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Volumn 12, Issue 5, 2012, Pages 352-366

Revisiting the role of the granuloma in tuberculosis

Author keywords

[No Author keywords available]

Indexed keywords

BCG VACCINE; EARLY SECRETORY ANTIGENIC TARGET 6; GAMMA INTERFERON; GELATINASE B; INTERLEUKIN 12; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN SERINE THREONINE KINASE; STAT4 PROTEIN; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR; VIRULENCE FACTOR;

EID: 84860247190     PISSN: 14741733     EISSN: 14741741     Source Type: Journal    
DOI: 10.1038/nri3211     Document Type: Review
Times cited : (644)

References (169)
  • 3
    • 0002639887 scopus 로고
    • (eds Pinner, D. M. & Pinner, M.) (National Tuberculosis Association
    • Koch, R. The Aetiology of Tuberculosis (eds Pinner, D. M. & Pinner, M.) (National Tuberculosis Association, 1882).
    • (1882) The Aetiology of Tuberculosis
    • Koch, R.1
  • 4
    • 0020077941 scopus 로고
    • Richard Morton (1637-98) and his phthisiologia
    • Keers, R. Richard Morton (1637-98) and his Phthisiologia. Thorax 37, 26-31 (1982). (Pubitemid 12192064)
    • (1982) Thorax , vol.37 , Issue.1 , pp. 26-31
    • Keers, R.Y.1
  • 5
    • 0016051838 scopus 로고
    • Development of knowledge of unity of tuberculosis and of the portals of entry of tubercle bacilli
    • Myers, J. Development of knowledge of unity of tuberculosis and of the portals of entry of tubercle bacilli. J. Hist. Med. Allied Sci. 29, 213-228 (1974).
    • (1974) J. Hist. Med. Allied Sci. , vol.29 , pp. 213-228
    • Myers, J.1
  • 6
    • 0020048721 scopus 로고
    • Robert Koch: Centenary of the discovery of the tubercle bacillus, 1882
    • Sakula, A. Robert Koch: centenary of the discovery of the tubercle bacillus, 1882. Thorax 37, 246-251 (1982). (Pubitemid 12108474)
    • (1982) Thorax , vol.37 , Issue.4 , pp. 246-251
    • Sakula, A.1
  • 7
    • 0017075792 scopus 로고
    • The granulomatous inflammatory response. A review
    • Adams, D. O. The granulomatous inflammatory response. A review. Am. J. Pathol. 84, 164-192 (1976).
    • (1976) Am. J. Pathol. , vol.84 , pp. 164-192
    • Adams, D.O.1
  • 8
    • 0014634514 scopus 로고
    • The granulomatous inflammatory exudate
    • Spector, W. G. The granulomatous inflammatory exudate. Int. Rev. Exp. Pathol. 8, 1-55 (1969).
    • (1969) Int. Rev. Exp. Pathol. , vol.8 , pp. 1-55
    • Spector, W.G.1
  • 9
    • 0020526146 scopus 로고
    • Granulomatous inflammation - A review
    • Williams, G. T. & Williams, W. J. Granulomatous inflammation-a review. J. Clin. Pathol. 36, 723-733 (1983).
    • (1983) J. Clin. Pathol. , vol.36 , pp. 723-733
    • Williams, G.T.1    Williams, W.J.2
  • 10
    • 0016253236 scopus 로고
    • The structure of mononuclear phagocytes differentiating in vivo. I. Sequential fine and histologic studies of the effect of Bacillus Calmette-Guerin (BCG)
    • Adams, D. O. The structure of mononuclear phagocytes differentiating in vivo. I. Sequential fine and histologic studies of the effect of Bacillus Calmette-Guerin (BCG). Am. J. Pathol. 76, 17-48 (1974).
    • (1974) Am. J. Pathol. , vol.76 , pp. 17-48
    • Adams, D.O.1
  • 11
    • 0014376491 scopus 로고
    • The structure and function of monocytes and macrophages
    • Cohn, Z. A. The structure and function of monocytes and macrophages. Adv. Immunol. 9, 163-214 (1968).
