메뉴 건너뛰기




Volumn 264, Issue 1, 2015, Pages 288-307

Heterogeneity in tuberculosis pathology, microenvironments and therapeutic responses

Author keywords

Animal models; Biomarkers; Immunopathology; Lesion dynamics; Tuberculosis

Indexed keywords

LINEZOLID; TUBERCULOSTATIC AGENT;

EID: 84923172431     PISSN: 01052896     EISSN: 1600065X     Source Type: Journal    
DOI: 10.1111/imr.12252     Document Type: Article
Times cited : (261)

References (143)
  • 2
    • 0242702965 scopus 로고
    • New York: Springer Publishing COmpany
    • Canetti G. The Tubercle Bacillus. New York: Springer Publishing COmpany, 1955.
    • (1955) The Tubercle Bacillus
    • Canetti, G.1
  • 4
    • 84864386253 scopus 로고    scopus 로고
    • Infection dynamics and response to chemotherapy in a Rabbit model of tuberculosis using (18F)2-fluoro-deoxy-D-glucose positron emission tomography and computed tomography
    • Via LE, et al. Infection dynamics and response to chemotherapy in a Rabbit model of tuberculosis using (18F)2-fluoro-deoxy-D-glucose positron emission tomography and computed tomography. Antimicrob Agents Chemother 2012;56:4391-4402.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 4391-4402
    • Via, L.E.1
  • 5
    • 84880664059 scopus 로고    scopus 로고
    • Differential virulence and disease progression following Mycobacterium tuberculosis complex infection of the common marmoset (Callithrix jacchus)
    • Via LE, et al. Differential virulence and disease progression following Mycobacterium tuberculosis complex infection of the common marmoset (Callithrix jacchus). Infect Immun 2013;81:2909-2919.
    • (2013) Infect Immun , vol.81 , pp. 2909-2919
    • Via, L.E.1
  • 6
    • 84881257487 scopus 로고    scopus 로고
    • A computational pipeline for quantification of pulmonary infections in small animal models using serial PET-CT imaging
    • Bagci U, et al. A computational pipeline for quantification of pulmonary infections in small animal models using serial PET-CT imaging. EJNMMI Res 2013;3:55.
    • (2013) EJNMMI Res , vol.3 , pp. 55
    • Bagci, U.1
  • 7
    • 84907559655 scopus 로고    scopus 로고
    • Imaging the evolution of reactivation pulmonary tuberculosis in mice using 18F-FDG PET
    • Murawski AM, et al. Imaging the evolution of reactivation pulmonary tuberculosis in mice using 18F-FDG PET. J Nucl Med 2014. doi: 10.2967/jnumed.114.144634.
    • (2014) J Nucl Med
    • Murawski, A.M.1
  • 8
    • 84900317225 scopus 로고    scopus 로고
    • The ongoing challenge of latent tuberculosis
    • Esmail H, et al. The ongoing challenge of latent tuberculosis. Philos Trans R Soc Lond B Biol Sci 2014;369:20130437.
    • (2014) Philos Trans R Soc Lond B Biol Sci , vol.369 , pp. 20130437
    • Esmail, H.1
  • 9
    • 78349263110 scopus 로고    scopus 로고
    • Changing concepts of "latent tuberculosis infection" in patients living with HIV infection
    • Lawn SD, Wood R, Wilkinson RJ. Changing concepts of "latent tuberculosis infection" in patients living with HIV infection. Clin Dev Immunol 2011;2011. doi: 10.1155/2011/980594.
    • (2011) Clin Dev Immunol , vol.2011
    • Lawn, S.D.1    Wood, R.2    Wilkinson, R.J.3
  • 10
    • 70449705831 scopus 로고    scopus 로고
    • The spectrum of latent tuberculosis: rethinking the biology and intervention strategies
    • Barry CER, et al. The spectrum of latent tuberculosis: rethinking the biology and intervention strategies. Nat Rev Microbiol 2009;7:845-855.
    • (2009) Nat Rev Microbiol , vol.7 , pp. 845-855
    • Barry, C.E.R.1
  • 12
    • 0141669013 scopus 로고    scopus 로고
    • Experimental Mycobacterium tuberculosis infection of cynomolgus macaques closely resembles the various manifestations of human M. tuberculosis infection
    • Capuano SV 3rd, et al. Experimental Mycobacterium tuberculosis infection of cynomolgus macaques closely resembles the various manifestations of human M. tuberculosis infection. Infect Immun 2003;71:5831-5844.
    • (2003) Infect Immun , vol.71 , pp. 5831-5844
    • Capuano, S.V.1
  • 13
    • 70349427123 scopus 로고    scopus 로고
    • Quantitative comparison of active and latent tuberculosis in the cynomolgus macaque model
    • Lin PL, et al. Quantitative comparison of active and latent tuberculosis in the cynomolgus macaque model. Infect Immun 2009;77:4631-4642.
    • (2009) Infect Immun , vol.77 , pp. 4631-4642
    • Lin, P.L.1
  • 14
    • 77955894773 scopus 로고    scopus 로고
    • An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis
    • Berry MP, et al. An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis. Nature 2010;466:973-977.
    • (2010) Nature , vol.466 , pp. 973-977
    • Berry, M.P.1
  • 15
    • 84881104975 scopus 로고    scopus 로고
    • Transcriptional blood signatures distinguish pulmonary tuberculosis, pulmonary sarcoidosis, pneumonias and lung cancers
    • Bloom CI, et al. Transcriptional blood signatures distinguish pulmonary tuberculosis, pulmonary sarcoidosis, pneumonias and lung cancers. PLoS ONE 2013;8:e70630.
    • (2013) PLoS ONE , vol.8 , pp. e70630
    • Bloom, C.I.1
  • 16
    • 84867614599 scopus 로고    scopus 로고
    • Linezolid for treatment of chronic extensively drug-resistant tuberculosis
    • Lee M, et al. Linezolid for treatment of chronic extensively drug-resistant tuberculosis. N Engl J Med 2012;367:1508-1518.
    • (2012) N Engl J Med , vol.367 , pp. 1508-1518
    • Lee, M.1
  • 17
    • 84915818775 scopus 로고    scopus 로고
    • PET/CT monitoring demonstrates a therapeutic response to oxazolidinones in Mycobacterium tuberculosis infected macaques and humans
    • 265ra167
    • Coleman MT, et al. PET/CT monitoring demonstrates a therapeutic response to oxazolidinones in Mycobacterium tuberculosis infected macaques and humans. Sci Transl Med 2014;6:265ra167.
    • (2014) Sci Transl Med , vol.6
    • Coleman, M.T.1
  • 18
    • 0018203895 scopus 로고
    • Short term chemotherapy of tuberculosis. Factors affecting relapse following short term chemotherapy
    • Aber VR, Nunn AJ. Short term chemotherapy of tuberculosis. Factors affecting relapse following short term chemotherapy. Bull Int Union Tuberc 1978;53:276-280.
    • (1978) Bull Int Union Tuberc , vol.53 , pp. 276-280
    • Aber, V.R.1    Nunn, A.J.2
  • 19
    • 8444222775 scopus 로고    scopus 로고
    • A nested case-control study on treatment-related risk factors for early relapse of tuberculosis
    • Chang KC, et al. A nested case-control study on treatment-related risk factors for early relapse of tuberculosis. Am J Respir Crit Care Med 2004;170:1124-1130.
