
  • 10
    • 84924302007 scopus 로고    scopus 로고
    • Model-guided quantitative analysis of microRNA-mediated regulation on competing endogenous RNAs using a synthetic gene circuit
    • Yuan Y, et al. Model-guided quantitative analysis of microRNA-mediated regulation on competing endogenous RNAs using a synthetic gene circuit. Proc. Natl Acad. Sci. USA. 112, 3158-3163 (2015).
    • (2015) Proc. Natl Acad. Sci. USA , vol.112 , pp. 3158-3163
    • Yuan, Y.1
  • 11
    • 84893698705 scopus 로고    scopus 로고
    • Competing endogenous RNAs (ceRNAs): New entrants to the intricacies of gene regulation
    • Kartha R. V, & Subramanian S. Competing endogenous RNAs (ceRNAs): new entrants to the intricacies of gene regulation. Front. Genet. 5, 8 (2014).
    • (2014) Front. Genet , vol.5 , pp. 8
    • Kartha, R.V.1    Subramanian, S.2
  • 12
    • 84891818924 scopus 로고    scopus 로고
    • StarBase v2.0: Decoding miRNA-ceRNA, miRNA-ncRNA and protein-RNA interaction networks from large-scale CLIP-Seq data
    • Li J. H, Liu S, Zhou H, Qu L. H, & Yang J. H. starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein-RNA interaction networks from large-scale CLIP-Seq data. Nucleic Acids Res. 42, D92-D97 (2014).
    • (2014) Nucleic Acids Res , vol.42 , pp. D92-D97
    • Li, J.H.1    Liu, S.2    Zhou, H.3    Qu, L.H.4    Yang, J.H.5
  • 13
    • 84876167066 scopus 로고    scopus 로고
    • Competing endogenous RNA database
    • Sarver A. L, & Subramanian S. Competing endogenous RNA database. Bioinformation. 8, 731-733 (2012).
    • (2012) Bioinformation , vol.8 , pp. 731-733
    • Sarver, A.L.1    Subramanian, S.2
  • 14
    • 84903136092 scopus 로고    scopus 로고
    • LnCeDB: Database of human long noncoding RNA acting as competing endogenous RNA
    • Das S, Ghosal S, Sen R, & Chakrabarti J. lnCeDB: database of human long noncoding RNA acting as competing endogenous RNA. PLoS ONE. 9, e98965 (2014).
    • (2014) PLoS ONE , vol.9 , pp. e98965
    • Das, S.1    Ghosal, S.2    Sen, R.3    Chakrabarti, J.4
  • 15
    • 84922372948 scopus 로고    scopus 로고
    • Cupid: Simultaneous reconstruction of microRNA-Target and ceRNA networks
    • Chiu H. S, et al. Cupid: simultaneous reconstruction of microRNA-Target and ceRNA networks. Genome Res. 25, 257-267 (2015).
    • (2015) Genome Res , vol.25 , pp. 257-267
    • Chiu, H.S.1
  • 16
    • 84964312596 scopus 로고    scopus 로고
    • Systematic exploration of autonomous modules in noisy microRNA-Target networks for testing the generality of the ceRNA hypothesis
    • Yip D. K, Pang I. K, & Yip K. Y. Systematic exploration of autonomous modules in noisy microRNA-Target networks for testing the generality of the ceRNA hypothesis. BMC Genomics. 15, 1178 (2014).
    • (2014) BMC Genomics , vol.15 , pp. 1178
    • Yip, D.K.1    Pang, I.K.2    Yip, K.Y.3
  • 17
    • 84943192833 scopus 로고    scopus 로고
    • MiRSponge: A manually curated database for experimentally supported miRNA sponges and ceRNAs
    • bav098
    • Wang P, et al. miRSponge: a manually curated database for experimentally supported miRNA sponges and ceRNAs. Database (Oxford) 2015, bav098 (2015).
    • (2015) Database (Oxford , vol.2015
    • Wang, P.1
  • 18
    • 84925515962 scopus 로고    scopus 로고
    • Competing endogenous RNA interplay in cancer: Mechanism, methodology, and perspectives
    • Cheng D. L, Xiang Y. Y, Ji L. J, & Lu X. J. Competing endogenous RNA interplay in cancer: mechanism, methodology, and perspectives. Tumour Biol. 36, 479-488 (2015).
    • (2015) Tumour Biol , vol.36 , pp. 479-488
    • Cheng, D.L.1    Xiang, Y.Y.2    Ji, L.J.3    Lu, X.J.4
  • 19
    • 84907344020 scopus 로고    scopus 로고
    • RNA-based regulation: Dynamics and response to perturbations of competing RNAs
    • Figliuzzi M, De Martino A, & Marinari E. RNA-based regulation: dynamics and response to perturbations of competing RNAs. Biophys. J. 107, 1011-1022 (2014).
    • (2014) Biophys. J. , vol.107 , pp. 1011-1022
    • Figliuzzi, M.1    De Martino, A.2    Marinari, E.3
  • 20
    • 84930505376 scopus 로고    scopus 로고
    • Identification of lncRNA-Associated competing triplets reveals global patterns and prognostic markers for cancer
    • Wang P, et al. Identification of lncRNA-Associated competing triplets reveals global patterns and prognostic markers for cancer. Nucleic Acids Res. 43, 3478-3489 (2015).
    • (2015) Nucleic Acids Res , vol.43 , pp. 3478-3489
    • Wang, P.1
  • 21
    • 84904272774 scopus 로고    scopus 로고
    • Computational analysis identifies a sponge interaction network between long non-coding RNAs and messenger RNAs in human breast cancer
    • Paci P, Colombo T, & Farina L. Computational analysis identifies a sponge interaction network between long non-coding RNAs and messenger RNAs in human breast cancer. BMC Syst. Biol. 8, 83 (2014).
    • (2014) BMC Syst. Biol , vol.8 , pp. 83
    • Paci, P.1    Colombo, T.2    Farina, L.3
  • 22
    • 84864448111 scopus 로고    scopus 로고
    • High-Throughput assessment of microRNA activity and function using microRNA sensor and decoy libraries
    • Mullokandov G, et al. High-Throughput assessment of microRNA activity and function using microRNA sensor and decoy libraries. Nat. Methods. 9, 840-846 (2012).
    • (2012) Nat. Methods , vol.9 , pp. 840-846
    • Mullokandov, G.1
  • 23
    • 1242318826 scopus 로고    scopus 로고
    • Sequence-specific inhibition of microRNA- And siRNA-induced RNA silencing
    • Meister G, Landthaler M, Dorsett Y, & Tuschl T. Sequence-specific inhibition of microRNA- And siRNA-induced RNA silencing. RNA. 10, 544-550 (2004).
    • (2004) RNA , vol.10 , pp. 544-550
    • Meister, G.1    Landthaler, M.2    Dorsett, Y.3    Tuschl, T.4
  • 24
    • 28444469246 scopus 로고    scopus 로고
    • Silencing of microRNAs in vivo with ?antagomirs
    • Krutzfeldt J, et al. Silencing of microRNAs in vivo with ?antagomirs. Nature. 438, 685-689 (2005).
