A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents

Lab on a Chip

Volumn 15, Issue 12, 2015, Pages 2688-2699

  Maschmeyer, Ilka ^a,b   Lorenz, Alexandra K ^a,b   Schimek, Katharina ^a   Hasenberg, Tobias ^a,b   Ramme, Anja P ^a,b   Hübner, Juliane ^a   Lindner, Marcus ^a   Drewell, Christopher ^a   Bauer, Sophie ^a   Thomas, Alexander ^a   Sambo, Naomia Sisoli ^a   Sonntag, Frank ^c   Lauster, Roland ^a   Marx, Uwe ^a,b  

^a TECHNISCHE UNIVERSITÄT BERLIN   (Germany)

^b TISSUSE GMBH   (Germany)

^c FRAUNHOFER INSTITUTE FOR MATERIAL AND BEAM TECHNOLOGY IWS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL FUNCTION; CELL MEMBRANE; COCULTURE; CONTROLLED STUDY; DYNAMICS; ELECTRIC RESISTANCE; EPITHELIUM CELL; FLOW RATE; FLUID FLOW; FOUR ORGAN CHIP; GENE EXPRESSION; GENETIC TRANSCRIPTION; HOMEOSTASIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INTESTINE; INTESTINE EPITHELIUM CELL; KIDNEY; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; LAB ON A CHIP; LIVER; LIVER FUNCTION; LIVER LOBULE; MICROFLUIDICS; MONOLAYER CULTURE; POLYMERIZATION; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RESIDUAL VOLUME; SHEAR STRESS; SKIN; SKIN BIOPSY; STEADY STATE; STELLATE CELL; TIGHT JUNCTION; TRANSEPITHELIAL ELECTRICAL RESISTANCE; UPREGULATION; BIOLOGICAL MODEL; CELL CULTURE; CELL LINE; CYTOLOGY; DEVICES; EQUIPMENT DESIGN; GENE EXPRESSION PROFILING; METABOLISM; MICROFLUIDIC ANALYSIS; PROCEDURES; TOXICITY TESTING;

CELL LINE; CELLS, CULTURED; COCULTURE TECHNIQUES; EQUIPMENT DESIGN; GENE EXPRESSION PROFILING; HUMANS; KIDNEY; LIVER; MICROFLUIDIC ANALYTICAL TECHNIQUES; MODELS, BIOLOGICAL; SKIN; TOXICITY TESTS;

EID: 84930959624     PISSN: 14730197     EISSN: 14730189     Source Type: Journal    
DOI: 10.1039/c5lc00392j     Document Type: Article

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