    • (2004) Am J Respir Crit Care Med , vol.170 , pp. 1124-1130
    • Chang, K.C.1
  • 20
    • 0037125569 scopus 로고    scopus 로고
    • Rifapentine and isoniazid once a week versus rifampicin and isoniazid twice a week for treatment of drug-susceptible pulmonary tuberculosis in HIV-negative patients: a randomised clinical trial
    • Benator D, et al. Rifapentine and isoniazid once a week versus rifampicin and isoniazid twice a week for treatment of drug-susceptible pulmonary tuberculosis in HIV-negative patients: a randomised clinical trial. Lancet 2002;360:528-534.
    • (2002) Lancet , vol.360 , pp. 528-534
    • Benator, D.1
  • 21
    • 0034682516 scopus 로고    scopus 로고
    • Genetic control of resistance to experimental infection with virulent Mycobacterium tuberculosis
    • Kramnik I, et al. Genetic control of resistance to experimental infection with virulent Mycobacterium tuberculosis. Proc Natl Acad Sci USA 2000;97:8560-8565.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 8560-8565
    • Kramnik, I.1
  • 22
    • 84861163743 scopus 로고    scopus 로고
    • Evaluation of a mouse model of necrotic granuloma formation using C3HeB/FeJ mice for testing of drugs against Mycobacterium tuberculosis
    • Driver ER, et al. Evaluation of a mouse model of necrotic granuloma formation using C3HeB/FeJ mice for testing of drugs against Mycobacterium tuberculosis. Antimicrob Agents Chemother 2012;56:3181-3195.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 3181-3195
    • Driver, E.R.1
  • 23
    • 70350322939 scopus 로고    scopus 로고
    • Noninvasive pulmonary (18F)-2-fluoro-deoxy-D-glucose positron emission tomography correlates with bactericidal activity of tuberculosis drug treatment
    • Davis SL, et al. Noninvasive pulmonary (18F)-2-fluoro-deoxy-D-glucose positron emission tomography correlates with bactericidal activity of tuberculosis drug treatment. Antimicrob Agents Chemother 2009;53:4879-4884.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 4879-4884
    • Davis, S.L.1
  • 24
    • 84903188913 scopus 로고    scopus 로고
    • Limited activity of clofazimine as a single drug in a mouse model of tuberculosis exhibiting caseous necrotic granulomas
    • Irwin SM, et al. Limited activity of clofazimine as a single drug in a mouse model of tuberculosis exhibiting caseous necrotic granulomas. Antimicrob Agents Chemother 2014;58:4026-4034.
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 4026-4034
    • Irwin, S.M.1
  • 25
    • 84862980932 scopus 로고    scopus 로고
    • Adjunctive TNF inhibition with standard treatment enhances bacterial clearance in a murine model of necrotic TB granulomas
    • Skerry C, et al. Adjunctive TNF inhibition with standard treatment enhances bacterial clearance in a murine model of necrotic TB granulomas. PLoS ONE 2012;7:e39680.
    • (2012) PLoS ONE , vol.7 , pp. e39680
    • Skerry, C.1
  • 26
    • 84879405292 scopus 로고    scopus 로고
    • Ibuprofen therapy resulted in significantly decreased tissue bacillary loads and increased survival in a new murine experimental model of active tuberculosis
    • Vilaplana C, et al. Ibuprofen therapy resulted in significantly decreased tissue bacillary loads and increased survival in a new murine experimental model of active tuberculosis. J Infect Dis 2013;208:199-202.
    • (2013) J Infect Dis , vol.208 , pp. 199-202
    • Vilaplana, C.1
  • 27
    • 84891555267 scopus 로고    scopus 로고
    • Damaging role of neutrophilic infiltration in a mouse model of progressive tuberculosis
    • Marzo E, et al. Damaging role of neutrophilic infiltration in a mouse model of progressive tuberculosis. Tuberculosis 2014;94:55-64.
    • (2014) Tuberculosis , vol.94 , pp. 55-64
    • Marzo, E.1
  • 28
    • 84891418361 scopus 로고    scopus 로고
    • Gr1(int)CD11b+ myeloid-derived suppressor cells in Mycobacterium tuberculosis infection
    • Obregon-Henao A, et al. Gr1(int)CD11b+ myeloid-derived suppressor cells in Mycobacterium tuberculosis infection. PLoS ONE 2013;8:e80669.
    • (2013) PLoS ONE , vol.8 , pp. e80669
    • Obregon-Henao, A.1
  • 29
    • 75749099727 scopus 로고    scopus 로고
    • Tumor necrosis factor neutralization results in disseminated disease in acute and latent Mycobacterium tuberculosis infection with normal granuloma structure in a cynomolgus macaque model
    • Lin PL, et al. Tumor necrosis factor neutralization results in disseminated disease in acute and latent Mycobacterium tuberculosis infection with normal granuloma structure in a cynomolgus macaque model. Arthritis Rheum 2010;62:340-350.
    • (2010) Arthritis Rheum , vol.62 , pp. 340-350
    • Lin, P.L.1
  • 30
    • 84882427707 scopus 로고    scopus 로고
    • Radiologic responses in cynomolgous macaques for assessing tuberculosis chemotherapy regimens
    • Lin PL, et al. Radiologic responses in cynomolgous macaques for assessing tuberculosis chemotherapy regimens. Antimicrob Agents Chemother 2013;57:4237-4244.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 4237-4244
    • Lin, P.L.1
  • 31
    • 77955294740 scopus 로고    scopus 로고
    • Establishment of an aerosol challenge model of tuberculosis in rhesus macaques and an evaluation of endpoints for vaccine testing
    • Sharpe SA, et al. Establishment of an aerosol challenge model of tuberculosis in rhesus macaques and an evaluation of endpoints for vaccine testing. Clin Vaccine Immunol 2010;17:1170-1182.
    • (2010) Clin Vaccine Immunol , vol.17 , pp. 1170-1182
    • Sharpe, S.A.1
  • 32
    • 84905986952 scopus 로고    scopus 로고
    • Aerosol vaccination with AERAS-402 elicits robust cellular immune responses in the lungs of rhesus macaques but fails to protect against high-dose Mycobacterium tuberculosis challenge
    • Darrah PA, et al. Aerosol vaccination with AERAS-402 elicits robust cellular immune responses in the lungs of rhesus macaques but fails to protect against high-dose Mycobacterium tuberculosis challenge. J Immunol 2014;193:1799-1811.
    • (2014) J Immunol , vol.193 , pp. 1799-1811
    • Darrah, P.A.1
  • 33
    • 0141668958 scopus 로고    scopus 로고
    • Different strains of Mycobacterium tuberculosis cause various spectrums of disease in the rabbit model of tuberculosis
    • Manabe YC, et al. Different strains of Mycobacterium tuberculosis cause various spectrums of disease in the rabbit model of tuberculosis. Infect Immun 2003;71:6004-6011.
    • (2003) Infect Immun , vol.71 , pp. 6004-6011
    • Manabe, Y.C.1
  • 34
    • 43049159478 scopus 로고    scopus 로고
    • The aerosol rabbit model of TB latency, reactivation and immune reconstitution inflammatory syndrome
    • Manabe YC, et al. The aerosol rabbit model of TB latency, reactivation and immune reconstitution inflammatory syndrome. Tuberculosis 2008;88:187-196.
    • (2008) Tuberculosis , vol.88 , pp. 187-196
    • Manabe, Y.C.1
  • 35
    • 84868130200 scopus 로고    scopus 로고
    • Spontaneous latency in a rabbit model of pulmonary tuberculosis
    • Subbian S, et al. Spontaneous latency in a rabbit model of pulmonary tuberculosis. Am J Pathol 2012;181:1711-1724.