    • (2005) Nature , vol.438 , pp. 685-689
    • Krutzfeldt, J.1
  • 25
    • 33646027887 scopus 로고    scopus 로고
    • LNA-modified oligonucleotides mediate specific inhibition of microRNA function
    • Orom U. A, Kauppinen S, & Lund A. H. LNA-modified oligonucleotides mediate specific inhibition of microRNA function. Gene. 372, 137-141 (2006).
    • (2006) Gene , vol.372 , pp. 137-141
    • Orom, U.A.1    Kauppinen, S.2    Lund, A.H.3
  • 26
    • 36849060584 scopus 로고    scopus 로고
    • Endogenous microRNA can be broadly exploited to regulate transgene expression according to tissue, lineage and differentiation state
    • Brown B. D, et al. Endogenous microRNA can be broadly exploited to regulate transgene expression according to tissue, lineage and differentiation state. Nat. Biotechnol. 25, 1457-1467 (2007).
    • (2007) Nat. Biotechnol , vol.25 , pp. 1457-1467
    • Brown, B.D.1
  • 27
    • 34249279050 scopus 로고    scopus 로고
    • MicroRNA 133 controls cardiac hypertrophy
    • Care A, et al. MicroRNA 133 controls cardiac hypertrophy. Nat. Med. 13, 613-618 (2007).
    • (2007) Nat. Med , vol.13 , pp. 613-618
    • Care, A.1
  • 28
    • 34548316982 scopus 로고    scopus 로고
    • MicroRNA sponges: Competitive inhibitors of small RNAs in mammalian cells
    • Ebert M. S, Neilson J. R, & Sharp P. A. MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nat. Methods. 4, 721-726 (2007).
    • (2007) Nat. Methods , vol.4 , pp. 721-726
    • Ebert, M.S.1    Neilson, J.R.2    Sharp, P.A.3
  • 29
    • 84908395519 scopus 로고    scopus 로고
    • Antisense therapeutics in oncology: Current status
    • Farooqi A. A, Rehman Z. U, & Muntane J. Antisense therapeutics in oncology: current status. Onco. Targets Ther. 7, 2035-2042 (2014).
    • (2014) Onco. Targets Ther , vol.7 , pp. 2035-2042
    • Farooqi, A.A.1    Rehman, Z.U.2    Muntane, J.3
  • 30
    • 78149303249 scopus 로고    scopus 로고
    • MicroRNA sponges: Progress and possibilities
    • Ebert M. S, & Sharp P. A. MicroRNA sponges: progress and possibilities. RNA. 16, 2043-2050 (2010).
    • (2010) RNA , vol.16 , pp. 2043-2050
    • Ebert, M.S.1    Sharp, P.A.2
  • 31
    • 42249093319 scopus 로고    scopus 로고
    • LNA-mediated microRNA silencing in non-human primates
    • Elmen J, et al. LNA-mediated microRNA silencing in non-human primates. Nature. 452, 896-899 (2008).
    • (2008) Nature , vol.452 , pp. 896-899
    • Elmen, J.1
  • 32
    • 64549109671 scopus 로고    scopus 로고
    • Vectors expressing efficient RNA decoys achieve the long-Term suppression of specific microRNA activity in mammalian cells
    • Haraguchi T, Ozaki Y, & Iba H. Vectors expressing efficient RNA decoys achieve the long-Term suppression of specific microRNA activity in mammalian cells. Nucleic Acids Res. 37, e43 (2009).
    • (2009) Nucleic Acids Res , vol.37 , pp. e43
    • Haraguchi, T.1    Ozaki, Y.2    Iba, H.3
  • 33
    • 84860720576 scopus 로고    scopus 로고
    • Polymer nanoparticle-mediated delivery of microRNA inhibition and alternative splicing
    • Cheng C. J, & Saltzman W. M. Polymer nanoparticle-mediated delivery of microRNA inhibition and alternative splicing. Mol. Pharm. 9, 1481-1488 (2012).
    • (2012) Mol. Pharm , vol.9 , pp. 1481-1488
    • Cheng, C.J.1    Saltzman, W.M.2
  • 34
    • 77957850291 scopus 로고    scopus 로고
    • Emerging roles for natural microRNA sponges
    • Ebert M. S, & Sharp P. A. Emerging roles for natural microRNA sponges. Curr. Biol. 20, R858-R861 (2010).
    • (2010) Curr. Biol , vol.20 , pp. R858-R861
    • Ebert, M.S.1    Sharp, P.A.2
  • 35
    • 33646715590 scopus 로고    scopus 로고
    • Improved targeting of miRNA with antisense oligonucleotides
    • Davis S, Lollo B, Freier S, & Esau C. Improved targeting of miRNA with antisense oligonucleotides. Nucleic Acids Res. 34, 2294-2304 (2006).
    • (2006) Nucleic Acids Res , vol.34 , pp. 2294-2304
    • Davis, S.1    Lollo, B.2    Freier, S.3    Esau, C.4
  • 36
    • 84872864743 scopus 로고    scopus 로고
    • On measuring miRNAs after transient transfection of mimics or antisense inhibitors
    • Thomson D. W, Bracken C. P, Szubert J. M, & Goodall G. J. On measuring miRNAs after transient transfection of mimics or antisense inhibitors. PLoS ONE. 8, e55214 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e55214
    • Thomson, D.W.1    Bracken, C.P.2    Szubert, J.M.3    Goodall, G.J.4
  • 37
    • 84922773672 scopus 로고    scopus 로고
    • Modulation of lipoprotein metabolism by antisense technology: Preclinical drug discovery methodology
    • Crooke R. M, & Graham M. J. Modulation of lipoprotein metabolism by antisense technology: preclinical drug discovery methodology. Methods Mol. Biol. 1027, 309-324 (2013).
    • (2013) Methods Mol. Biol , vol.1027 , pp. 309-324
    • Crooke, R.M.1    Graham, M.J.2
  • 38
    • 37349113774 scopus 로고    scopus 로고
    • Inhibition of microRNA with antisense oligonucleotides
    • Esau C. C. Inhibition of microRNA with antisense oligonucleotides. Methods. 44, 55-60 (2008).
    • (2008) Methods , vol.44 , pp. 55-60
    • Esau, C.C.1
  • 39
    • 84875372911 scopus 로고    scopus 로고
    • Natural RNA circles function as efficient microRNA sponges
    • Hansen T. B, et al. Natural RNA circles function as efficient microRNA sponges. Nature. 495, 384-388 (2013).
    • (2013) Nature , vol.495 , pp. 384-388
    • Hansen, T.B.1
  • 40
    • 84875369248 scopus 로고    scopus 로고
    • Circular RNAs are a large class of animal RNAs with regulatory potency
    • Memczak S, et al. Circular RNAs are a large class of animal RNAs with regulatory potency. Nature. 495, 333-338 (2013).
    • (2013) Nature , vol.495 , pp. 333-338
    • Memczak, S.1
  • 41
    • 84881503516 scopus 로고    scopus 로고
    • Pseudogene OCT4 pg4 functions as a natural micro RNA sponge to regulate OCT4 expression by competing for MIR 145 in hepatocellular carcinoma
    • Wang L, et al. Pseudogene OCT4 pg4 functions as a natural micro RNA sponge to regulate OCT4 expression by competing for miR 145 in hepatocellular carcinoma. Carcinogenesis. 34, 1773-1781 (2013).
