Ipr1 gene mediates innate immunity to tuberculosis

Nature

Volumn 434, Issue 7034, 2005, Pages 767-772

  Pan, Hui ^a   Yan, Bo Shiun ^a   Rojas, Mauricio ^a,b   Shebzukhov, Yuriy V ^a,e   Zhou, Hongwei ^a   Kobzik, Lester ^a   Higgins, Darren E ^c   Daly, Mark J ^d   Bloom, Barry R ^a   Kramnik, Igor ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b UNIVERSIDAD DE ANTIOQUIA   (Colombia)

^c HARVARD MEDICAL SCHOOL   (United States)

^d WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^e MOSCOW STATE UNIVERSITY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMOSOMES; GENES; HUMAN ENGINEERING; PATHOLOGY;

CONGENIC MOUSE STRAINS; GENETIC VARIATION; INTRACELLULAR PATHOGEN RESISTANCE 1 (IPR1); MOUSE CHROMOSOME 1; PATHOGEN MYCOBACTERIUM TUBERCULOSIS;

GENETIC ENGINEERING;

GENE PRODUCT; GAMMA INTERFERON; IFI75 PROTEIN, MOUSE; MESSENGER RNA; NUCLEAR PROTEIN; SP110 PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BACTERIAL GROWTH; BACTERIAL IMMUNITY; CHROMOSOME 1; GENE; GENE EXPRESSION; GENE IDENTIFICATION; GENE LOCUS; GENE MAPPING; GENETIC VARIABILITY; HOST PATHOGEN INTERACTION; HOST RESISTANCE; IPR1 GENE; LISTERIA MONOCYTOGENES; MACROPHAGE ACTIVATION; MALE; MORTALITY; MOUSE; MOUSE STRAIN; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SST1 GENE; TUBERCULOSIS; ANIMAL; BONE MARROW TRANSPLANTATION; C3H MOUSE; C57BL MOUSE; CHEMISTRY; CONGENIC STRAIN; DISEASE COURSE; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; HUMAN; IMMUNOLOGY; INNATE IMMUNITY; LUNG; MACROPHAGE; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS; NECROSIS; PATHOGENICITY; PATHOLOGY; SURVIVAL RATE; TRANSGENE;

ANIMALIA; LISTERIA MONOCYTOGENES; MYCOBACTERIUM TUBERCULOSIS;

ANIMALS; ANIMALS, CONGENIC; APOPTOSIS; BONE MARROW TRANSPLANTATION; DISEASE PROGRESSION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; IMMUNITY, NATURAL; INTERFERON TYPE II; LISTERIA MONOCYTOGENES; LUNG; MACROPHAGES; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM TUBERCULOSIS; NECROSIS; NUCLEAR PROTEINS; POLYMORPHISM, GENETIC; RNA, MESSENGER; SURVIVAL RATE; TRANS-ACTIVATORS; TRANSGENES; TUBERCULOSIS;

EID: 17144386211     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature03419     Document Type: Article

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