    • (2012) Am J Pathol , vol.181 , pp. 1711-1724
    • Subbian, S.1
  • 36
    • 84863225190 scopus 로고    scopus 로고
    • Chronic pulmonary cavitary tuberculosis in rabbits: a failed host immune response
    • Subbian S, et al. Chronic pulmonary cavitary tuberculosis in rabbits: a failed host immune response. Open Biol 2011;1:110016. doi: 10.1098/rsob.110016.
    • (2011) Open Biol , vol.1 , pp. 110016
    • Subbian, S.1
  • 37
    • 84455169868 scopus 로고    scopus 로고
    • Pharmacokinetic evaluation of the penetration of antituberculosis agents in rabbit pulmonary lesions
    • Kjellsson MC, et al. Pharmacokinetic evaluation of the penetration of antituberculosis agents in rabbit pulmonary lesions. Antimicrob Agents Chemother 2012;56:446-457.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 446-457
    • Kjellsson, M.C.1
  • 38
    • 84891853921 scopus 로고    scopus 로고
    • Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing
    • Lin PL, et al. Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing. Nat Med 2014;20:75-79.
    • (2014) Nat Med , vol.20 , pp. 75-79
    • Lin, P.L.1
  • 39
  • 40
    • 84903750131 scopus 로고    scopus 로고
    • Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk
    • Mayer-Barber KD, et al. Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk. Nature 2014;511:99-103.
    • (2014) Nature , vol.511 , pp. 99-103
    • Mayer-Barber, K.D.1
  • 41
    • 77955661920 scopus 로고    scopus 로고
    • Evasion of innate immunity by Mycobacterium tuberculosis: is death an exit strategy?
    • Behar SM, Divangahi M, Remold HG. Evasion of innate immunity by Mycobacterium tuberculosis: is death an exit strategy? Nat Rev Microbiol 2010;8:668-674.
    • (2010) Nat Rev Microbiol , vol.8 , pp. 668-674
    • Behar, S.M.1    Divangahi, M.2    Remold, H.G.3
  • 42
    • 77649128120 scopus 로고    scopus 로고
    • The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans
    • Tobin DM, et al. The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans. Cell 2010;140:717-730.
    • (2010) Cell , vol.140 , pp. 717-730
    • Tobin, D.M.1
  • 43
    • 84856693171 scopus 로고    scopus 로고
    • Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections
    • Tobin DM, et al. Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections. Cell 2012;148:434-446.
    • (2012) Cell , vol.148 , pp. 434-446
    • Tobin, D.M.1
  • 44
    • 84856755460 scopus 로고    scopus 로고
    • Innate immunity to TB: a druggable balancing act
    • Lalvani A, Behr MA, Sridhar S. Innate immunity to TB: a druggable balancing act. Cell 2012;148:389-391.
    • (2012) Cell , vol.148 , pp. 389-391
    • Lalvani, A.1    Behr, M.A.2    Sridhar, S.3
  • 45
    • 84880126124 scopus 로고    scopus 로고
    • Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase isoforms
    • Mattila JT, et al. Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase isoforms. J Immunol 2013;191:773-784.
    • (2013) J Immunol , vol.191 , pp. 773-784
    • Mattila, J.T.1
  • 46
    • 84882470985 scopus 로고    scopus 로고
    • Early innate immunity determines outcome of Mycobacterium tuberculosis pulmonary infection in rabbits
    • Subbian S, et al. Early innate immunity determines outcome of Mycobacterium tuberculosis pulmonary infection in rabbits. Cell Commun Signal 2013;11:60.
    • (2013) Cell Commun Signal , vol.11 , pp. 60
    • Subbian, S.1
  • 47
    • 67349164282 scopus 로고    scopus 로고
    • Clinical strains of Mycobacterium tuberculosis display a wide range of virulence in guinea pigs
    • Palanisamy GS, et al. Clinical strains of Mycobacterium tuberculosis display a wide range of virulence in guinea pigs. Tuberculosis 2009;89:203-209.
    • (2009) Tuberculosis , vol.89 , pp. 203-209
    • Palanisamy, G.S.1
  • 48
    • 4544298326 scopus 로고    scopus 로고
    • A glycolipid of hypervirulent tuberculosis strains that inhibits the innate immune response
    • Reed MB, et al. A glycolipid of hypervirulent tuberculosis strains that inhibits the innate immune response. Nature 2004;431:84-87.
    • (2004) Nature , vol.431 , pp. 84-87
    • Reed, M.B.1
  • 49
    • 34447126847 scopus 로고    scopus 로고
    • Neutrophil-mediated innate immune resistance to mycobacteria
    • Martineau AR, et al. Neutrophil-mediated innate immune resistance to mycobacteria. J Clin Invest 2007;117:1988-1994.
    • (2007) J Clin Invest , vol.117 , pp. 1988-1994
    • Martineau, A.R.1
  • 50
    • 0023792682 scopus 로고
    • Predictors of short-term prognosis in patients with pulmonary tuberculosis
    • Barnes PF, et al. Predictors of short-term prognosis in patients with pulmonary tuberculosis. J Infect Dis 1988;158:366-371.
    • (1988) J Infect Dis , vol.158 , pp. 366-371
    • Barnes, P.F.1
  • 51
    • 84890062410 scopus 로고    scopus 로고
    • Neutrophilia independently predicts death in tuberculosis
    • Lowe DM, et al. Neutrophilia independently predicts death in tuberculosis. Eur Respir J 2013;42:1752-1757.
    • (2013) Eur Respir J , vol.42 , pp. 1752-1757
    • Lowe, D.M.1
  • 52
    • 0031947095 scopus 로고    scopus 로고
    • Local immune responses correlate with presentation and outcome in tuberculosis
    • Condos R, et al. Local immune responses correlate with presentation and outcome in tuberculosis. Am J Respir Crit Care Med 1998;157(3 Pt 1):729-735.
    • (1998) Am J Respir Crit Care Med , vol.157 , Issue.3 , pp. 729-735
    • Condos, R.1
  • 53
    • 74949135138 scopus 로고    scopus 로고
    • Neutrophils are the predominant infected phagocytic cells in the airways of patients with active pulmonary TB
    • Eum SY, et al. Neutrophils are the predominant infected phagocytic cells in the airways of patients with active pulmonary TB. Chest 2010;137:122-128.
    • (2010) Chest , vol.137 , pp. 122-128
    • Eum, S.Y.1
  • 54
    • 84855333428 scopus 로고    scopus 로고
    • Neutrophils in tuberculosis: friend or foe?
    • Lowe DM, et al. Neutrophils in tuberculosis: friend or foe? Trends Immunol 2012;33:14-25.
    • (2012) Trends Immunol , vol.33 , pp. 14-25
    • Lowe, D.M.1
  • 55
    • 84862565266 scopus 로고    scopus 로고
    • Escape of Mycobacterium tuberculosis from oxidative killing by neutrophils
    • Corleis B, et al. Escape of Mycobacterium tuberculosis from oxidative killing by neutrophils. Cell Microbiol 2012;14:1109-1121.
    • (2012) Cell Microbiol , vol.14 , pp. 1109-1121
    • Corleis, B.1
  • 56
    • 84875442814 scopus 로고    scopus 로고
    • Neutrophil recruitment and function in health and inflammation
    • Kolaczkowska E, Kubes P. Neutrophil recruitment and function in health and inflammation. Nat Rev Immunol 2013;13:159-175.
    • (2013) Nat Rev Immunol , vol.13 , pp. 159-175
    • Kolaczkowska, E.1    Kubes, P.2
  • 57
    • 4143115478 scopus 로고    scopus 로고
    • Three different neutrophil subsets exhibited in mice with different susceptibilities to infection by methicillin-resistant Staphylococcus aureus
    • Tsuda Y, et al. Three different neutrophil subsets exhibited in mice with different susceptibilities to infection by methicillin-resistant Staphylococcus aureus. Immunity 2004;21:215-226.