    • (2013) Carcinogenesis , vol.34 , pp. 1773-1781
    • Wang, L.1
  • 42
    • 84868676906 scopus 로고    scopus 로고
    • Evidence for conserved post-Transcriptional roles of unitary pseudogenes and for frequent bifunctionality of mRNAs
    • Marques A. C, et al. Evidence for conserved post-Transcriptional roles of unitary pseudogenes and for frequent bifunctionality of mRNAs. Genome Biol. 13, R102 (2012).
    • (2012) Genome Biol , vol.13 , pp. R102
    • Marques, A.C.1
  • 43
    • 77953957633 scopus 로고    scopus 로고
    • A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
    • Poliseno L, et al A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature. 465, 1033-1038 (2010).
    • (2010) Nature , vol.465 , pp. 1033-1038
    • Poliseno, L.1
  • 44
    • 84876177255 scopus 로고    scopus 로고
    • A pseudogene long-noncoding-RNA network regulates PTEN transcription and translation in human cells
    • Johnsson P, et al A pseudogene long-noncoding-RNA network regulates PTEN transcription and translation in human cells. Nat. Struct. Mol. Biol. 20, 440-446 (2013).
    • (2013) Nat. Struct. Mol. Biol , vol.20 , pp. 440-446
    • Johnsson, P.1
  • 45
    • 84918545890 scopus 로고    scopus 로고
    • Pseudogene PTENP1 functions as a competing endogenous RNA to suppress clear-cell renal cell carcinoma progression
    • Yu G, et al. Pseudogene PTENP1 functions as a competing endogenous RNA to suppress clear-cell renal cell carcinoma progression. Mol. Cancer Ther. 13, 3086-3097 (2014).
    • (2014) Mol. Cancer Ther , vol.13 , pp. 3086-3097
    • Yu, G.1
  • 46
    • 84925499111 scopus 로고    scopus 로고
    • The 3'UTR of the pseudogene CYP4Z2P promotes tumor angiogenesis in breast cancer by acting as a ceRNA for CYP4Z1
    • Zheng L, Li X, Gu Y, Lv X, & Xi T. The 3'UTR of the pseudogene CYP4Z2P promotes tumor angiogenesis in breast cancer by acting as a ceRNA for CYP4Z1. Breast Cancer Res. Treat. 150, 105-118 (2015).
    • (2015) Breast Cancer Res. Treat , vol.150 , pp. 105-118
    • Zheng, L.1    Li, X.2    Gu, Y.3    Lv, X.4    Xi, T.5
  • 47
    • 34547497309 scopus 로고    scopus 로고
    • Target mimicry provides a new mechanism for regulation of microRNA activity
    • Franco-Zorrilla J. M, et al. Target mimicry provides a new mechanism for regulation of microRNA activity. Nat. Genet. 39, 1033-1037 (2007).
    • (2007) Nat. Genet , vol.39 , pp. 1033-1037
    • Franco-Zorrilla, J.M.1
  • 48
    • 77956542998 scopus 로고    scopus 로고
    • CREB up regulates long non-coding RNA HULC expression through interaction with microRNA 372 in liver cancer
    • Wang J, et al. CREB up regulates long non-coding RNA, HULC expression through interaction with microRNA 372 in liver cancer. Nucleic Acids Res. 38, 5366-5383 (2010).
    • (2010) Nucleic Acids Res , vol.38 , pp. 5366-5383
    • Wang, J.1
  • 49
    • 84877270735 scopus 로고    scopus 로고
    • LncRNA loc285194 is a p53 regulated tumor suppressor
    • Liu Q, et al. LncRNA loc285194 is a p53 regulated tumor suppressor. Nucleic Acids Res. 41, 4976-4987 (2013).
    • (2013) Nucleic Acids Res , vol.41 , pp. 4976-4987
    • Liu, Q.1
  • 50
    • 84876367541 scopus 로고    scopus 로고
    • Endogenous miRNA sponge lincRNA-RoR regulates Oct4 Nanog, and Sox2 in human embryonic stem cell self-renewal
    • Wang Y, et al. Endogenous miRNA sponge lincRNA-RoR regulates Oct4, Nanog, and Sox2 in human embryonic stem cell self-renewal. Dev. Cell. 25, 69-80 (2013).
    • (2013) Dev. Cell , vol.25 , pp. 69-80
    • Wang, Y.1
  • 51
    • 80054715378 scopus 로고    scopus 로고
    • A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA
    • Cesana M, et al A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA. Cell. 147, 358-369 (2011).
    • (2011) Cell , vol.147 , pp. 358-369
    • Cesana, M.1
  • 52
    • 84874634893 scopus 로고    scopus 로고
    • A long non-coding RNA, PTCSC3, as a tumor suppressor and a target of miRNAs in thyroid cancer cells
    • Fan M, et al A long non-coding RNA, PTCSC3, as a tumor suppressor and a target of miRNAs in thyroid cancer cells. Exp. Ther. Med. 5, 1143-1146 (2013).
    • (2013) Exp. Ther. Med , vol.5 , pp. 1143-1146
    • Fan, M.1
  • 53
    • 84874583945 scopus 로고    scopus 로고
    • Versican 3' untranslated region (3' UTR) functions as a ceRNA in inducing the development of hepatocellular carcinoma by regulating miRNA activity
    • Fang L, et al. Versican 3' untranslated region (3' UTR) functions as a ceRNA in inducing the development of hepatocellular carcinoma by regulating miRNA activity. FASEB J. 27, 907-919 (2013).
    • (2013) FASEB J. , vol.27 , pp. 907-919
    • Fang, L.1
  • 54
    • 84946486481 scopus 로고    scopus 로고
    • CXCR4 3'UTR functions as a ceRNA in promoting metastasis, proliferation and survival of MCF 7 cells by regulating MIR 146a activity
    • Zheng T, et al. CXCR4 3'UTR functions as a ceRNA in promoting metastasis, proliferation and survival of MCF 7 cells by regulating miR 146a activity. Eur. J. Cell Biol. 458-469 (2015).
    • (2015) Eur. J. Cell Biol , pp. 458-469
    • Zheng, T.1
  • 55
    • 77953798171 scopus 로고    scopus 로고
    • Down-regulation of a host microRNA by a Herpesvirus saimiri noncoding RNA
    • Cazalla D, Yario T, & Steitz J. A. Down-regulation of a host microRNA by a Herpesvirus saimiri noncoding RNA. Science. 328, 1563-1566 (2010).
    • (2010) Science , vol.328 , pp. 1563-1566
    • Cazalla, D.1    Yario, T.2    Steitz, J.A.3
  • 56
    • 84879126123 scopus 로고    scopus 로고
    • Selective degradation of host MicroRNAs by an intergenic HCMV noncoding RNA accelerates virus production
    • Lee S, et al. Selective degradation of host MicroRNAs by an intergenic HCMV noncoding RNA accelerates virus production. Cell Host Microbe. 13, 678-690 (2013).
    • (2013) Cell Host Microbe , vol.13 , pp. 678-690
    • Lee, S.1
  • 57
    • 84924561760 scopus 로고    scopus 로고
    • Hepatitis C virus RNA functionally sequesters MIR 122
    • Luna J. M, et al. Hepatitis C virus RNA functionally sequesters miR 122. Cell. 160, 1099-1110 (2015).