    • (1968) Adv. Immunol. , vol.9 , pp. 163-214
    • Cohn, Z.A.1
  • 12
    • 0014291846 scopus 로고
    • Cellular hypersensitivity and cellular immunity in the pathogensis of tuberculosis: Specificity, systemic and local nature, and associated macrophage enzymes
    • Dannenberg, A. M. Jr. Cellular hypersensitivity and cellular immunity in the pathogensis of tuberculosis: specificity, systemic and local nature, and associated macrophage enzymes. Bacteriol. Rev. 32, 85-102 (1968).
    • (1968) Bacteriol. Rev. , vol.32 , pp. 85-102
    • Dannenberg Jr., A.M.1
  • 13
    • 0035179747 scopus 로고    scopus 로고
    • Dynamic nature of host-pathogen interactions in Mycobacterium marinum granulomas
    • DOI 10.1128/IAI.69.12.7820-7831.2001
    • Bouley, D. M., Ghori, N., Mercer, K. L., Falkow, S. & Ramakrishnan, L. Dynamic nature of host-pathogen interactions in Mycobacterium marinum granulomas. Infect. Immun. 69, 7820-7831 (2001). (Pubitemid 33086613)
    • (2001) Infection and Immunity , vol.69 , Issue.12 , pp. 7820-7831
    • Bouley, D.M.1    Ghori, N.2    Mercer, K.L.3    Falkow, S.4    Ramakrishnan, L.5
  • 14
    • 37049025380 scopus 로고    scopus 로고
    • The molecular basis of macrophage fusion
    • DOI 10.1016/j.imbio.2007.09.012, PII S0171298507001180, Macrophage and Dendritic Cells
    • Helming, L. & Gordon, S. The molecular basis of macrophage fusion. Immunobiology 212, 785-793 (2007). (Pubitemid 350246267)
    • (2008) Immunobiology , vol.212 , Issue.9-10 , pp. 785-793
    • Helming, L.1    Gordon, S.2
  • 15
    • 69049108875 scopus 로고    scopus 로고
    • Foamy macrophages and the progression of the human tuberculosis granuloma
    • Russell, D. G., Cardona, P. J., Kim, M. J., Allain, S. & Altare, F. Foamy macrophages and the progression of the human tuberculosis granuloma. Nature Immunol. 10, 943-948 (2009).
    • (2009) Nature Immunol. , vol.10 , pp. 943-948
    • Russell, D.G.1    Cardona, P.J.2    Kim, M.J.3    Allain, S.4    Altare, F.5
  • 17
    • 52949118482 scopus 로고    scopus 로고
    • The multifaceted contributions of leukocyte subsets to atherosclerosis: Lessons from mouse models
    • Weber, C., Zernecke, A. & Libby, P. The multifaceted contributions of leukocyte subsets to atherosclerosis: lessons from mouse models. Nature Rev. Immunol. 8, 802-815 (2008).
    • (2008) Nature Rev. Immunol. , vol.8 , pp. 802-815
    • Weber, C.1    Zernecke, A.2    Libby, P.3
  • 18
    • 57149096869 scopus 로고    scopus 로고
    • Foamy macrophages from tuberculous patients' granulomas constitute a nutrient-rich reservoir for M. tuberculosis persistence
    • Peyron, P. et al. Foamy macrophages from tuberculous patients' granulomas constitute a nutrient-rich reservoir for M. tuberculosis persistence. PLoS Pathog. 4, e1000204 (2008).
    • (2008) PLoS Pathog. , vol.4
    • Peyron, P.1
  • 20
    • 80755128440 scopus 로고    scopus 로고
    • Pathology of post primary tuberculosis of the lung: An illustrated critical review
    • Hunter, R. L. Pathology of post primary tuberculosis of the lung: an illustrated critical review. Tuberculosis 91, 497-509 (2011).
