Mouse models of human TB pathology: roles in the analysis of necrosis and the development of host-directed therapies

Seminars in Immunopathology

Volumn 38, Issue 2, 2016, Pages 221-237

  Kramnik, Igor ^a   Beamer, Gillian ^b  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TUFTS UNIVERSITY   (United States)

Author keywords

Animal models; Granuloma; Host directed therapies; Inbred mice; Mechanisms; Necrosis; sst1; Tuberculosis

Indexed keywords

BACTERIAL STRAIN; BACTERIAL TRANSMISSION; CAUSAL ATTRIBUTION; GENE LOCUS; GENETIC HETEROGENEITY; GENETIC VARIABILITY; GRANULOMA; HUMAN; LUNG DISEASE; LUNG TUBERCULOSIS; MACROPHAGE; MOUSE MODEL; MYCOBACTERIUM TUBERCULOSIS; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PULMONARY NECROSIS; REGULATOR GENE; REVIEW; SST1 GENE; ANIMAL; DISEASE MODEL; DRUG EFFECTS; GENETIC PREDISPOSITION; GENETIC VARIATION; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; MOUSE; NECROSIS; PATHOLOGY; PHYSIOLOGY; TUBERCULOSIS;

SOMATOSTATIN RECEPTOR; SOMATOSTATIN RECEPTOR 1, MOUSE; TUBERCULOSTATIC AGENT;

ANIMALS; ANTITUBERCULAR AGENTS; DISEASE MODELS, ANIMAL; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GRANULOMA; HOST-PATHOGEN INTERACTIONS; HUMANS; MACROPHAGES; MICE; MYCOBACTERIUM TUBERCULOSIS; NECROSIS; NEUTROPHILS; RECEPTORS, SOMATOSTATIN; TUBERCULOSIS;

EID: 84959529153     PISSN: 18632297     EISSN: 18632300     Source Type: Journal    
DOI: 10.1007/s00281-015-0538-9     Document Type: Review

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