    • (2015) Cell , vol.160 , pp. 1099-1110
    • Luna, J.M.1
  • 58
    • 80052978224 scopus 로고    scopus 로고
    • Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses
    • Cabili M. N, et al. Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses. Genes Dev. 25, 1915-1927 (2011).
    • (2011) Genes Dev , vol.25 , pp. 1915-1927
    • Cabili, M.N.1
  • 59
    • 84865727393 scopus 로고    scopus 로고
    • The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression
    • Derrien T, et al. The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. Genome Res. 22, 1775-1789 (2012).
    • (2012) Genome Res , vol.22 , pp. 1775-1789
    • Derrien, T.1
  • 60
    • 80053523254 scopus 로고    scopus 로고
    • The evolution of RNAs with multiple functions
    • Dinger M. E, Gascoigne D. K, & Mattick J. S. The evolution of RNAs with multiple functions. Biochimie. 93, 2013-2018 (2011).
    • (2011) Biochimie , vol.93 , pp. 2013-2018
    • Dinger, M.E.1    Gascoigne, D.K.2    Mattick, J.S.3
  • 61
    • 84954315702 scopus 로고    scopus 로고
    • IGF1 3UTR functions as a ceRNA in promoting angiogenesis by sponging MIR-29 family in osteosarcoma
    • Gao S, et al. IGF1 3UTR functions as a ceRNA in promoting angiogenesis by sponging miR-29 family in osteosarcoma. J. Mol. Histol. 47, 135-143 (2016).
    • (2016) J. Mol. Histol , vol.47 , pp. 135-143
    • Gao, S.1
  • 62
    • 79955598536 scopus 로고    scopus 로고
    • Expression of CD44 3' untranslated region regulates endogenous microRNA functions in tumorigenesis and angiogenesis
    • Jeyapalan Z, et al. Expression of CD44 3' untranslated region regulates endogenous microRNA functions in tumorigenesis and angiogenesis. Nucleic Acids Res. 39, 3026-3041 (2011).
    • (2011) Nucleic Acids Res , vol.39 , pp. 3026-3041
    • Jeyapalan, Z.1
  • 63
    • 84863083842 scopus 로고    scopus 로고
    • The non-coding 3' UTR of CD44 induces metastasis by regulating extracellular matrix functions
    • Rutnam Z. J, & Yang B. B. The non-coding 3' UTR of CD44 induces metastasis by regulating extracellular matrix functions. J. Cell Sci. 125, 2075-2085 (2012).
    • (2012) J. Cell Sci , vol.125 , pp. 2075-2085
    • Rutnam, Z.J.1    Yang, B.B.2
  • 64
    • 78149442860 scopus 로고    scopus 로고
    • Expression of versican 3' untranslated region modulates endogenous microRNA functions
    • Lee D. Y, et al. Expression of versican 3' untranslated region modulates endogenous microRNA functions. PLoS ONE. 5, e13599 (2010).
    • (2010) PLoS ONE , vol.5 , pp. e13599
    • Lee, D.Y.1
  • 65
    • 84906271393 scopus 로고    scopus 로고
    • FOXO1 3UTR functions as a ceRNA in repressing the metastases of breast cancer cells via regulating miRNA activity
    • Yang J, et al. FOXO1 3UTR functions as a ceRNA in repressing the metastases of breast cancer cells via regulating miRNA activity. FEBS Lett. 588, 3218-3224 (2014).
    • (2014) FEBS Lett , vol.588 , pp. 3218-3224
    • Yang, J.1
  • 66
    • 84927145743 scopus 로고    scopus 로고
    • OCT4B modulates OCT4A expression as ceRNA in tumor cells
    • Li D, et al. OCT4B modulates OCT4A expression as ceRNA in tumor cells. Oncol. Rep. 33, 2622-2630 (2015).
    • (2015) Oncol. Rep , vol.33 , pp. 2622-2630
    • Li, D.1
  • 67
    • 84939252155 scopus 로고    scopus 로고
    • AEG 1 3' untranslated region functions as a ceRNA in inducing epithelial-mesenchymal transition of human non-small cell lung cancer by regulating MIR 30a activity
    • Liu K, et al. AEG 1 3' untranslated region functions as a ceRNA in inducing epithelial-mesenchymal transition of human non-small cell lung cancer by regulating miR 30a activity. Eur. J. Cell Biol. 94, 22-31 (2015).
    • (2015) Eur. J. Cell Biol , vol.94 , pp. 22-31
    • Liu, K.1
  • 68
    • 80054700538 scopus 로고    scopus 로고
    • Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs
    • Tay Y, et al. Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs. Cell. 147, 344-357 (2011).
    • (2011) Cell , vol.147 , pp. 344-357
    • Tay, Y.1
  • 69
    • 80054681545 scopus 로고    scopus 로고
    • In vivo identification of tumor-suppressive PTEN ceRNAs in an oncogenic BRAF-induced mouse model of melanoma
    • Karreth F. A, et al. In vivo identification of tumor-suppressive PTEN ceRNAs in an oncogenic BRAF-induced mouse model of melanoma. Cell. 147, 382-395 (2011).
    • (2011) Cell , vol.147 , pp. 382-395
    • Karreth, F.A.1
  • 70
    • 80054689794 scopus 로고    scopus 로고
    • An extensive microRNA-mediated network of RNA-RNA interactions regulates established oncogenic pathways in glioblastoma
    • Sumazin P, et al. An extensive microRNA-mediated network of RNA-RNA interactions regulates established oncogenic pathways in glioblastoma. Cell. 147, 370-381 (2011).
    • (2011) Cell , vol.147 , pp. 370-381
    • Sumazin, P.1
  • 71
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis B. P, Burge C. B, & Bartel D. P. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell. 120, 15-20 (2005).
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 72
    • 14044251458 scopus 로고    scopus 로고
    • Human microRNA targets
    • John B, et al. Human microRNA targets. PLoS Biol. 2, e363 (2004).
    • (2004) PLoS Biol , vol.2 , pp. e363
    • John, B.1
  • 73
    • 84865138690 scopus 로고    scopus 로고
    • MiRcode: A map of putative microRNA target sites in the long non-coding transcriptome
    • Jeggari A, & Marks D. S, & Larsson E. miRcode: a map of putative microRNA target sites in the long non-coding transcriptome. Bioinformatics. 28, 2062-2063 (2012).
    • (2012) Bioinformatics , vol.28 , pp. 2062-2063
    • Jeggari, A.1    Marks, D.S.2    Larsson, E.3
  • 74
    • 84876523096 scopus 로고    scopus 로고
    • DIANA-LncBase: Experimentally verified and computationally predicted microRNA targets on long non-coding RNAs
    • Paraskevopoulou M. D, et al. DIANA-LncBase: experimentally verified and computationally predicted microRNA targets on long non-coding RNAs. Nucleic Acids Res. 41, D239-D245 (2013).
    • (2013) Nucleic Acids Res , vol.41 , pp. D239-D245
    • Paraskevopoulou, M.D.1
  • 75
    • 84961288501 scopus 로고    scopus 로고
    • The BRAF pseudogene functions as a competitive endogenous RNA and induces lymphoma in vivo
    • Karreth F. A, et al. The BRAF pseudogene functions as a competitive endogenous RNA and induces lymphoma in vivo. Cell. 161, 319-332 (2015).