    • (2011) Tuberculosis , vol.91 , pp. 497-509
    • Hunter, R.L.1
  • 23
    • 75649141266 scopus 로고    scopus 로고
    • Tuberculous granuloma induction via interaction of a bacterial secreted protein with host epithelium
    • Volkman, H. E. et al. Tuberculous granuloma induction via interaction of a bacterial secreted protein with host epithelium. Science 327, 466-469 (2010).
    • (2010) Science , vol.327 , pp. 466-469
    • Volkman, H.E.1
  • 24
    • 0242523806 scopus 로고    scopus 로고
    • The secret lives of the pathogenic mycobacteria
    • DOI 10.1146/annurev.micro.57.030502.091033
    • Cosma, C. L., Sherman, D. R. & Ramakrishnan, L. The secret lives of the pathogenic mycobacteria. Annu. Rev. Microbiol. 57, 641-676 (2003). (Pubitemid 37392957)
    • (2003) Annual Review of Microbiology , vol.57 , pp. 641-676
    • Cosma, C.L.1    Sherman, D.R.2    Ramakrishnan, L.3
  • 25
    • 0000305402 scopus 로고
    • The residual infectivity of the primary complex of tuberculosis
    • Feldman, W. H. & Baggenstoss, A. H. The residual infectivity of the primary complex of tuberculosis. Am. J. Pathol. 14, 473-490 (1938).
    • (1938) Am. J. Pathol. , vol.14 , pp. 473-490
    • Feldman, W.H.1    Baggenstoss, A.H.2
  • 26
    • 0001776002 scopus 로고
    • Tubercle bacilli in latent tuberculous lesions and in lung tissue without tuberculous lesions
    • Opie, E. L. & Aronson, J. D. Tubercle bacilli in latent tuberculous lesions and in lung tissue without tuberculous lesions. Arch. Pathol. Lab. Med. 4, 1-21 (1927).
    • (1927) Arch. Pathol. Lab. Med. , vol.4 , pp. 1-21
    • Opie, E.L.1    Aronson, J.D.2
  • 27
    • 79959927732 scopus 로고    scopus 로고
    • Tuberculosis
    • Lawn, S. D. & Zumla, A. I. Tuberculosis. Lancet 378, 57-72 (2011).
    • (2011) Lancet , vol.378 , pp. 57-72
    • Lawn, S.D.1    Zumla, A.I.2
  • 28
    • 66649092620 scopus 로고    scopus 로고
    • The granuloma in tuberculosis-friend or foe?
    • Rubin, E. J. The granuloma in tuberculosis-friend or foe? N. Engl. J. Med. 360, 2471-2473 (2009).
    • (2009) N. Engl. J. Med. , vol.360 , pp. 2471-2473
    • Rubin, E.J.1
  • 29
    • 58149089157 scopus 로고    scopus 로고
    • Who benefits from granulomas, mycobacteria or host?
    • Bold, T. D. & Ernst, J. D. Who benefits from granulomas, mycobacteria or host? Cell 136, 17-19 (2009).
    • (2009) Cell , vol.136 , pp. 17-19
    • Bold, T.D.1    Ernst, J.D.2
  • 30
    • 31144446585 scopus 로고    scopus 로고
    • New insights into the function of granulomas in human tuberculosis
    • DOI 10.1002/path.1906
    • Ulrichs, T. & Kaufmann, S. H. New insights into the function of granulomas in human tuberculosis. J. Pathol. 208, 261-269 (2006). (Pubitemid 43126118)
    • (2006) Journal of Pathology , vol.208 , Issue.2 , pp. 261-269
    • Ulrichs, T.1    Kaufmann, S.H.E.2
  • 35
    • 34548591486 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis and the environment within the phagosome
    • DOI 10.1111/j.1600-065X.2007.00547.x
    • Rohde, K., Yates, R. M., Purdy, G. E. & Russell, D. G. Mycobacterium tuberculosis and the environment within the phagosome. Immunol. Rev. 219, 37-54 (2007). (Pubitemid 47390002)
    • (2007) Immunological Reviews , vol.219 , Issue.1 , pp. 37-54
    • Rohde, K.1    Yates, R.M.2    Purdy, G.E.3    Russell, D.G.4
  • 36
    • 0035064072 scopus 로고    scopus 로고
    • Immunology of tuberculosis
    • DOI 10.1146/annurev.immunol.19.1.93
    • Flynn, J. L. & Chan, J. Immunology of tuberculosis. Annu. Rev. Immunol. 19, 93-129 (2001). (Pubitemid 32368031)
    • (2001) Annual Review of Immunology , vol.19 , pp. 93-129
    • Flynn, J.L.1    Chan, J.2
  • 37
    • 0033826580 scopus 로고    scopus 로고
    • Is the development of a new tuberculosis vaccine possible?
