메뉴 건너뛰기




Volumn 9, Issue 8, 2012, Pages 840-846

High-throughput assessment of microRNA activity and function using microRNA sensor and decoy libraries

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 122; MICRORNA 142; MICRORNA 16; MICRORNA 21; MICRORNA 22; MICRORNA 223; MICRORNA 331; MICRORNA 9; UNCLASSIFIED DRUG;

EID: 84864448111     PISSN: 15487091     EISSN: 15487105     Source Type: Journal    
DOI: 10.1038/nmeth.2078     Document Type: Article
Times cited : (318)

References (48)
  • 2
    • 3042767202 scopus 로고    scopus 로고
    • MicroRNAs: Small RNAs with a big role in gene regulation
    • DOI 10.1038/nrg1379
    • He, L. & Hannon, G.J. MicroRNAs: small RNAs with a big role in gene regulation. Nat. Rev. Genet. 5, 522-531 (2004). (Pubitemid 38868508)
    • (2004) Nature Reviews Genetics , vol.5 , Issue.7 , pp. 522-531
    • He, L.1    Hannon, G.J.2
  • 3
    • 58249088751 scopus 로고    scopus 로고
    • Micrornas: Target recognition and regulatory functions
    • Bartel, D.P. MicroRNAs: target recognition and regulatory functions. Cell 136, 215-233 (2009).
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 4
    • 67651087321 scopus 로고    scopus 로고
    • Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications
    • Brown, B.D. & Naldini, L. Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications. Nat. Rev. Genet. 10, 578-585 (2009).
    • (2009) Nat. Rev. Genet , vol.10 , pp. 578-585
    • Brown, B.D.1    Naldini, L.2
  • 6
    • 33646721162 scopus 로고    scopus 로고
    • A novel assay for viral microrna function identifies A single nucleotide polymorphism that affects drosha processing
    • Gottwein, E., Cai, X. & Cullen, B.R. A novel assay for viral microRNA function identifies a single nucleotide polymorphism that affects Drosha processing. J. Virol. 80, 5321-5326 (2006).
    • (2006) J. Virol , vol.80 , pp. 5321-5326
    • Gottwein, E.1    Cai, X.2    Cullen, B.R.3
  • 7
    • 33646564701 scopus 로고    scopus 로고
    • Endogenous microrna regulation suppresses transgene expression in hematopoietic lineages and enables stable gene transfer
    • Brown, B.D., Venneri, M.A., Zingale, A., Sergi Sergi, L. & Naldini, L. Endogenous microRNA regulation suppresses transgene expression in hematopoietic lineages and enables stable gene transfer. Nat. Med. 12, 585-591 (2006).
    • (2006) Nat. Med , vol.12 , pp. 585-591
    • Brown, B.D.1    Venneri, M.A.2    Zingale, A.3    Sergi Sergi, L.4    Naldini, L.5
  • 8
    • 55549100223 scopus 로고    scopus 로고
    • Engineering microrna responsiveness to decrease virus pathogenicity
    • Kelly, E.J., Hadac, E.M., Greiner, S. & Russell, S.J. Engineering microRNA responsiveness to decrease virus pathogenicity. Nat. Med. 14, 1278-1283 (2008).
    • (2008) Nat. Med , vol.14 , pp. 1278-1283
    • Kelly, E.J.1    Hadac, E.M.2    Greiner, S.3    Russell, S.J.4
  • 9
    • 51049109002 scopus 로고    scopus 로고
    • Harnessing endogenous mirnas to control virus tissue tropism as a strategy for developing attenuated virus vaccines
    • Barnes, D., Kunitomi, M., Vignuzzi, M., Saksela, K. & Andino, R. Harnessing endogenous miRNAs to control virus tissue tropism as a strategy for developing attenuated virus vaccines. Cell Host Microbe 4, 239-248 (2008).
    • (2008) Cell Host Microbe , vol.4 , pp. 239-248
    • Barnes, D.1    Kunitomi, M.2    Vignuzzi, M.3    Saksela, K.4    Andino, R.5
  • 10
    • 78449270317 scopus 로고    scopus 로고
    • Identification of hematopoietic stem cell-specific miRNAs enables gene therapy of globoid cell leukodystrophy
    • Gentner, B. et al. Identification of hematopoietic stem cell-specific miRNAs enables gene therapy of globoid cell leukodystrophy. Sci. Transl. Med. 2, 58ra84 (2010).