    • (2015) Cell , vol.161 , pp. 319-332
    • Karreth, F.A.1
  • 76
    • 37349042903 scopus 로고    scopus 로고
    • Experimental validation of miRNA targets
    • Kuhn D. E, et al. Experimental validation of miRNA targets. Methods. 44, 47-54 (2008).
    • (2008) Methods , vol.44 , pp. 47-54
    • Kuhn, D.E.1
  • 77
    • 80052451056 scopus 로고    scopus 로고
    • Experimental strategies for microRNA target identification
    • Thomson D. W, Bracken C. P, & Goodall G. J. Experimental strategies for microRNA target identification. Nucleic Acids Res. 39, 6845-6853 (2011).
    • (2011) Nucleic Acids Res , vol.39 , pp. 6845-6853
    • Thomson, D.W.1    Bracken, C.P.2    Goodall, G.J.3
  • 79
    • 42449152837 scopus 로고    scopus 로고
    • Experimental validation of the importance of seed complement frequency to siRNA specificity
    • Anderson E. M, et al. Experimental validation of the importance of seed complement frequency to siRNA specificity. RNA. 14, 853-861 (2008).
    • (2008) RNA , vol.14 , pp. 853-861
    • Anderson, E.M.1
  • 80
    • 80455154984 scopus 로고    scopus 로고
    • Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy 6 and other microRNAs
    • Garcia D. M, et al. Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy 6 and other microRNAs. Nat. Struct. Mol. Biol. 18, 1139-1146 (2011).
    • (2011) Nat. Struct. Mol. Biol , vol.18 , pp. 1139-1146
    • Garcia, D.M.1
  • 81
    • 84908222388 scopus 로고    scopus 로고
    • Genome-wide identification of MIR 200 targets reveals a regulatory network controlling cell invasion
    • Bracken C. P, et al. Genome-wide identification of miR 200 targets reveals a regulatory network controlling cell invasion. EMBO J. 33, 2040-2056 (2014).
    • (2014) EMBO J. , vol.33 , pp. 2040-2056
    • Bracken, C.P.1
  • 82
    • 67749132423 scopus 로고    scopus 로고
    • Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps
    • Chi S. W, Zang J. B, Mele A, & Darnell R. B. Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. Nature. 460, 479-486 (2009).
    • (2009) Nature , vol.460 , pp. 479-486
    • Chi, S.W.1    Zang, J.B.2    Mele, A.3    Darnell, R.B.4
  • 83
    • 84865726286 scopus 로고    scopus 로고
    • The gencode pseudogene resource
    • Pei B, et al. The GENCODE pseudogene resource. Genome Biol. 13, R51 (2012).
    • (2012) Genome Biol , vol.13 , pp. R51
    • Pei, B.1
  • 84
    • 84923591343 scopus 로고    scopus 로고
    • Pseudogene-derived lncRNAs: Emerging regulators of gene expression
    • Milligan M. J, & Lipovich L. Pseudogene-derived lncRNAs: emerging regulators of gene expression. Front. Genet. 5, 476 (2014).
    • (2014) Front. Genet , vol.5 , pp. 476
    • Milligan, M.J.1    Lipovich, L.2
  • 85
    • 84901599553 scopus 로고    scopus 로고
    • A draft map of the human proteome
    • Kim M. S, et al A draft map of the human proteome. Nature. 509, 575-581 (2014).
    • (2014) Nature , vol.509 , pp. 575-581
    • Kim, M.S.1
  • 86
    • 84876580450 scopus 로고    scopus 로고
    • Molecular biology A circuitous route noncoding RNA
    • Wilusz J. E, & Sharp P. A. Molecular biology A circuitous route noncoding RNA. Science. 340, 440-441 (2013).
    • (2013) Science , vol.340 , pp. 440-441
    • Wilusz, J.E.1    Sharp, P.A.2
  • 87
    • 84924599473 scopus 로고    scopus 로고
    • The RNA binding protein quaking regulates formation of circRNAs
    • Conn S. J, et al. The RNA binding protein quaking regulates formation of circRNAs. Cell. 160, 1125-1134 (2015).
    • (2015) Cell , vol.160 , pp. 1125-1134
    • Conn, S.J.1
  • 88
    • 0027158771 scopus 로고
    • Circular transcripts of the testis-determining gene Sry in adult mouse testis
    • Capel B, et al. Circular transcripts of the testis-determining gene Sry in adult mouse testis. Cell. 73, 1019-1030 (1993).
    • (1993) Cell , vol.73 , pp. 1019-1030
    • Capel, B.1
  • 89
    • 84964240310 scopus 로고    scopus 로고
    • Circular RNAs in the mammalian brain are highly abundant, conserved, and dynamically expressed
    • Rybak-Wolf A, et al. Circular RNAs in the mammalian brain are highly abundant, conserved, and dynamically expressed. Mol. Cell (2015).
    • (2015) Mol. Cell
    • Rybak-Wolf, A.1
  • 90
    • 84911491114 scopus 로고    scopus 로고
    • Circular RNAs diversity of form and function
    • Lasda E, & Parker R. Circular RNAs: diversity of form and function. RNA. 20, 1829-1842 (2014).
    • (2014) RNA , vol.20 , pp. 1829-1842
    • Lasda, E.1    Parker, R.2
  • 91
    • 84956906428 scopus 로고    scopus 로고
    • Expanded identification and characterization of mammalian circular RNAs
    • Guo J. U, Agarwal V, Guo H, & Bartel D. P. Expanded identification and characterization of mammalian circular RNAs. Genome Biol. 15, 409 (2014).
    • (2014) Genome Biol , vol.15 , pp. 409
    • Guo, J.U.1    Agarwal, V.2    Guo, H.3    Bartel, D.P.4
  • 92
    • 84900322651 scopus 로고    scopus 로고
    • Detecting and characterizing circular RNAs
    • Jeck W. R, & Sharpless N. E. Detecting and characterizing circular RNAs. Nat. Biotechnol. 32, 453-461 (2014).
    • (2014) Nat. Biotechnol , vol.32 , pp. 453-461
    • Jeck, W.R.1    Sharpless, N.E.2
  • 93
    • 84872531655 scopus 로고    scopus 로고
    • Circular RNAs are abundant, conserved, and associated with ALU repeats
    • Jeck W. R, et al. Circular RNAs are abundant, conserved, and associated with ALU repeats. RNA. 19, 141-157 (2013).
    • (2013) RNA , vol.19 , pp. 141-157
    • Jeck, W.R.1
  • 94
    • 84925583141 scopus 로고    scopus 로고
    • Circular RNA ITCH has inhibitory effect on ESCC by suppressing the Wnt/β-catenin pathway
    • Li F, et al. Circular RNA ITCH has inhibitory effect on ESCC by suppressing the Wnt/β-catenin pathway. Oncotarget. 6, 6001-6013 (2015).