    • (2004) Immunity , vol.21 , pp. 215-226
    • Tsuda, Y.1
  • 58
    • 80055109822 scopus 로고    scopus 로고
    • Regulation of neutrophils by interferon-gamma limits lung inflammation during tuberculosis infection
    • Nandi B, Behar SM. Regulation of neutrophils by interferon-gamma limits lung inflammation during tuberculosis infection. J Exp Med 2011;208:2251-2262.
    • (2011) J Exp Med , vol.208 , pp. 2251-2262
    • Nandi, B.1    Behar, S.M.2
  • 59
    • 84864357703 scopus 로고    scopus 로고
    • The immunological life cycle of tuberculosis
    • Ernst JD. The immunological life cycle of tuberculosis. Nat Rev Immunol 2012;12:581-591.
    • (2012) Nat Rev Immunol , vol.12 , pp. 581-591
    • Ernst, J.D.1
  • 60
    • 84891561583 scopus 로고    scopus 로고
    • A new unifying theory of the pathogenesis of tuberculosis
    • Orme IM. A new unifying theory of the pathogenesis of tuberculosis. Tuberculosis 2014;94:8-14.
    • (2014) Tuberculosis , vol.94 , pp. 8-14
    • Orme, I.M.1
  • 61
    • 20244371528 scopus 로고    scopus 로고
    • Modified immunohistological staining allows detection of Ziehl-Neelsen-negative Mycobacterium tuberculosis organisms and their precise localization in human tissue
    • Ulrichs T, et al. Modified immunohistological staining allows detection of Ziehl-Neelsen-negative Mycobacterium tuberculosis organisms and their precise localization in human tissue. J Pathol 2005;205:633-640.
    • (2005) J Pathol , vol.205 , pp. 633-640
    • Ulrichs, T.1
  • 62
    • 67650655950 scopus 로고    scopus 로고
    • A novel in vitro multiple-stress dormancy model for Mycobacterium tuberculosis generates a lipid-loaded, drug-tolerant, dormant pathogen
    • Deb C, et al. A novel in vitro multiple-stress dormancy model for Mycobacterium tuberculosis generates a lipid-loaded, drug-tolerant, dormant pathogen. PLoS ONE 2009;4:e6077.
    • (2009) PLoS ONE , vol.4 , pp. e6077
    • Deb, C.1
  • 63
    • 34247572374 scopus 로고    scopus 로고
    • Deletion of kasB in Mycobacterium tuberculosis causes loss of acid-fastness and subclinical latent tuberculosis in immunocompetent mice
    • Bhatt A, et al. Deletion of kasB in Mycobacterium tuberculosis causes loss of acid-fastness and subclinical latent tuberculosis in immunocompetent mice. Proc Natl Acad Sci USA 2007;104:5157-5162.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 5157-5162
    • Bhatt, A.1
  • 64
    • 0031694056 scopus 로고    scopus 로고
    • The effect of oxygenated mycolic acid composition on cell wall function and macrophage growth in Mycobacterium tuberculosis
    • Yuan Y, et al. The effect of oxygenated mycolic acid composition on cell wall function and macrophage growth in Mycobacterium tuberculosis. Mol Microbiol 1998;29:1449-1458.
    • (1998) Mol Microbiol , vol.29 , pp. 1449-1458
    • Yuan, Y.1
  • 65
    • 0242552007 scopus 로고    scopus 로고
    • Cell-wall alterations as an attribute of Mycobacterium tuberculosis in latent infection
    • Seiler P, et al. Cell-wall alterations as an attribute of Mycobacterium tuberculosis in latent infection. J Infect Dis 2003;188:1326-1331.
    • (2003) J Infect Dis , vol.188 , pp. 1326-1331
    • Seiler, P.1
  • 66
    • 77956213734 scopus 로고    scopus 로고
    • Multiple M. tuberculosis phenotypes in mouse and guinea pig lung tissue revealed by a dual-staining approach
    • Ryan GJ, et al. Multiple M. tuberculosis phenotypes in mouse and guinea pig lung tissue revealed by a dual-staining approach. PLoS ONE 2010;5:e11108.
    • (2010) PLoS ONE , vol.5 , pp. e11108
    • Ryan, G.J.1
  • 67
    • 33747603012 scopus 로고    scopus 로고
    • Fluorescence versus conventional sputum smear microscopy for tuberculosis: a systematic review
    • Steingart KR, et al. Fluorescence versus conventional sputum smear microscopy for tuberculosis: a systematic review. Lancet Infect Dis 2006;6:570-581.
    • (2006) Lancet Infect Dis , vol.6 , pp. 570-581
    • Steingart, K.R.1
  • 68
    • 84908138044 scopus 로고    scopus 로고
    • Improving acid-fast fluorescent staining for the detection of mycobacteria using a new nucleic acid staining approach
    • Ryan GJ, Shapiro HM, Lenaerts AJ. Improving acid-fast fluorescent staining for the detection of mycobacteria using a new nucleic acid staining approach. Tuberculosis 2014;94:511-518.
    • (2014) Tuberculosis , vol.94 , pp. 511-518
    • Ryan, G.J.1    Shapiro, H.M.2    Lenaerts, A.J.3
  • 69
    • 11144339323 scopus 로고    scopus 로고
    • Replication dynamics of Mycobacterium tuberculosis in chronically infected mice
    • Munoz-Elias EJ, et al. Replication dynamics of Mycobacterium tuberculosis in chronically infected mice. Infect Immun 2005;73:546-551.
    • (2005) Infect Immun , vol.73 , pp. 546-551
    • Munoz-Elias, E.J.1
  • 70
    • 84880506145 scopus 로고    scopus 로고
    • The Mycobacterium tuberculosis regulatory network and hypoxia
    • Galagan JE, et al. The Mycobacterium tuberculosis regulatory network and hypoxia. Nature 2013;499:178-183.
    • (2013) Nature , vol.499 , pp. 178-183
    • Galagan, J.E.1
  • 71
    • 0034780485 scopus 로고    scopus 로고
    • Nonreplicating persistence of mycobacterium tuberculosis
    • Wayne LG, Sohaskey CD. Nonreplicating persistence of mycobacterium tuberculosis. Annu Rev Microbiol 2001;55:139-163.
    • (2001) Annu Rev Microbiol , vol.55 , pp. 139-163
    • Wayne, L.G.1    Sohaskey, C.D.2
  • 72
    • 84858955831 scopus 로고    scopus 로고
    • How Mycobacterium tuberculosis goes to sleep: the dormancy survival regulator DosR a decade later
    • Boon C, Dick T. How Mycobacterium tuberculosis goes to sleep: the dormancy survival regulator DosR a decade later. Future Microbiol 2012;7:513-518.
    • (2012) Future Microbiol , vol.7 , pp. 513-518
    • Boon, C.1    Dick, T.2
  • 73
    • 33644832153 scopus 로고    scopus 로고
    • Characterization of the tuberculous granuloma in murine and human lungs: cellular composition and relative tissue oxygen tension
    • Tsai MC, et al. Characterization of the tuberculous granuloma in murine and human lungs: cellular composition and relative tissue oxygen tension. Cell Microbiol 2006;8:218-232.
    • (2006) Cell Microbiol , vol.8 , pp. 218-232
    • Tsai, M.C.1
  • 74
    • 46249108568 scopus 로고    scopus 로고
    • Tuberculous granulomas are hypoxic in guinea pigs, rabbits, and non-human primates
    • Via LE, et al. Tuberculous granulomas are hypoxic in guinea pigs, rabbits, and non-human primates. Infect Immun 2008;76:2333-2340.
