Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death

PLoS Pathogens

Volumn 8, Issue 2, 2012, Pages

  Simeone, Roxane ^a   Bobard, Alexandre ^a   Lippmann, Juliane ^a   Bitter, Wilbert ^b   Majlessi, Laleh ^a,c   Brosch, Roland ^a   Enninga, Jost ^a  

^a INSTITUT PASTEUR   (France)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

^c INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; EARLY SECRETORY ANTIGENIC TARGET 6; PROTEIN ESX 1; UNCLASSIFIED DRUG; ESX1 PROTEIN, HUMAN; HOMEODOMAIN PROTEIN;

ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM MUTANT; CELL DEATH; CYTOLYSIS; CYTOSOL; CYTOTOXICITY; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE DELETION; HOST CELL; HOST PATHOGEN INTERACTION; HOST RESISTANCE; HUMAN; HUMAN CELL; INNATE IMMUNITY; MACROPHAGE; MYCOBACTERIUM MARINUM; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHAGOLYSOSOME; PHAGOLYSOSOME RUPTURE; WILD TYPE; CELL LINE; IMMUNE EVASION; IMMUNOLOGY; METABOLISM; METHODOLOGY; MICROBIOLOGY; MYCOBACTERIOSIS; PATHOGENICITY; PATHOLOGY; PHAGOSOME; SALMONELLA TYPHIMURIUM; SHIGELLA FLEXNERI;

MYCOBACTERIUM MARINUM; MYCOBACTERIUM TUBERCULOSIS;

CELL DEATH; CELL LINE; FLUORESCENCE RESONANCE ENERGY TRANSFER; HOMEODOMAIN PROTEINS; HUMANS; IMMUNE EVASION; MACROPHAGES; MYCOBACTERIUM INFECTIONS; MYCOBACTERIUM MARINUM; MYCOBACTERIUM TUBERCULOSIS; PHAGOSOMES; SALMONELLA TYPHIMURIUM; SHIGELLA FLEXNERI;

EID: 84859972311     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002507     Document Type: Article

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