    • (2015) Oncotarget , vol.6 , pp. 6001-6013
    • Li, F.1
  • 95
    • 84901423529 scopus 로고    scopus 로고
    • A view of pre-mRNA splicing from RNase R resistant RNAs
    • Suzuki H, & Tsukahara T A view of pre-mRNA splicing from RNase R resistant RNAs. Int. J. Mol. Sci. 15, 9331-9342 (2014).
    • (2014) Int. J. Mol. Sci , vol.15 , pp. 9331-9342
    • Suzuki, H.1    Tsukahara, T.2
  • 96
    • 80455143733 scopus 로고    scopus 로고
    • MiRNA-dependent gene silencing involving Ago2 mediated cleavage of a circular antisense RNA
    • Hansen T. B, et al. miRNA-dependent gene silencing involving Ago2 mediated cleavage of a circular antisense RNA. EMBO J. 30, 4414-4422 (2011).
    • (2011) EMBO J. , vol.30 , pp. 4414-4422
    • Hansen, T.B.1
  • 97
    • 84944678160 scopus 로고    scopus 로고
    • RNA-mediated degradation of microRNAs: A widespread viral strategy?
    • McCaskill J, Praihirunkit P, Sharp P. M, & Buck A. H. RNA-mediated degradation of microRNAs: a widespread viral strategy?. RNA Biol. 12, 579-585 (2015).
    • (2015) RNA Biol , vol.12 , pp. 579-585
    • McCaskill, J.1    Praihirunkit, P.2    Sharp, P.M.3    Buck, A.H.4
  • 98
    • 84925240058 scopus 로고    scopus 로고
    • Viral noncoding RNAs: More surprises
    • Tycowski K. T, et al. Viral noncoding RNAs: more surprises. Genes Dev. 29, 567-584 (2015).
    • (2015) Genes Dev , vol.29 , pp. 567-584
    • Tycowski, K.T.1
  • 99
    • 0022749231 scopus 로고
    • Viral-encoded small RNAs in herpes virus saimiri induced tumors
    • Murthy S, Kamine J, & Desrosiers R. C. Viral-encoded small RNAs in herpes virus saimiri induced tumors. EMBO J. 5, 1625-1632 (1986).
    • (1986) EMBO J. , Issue.5 , pp. 1625-1632
    • Murthy, S.1    Kamine, J.2    Desrosiers, R.C.3
  • 101
    • 84898001469 scopus 로고    scopus 로고
    • Alternative capture of noncoding RNAs or protein-coding genes by herpesviruses to alter host T cell function
    • Guo Y. E, Riley K. J, Iwasaki A, & Steitz J. A. Alternative capture of noncoding RNAs or protein-coding genes by herpesviruses to alter host T cell function. Mol. Cell. 54, 67-79 (2014).
    • (2014) Mol. Cell , vol.54 , pp. 67-79
    • Guo, Y.E.1    Riley, K.J.2    Iwasaki, A.3    Steitz, J.A.4
  • 102
    • 46749124698 scopus 로고    scopus 로고
    • Position-dependent function for a tandem microRNA MIR 122 binding site located in the hepatitis C virus RNA genome
    • Jopling C. L, Schutz S, & Sarnow P. Position-dependent function for a tandem microRNA miR 122 binding site located in the hepatitis C virus RNA genome. Cell Host Microbe. 4, 77-85 (2008).
    • (2008) Cell Host Microbe , vol.4 , pp. 77-85
    • Jopling, C.L.1    Schutz, S.2    Sarnow, P.3
  • 103
    • 79952768199 scopus 로고    scopus 로고
    • Masking the 5' terminal nucleotides of the hepatitis C virus genome by an unconventional microRNA-Target RNA complex
    • Machlin E. S, Sarnow P, & Sagan S. M. Masking the 5' terminal nucleotides of the hepatitis C virus genome by an unconventional microRNA-Target RNA complex. Proc. Natl Acad. Sci. USA. 108, 3193-3198 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 3193-3198
    • Machlin, E.S.1    Sarnow, P.2    Sagan, S.M.3
  • 104
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs target recognition and regulatory functions
    • Bartel D. P. MicroRNAs: target recognition and regulatory functions. Cell. 136, 215-233 (2009).
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 105
    • 84933034424 scopus 로고    scopus 로고
    • PTEN ceRNA networks in human cancer
    • Poliseno L, & Pandolfi P. P. PTEN ceRNA networks in human cancer. Methods 77-78, 41-50 (2015).
    • (2015) Methods 77-78 , pp. 41-50
    • Poliseno, L.1    Pandolfi, P.P.2
  • 106
    • 84886910303 scopus 로고    scopus 로고
    • Emerging roles of competing endogenous RNAs in cancer: Insights from the regulation of PTEN
    • de Giorgio A, Krell J, Harding V, Stebbing J, & Castellano L. Emerging roles of competing endogenous RNAs in cancer: insights from the regulation of PTEN. Mol. Cell. Biol. 33, 3976-3982 (2013).
    • (2013) Mol. Cell. Biol , vol.33 , pp. 3976-3982
    • De Giorgio, A.1    Krell, J.2    Harding, V.3    Stebbing, J.4    Castellano, L.5
  • 107
    • 13944282215 scopus 로고    scopus 로고
    • Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
    • Lim L. P, et al. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature. 433, 769-773 (2005).
    • (2005) Nature , vol.433 , pp. 769-773
    • Lim, L.P.1
  • 108
    • 49949116902 scopus 로고    scopus 로고
    • The impact of microRNAs on protein output
    • Baek D, et al. The impact of microRNAs on protein output. Nature. 455, 64-71 (2008).
    • (2008) Nature , vol.455 , pp. 64-71
    • Baek, D.1
  • 109
    • 72949115517 scopus 로고    scopus 로고
    • Concordant regulation of translation and mRNA abundance for hundreds of targets of a human microRNA
    • Hendrickson D. G, et al. Concordant regulation of translation and mRNA abundance for hundreds of targets of a human microRNA. PLoS Biol. 7, e1000238 (2009).
    • (2009) PLoS Biol , vol.7 , pp. e1000238
    • Hendrickson, D.G.1
  • 110
    • 84941087952 scopus 로고    scopus 로고
    • DIANA-TarBase v7.0: Indexing more than half a million experimentally supported miRNA: mRNA interactions
    • Vlachos I. S, et al. DIANA-TarBase v7.0: indexing more than half a million experimentally supported miRNA: mRNA interactions. Nucleic Acids Res. 43, D153-D159 (2015).
    • (2015) Nucleic Acids Res , vol.43 , pp. D153-D159
    • Vlachos, I.S.1
  • 111
    • 84892573723 scopus 로고    scopus 로고
    • The multilayered complexity of ceRNA crosstalk and competition
    • Tay Y, Rinn J, & Pandolfi P. P. The multilayered complexity of ceRNA crosstalk and competition. Nature. 505, 344-352 (2014).
    • (2014) Nature , vol.505 , pp. 344-352
    • Tay, Y.1    Rinn, J.2    Pandolfi, P.P.3
  • 112
    • 77955475953 scopus 로고    scopus 로고
    • Expanding the microRNA targeting code: Functional sites with centered pairing
    • Shin C, et al. Expanding the microRNA targeting code: functional sites with centered pairing. Mol. Cell. 38, 789-802 (2010).