    • (2008) Infect Immun , vol.76 , pp. 2333-2340
    • Via, L.E.1
  • 75
    • 33750503812 scopus 로고    scopus 로고
    • Oxygen status of lung granulomas in Mycobacterium tuberculosis-infected mice
    • Aly S, et al. Oxygen status of lung granulomas in Mycobacterium tuberculosis-infected mice. J Pathol 2006;210:298-305.
    • (2006) J Pathol , vol.210 , pp. 298-305
    • Aly, S.1
  • 76
    • 35948964746 scopus 로고    scopus 로고
    • Location of persisting mycobacteria in a Guinea pig model of tuberculosis revealed by r207910
    • Lenaerts AJ, et al. Location of persisting mycobacteria in a Guinea pig model of tuberculosis revealed by r207910. Antimicrob Agents Chemother 2007;51:3338-3345.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 3338-3345
    • Lenaerts, A.J.1
  • 77
    • 84856301870 scopus 로고    scopus 로고
    • Mouse model of necrotic tuberculosis granulomas develops hypoxic lesions
    • Harper J, et al. Mouse model of necrotic tuberculosis granulomas develops hypoxic lesions. J Infect Dis 2012;205:595-602.
    • (2012) J Infect Dis , vol.205 , pp. 595-602
    • Harper, J.1
  • 78
    • 0042140672 scopus 로고    scopus 로고
    • Inhibition of respiration by nitric oxide induces a Mycobacterium tuberculosis dormancy program
    • Voskuil MI, et al. Inhibition of respiration by nitric oxide induces a Mycobacterium tuberculosis dormancy program. J Exp Med 2003;198:705-713.
    • (2003) J Exp Med , vol.198 , pp. 705-713
    • Voskuil, M.I.1
  • 79
    • 0029976980 scopus 로고    scopus 로고
    • An in vitro model for sequential study of shiftdown of Mycobacterium tuberculosis through two stages of nonreplicating persistence
    • Wayne LG, Hayes LG. An in vitro model for sequential study of shiftdown of Mycobacterium tuberculosis through two stages of nonreplicating persistence. Infect Immun 1996;64:2062-2069.
    • (1996) Infect Immun , vol.64 , pp. 2062-2069
    • Wayne, L.G.1    Hayes, L.G.2
  • 80
    • 0032170012 scopus 로고    scopus 로고
    • Hypoxia and vascular endothelial growth factor expression in human squamous cell carcinomas using pimonidazole as a hypoxia marker
    • Raleigh JA, et al. Hypoxia and vascular endothelial growth factor expression in human squamous cell carcinomas using pimonidazole as a hypoxia marker. Cancer Res 1998;58:3765-3768.
    • (1998) Cancer Res , vol.58 , pp. 3765-3768
    • Raleigh, J.A.1
  • 81
    • 84904866706 scopus 로고
    • Nekrose und autolyse beitrag zur kenntnis der dystrophischen verkalkung
    • Koller F, Leuthardt F. Nekrose und autolyse beitrag zur kenntnis der dystrophischen verkalkung. Klin Wochenschr 1934;43:1527-1529.
    • (1934) Klin Wochenschr , vol.43 , pp. 1527-1529
    • Koller, F.1    Leuthardt, F.2
  • 82
    • 80055079575 scopus 로고    scopus 로고
    • Fumarate reductase activity maintains an energized membrane in anaerobic Mycobacterium tuberculosis
    • Watanabe S, et al. Fumarate reductase activity maintains an energized membrane in anaerobic Mycobacterium tuberculosis. PLoS Pathog 2011;7:e1002287.
    • (2011) PLoS Pathog , vol.7 , pp. e1002287
    • Watanabe, S.1
  • 83
    • 77956930778 scopus 로고    scopus 로고
    • Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism
    • Kim MJ, et al. Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism. EMBO Mol Med 2010;2:258-274.
    • (2010) EMBO Mol Med , vol.2 , pp. 258-274
    • Kim, M.J.1
  • 84
    • 33645236362 scopus 로고    scopus 로고
    • A novel lipase belonging to the hormone-sensitive lipase family induced under starvation to utilize stored triacylglycerol in Mycobacterium tuberculosis
    • Deb C, et al. A novel lipase belonging to the hormone-sensitive lipase family induced under starvation to utilize stored triacylglycerol in Mycobacterium tuberculosis. J Biol Chem 2006;281:3866-3875.
    • (2006) J Biol Chem , vol.281 , pp. 3866-3875
    • Deb, C.1
  • 85
    • 37249034633 scopus 로고    scopus 로고
    • Gene expression profiles of bronchoalveolar cells in pulmonary TB
    • Raju B, et al. Gene expression profiles of bronchoalveolar cells in pulmonary TB. Tuberculosis 2008;88:39-51.
    • (2008) Tuberculosis , vol.88 , pp. 39-51
    • Raju, B.1
  • 86
    • 41949119272 scopus 로고    scopus 로고
    • Mycobacterial persistence requires the utilization of host cholesterol
    • Pandey AK, Sassetti CM. Mycobacterial persistence requires the utilization of host cholesterol. Proc Natl Acad Sci USA 2008;105:4376-4380.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 4376-4380
    • Pandey, A.K.1    Sassetti, C.M.2
  • 87
    • 79551641984 scopus 로고    scopus 로고
    • Watching intracellular lipolysis in mycobacteria using time lapse fluorescence microscopy
    • Dhouib R, et al. Watching intracellular lipolysis in mycobacteria using time lapse fluorescence microscopy. Biochim Biophys Acta 2011;1811:234-241.
    • (2011) Biochim Biophys Acta , vol.1811 , pp. 234-241
    • Dhouib, R.1
  • 88
    • 79959815079 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis uses host triacylglycerol to accumulate lipid droplets and acquires a dormancy-like phenotype in lipid-loaded macrophages
    • Daniel J, et al. Mycobacterium tuberculosis uses host triacylglycerol to accumulate lipid droplets and acquires a dormancy-like phenotype in lipid-loaded macrophages. PLoS Pathog 2011;7:e1002093.
    • (2011) PLoS Pathog , vol.7 , pp. e1002093
    • Daniel, J.1
  • 89
    • 43249101747 scopus 로고    scopus 로고
    • Cytological and transcript analyses reveal fat and lazy persister-like bacilli in tuberculous sputum
    • Garton NJ, et al. Cytological and transcript analyses reveal fat and lazy persister-like bacilli in tuberculous sputum. PLoS Med 2008;5:e75.
    • (2008) PLoS Med , vol.5 , pp. e75
    • Garton, N.J.1
  • 90
    • 84893020254 scopus 로고    scopus 로고
    • Reversible lipid accumulation and associated division arrest of Mycobacterium avium in lipoprotein-induced foamy macrophages may resemble key events during latency and reactivation of tuberculosis
    • Caire-Brandli I, et al. Reversible lipid accumulation and associated division arrest of Mycobacterium avium in lipoprotein-induced foamy macrophages may resemble key events during latency and reactivation of tuberculosis. Infect Immun 2014;82:476-490.
    • (2014) Infect Immun , vol.82 , pp. 476-490
    • Caire-Brandli, I.1
  • 91
    • 84859972311 scopus 로고    scopus 로고
    • Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death
    • Simeone R, et al. Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death. PLoS Pathog 2012;8:e1002507.
