Identification of urinary miRNA biomarkers for detecting cisplatin-induced proximal tubular injury in rats

Toxicology

Volumn 324, Issue 1, 2014, Pages 158-168

  Kanki, Masayuki ^a   Moriguchi, Akira ^a   Sasaki, Daisuke ^a   Mitori, Hikaru ^a   Yamada, Atsushi ^a   Unami, Akira ^a   Miyamae, Yoichi ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

Biomarker; Cisplatin; MicroRNA; Nephrotoxicity; Urine

Indexed keywords

CISPLATIN; MICRORNA; MICRORNA 191A 5P; MICRORNA 192 5P; MICRORNA 93 5P; MICRORNA LET 7G 5P; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; CELL ADHESION MOLECULE; CLU PROTEIN, RAT; CLUSTERIN; CREATININE; HAVCR1PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE DAMAGE; MALE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT; URINALYSIS; ACUTE KIDNEY FAILURE; ANIMAL; BLOOD; CHEMICALLY INDUCED DISORDER; CLUSTER ANALYSIS; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENETIC MARKER; GENETICS; METABOLISM; METHODOLOGY; PATHOLOGY; SPRAGUE DAWLEY RAT; TIME; UREA NITROGEN BLOOD LEVEL; URINE;

RATTUS; RODENTIA;

BIOMARKER; CISPLATIN; MICRORNA; NEPHROTOXICITY; URINE;

ACUTE KIDNEY INJURY; ANIMALS; BLOOD UREA NITROGEN; CELL ADHESION MOLECULES; CISPLATIN; CLUSTER ANALYSIS; CLUSTERIN; CREATININE; GENE EXPRESSION PROFILING; GENETIC MARKERS; KIDNEY TUBULES, PROXIMAL; MALE; MICRORNAS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS; URINALYSIS;

EID: 84908260835     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2014.05.004     Document Type: Article

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