    • (2010) Mol. Cell , vol.38 , pp. 789-802
    • Shin, C.1
  • 113
    • 84857955708 scopus 로고    scopus 로고
    • An alternative mode of microRNA target recognition
    • Chi S. W, Hannon G. J, & Darnell R. B. An alternative mode of microRNA target recognition. Nat. Struct. Mol. Biol. 19, 321-327 (2012).
    • (2012) Nat Struct. Mol. Biol , vol.19 , pp. 321-327
    • Chi, S.W.1    Hannon, G.J.2    Darnell, R.B.3
  • 114
    • 74049088856 scopus 로고    scopus 로고
    • Lost in translation: An assessment and perspective for computational microRNA target identification
    • Alexiou P, Maragkakis M, Papadopoulos G. L, Reczko M, & Hatzigeorgiou A. G. Lost in translation: an assessment and perspective for computational microRNA target identification. Bioinformatics. 25, 3049-3055 (2009).
    • (2009) Bioinformatics , vol.25 , pp. 3049-3055
    • Alexiou, P.1    Maragkakis, M.2    Papadopoulos, G.L.3    Reczko, M.4    Hatzigeorgiou, A.G.5
  • 115
    • 66249106716 scopus 로고    scopus 로고
    • Predicting microRNA targets and functions: Traps for the unwary
    • Ritchie W, Flamant S, & Rasko J. E. Predicting microRNA targets and functions: traps for the unwary. Nat. Methods. 6, 397-398 (2009).
    • (2009) Nat. Methods , vol.6 , pp. 397-398
    • Ritchie, W.1    Flamant, S.2    Rasko, J.E.3
  • 116
    • 84882643385 scopus 로고    scopus 로고
    • Linc2GO: A human LincRNA function annotation resource based on ceRNA hypothesis
    • Liu K, Yan Z, Li Y, & Sun Z. Linc2GO: a human LincRNA function annotation resource based on ceRNA hypothesis. Bioinformatics. 29, 2221-2222 (2013).
    • (2013) Bioinformatics , vol.29 , pp. 2221-2222
    • Liu, K.1    Yan, Z.2    Li, Y.3    Sun, Z.4
  • 117
    • 84906279462 scopus 로고    scopus 로고
    • HumanViCe: Host ceRNA network in virus infected cells in human
    • Ghosal S, Das S, Sen R, & Chakrabarti J. HumanViCe: host ceRNA network in virus infected cells in human. Front. Genet. 5, 249 (2014).
    • (2014) Front. Genet , vol.5 , pp. 249
    • Ghosal, S.1    Das, S.2    Sen, R.3    Chakrabarti, J.4
  • 118
    • 34249849395 scopus 로고    scopus 로고
    • Discovery of microRNA-mRNA modules via population-based probabilistic learning
    • Joung J. G, Hwang K. B, Nam J. W, Kim S. J, & Zhang B. T. Discovery of microRNA-mRNA modules via population-based probabilistic learning. Bioinformatics. 23, 1141-1147 (2007).
    • (2007) Bioinformatics , vol.23 , pp. 1141-1147
    • Joung, J.G.1    Hwang, K.B.2    Nam, J.W.3    Kim, S.J.4    Zhang, B.T.5
  • 119
    • 57649228450 scopus 로고    scopus 로고
    • Finding microRNA regulatory modules in human genome using rule induction
    • Tran D. H, Satou K, & Ho T. B. Finding microRNA regulatory modules in human genome using rule induction. BMC Bioinformatics. 9, S5 (2008).
    • (2008) BMC Bioinformatics , vol.9 , pp. S5
    • Tran, D.H.1    Satou, K.2    Ho, T.B.3
  • 120
    • 84861909720 scopus 로고    scopus 로고
    • Identification of microRNA-regulated gene networks by expression analysis of target genes
    • Gennarino V. A, et al. Identification of microRNA-regulated gene networks by expression analysis of target genes. Genome Res. 22, 1163-1172 (2012).
    • (2012) Genome Res , vol.22 , pp. 1163-1172
    • Gennarino, V.A.1
  • 121
    • 84906241067 scopus 로고    scopus 로고
    • Long noncoding RNA associated-competing endogenous RNAs in gastric cancer
    • Xia T, et al. Long noncoding RNA associated-competing endogenous RNAs in gastric cancer. Sci. Rep. 4, 6088 (2014).
    • (2014) Sci. Rep , vol.4 , pp. 6088
    • Xia, T.1
  • 122
    • 84941101305 scopus 로고    scopus 로고
    • Assessing the gene regulatory properties of Argonaute-bound small RNAs of diverse genomic origin
    • Thomson D. W, et al. Assessing the gene regulatory properties of Argonaute-bound small RNAs of diverse genomic origin. Nucleic Acids Res. 43, 470-481(2014).
    • (2014) Nucleic Acids Res , vol.43 , pp. 470-481
    • Thomson, D.W.1
  • 123
    • 77950920903 scopus 로고    scopus 로고
    • Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP
    • Hafner M, et al. Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP. Cell. 141, 129-141 (2010).
    • (2010) Cell , vol.141 , pp. 129-141
    • Hafner, M.1
  • 124
    • 84870038812 scopus 로고    scopus 로고
    • Argonaute divides its RNA guide into domains with distinct functions and RNA-binding properties
    • Wee L. M, Flores-Jasso C. F, Salomon W. E, & Zamore P. D. Argonaute divides its RNA guide into domains with distinct functions and RNA-binding properties. Cell. 151, 1055-1067 (2012).
    • (2012) Cell , vol.151 , pp. 1055-1067
    • Wee, L.M.1    Flores-Jasso, C.F.2    Salomon, W.E.3    Zamore, P.D.4
  • 125
    • 84857066786 scopus 로고    scopus 로고
    • Modular regulatory principles of large non-coding RNAs
    • Guttman M, & Rinn J. L. Modular regulatory principles of large non-coding RNAs. Nature. 482, 339-346 (2012).
    • (2012) Nature , vol.482 , pp. 339-346
    • Guttman, M.1    Rinn, J.L.2
  • 126
    • 84903792862 scopus 로고    scopus 로고
    • Anti-miRs competitively inhibit microRNAs in Argonaute complexes
    • Hogan D. J, et al. Anti-miRs competitively inhibit microRNAs in Argonaute complexes. PLoS ONE. 9, e100951 (2014).
    • (2014) PLoS ONE , vol.9 , pp. e100951
    • Hogan, D.J.1
  • 127
    • 84953351897 scopus 로고    scopus 로고
    • The specificity of long noncoding RNA expression
    • Gloss B. S, & Dinger M. E. The specificity of long noncoding RNA expression. Biochim. Biophys. Acta 1859, 16-22 (2015).
    • (2015) Biochim. Biophys. Acta , vol.1859 , pp. 16-22
    • Gloss, B.S.1    Dinger, M.E.2
  • 128
    • 84929657536 scopus 로고    scopus 로고
    • Extensive microRNA-mediated crosstalk between lncRNAs and mRNAs in mouse embryonic stem cells
    • Tan J. Y, et al. Extensive microRNA-mediated crosstalk between lncRNAs and mRNAs in mouse embryonic stem cells. Genome Res. 25, 655-666 (2015).
