Mycobacterium tuberculosis dysregulates MMP/TIMP balance to drive rapid cavitation and unrestrained bacterial proliferation

Journal of Pathology

Volumn 235, Issue 3, 2015, Pages 431-444

  Kübler, André ^a,b   Luna, Brian ^b   Larsson, Christer ^c   Ammerman, Nicole C ^d   Andrade, Bruno B ^e   Orandle, Marlene ^e   Bock, Kevin W ^e   Xu, Ziyue ^f   Bagci, Ulas ^f   Molura, Daniel J ^f   Marshall, John ^b   Burns, Jay ^g   Winglee, Kathryn ^b   Ahidjo, Bintou Ahmadou ^b,j   Cheung, Laurene S ^b   Klunk, Mariah ^h   Jain, Sanjay K ^b,h   Kumar, Nathella Pavan ^f,k   Babu, Subash ^e,f   Sher, Alan ^e   Friedland, Jon S ^a   Elkington, Paul T G ^a,i   Bishai, William R ^b,j,l   more..

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UMEÅ UNIVERSITY   (Sweden)

^d AFRICA HEALTH RESEARCH INSTITUTE   (South Africa)

^e NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^f NATIONAL INSTITUTES OF HEALTH   (United States)

^g Johns Hopkins University   (United States)

^h Center for Infectious Disease and Inflammation Imaging Research (CI3R)   (United States)

ⁱ UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^j HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^k NATIONAL INSTITUTE FOR RESEARCH IN TUBERCULOSIS   (India)

^l JOHNS HOPKINS UNIVERSITY   (United States)

more..

Author keywords

Cavity; Computed tomography; Matrix metalloproteinase; Tuberculosis

Indexed keywords

COLLAGENASE 3; GELATINASE A; INTERSTITIAL COLLAGENASE; MATRILYSIN; MATRIX METALLOPROTEINASE; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 3; METALLOPROTEINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL LOAD; BACTERIAL VIRULENCE; COLONY FORMING UNIT; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; EXPERIMENTAL RABBIT; FEMALE; GRANULOMATOUS INFLAMMATION; IMAGE ANALYSIS; LUNG CAVITATION; LUNG PARENCHYMA; LUNG TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; DISEASE MODEL; GROWTH, DEVELOPMENT AND AGING; HOMEOSTASIS; IMAGE PROCESSING; LUNG; METABOLISM; MICROBIOLOGY; PATHOLOGY; PHYSIOLOGY; RABBIT; RADIOGRAPHY; SKIN TEST; TUBERCULOSIS;

ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; HOMEOSTASIS; IMAGE PROCESSING, COMPUTER-ASSISTED; LUNG; MATRIX METALLOPROTEINASE 1; METALLOPROTEASES; MYCOBACTERIUM TUBERCULOSIS; RABBITS; SKIN TESTS; TISSUE INHIBITOR OF METALLOPROTEINASE-3; TISSUE INHIBITOR OF METALLOPROTEINASES; TOMOGRAPHY, X-RAY COMPUTED; TUBERCULOSIS;

EID: 84920736281     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.4432     Document Type: Article

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