    • (2012) PLoS Pathog , vol.8 , pp. e1002507
    • Simeone, R.1
  • 92
    • 15244340430 scopus 로고    scopus 로고
    • Mechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis
    • Vergne I, et al. Mechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis. Proc Natl Acad Sci USA 2005;102:4033-4038.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 4033-4038
    • Vergne, I.1
  • 93
    • 33744531073 scopus 로고    scopus 로고
    • Profiling of Mycobacterium tuberculosis gene expression during human macrophage infection: upregulation of the alternative sigma factor G, a group of transcriptional regulators, and proteins with unknown function
    • Cappelli G, et al. Profiling of Mycobacterium tuberculosis gene expression during human macrophage infection: upregulation of the alternative sigma factor G, a group of transcriptional regulators, and proteins with unknown function. Res Microbiol 2006;157:445-455.
    • (2006) Res Microbiol , vol.157 , pp. 445-455
    • Cappelli, G.1
  • 94
    • 0043142536 scopus 로고    scopus 로고
    • Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: insights into the phagosomal environment
    • Schnappinger D, et al. Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: insights into the phagosomal environment. J Exp Med 2003;198:693-704.
    • (2003) J Exp Med , vol.198 , pp. 693-704
    • Schnappinger, D.1
  • 95
    • 38849177346 scopus 로고    scopus 로고
    • Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages
    • Tailleux L, et al. Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages. PLoS ONE 2008;3:e1403.
    • (2008) PLoS ONE , vol.3 , pp. e1403
    • Tailleux, L.1
  • 96
    • 1842585499 scopus 로고    scopus 로고
    • The temporal expression profile of Mycobacterium tuberculosis infection in mice
    • Talaat AM, et al. The temporal expression profile of Mycobacterium tuberculosis infection in mice. Proc Natl Acad Sci USA 2004;101:4602-4607.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 4602-4607
    • Talaat, A.M.1
  • 97
    • 0034679958 scopus 로고    scopus 로고
    • Lipid lunch for persistent pathogen
    • Bishai W. Lipid lunch for persistent pathogen. Nature 2000;406:683-685.
    • (2000) Nature , vol.406 , pp. 683-685
    • Bishai, W.1
  • 98
    • 0342794213 scopus 로고    scopus 로고
    • Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase
    • McKinney JD, et al. Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase. Nature 2000;406:735-738.
    • (2000) Nature , vol.406 , pp. 735-738
    • McKinney, J.D.1
  • 99
    • 20944450448 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence
    • Munoz-Elias EJ, McKinney JD. Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence. Nat Med 2005;11:638-644.
    • (2005) Nat Med , vol.11 , pp. 638-644
    • Munoz-Elias, E.J.1    McKinney, J.D.2
  • 100
    • 77953105101 scopus 로고    scopus 로고
    • Gluconeogenic carbon flow of tricarboxylic acid cycle intermediates is critical for Mycobacterium tuberculosis to establish and maintain infection
    • Marrero J, et al. Gluconeogenic carbon flow of tricarboxylic acid cycle intermediates is critical for Mycobacterium tuberculosis to establish and maintain infection. Proc Natl Acad Sci USA 2010;107:9819-9824.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 9819-9824
    • Marrero, J.1
  • 101
    • 0036139212 scopus 로고    scopus 로고
    • Dependence of Mycobacterium bovis BCG on anaerobic nitrate reductase for persistence is tissue specific
    • Fritz C, et al. Dependence of Mycobacterium bovis BCG on anaerobic nitrate reductase for persistence is tissue specific. Infect Immun 2002;70:286-291.
    • (2002) Infect Immun , vol.70 , pp. 286-291
    • Fritz, C.1
  • 102
    • 0032725878 scopus 로고    scopus 로고
    • Molecular genetic characterisation of whiB3, a mycobacterial homologue of a Streptomyces sporulation factor
    • Hutter B, Dick T. Molecular genetic characterisation of whiB3, a mycobacterial homologue of a Streptomyces sporulation factor. Res Microbiol 1999;150:295-301.
    • (1999) Res Microbiol , vol.150 , pp. 295-301
    • Hutter, B.1    Dick, T.2
  • 103
    • 0034012134 scopus 로고    scopus 로고
    • Anaerobic nitrate reductase (narGHJI) activity of Mycobacterium bovis BCG in vitro and its contribution to virulence in immunodeficient mice
    • Weber I, et al. Anaerobic nitrate reductase (narGHJI) activity of Mycobacterium bovis BCG in vitro and its contribution to virulence in immunodeficient mice. Mol Microbiol 2000;35:1017-1025.
    • (2000) Mol Microbiol , vol.35 , pp. 1017-1025
    • Weber, I.1
  • 104
    • 10744233688 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis growth at the cavity surface: a microenvironment with failed immunity
    • Kaplan G, et al. Mycobacterium tuberculosis growth at the cavity surface: a microenvironment with failed immunity. Infect Immun 2003;71:7099-7108.
    • (2003) Infect Immun , vol.71 , pp. 7099-7108
    • Kaplan, G.1
  • 105
    • 0001687214 scopus 로고
    • Mechanism of softening of tubercles. III. Hydrolysis of protein and nucleic acid during anaerobic autolysis of normal and tuberculous lung tissue in vitro
    • Weiss C, Tabachnick J, Cohen HP. Mechanism of softening of tubercles. III. Hydrolysis of protein and nucleic acid during anaerobic autolysis of normal and tuberculous lung tissue in vitro. AMA Arch Pathol 1954;57:179-193.
    • (1954) AMA Arch Pathol , vol.57 , pp. 179-193
    • Weiss, C.1    Tabachnick, J.2    Cohen, H.P.3
  • 106
    • 0015954778 scopus 로고
    • The role of cathepsin D in the pathogenesis of tuberculosis. A histochemical study employing unlabeled antibodies and the peroxidase-antiperoxidase complex
    • Rojas-Espinosa O, et al. The role of cathepsin D in the pathogenesis of tuberculosis. A histochemical study employing unlabeled antibodies and the peroxidase-antiperoxidase complex. Am J Pathol 1974;74:1-17.
    • (1974) Am J Pathol , vol.74 , pp. 1-17
    • Rojas-Espinosa, O.1
  • 107
    • 0016074025 scopus 로고
    • Prevention of tuberculous cavity formation by desensitization with tuberculin-active peptide
    • Yamamura Y, Ogawa Y, Maeda H. Prevention of tuberculous cavity formation by desensitization with tuberculin-active peptide. Am Rev Respir Dis 1974;109:594-601.
    • (1974) Am Rev Respir Dis , vol.109 , pp. 594-601
    • Yamamura, Y.1    Ogawa, Y.2    Maeda, H.3
  • 108
    • 84922572760 scopus 로고    scopus 로고
    • In vivo prediction of tuberculosis cavity formation in rabbits
    • Luna B, et al. In vivo prediction of tuberculosis cavity formation in rabbits. J Infect Dis 2014;211:481-485.
    • (2014) J Infect Dis , vol.211 , pp. 481-485
    • Luna, B.1
  • 109
    • 0035949685 scopus 로고    scopus 로고
    • Divergent effect of bacillus Calmette-Guerin (BCG) vaccination on Mycobacterium tuberculosis infection in highly related macaque species: implications for primate models in tuberculosis vaccine research
    • Langermans JA, et al. Divergent effect of bacillus Calmette-Guerin (BCG) vaccination on Mycobacterium tuberculosis infection in highly related macaque species: implications for primate models in tuberculosis vaccine research. Proc Natl Acad Sci USA 2001;98:11497-11502.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 11497-11502
    • Langermans, J.A.1
  • 110
    • 31144446585 scopus 로고    scopus 로고
    • New insights into the function of granulomas in human tuberculosis
    • Ulrichs T, Kaufmann SH. New insights into the function of granulomas in human tuberculosis. J Pathol 2006;208:261-269.