    • Kaufmann, S. H. Is the development of a new tuberculosis vaccine possible? Nature Med. 6, 955-960 (2000).
    • (2000) Nature Med. , vol.6 , pp. 955-960
    • Kaufmann, S.H.1
  • 38
    • 0036274370 scopus 로고    scopus 로고
    • Tuberculosis unleashed: The impact of human immunodeficiency virus infection on the host granulomatous response to Mycobacterium tuberculosis
    • DOI 10.1016/S1286-4579(02)01582-4, PII S1286457902015824
    • Lawn, S. D., Butera, S. T. & Shinnick, T. M. Tuberculosis unleashed: the impact of human immunodeficiency virus infection on the host granulomatous response to Mycobacterium tuberculosis. Microbes Infect. 4, 635-646 (2002). (Pubitemid 34614552)
    • (2002) Microbes and Infection , vol.4 , Issue.6 , pp. 635-646
    • Lawn, S.D.1    Butera, S.T.2    Shinnick, T.M.3
  • 39
    • 0027771385 scopus 로고
    • Granuloma formation in severe combined immunodeficient (SCID) mice in response to progressive BCG infection: Tendency not to form granulomas in the lung is associated with faster bacterial growth in this organ
    • North, R. J. & Izzo, A. A. Granuloma formation in severe combined immunodeficient (SCID) mice in response to progressive BCG infection. Tendency not to form granulomas in the lung is associated with faster bacterial growth in this organ. Am. J. Pathol. 142, 1959-1966 (1993). (Pubitemid 24057091)
    • (1993) American Journal of Pathology , vol.142 , Issue.6 , pp. 1959-1966
    • North, R.J.1    Izzo, A.A.2
  • 41
    • 0030790652 scopus 로고    scopus 로고
    • Interleukin 12 (IL-12) is crucial to the development of protective immunity in mice intravenously infected with mycobacterium tuberculosis
    • DOI 10.1084/jem.186.1.39
    • Cooper, A. M., Magram, J., Ferrante, J. & Orme, I. M. Interleukin 12 (IL-12) is crucial to the development of protective immunity in mice intravenously infected with Mycobacterium tuberculosis. J. Exp. Med. 186, 39-45 (1997). (Pubitemid 27304845)
    • (1997) Journal of Experimental Medicine , vol.186 , Issue.1 , pp. 39-45
    • Cooper, A.M.1    Magram, J.2    Ferrante, J.3    Orme, I.M.4
  • 43
    • 34548704962 scopus 로고    scopus 로고
    • IL-1 receptor-mediated signal is an essential component of MyD88-dependent innate response to Mycobacterium tuberculosis infection
    • Fremond, C. M. et al. IL-1 receptor-mediated signal is an essential component of MyD88-dependent innate response to Mycobacterium tuberculosis infection. J. Immunol. 179, 1178-1189 (2007).
    • (2007) J. Immunol. , vol.179 , pp. 1178-1189
    • Fremond, C.M.1
  • 45
    • 0033823682 scopus 로고    scopus 로고
    • Interleukin-1 signaling is essential for host defense during murine pulmonary tuberculosis
    • Juffermans, N. P. et al. Interleukin-1 signaling is essential for host defense during murine pulmonary tuberculosis. J. Infect. Dis. 182, 902-908 (2000).