    • (2010) Sci. Transl. Med. , vol.2
    • Gentner, B.1
  • 12
    • 34548316982 scopus 로고    scopus 로고
    • MicroRNA sponges: Competitive inhibitors of small RNAs in mammalian cells
    • DOI 10.1038/nmeth1079, PII NMETH1079
    • Ebert, M.S., Neilson, J.R. & Sharp, P.A. MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nat. Methods 4, 721-726 (2007). (Pubitemid 47338166)
    • (2007) Nature Methods , vol.4 , Issue.9 , pp. 721-726
    • Ebert, M.S.1    Neilson, J.R.2    Sharp, P.A.3
  • 13
    • 58149252151 scopus 로고    scopus 로고
    • Stable knockdown of microrna in vivo by lentiviral vectors
    • Gentner, B. et al. Stable knockdown of microRNA in vivo by lentiviral vectors. Nat. Methods 6, 63-66 (2009).
    • (2009) Nat. Methods , vol.6 , pp. 63-66
    • Gentner, B.1
  • 14
    • 64549109671 scopus 로고    scopus 로고
    • Vectors expressing efficient RNA decoys achieve the long-term suppression of specific microrna activity in mammalian cells
    • Haraguchi, T., Ozaki, Y. & Iba, H. Vectors expressing efficient RNA decoys achieve the long-term suppression of specific microRNA activity in mammalian cells. Nucleic Acids Res. 37, e43 (2009).
    • (2009) Nucleic Acids Res , vol.37
    • Haraguchi, T.1    Ozaki, Y.2    Iba, H.3
  • 16
    • 79956322553 scopus 로고    scopus 로고
    • Global quantification of mammalian gene expression control
    • Schwanhäusser, B. et al. Global quantification of mammalian gene expression control. Nature 473, 337-342 (2011).
    • (2011) Nature , vol.473 , pp. 337-342
    • Schwanhäusser, B.1
  • 17
    • 79952364512 scopus 로고    scopus 로고
    • Kinetic analysis reveals the fate of a microrna following target regulation in mammalian cells
    • Baccarini, A. et al. Kinetic analysis reveals the fate of a microRNA following target regulation in mammalian cells. Curr. Biol. 21, 369-376 (2011).
    • (2011) Curr. Biol , vol.21 , pp. 369-376
    • Baccarini, A.1
  • 18
    • 77950920903 scopus 로고    scopus 로고
    • Transcriptome-wide identification of rna-binding protein and microrna target sites by PAR-CLIP
    • Hafner, M. et al. Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP. Cell 141, 129-141 (2010).
    • (2010) Cell , vol.141 , pp. 129-141
    • Hafner, M.1
  • 19
    • 82255185567 scopus 로고    scopus 로고
    • Identification and remediation of biases in the activity of RNA ligases in small-rna deep sequencing
    • Jayaprakash, A.D., Jabado, O., Brown, B.D. & Sachidanandam, R. Identification And remediation of biases in the activity of RNA ligases in small-rna deep sequencing. Nucleic Acids Res. 39, e141 (2011).
    • (2011) Nucleic Acids Res. , vol.39
    • Jayaprakash, A.D.1    Jabado, O.2    Brown, B.D.3    Sachidanandam, R.4
  • 21
    • 69949154245 scopus 로고    scopus 로고
    • Zcchc11-dependent uridylation of microRNA directs cytokine expression
    • Jones, M.R. et al. Zcchc11-dependent uridylation of microRNA directs cytokine expression. Nat. Cell Biol. 11, 1157-1163 (2009).
    • (2009) Nat. Cell Biol , vol.11 , pp. 1157-1163
    • Jones, M.R.1
  • 22
    • 80054715378 scopus 로고    scopus 로고
    • A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA
    • Cesana, M. et al. A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA. Cell 147, 358-369 (2011).
    • (2011) Cell , vol.147 , pp. 358-369
    • Cesana, M.1
  • 24
    • 80455154984 scopus 로고    scopus 로고
    • Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other micrornas
    • Garcia, D.M. et al. Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs. Nat. Struct. Mol. Biol. 18, 1139-1146 (2011).
    • (2011) Nat. Struct. Mol. Biol , vol.18 , pp. 1139-1146
    • Garcia, D.M.1
  • 25
    • 49949117302 scopus 로고    scopus 로고
    • Widespread changes in protein synthesis induced by micrornas
    • Selbach, M. et al. Widespread changes in protein synthesis induced by microRNAs. Nature 455, 58-63 (2008).
    • (2008) Nature , vol.455 , pp. 58-63
    • Selbach, M.1
  • 26
    • 73349122330 scopus 로고    scopus 로고
    • Transgenic microRNA inhibition with spatiotemporal specificity in intact organisms
    • Loya, C.M., Lu, C.S., Van Vactor, D. & Fulga, T.A. Transgenic microRNA inhibition with spatiotemporal specificity in intact organisms. Nat. Methods 6, 897-903 (2009).