    • (2006) J Pathol , vol.208 , pp. 261-269
    • Ulrichs, T.1    Kaufmann, S.H.2
  • 111
    • 85179186726 scopus 로고    scopus 로고
    • Pathology of tuberculosis in the human lung
    • Leong FJ, Dartois V, Dick T eds. CRC Press
    • Leong FJ, et al. Pathology of tuberculosis in the human lung. In: Leong FJ, Dartois V, Dick T eds. A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis. CRC Press, 2011:53-81.
    • (2011) A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis , pp. 53-81
    • Leong, F.J.1
  • 112
    • 34347333552 scopus 로고    scopus 로고
    • Interferon-gamma-dependent mechanisms of mycobacteria-induced pulmonary immunopathology: the role of angiostasis and CXCR3-targeted chemokines for granuloma necrosis
    • Aly S, et al. Interferon-gamma-dependent mechanisms of mycobacteria-induced pulmonary immunopathology: the role of angiostasis and CXCR3-targeted chemokines for granuloma necrosis. J Pathol 2007;212:295-305.
    • (2007) J Pathol , vol.212 , pp. 295-305
    • Aly, S.1
  • 113
    • 49749129255 scopus 로고    scopus 로고
    • Contrasting effects of human THP-1 cell differentiation on levofloxacin and moxifloxacin intracellular accumulation and activity against Staphylococcus aureus and Listeria monocytogenes
    • Van de Velde S, et al. Contrasting effects of human THP-1 cell differentiation on levofloxacin and moxifloxacin intracellular accumulation and activity against Staphylococcus aureus and Listeria monocytogenes. J Antimicrob Chemother 2008;62:518-521.
    • (2008) J Antimicrob Chemother , vol.62 , pp. 518-521
    • Van de Velde, S.1
  • 114
    • 84889079235 scopus 로고    scopus 로고
    • Activity and interactions of levofloxacin, linezolid, ethambutol and amikacin in three-drug combinations against Mycobacterium tuberculosis isolates in a human macrophage model
    • Rey-Jurado E, et al. Activity and interactions of levofloxacin, linezolid, ethambutol and amikacin in three-drug combinations against Mycobacterium tuberculosis isolates in a human macrophage model. Int J Antimicrob Agents 2013;42:524-530.
    • (2013) Int J Antimicrob Agents , vol.42 , pp. 524-530
    • Rey-Jurado, E.1
  • 115
    • 84874046848 scopus 로고    scopus 로고
    • Multiscale distribution and bioaccumulation analysis of clofazimine reveals a massive immune system-mediated xenobiotic sequestration response
    • Baik J, et al. Multiscale distribution and bioaccumulation analysis of clofazimine reveals a massive immune system-mediated xenobiotic sequestration response. Antimicrob Agents Chemother 2013;57:1218-1230.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 1218-1230
    • Baik, J.1
  • 116
    • 79954595692 scopus 로고    scopus 로고
    • High-sensitivity MALDI-MRM-MS imaging of moxifloxacin distribution in tuberculosis-infected rabbit lungs and granulomatous lesions
    • Prideaux B, et al. High-sensitivity MALDI-MRM-MS imaging of moxifloxacin distribution in tuberculosis-infected rabbit lungs and granulomatous lesions. Anal Chem 2011;83:2112-2118.
    • (2011) Anal Chem , vol.83 , pp. 2112-2118
    • Prideaux, B.1
  • 117
    • 84865200761 scopus 로고    scopus 로고
    • Mass spectrometry imaging for drug distribution studies
    • Prideaux B, Stoeckli M. Mass spectrometry imaging for drug distribution studies. J Prot 2012;75:4999-5013.
    • (2012) J Prot , vol.75 , pp. 4999-5013
    • Prideaux, B.1    Stoeckli, M.2
  • 118
    • 84905992315 scopus 로고    scopus 로고
    • Simvastatin increases the in vivo activity of the first-line tuberculosis regimen
    • Skerry C, et al. Simvastatin increases the in vivo activity of the first-line tuberculosis regimen. J Antimicrob Chemother 2014;69:2453-2457.
    • (2014) J Antimicrob Chemother , vol.69 , pp. 2453-2457
    • Skerry, C.1
  • 119
    • 80052456289 scopus 로고    scopus 로고
    • Phosphodiesterase-4 inhibition combined with isoniazid treatment of rabbits with pulmonary tuberculosis reduces macrophage activation and lung pathology
    • Subbian S, et al. Phosphodiesterase-4 inhibition combined with isoniazid treatment of rabbits with pulmonary tuberculosis reduces macrophage activation and lung pathology. Am J Pathol 2011;179:289-301.
    • (2011) Am J Pathol , vol.179 , pp. 289-301
    • Subbian, S.1
  • 120
    • 84903597076 scopus 로고    scopus 로고
    • Cutting edge: vitamin D regulates lipid metabolism in Mycobacterium tuberculosis infection
    • Salamon H, et al. Cutting edge: vitamin D regulates lipid metabolism in Mycobacterium tuberculosis infection. J Immunol 2014;193:30-34.
    • (2014) J Immunol , vol.193 , pp. 30-34
    • Salamon, H.1
  • 121
    • 77955342203 scopus 로고    scopus 로고
    • Darapladib: an emerging therapy for atherosclerosis
    • Corson MA. Darapladib: an emerging therapy for atherosclerosis. Ther Adv Cardiovasc Dis 2010;4:241-248.
    • (2010) Ther Adv Cardiovasc Dis , vol.4 , pp. 241-248
    • Corson, M.A.1
  • 122
    • 54049152760 scopus 로고    scopus 로고
    • Effects of the direct lipoprotein-associated phospholipase A(2) inhibitor darapladib on human coronary atherosclerotic plaque
    • Serruys PW, et al. Effects of the direct lipoprotein-associated phospholipase A(2) inhibitor darapladib on human coronary atherosclerotic plaque. Circulation 2008;118:1172-1182.
    • (2008) Circulation , vol.118 , pp. 1172-1182
    • Serruys, P.W.1
  • 123
    • 84904543855 scopus 로고    scopus 로고
    • Anti-inflammatory therapies for cardiovascular disease
    • Ridker PM, Luscher TF. Anti-inflammatory therapies for cardiovascular disease. Eur Heart J 2014;35:1782-1791.
    • (2014) Eur Heart J , vol.35 , pp. 1782-1791
    • Ridker, P.M.1    Luscher, T.F.2
  • 124
    • 0032821532 scopus 로고    scopus 로고
    • Studies on the treatment of tuberculosis undertaken by the British Medical Research Council tuberculosis units, 1946-1986, with relevant subsequent publications
    • Fox W, Ellard GA, Mitchison DA. Studies on the treatment of tuberculosis undertaken by the British Medical Research Council tuberculosis units, 1946-1986, with relevant subsequent publications. Int J Tuberc Lung Dis 1999;3(10 Suppl 2):S231-S279.
    • (1999) Int J Tuberc Lung Dis , vol.3 , Issue.10 , pp. S231-S279
    • Fox, W.1    Ellard, G.A.2    Mitchison, D.A.3
  • 125
    • 0022335191 scopus 로고
    • The action of antituberculosis drugs in short-course chemotherapy
    • Mitchison DA. The action of antituberculosis drugs in short-course chemotherapy. Tubercle 1985;66:219-225.
    • (1985) Tubercle , vol.66 , pp. 219-225
    • Mitchison, D.A.1
  • 126
    • 79953218013 scopus 로고    scopus 로고
    • Reduction of clofazimine by mycobacterial type 2 NADH:quinone oxidoreductase: a pathway for the generation of bactericidal levels of reactive oxygen species
    • Yano T, et al. Reduction of clofazimine by mycobacterial type 2 NADH:quinone oxidoreductase: a pathway for the generation of bactericidal levels of reactive oxygen species. J Biol Chem 2011;286:10276-10287.