    • (2000) J. Infect. Dis. , vol.182 , pp. 902-908
    • Juffermans, N.P.1
  • 46
    • 1842588021 scopus 로고    scopus 로고
    • MyD88-Deficient Mice Display A Profound Loss in Resistance to Mycobacterium tuberculosis Associated with Partially Impaired Th1 Cytokine and Nitric Oxide Synthase 2 Expression
    • DOI 10.1128/IAI.72.4.2400-2404.2004
    • Scanga, C. A. et al. MyD88-deficient mice display a profound loss in resistance to Mycobacterium tuberculosis associated with partially impaired Th1 cytokine and nitric oxide synthase 2 expression. Infect. Immun. 72, 2400-2404 (2004). (Pubitemid 38419959)
    • (2004) Infection and Immunity , vol.72 , Issue.4 , pp. 2400-2404
    • Scanga, C.A.1    Bafica, A.2    Feng, C.G.3    Cheever, A.W.4    Hieny, S.5    Sher, A.6
  • 47
    • 0037241835 scopus 로고    scopus 로고
    • Relative importance of STAT4 in murine tuberculosis
    • DOI 10.1099/jmm.0.05026-0
    • Sugawara, I., Yamada, H. & Mizuno, S. Relative importance of STAT4 in murine tuberculosis. J. Med. Microbiol. 52, 29-34 (2003). (Pubitemid 36106365)
    • (2003) Journal of Medical Microbiology , vol.52 , Issue.1 , pp. 29-34
    • Sugawara, I.1    Yamada, H.2    Mizuno, S.3
  • 48
    • 48749114458 scopus 로고    scopus 로고
    • Tumor necrosis factor signaling mediates resistance to mycobacteria by inhibiting bacterial growth and macrophage death
    • Clay, H., Volkman, H. E. & Ramakrishnan, L. Tumor necrosis factor signaling mediates resistance to mycobacteria by inhibiting bacterial growth and macrophage death. Immunity 29, 283-294 (2008).
    • (2008) Immunity , vol.29 , pp. 283-294
    • Clay, H.1    Volkman, H.E.2    Ramakrishnan, L.3
  • 49
    • 22544467821 scopus 로고    scopus 로고
    • Tumor necrosis factor and chemokine interactions in the formation and maintenance of granulomas in tuberculosis
    • DOI 10.1086/429994
    • Algood, H. M., Lin, P. L. & Flynn, J. L. Tumor necrosis factor and chemokine interactions in the formation and maintenance of granulomas in tuberculosis. Clin. Infect. Dis. 41, S189-S193 (2005). (Pubitemid 41022089)
    • (2005) Clinical Infectious Diseases , vol.41 , Issue.3 SUPPL.
    • Algood, H.M.S.1    Lin, P.L.2    Flynn, J.L.3
  • 50
    • 0033559125 scopus 로고    scopus 로고
    • Structural deficiencies in granuloma formation in TNF gene-targeted mice underlie the heightened susceptibility to aerosol Mycobacterium tuberculosis infection, which is not compensated for by lymphotoxin
    • Bean, A. G. et al. Structural deficiencies in granuloma formation in TNF gene-targeted mice underlie the heightened susceptibility to aerosol Mycobacterium tuberculosis infection, which is not compensated for by lymphotoxin. J. Immunol. 162, 3504-3511 (1999). (Pubitemid 29313602)
    • (1999) Journal of Immunology , vol.162 , Issue.6 , pp. 3504-3511
    • Bean, A.G.D.1    Roach, D.R.2    Briscoe, H.3    France, M.P.4    Korner, H.5    Sedgwick, J.D.6    Britton, W.J.7
  • 52
    • 0028979703 scopus 로고
    • Tumor necrosis factor-α is required in the protective immune response against Mycobacterium tuberculosis in mice
    • Flynn, J. L. et al. Tumor necrosis factor-α is required in the protective immune response against Mycobacterium tuberculosis in mice. Immunity 2, 561-572 (1995).
