Application of RPTEC/TERT1 cells for investigation of repeat dose nephrotoxicity: A transcriptomic study

Toxicology in Vitro

Volumn 30, Issue 1, 2015, Pages 106-116

  Aschauer, Lydia ^a   Limonciel, Alice ^a   Wilmes, Anja ^a   Stanzel, Sven ^b   Kopp Schneider, Annette ^b   Hewitt, Philip ^c   Lukas, Arno ^d   Leonard, Martin O ^e   Pfaller, Walter ^a   Jennings, Paul ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c Merck Serono GmbH   (Germany)

^d Emergentec Biodevelopment GmbH   (Austria)

^e PUBLIC HEALTH ENGLAND   (United Kingdom)

Author keywords

Nephrotoxin; Proximal tubule; RPTEC TERT1; Stress response; Transcriptomics

Indexed keywords

ADEFOVIR DIPIVOXIL; CADMIUM CHLORIDE; CHLOROACETALDEHYDE; CIDOFOVIR; CISPLATIN; CLODRONIC ACID; CYCLOSPORIN A; IFOSFAMIDE; LACTIC ACID; ZOLEDRONIC ACID; DRUG; LACTIC ACID DERIVATIVE; TRANSCRIPTOME;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; ELECTRIC RESISTANCE; HUMAN; HUMAN CELL; HYPOXIA; KIDNEY CELL; KIDNEY PROXIMAL TUBULE; NEPHROTOXICITY; REPEATED DRUG DOSE; SUPERNATANT; TRANSCRIPTOMICS; CELL CULTURE TECHNIQUE; CELL LINE; CHEMICALLY INDUCED; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; IMPEDANCE; KIDNEY DISEASE; METABOLISM;

CELL CULTURE TECHNIQUES; CELL LINE; ELECTRIC IMPEDANCE; GENE EXPRESSION REGULATION; HUMANS; KIDNEY DISEASES; KIDNEY TUBULES, PROXIMAL; LACTATES; PHARMACEUTICAL PREPARATIONS; TRANSCRIPTOME;

EID: 84919625742     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2014.10.005     Document Type: Article

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