    • (2009) Nat. Methods , vol.6 , pp. 897-903
    • Loya, C.M.1    Lu, C.S.2    Van Vactor, D.3    Fulga, T.A.4
  • 27
    • 84862805889 scopus 로고    scopus 로고
    • Long-term, efficient inhibition of microrna function in mice using raav vectors
    • Xie, J. et al. Long-term, efficient inhibition of microRNA function in mice using rAAV vectors. Nat. Methods 9, 403-409 (2012).
    • (2012) Nat. Methods , vol.9 , pp. 403-409
    • Xie, J.1
  • 28
    • 24644483623 scopus 로고    scopus 로고
    • Molecular biology: Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA
    • DOI 10.1126/science.1113329
    • Jopling, C.L., Yi, M., Lancaster, A.M., Lemon, S.M. & Sarnow, P. Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA. Science 309, 1577-1581 (2005). (Pubitemid 41266486)
    • (2005) Science , vol.309 , Issue.5740 , pp. 1577-1581
    • Jopling, C.L.1    Yi, M.2    Lancaster, A.M.3    Lemon, S.M.4    Sarnow, P.5
  • 29
    • 84858446579 scopus 로고    scopus 로고
    • MicroRNAs and their targets: Recognition, regulation and an emerging reciprocal relationship
    • Pasquinelli, A.E. MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship. Nat. Rev. Genet. 13, 271-282 (2012).
    • (2012) Nat. Rev. Genet , vol.13 , pp. 271-282
    • Pasquinelli, A.E.1
  • 30
    • 67349123973 scopus 로고    scopus 로고
    • Redefining microRNA targets
    • Seitz, H. Redefining microRNA targets. Curr. Biol. 19, 870-873 (2009).
    • (2009) Curr. Biol , vol.19 , pp. 870-873
    • Seitz, H.1
  • 31
    • 0037144546 scopus 로고    scopus 로고
    • A microrna in a multiple-turnover RNAi enzyme complex
    • Hutvágner, G. & Zamore, P.D. A microRNA in a multiple-turnover RNAi enzyme complex. Science 297, 2056-2060 (2002).
    • (2002) Science , vol.297 , pp. 2056-2060
    • Hutvágner, G.1    Zamore, P.D.2
  • 32
    • 3042602447 scopus 로고    scopus 로고
    • Kinetic analysis of the RNAi enzyme complex
    • DOI 10.1038/nsmb780
    • Haley, B. & Zamore, P.D. Kinetic analysis of the RNAi enzyme complex. Nat. Struct. Mol. Biol. 11, 599-606 (2004). (Pubitemid 38823525)
    • (2004) Nature Structural and Molecular Biology , vol.11 , Issue.7 , pp. 599-606
    • Haley, B.1    Zamore, P.D.2
  • 33
    • 33846699083 scopus 로고    scopus 로고
    • A hexanucleotide element directs microRNA nuclear import
    • DOI 10.1126/science.1136235
    • Hwang, H.W., Wentzel, E.A. & Mendell, J.T. A hexanucleotide element directs microRNA nuclear import. Science 315, 97-100 (2007). (Pubitemid 46196987)
    • (2007) Science , vol.315 , Issue.5808 , pp. 97-100
    • Hwang, H.-W.1    Wentzel, E.A.2    Mendell, J.T.3
  • 34
    • 77955902024 scopus 로고    scopus 로고
    • The widespread regulation of microRNA biogenesis, function and decay
    • Krol, J., Loedige, I. & Filipowicz, W. The widespread regulation of microRNA biogenesis, function and decay. Nat. Rev. Genet. 11, 597-610 (2010).
    • (2010) Nat. Rev. Genet , vol.11 , pp. 597-610
    • Krol, J.1    Loedige, I.2    Filipowicz, W.3
  • 35
    • 79960987021 scopus 로고    scopus 로고
    • A public genome-scale lentiviral expression library of human orfs
    • Yang, X. et al. A public genome-scale lentiviral expression library of human ORFs. Nat. Methods 8, 659-661 (2011).
    • (2011) Nat. Methods , vol.8 , pp. 659-661
    • Yang, X.1
  • 36
    • 79955594279 scopus 로고    scopus 로고
    • A genome-scale shRNA resource for transgenic RNAi in drosophila
    • Ni, J.Q. et al. A genome-scale shRNA resource for transgenic RNAi in Drosophila. Nat. Methods 8, 405-407 (2011).
    • (2011) Nat. Methods , vol.8 , pp. 405-407
    • Ni, J.Q.1
  • 37
    • 20844438492 scopus 로고    scopus 로고
    • Production of complex nucleic acid libraries using highly parallel in situ oligonucleotide synthesis
    • Cleary, M.A. et al. Production of complex nucleic acid libraries using highly parallel in situ oligonucleotide synthesis. Nat. Methods 1, 241-248 (2004).