    • (1995) Immunity , vol.2 , pp. 561-572
    • Flynn, J.L.1
  • 53
    • 0024566140 scopus 로고
    • The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection
    • DOI 10.1016/0092-8674(89)90676-4
    • Kindler, V., Sappino, A. P., Grau, G. E., Piguet, P. F. & Vassalli, P. The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection. Cell 56, 731-740 (1989). (Pubitemid 19082507)
    • (1989) Cell , vol.56 , Issue.5 , pp. 731-740
    • Kindler, V.1    Sappino, A.-P.2    Grau, G.E.3    Piguet, P.-F.4    Vassalli, P.5
  • 54
    • 0036569910 scopus 로고    scopus 로고
    • TNF regulates chemokine induction essential for cell recruitment, granuloma formation, and clearance of mycobacterial infection
    • Roach, D. R. et al. TNF regulates chemokine induction essential for cell recruitment, granuloma formation, and clearance of mycobacterial infection. J. Immunol. 168, 4620-4627 (2002). (Pubitemid 34441368)
    • (2002) Journal of Immunology , vol.168 , Issue.9 , pp. 4620-4627
    • Roach, D.R.1    Bean, A.G.D.2    Demangel, C.3    France, M.P.4    Briscoe, H.5    Britton, W.J.6
  • 55
    • 27444432605 scopus 로고    scopus 로고
    • Immunological control of tuberculosis: Role of tumour necrosis factor and more
    • DOI 10.1136/ard.2005.042531
    • Stenger, S. Immunological control of tuberculosis: role of tumour necrosis factor and more. Ann. Rheum. Dis. 64, iv24-iv28 (2005). (Pubitemid 41532012)
    • (2005) Annals of the Rheumatic Diseases , vol.64 , Issue.SUPPL. 4
    • Stenger, S.1
  • 56
    • 0027471981 scopus 로고
    • Immunopathogenesis of pulmonary tuberculosis
    • Dannenberg, A. M. Jr. Immunopathogenesis of pulmonary tuberculosis. Hosp. Pract. 28, 51-58 (1993). (Pubitemid 23029754)
    • (1993) Hospital Practice , vol.28 , Issue.1 , pp. 51-58
    • Dannenberg Jr., A.M.1
  • 57
    • 34848910546 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis infects dendritic cells with high frequency and impairs their function in vivo
    • Wolf, A. J. et al. Mycobacterium tuberculosis infects dendritic cells with high frequency and impairs their function in vivo. J. Immunol. 179, 2509-2519 (2007).
    • (2007) J. Immunol. , vol.179 , pp. 2509-2519
    • Wolf, A.J.1
  • 58
    • 38749138163 scopus 로고    scopus 로고
    • Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs
    • DOI 10.1084/jem.20071367
    • Wolf, A. J. et al. Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs. J. Exp. Med. 205, 105-115 (2008). (Pubitemid 351185719)
    • (2008) Journal of Experimental Medicine , vol.205 , Issue.1 , pp. 105-115
    • Wolf, A.J.1    Desvignes, L.2    Linas, B.3    Banaiee, N.4    Tamura, T.5    Takatsu, K.6    Ernst, J.D.7
  • 59
    • 0030743238 scopus 로고    scopus 로고
    • Mycobacterium marinum infection of the hand
    • DOI 10.1056/NEJM199708283370906
    • Ramakrishnan, L. Images in clinical medicine. Mycobacterium marinum infection of the hand. N. Engl. J. Med. 337, 612 (1997). (Pubitemid 27360762)
    • (1997) New England Journal of Medicine , vol.337 , Issue.9 , pp. 612
    • Ramakrishnan, L.1
  • 60
    • 2542480887 scopus 로고    scopus 로고
    • Immunity to tuberculosis
    • DOI 10.1146/annurev.immunol.22.012703.104635
    • North, R. J. & Jung, Y. J. Immunity to tuberculosis. Annu. Rev. Immunol. 22, 599-623 (2004). (Pubitemid 38680435)
    • (2004) Annual Review of Immunology , vol.22 , pp. 599-623