    • (2011) J Biol Chem , vol.286 , pp. 10276-10287
    • Yano, T.1
  • 127
    • 0037439401 scopus 로고    scopus 로고
    • Whole blood bactericidal activity during treatment of pulmonary tuberculosis
    • Wallis RS, et al. Whole blood bactericidal activity during treatment of pulmonary tuberculosis. J Infect Dis 2003;187:270-278.
    • (2003) J Infect Dis , vol.187 , pp. 270-278
    • Wallis, R.S.1
  • 128
    • 84901289434 scopus 로고    scopus 로고
    • Population pharmacokinetic/pharmacodynamic analysis of the bactericidal activities of sutezolid (PNU-100480) and its major metabolite against intracellular mycobacterium tuberculosis in ex vivo whole-blood cultures of patients with pulmonary tuberculosis
    • Zhu T, et al. Population pharmacokinetic/pharmacodynamic analysis of the bactericidal activities of sutezolid (PNU-100480) and its major metabolite against intracellular mycobacterium tuberculosis in ex vivo whole-blood cultures of patients with pulmonary tuberculosis. Antimicrob Agents Chemother 2014;58:3306-3311.
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 3306-3311
    • Zhu, T.1
  • 129
    • 0031656471 scopus 로고    scopus 로고
    • Metronidazole has no antibacterial effect in Cornell model murine tuberculosis
    • Dhillon J, et al. Metronidazole has no antibacterial effect in Cornell model murine tuberculosis. Int J Tuberc Lung Dis 1998;2:736-742.
    • (1998) Int J Tuberc Lung Dis , vol.2 , pp. 736-742
    • Dhillon, J.1
  • 130
    • 84865540183 scopus 로고    scopus 로고
    • Metronidazole prevents reactivation of latent Mycobacterium tuberculosis infection in macaques
    • Lin PL, et al. Metronidazole prevents reactivation of latent Mycobacterium tuberculosis infection in macaques. Proc Natl Acad Sci USA 2012;109:14188-14193.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 14188-14193
    • Lin, P.L.1
  • 131
    • 55849117720 scopus 로고    scopus 로고
    • Metronidazole lacks antibacterial activity in guinea pigs infected with Mycobacterium tuberculosis
    • Hoff DR, et al. Metronidazole lacks antibacterial activity in guinea pigs infected with Mycobacterium tuberculosis. Antimicrob Agents Chemother 2008;52:4137-4140.
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 4137-4140
    • Hoff, D.R.1
  • 132
    • 84880271014 scopus 로고    scopus 로고
    • Efficacy and safety of metronidazole for pulmonary multidrug-resistant tuberculosis
    • Carroll MW, et al. Efficacy and safety of metronidazole for pulmonary multidrug-resistant tuberculosis. Antimicrob Agents Chemother 2013;57:3903-3909.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 3903-3909
    • Carroll, M.W.1
  • 133
    • 84879935517 scopus 로고    scopus 로고
    • Looking within the zebrafish to understand the tuberculous granuloma
    • Ramakrishnan L. Looking within the zebrafish to understand the tuberculous granuloma. Adv Exp Med Biol 2013;783:251-266.
    • (2013) Adv Exp Med Biol , vol.783 , pp. 251-266
    • Ramakrishnan, L.1
  • 134
    • 33750439462 scopus 로고    scopus 로고
    • Mycobacterium marinum infection of adult zebrafish causes caseating granulomatous tuberculosis and is moderated by adaptive immunity
    • Swaim LE, et al. Mycobacterium marinum infection of adult zebrafish causes caseating granulomatous tuberculosis and is moderated by adaptive immunity. Infect Immun 2006;74:6108-6117.
    • (2006) Infect Immun , vol.74 , pp. 6108-6117
    • Swaim, L.E.1
  • 135
    • 50349094162 scopus 로고    scopus 로고
    • Experimental tuberculosis: the role of comparative pathology in the discovery of improved tuberculosis treatment strategies
    • Basaraba RJ. Experimental tuberculosis: the role of comparative pathology in the discovery of improved tuberculosis treatment strategies. Tuberculosis 2008;88(Suppl 1):S35-S47.
    • (2008) Tuberculosis , vol.88 , pp. S35-S47
    • Basaraba, R.J.1
  • 136
    • 84864383796 scopus 로고    scopus 로고
    • Dose-ranging comparison of rifampin and rifapentine in two pathologically distinct murine models of tuberculosis
    • Rosenthal IM, et al. Dose-ranging comparison of rifampin and rifapentine in two pathologically distinct murine models of tuberculosis. Antimicrob Agents Chemother 2012;56:4331-4340.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 4331-4340
    • Rosenthal, I.M.1
  • 137
    • 82755167837 scopus 로고    scopus 로고
    • BCG induces protection against Mycobacterium tuberculosis infection in the Wistar rat model
    • Singhal A, et al. BCG induces protection against Mycobacterium tuberculosis infection in the Wistar rat model. PLoS ONE 2011;6:e28082.
    • (2011) PLoS ONE , vol.6 , pp. e28082
    • Singhal, A.1
  • 138
    • 45649085197 scopus 로고    scopus 로고
    • Disseminated disease severity as a measure of virulence of Mycobacterium tuberculosis in the guinea pig model
    • Palanisamy GS, et al. Disseminated disease severity as a measure of virulence of Mycobacterium tuberculosis in the guinea pig model. Tuberculosis 2008;88:295-306.
    • (2008) Tuberculosis , vol.88 , pp. 295-306
    • Palanisamy, G.S.1
  • 139
    • 84882261503 scopus 로고    scopus 로고
    • Experimental aerosol Mycobacterium bovis model of infection in goats
    • Gonzalez-Juarrero M, et al. Experimental aerosol Mycobacterium bovis model of infection in goats. Tuberculosis 2013;93:558-564.
    • (2013) Tuberculosis , vol.93 , pp. 558-564
    • Gonzalez-Juarrero, M.1
  • 140
    • 79960280596 scopus 로고    scopus 로고
    • Microscopical and immunological features of tuberculoid granulomata and cavitary pulmonary tuberculosis in naturally infected goats
    • Sanchez J, et al. Microscopical and immunological features of tuberculoid granulomata and cavitary pulmonary tuberculosis in naturally infected goats. J Comp Pathol 2011;145:107-117.
    • (2011) J Comp Pathol , vol.145 , pp. 107-117
    • Sanchez, J.1
  • 141
    • 77956299896 scopus 로고    scopus 로고
    • Granuloma encapsulation is a key factor for containing tuberculosis infection in minipigs
    • Gil O, et al. Granuloma encapsulation is a key factor for containing tuberculosis infection in minipigs. PLoS ONE 2010;5:e10030.
    • (2010) PLoS ONE , vol.5 , pp. e10030
    • Gil, O.1
  • 142
    • 84861483812 scopus 로고    scopus 로고
    • The non-human primate model of tuberculosis
    • Kaushal D, et al. The non-human primate model of tuberculosis. J Med Primatol 2012;41:191-201.
    • (2012) J Med Primatol , vol.41 , pp. 191-201
    • Kaushal, D.1
  • 143
    • 33745622432 scopus 로고    scopus 로고
    • Early events in Mycobacterium tuberculosis infection in cynomolgus macaques
    • Lin PL, et al. Early events in Mycobacterium tuberculosis infection in cynomolgus macaques. Infect Immun 2006;74:3790-3803.
    • (2006) Infect Immun , vol.74 , pp. 3790-3803
    • Lin, P.L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.