A microfluidic bioreactor with integrated transepithelial electrical resistance (TEER) measurement electrodes for evaluation of renal epithelial cells

Biotechnology and Bioengineering

Volumn 107, Issue 4, 2010, Pages 707-716

  Ferrell, Nicholas ^a   Desai, Ravi R ^b   Fleischman, Aaron J ^a   Roy, Shuvo ^c   Humes, H David ^d   Fissell, William H ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE   (United States)

^c San Francisco   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Bioreactor; Epithelial cells; Kidney; Microfluidics; Transepithelial electrical resistance

Indexed keywords

APICAL SURFACES; BEFORE AND AFTER; BI-LAYER; BIOREACTOR DESIGN; CELL LAYERS; CULTURE CONDITIONS; CYTOSKELETAL; CYTOSOLIC; EPITHELIAL CELLS; F-ACTIN; FLOW CONDITION; FLUID FLOW CONDITIONS; FLUIDIC CHAMBER; IMMUNOFLUORESCENCE STAINING; KIDNEY; KIDNEY EPITHELIAL CELL; MDCK CELLS; MICRO FLUIDIC SYSTEM; MICRO POROUS MEMBRANES; MICROFLUIDIC BIOREACTORS; MICROFLUIDIC CHANNEL; RENAL EPITHELIAL CELLS; STRESS FIBERS; TIGHT JUNCTIONS; TRACER MOLECULES; TRANSEPITHELIAL ELECTRICAL RESISTANCES; TRANSPORT PROCESS; TRANSPORT RATE;

BIOCONVERSION; BIOREACTORS; CELL CULTURE; ELECTRIC RESISTANCE; ELECTRODES; FLOW OF FLUIDS; FLUIDIC DEVICES; GROWTH KINETICS; LIVING SYSTEMS STUDIES; MICROFLUIDICS; PHYSIOLOGY;

CELLS;

ALPHA TUBULIN; F ACTIN; FLUORESCEIN ISOTHIOCYANATE; INULIN;

ARTICLE; BIOREACTOR; CELL GROWTH; CELL JUNCTION; CELL STRAIN; CELL SURFACE; CELL TRANSPORT; ELECTRIC RESISTANCE; ELECTRODE; EPITHELIUM CELL; FLUID FLOW; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; INTEGRATED TRANSEPITHELIAL ELECTRICAL RESISTANCE; KIDNEY CELL; LAMINAR FLOW; MICROFLUIDICS; SHEAR STRESS; STRESS FIBER;

ANIMALS; BIOREACTORS; CELL PROLIFERATION; DOGS; ELECTRIC IMPEDANCE; ELECTRODES; EPITHELIAL CELLS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MEMBRANE PROTEINS; MICROFLUIDIC ANALYTICAL TECHNIQUES; PHOSPHOPROTEINS; STAINING AND LABELING; TIGHT JUNCTIONS; TUBULIN;

EID: 78149338941     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.22835     Document Type: Article

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