    • North, R.J.1    Jung, Y.-J.2
  • 61
    • 33750439462 scopus 로고    scopus 로고
    • Mycobacterium marinum infection of adult zebrafish causes caseating granulomatous tuberculosis and is moderated by adaptive immunity
    • DOI 10.1128/IAI.00887-06
    • Swaim, L. E. et al. Mycobacterium marinum infection of adult zebrafish causes caseating granulomatous tuberculosis and is moderated by adaptive immunity. Infect. Immun. 74, 6108-6117 (2006). (Pubitemid 44657389)
    • (2006) Infection and Immunity , vol.74 , Issue.11 , pp. 6108-6117
    • Swaim, L.E.1    Connolly, L.E.2    Volkman, H.E.3    Humbert, O.4    Born, D.E.5    Ramakrishnan, L.6
  • 62
    • 0031034737 scopus 로고    scopus 로고
    • Host responses and antigens involved in protective immunity to Mycobacterium tuberculosis
    • Andersen, P. Host responses and antigens involved in protective immunity to Mycobacterium tuberculosis. Scand. J. Immunol. 45, 115-131 (1997). (Pubitemid 27047240)
    • (1997) Scandinavian Journal of Immunology , vol.45 , Issue.2 , pp. 115-131
    • Andersen, P.1
  • 63
    • 0033846833 scopus 로고    scopus 로고
    • Restraining mycobacteria: Role of granulomas in mycobacterial infections
    • DOI 10.1046/j.1440-1711.2000.00933.x
    • Saunders, B. M. & Cooper, A. M. Restraining mycobacteria: role of granulomas in mycobacterial infections. Immunol. Cell Biol. 78, 334-341 (2000). (Pubitemid 30655559)
    • (2000) Immunology and Cell Biology , vol.78 , Issue.4 , pp. 334-341
    • Saunders, B.M.1    Cooper, A.M.2
  • 64
    • 58149083837 scopus 로고    scopus 로고
    • The role of the granuloma in expansion and dissemination of early tuberculous infection
    • Davis, J. M. & Ramakrishnan, L. The role of the granuloma in expansion and dissemination of early tuberculous infection. Cell 136, 37-49 (2009).
    • (2009) Cell , vol.136 , pp. 37-49
    • Davis, J.M.1    Ramakrishnan, L.2
  • 65
    • 14044254749 scopus 로고    scopus 로고
    • Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant
    • Volkman, H. E. et al. Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant. PLoS Biol. 2, e367 (2004).
    • (2004) PLoS Biol. , vol.2
    • Volkman, H.E.1
  • 66
    • 18744363879 scopus 로고    scopus 로고
    • Real-time visualization of Mycobacterium-macrophage interactions leading to initiation of granuloma formation in zebrafish embryos
    • DOI 10.1016/S1074-7613(02)00475-2
    • Davis, J. M. et al. Real-time visualization of mycobacterium-macrophage interactions leading to initiation of granuloma formation in zebrafish embryos. Immunity 17, 693-702 (2002). (Pubitemid 35477789)
    • (2002) Immunity , vol.17 , Issue.6 , pp. 693-702
    • Davis, J.M.1    Clay, H.2    Lewis, J.L.3    Ghori, N.4    Herbomel, P.5    Ramakrishnan, L.6
  • 67
    • 33645866471 scopus 로고    scopus 로고
    • Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell-dendritic cell interaction
    • Castellino, F. et al. Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell-dendritic cell interaction. Nature 440, 890-895 (2006).
    • (2006) Nature , vol.440 , pp. 890-895
    • Castellino, F.1
  • 68
    • 21844450539 scopus 로고    scopus 로고
    • Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells
    • Okada, T. et al. Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells. PLoS Biol. 3, e150 (2005).