    • (2004) Nat. Methods , vol.1 , pp. 241-248
    • Cleary, M.A.1
  • 38
    • 67349251607 scopus 로고    scopus 로고
    • Rapid creation and quantitative monitoring of high coverage shRNA libraries
    • Bassik, M.C. et al. Rapid creation and quantitative monitoring of high coverage shRNA libraries. Nat. Methods 6, 443-445 (2009).
    • (2009) Nat. Methods , vol.6 , pp. 443-445
    • Bassik, M.C.1
  • 39
    • 15244351083 scopus 로고    scopus 로고
    • Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters
    • DOI 10.1038/nbt1049
    • Amendola, M., Venneri, M.A., Biffi, A., Vigna, E. & Naldini, L. Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters. Nat. Biotechnol. 23, 108-116 (2005). (Pubitemid 41724633)
    • (2005) Nature Biotechnology , vol.23 , Issue.1 , pp. 108-116
    • Amendola, M.1    Venneri, M.A.2    Biffi, A.3    Vigna, E.4    Naldini, L.5
  • 40
    • 79952109878 scopus 로고    scopus 로고
    • Monitoring microRNA activity and validating microRNA targets by reporter-based approaches
    • Baccarini, A. & Brown, B.D. Monitoring microRNA activity and validating microRNA targets by reporter-based approaches. Methods Mol. Biol. 667, 215-233 (2010).
    • (2010) Methods Mol. Biol , vol.667 , pp. 215-233
    • Baccarini, A.1    Brown, B.D.2
  • 41
    • 65549105694 scopus 로고    scopus 로고
    • Specialized piRNA pathways act in germline and somatic tissues of the drosophila ovary
    • Malone, C.D. et al. Specialized piRNA pathways act in germline and somatic tissues of the Drosophila ovary. Cell 137, 522-535 (2009).
    • (2009) Cell , vol.137 , pp. 522-535
    • Malone, C.D.1
  • 42
    • 82255185567 scopus 로고    scopus 로고
    • Identification and remediation of biases in the activity of RNA ligases in small-RNA deep sequencing
    • Jayaprakash, A.D., Jabado, O., Brown, B.D. & Sachidanandam, R. Identification and remediation of biases in the activity of RNA ligases in small-RNA deep sequencing. Nucleic Acids Res. 39, e141 (2011).
    • (2011) Nucleic Acids Res , vol.39
    • Jayaprakash, A.D.1    Jabado, O.2    Brown, B.D.3    Sachidanandam, R.4
  • 43
    • 33947273235 scopus 로고    scopus 로고
    • Discrete Small RNA-Generating Loci as Master Regulators of Transposon Activity in Drosophila
    • DOI 10.1016/j.cell.2007.01.043, PII S0092867407002577
    • Brennecke, J. et al. Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila. Cell 128, 1089-1103 (2007). (Pubitemid 46427877)
    • (2007) Cell , vol.128 , Issue.6 , pp. 1089-1103
    • Brennecke, J.1    Aravin, A.A.2    Stark, A.3    Dus, M.4    Kellis, M.5    Sachidanandam, R.6    Hannon, G.J.7
  • 44
    • 33745336617 scopus 로고    scopus 로고
    • A germline-specific class of small RNAs binds mammalian Piwi proteins
    • DOI 10.1038/nature04917, PII NATURE04917
    • Girard, A., Sachidanandam, R., Hannon, G.J. & Carmell, M.A. A germline-specific class of small RNAs binds mammalian Piwi proteins. Nature 442, 199-202 (2006). (Pubitemid 44086566)
    • (2006) Nature , vol.442 , Issue.7099 , pp. 199-202
    • Girard, A.1    Sachidanandam, R.2    Hannon, G.J.3    Carmell, M.A.4
  • 46
    • 46249106990 scopus 로고    scopus 로고
    • Mapping and quantifying mammalian transcriptomes by RNA-Seq
    • DOI 10.1038/nmeth.1226, PII NMETH.1226
    • Mortazavi, A., Williams, B.A., McCue, K., Schaeffer, L. & Wold, B. Mapping and quantifying mammalian transcriptomes by RNA-Seq. Nat. Methods 5, 621-628 (2008). (Pubitemid 351911867)
    • (2008) Nature Methods , vol.5 , Issue.7 , pp. 621-628
    • Mortazavi, A.1    Williams, B.A.2    McCue, K.3    Schaeffer, L.4    Wold, B.5
  • 48
    • 80655142481 scopus 로고    scopus 로고
    • Hepg2 cells expressing microRNA miR-122 support the entire hepatitis C virus life cycle
    • Narbus, C.M. et al. HepG2 cells expressing microRNA miR-122 support the entire hepatitis C virus life cycle. J. Virol. 85, 12087-12092 (2011).
    • (2011) J. Virol , vol.85 , pp. 12087-12092
    • Narbus, C.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.