    • (2015) Genome Res , vol.25 , pp. 655-666
    • Tan, J.Y.1
  • 129
    • 84860581983 scopus 로고    scopus 로고
    • Genome-wide analysis of long noncoding RNA stability
    • Clark M. B, et al. Genome-wide analysis of long noncoding RNA stability. Genome Res. 22, 885-898 (2012).
    • (2012) Genome Res , vol.22 , pp. 885-898
    • Clark, M.B.1
  • 130
    • 84896397929 scopus 로고    scopus 로고
    • Global analyses of the effect of different cellular contexts on microRNA targeting
    • Nam J. W, et al. Global analyses of the effect of different cellular contexts on microRNA targeting. Mol. Cell. 53, 1031-1043 (2014).
    • (2014) Mol. Cell , vol.53 , pp. 1031-1043
    • Nam, J.W.1
  • 131
    • 80052191259 scopus 로고    scopus 로고
    • Global analysis of the mammalian RNA degradome reveals widespread miRNA-dependent and miRNA-independent endonucleolytic cleavage
    • Bracken C. P, et al. Global analysis of the mammalian RNA degradome reveals widespread miRNA-dependent and miRNA-independent endonucleolytic cleavage. Nucleic Acids Res. 39, 5658-5668 (2011).
    • (2011) Nucleic Acids Res , vol.39 , pp. 5658-5668
    • Bracken, C.P.1
  • 132
    • 84936744064 scopus 로고    scopus 로고
    • Analysis of CLIP and iCLIP methods for nucleotide-resolution studies of protein-RNA interactions
    • Sugimoto Y, et al. Analysis of CLIP and iCLIP methods for nucleotide-resolution studies of protein-RNA interactions. Genome Biol. 13, R67 (2012).
    • (2012) Genome Biol , vol.13 , pp. R67
    • Sugimoto, Y.1
  • 133
    • 84873560641 scopus 로고    scopus 로고
    • Quantifying Argonaute proteins in and out of GW/P bodies: Implications in microRNA activities
    • Leung A. K, & Sharp P. A. Quantifying Argonaute proteins in and out of GW/P bodies: implications in microRNA activities. Adv. Exp. Med. Biol. 768, 165-182 (2013).
    • (2013) Adv. Exp. Med. Biol , vol.768 , pp. 165-182
    • Leung, A.K.1    Sharp, P.A.2
  • 134
    • 84902462961 scopus 로고    scopus 로고
    • A dosage-dependent pleiotropic role of Dicer in prostate cancer growth and metastasis
    • Zhang B, et al A dosage-dependent pleiotropic role of Dicer in prostate cancer growth and metastasis. Oncogene. 33, 3099-3108 (2014).
    • (2014) Oncogene , vol.33 , pp. 3099-3108
    • Zhang, B.1
  • 135
    • 34249025114 scopus 로고    scopus 로고
    • Prediction of microRNA targets
    • Maziere P, & Enright A. J. Prediction of microRNA targets. Drug Discov. Today. 12, 452-458 (2007).
    • (2007) Drug Discov. Today , vol.12 , pp. 452-458
    • Maziere, P.1    Enright, A.J.2
  • 136
    • 33749077734 scopus 로고    scopus 로고
    • Prediction of microRNA targets
    • Rehmsmeier M. Prediction of microRNA targets. Methods Mol. Biol. 342, 87-99 (2006).
    • (2006) Methods Mol. Biol , vol.342 , pp. 87-99
    • Rehmsmeier, M.1
  • 137
    • 84949745048 scopus 로고    scopus 로고
    • Computational prediction of microRNA targets
    • Lagana A. Computational prediction of microRNA targets. Adv. Exp. Med. Biol. 887, 231-252 (2015).
    • (2015) Adv. Exp. Med. Biol , vol.887 , pp. 231-252
    • Lagana, A.1
  • 138
    • 79952108909 scopus 로고    scopus 로고
    • Computational prediction of microRNA targets
    • Wang X. Computational prediction of microRNA targets. Methods Mol. Biol. 667, 283-295 (2010).
    • (2010) Methods Mol. Biol , vol.667 , pp. 283-295
    • Wang, X.1
  • 140
    • 34748821761 scopus 로고    scopus 로고
    • The role of site accessibility in microRNA target recognition
    • Kertesz M, Iovino N, Unnerstall U, Gaul U, & Segal E. The role of site accessibility in microRNA target recognition. Nat. Genet. 39, 1278-1284 (2007).
    • (2007) Nat. Genet , vol.39 , pp. 1278-1284
    • Kertesz, M.1    Iovino, N.2    Unnerstall, U.3    Gaul, U.4    Segal, E.5
  • 141
    • 77955963884 scopus 로고    scopus 로고
    • Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites
    • Betel D, Koppal A, Agius P, Sander C, & Leslie C. Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites. Genome Biol. 11, R90 (2010).
    • (2010) Genome Biol , vol.11 , pp. R90
    • Betel, D.1    Koppal, A.2    Agius, P.3    Sander, C.4    Leslie, C.5
  • 142
    • 84868137211 scopus 로고    scopus 로고
    • A new microRNA target prediction tool identifies a novel interaction of a putative miRNA with CCND2
    • Oulas A, et al. A new microRNA target prediction tool identifies a novel interaction of a putative miRNA with CCND2. RNA Biol. 9, 1196-1207 (2012).
    • (2012) RNA Biol , vol.9 , pp. 1196-1207
    • Oulas, A.1
  • 143
    • 2442672918 scopus 로고    scopus 로고
    • A combined computational-experimental approach predicts human microRNA targets
    • Kiriakidou M, et al A combined computational-experimental approach predicts human microRNA targets. Genes Dev. 18, 1165-1178 (2004).
    • (2004) Genes Dev , vol.18 , pp. 1165-1178
    • Kiriakidou, M.1
  • 144
    • 84903200695 scopus 로고    scopus 로고
    • 3'UTR shortening identifies high-risk cancers with targeted dysregulation of the ceRNA network
    • Li L, et al. 3'UTR shortening identifies high-risk cancers with targeted dysregulation of the ceRNA network. Sci. Rep. 4, 5406 (2014).
    • (2014) Sci. Rep , vol.4 , pp. 5406
    • Li, L.1
  • 145
    • 84937605789 scopus 로고    scopus 로고
    • RNA-binding protein HuR sequesters microRNA 21 to prevent translation repression of proinflammatory tumor suppressor gene programmed cell death 4
    • Poria D. K, Guha A, Nandi I, & Ray P. S. RNA-binding protein HuR sequesters microRNA 21 to prevent translation repression of proinflammatory tumor suppressor gene programmed cell death 4. Oncogene http://dx.doi.org/10.1038/onc.2015.235 (2015).
    • (2015) Oncogene , vol.2015 , pp. 235
    • Poria, D.K.1    Guha, A.2    Nandi, I.3    Ray, P.S.4
  • 146
    • 84951284507 scopus 로고    scopus 로고
    • Get in LINE: Competition for newly minted retrotransposon proteins at the ribosome
    • Floor S. N, & Doudna J. A. Get in LINE: Competition for newly minted retrotransposon proteins at the ribosome. Mol. Cell. 60, 712-714 (2015).
    • (2015) Mol. Cell , vol.60 , pp. 712-714
    • Floor, S.N.1    Doudna, J.A.2


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