    • (2005) PLoS Biol. , vol.3
    • Okada, T.1
  • 71
    • 0037036114 scopus 로고    scopus 로고
    • Dynamic imaging of T cell-dendritic cell interactions in lymph nodes
    • DOI 10.1126/science.1071065
    • Stoll, S., Delon, J., Brotz, T. M. & Germain, R. N. Dynamic imaging of T cell-dendritic cell interactions in lymph nodes. Science 296, 1873-1876 (2002). (Pubitemid 34596274)
    • (2002) Science , vol.296 , Issue.5574 , pp. 1873-1876
    • Stoll, S.1    Delon, J.2    Brotz, T.M.3    Germain, R.N.4
  • 72
    • 38949096968 scopus 로고    scopus 로고
    • Macrophage and T cell dynamics during the development and disintegration of mycobacterial granulomas
    • Egen, J. G. et al. Macrophage and T cell dynamics during the development and disintegration of mycobacterial granulomas. Immunity 28, 271-284 (2008).
    • (2008) Immunity , vol.28 , pp. 271-284
    • Egen, J.G.1
  • 73
    • 79956302280 scopus 로고    scopus 로고
    • Intravital imaging reveals limited antigen presentation and T cell effector function in mycobacterial granulomas
    • Egen, J. G. et al. Intravital imaging reveals limited antigen presentation and T cell effector function in mycobacterial granulomas. Immunity 34, 807-819 (2011).
    • (2011) Immunity , vol.34 , pp. 807-819
    • Egen, J.G.1
  • 74
    • 3042803777 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis H37Rv:δRD1 is more virulent than M. bovis Bacille Calmette-Guérin in long-term murine infection
    • DOI 10.1086/421472
    • Sherman, D. R. et al. Mycobacterium tuberculosis H37Rv:ΔRD1 is more virulent than M. bovis bacille Calmette-Guerin in long-term murine infection. J. Infect. Dis. 190, 123-126 (2004). (Pubitemid 38858412)
    • (2004) Journal of Infectious Diseases , vol.190 , Issue.1 , pp. 123-126
    • Sherman, D.R.1    Guinn, K.M.2    Hickey, M.J.3    Mathur, S.K.4    Zakel, K.L.5    Smith, S.6
  • 75
    • 4444264777 scopus 로고    scopus 로고
    • Superinfecting mycobacteria home to established tuberculous granulomas
    • DOI 10.1038/ni1091
    • Cosma, C. L., Humbert, O. & Ramakrishnan, L. Superinfecting mycobacteria home to established tuberculous granulomas. Nature Immunol. 5, 828-835 (2004). (Pubitemid 39172976)
    • (2004) Nature Immunology , vol.5 , Issue.8 , pp. 828-835
    • Cosma, C.L.1    Humbert, O.2    Ramakrishnan, L.3
  • 76
    • 0042161748 scopus 로고    scopus 로고
    • Macrophage turnover, division and activation within developing, peak and "healed" tuberculous lesions produced in rabbits by BCG
    • DOI 10.1016/S1472-9792(03)00048-9
    • Dannenberg, A. M. Jr. Macrophage turnover, division and activation within developing, peak and "healed" tuberculous lesions produced in rabbits by BCG. Tuberculosis 83, 251-260 (2003). (Pubitemid 36995247)
    • (2003) Tuberculosis , vol.83 , Issue.4 , pp. 251-260
    • Dannenberg Jr., A.M.1
  • 77
    • 0034641931 scopus 로고    scopus 로고
    • Corpse clearance defines the meaning of cell death
    • Savill, J. & Fadok, V. Corpse clearance defines the meaning of cell death. Nature 407, 784-788 (2000).
    • (2000) Nature , vol.407 , pp. 784-788
    • Savill, J.1    Fadok, V.2
  • 78
    • 39749182234 scopus 로고    scopus 로고
    • Apoptosis: Controlled demolition at the cellular level
    • DOI 10.1038/nrm2312, PII NRM2312
    • Taylor, R. C., Cullen, S. P. & Martin, S. J. Apoptosis: controlled demolition at the cellular level. Nature Rev. Mol. Cell Biol. 9, 231-241 (2008). (Pubitemid 351301823)
    • (2008) Nature Reviews Molecular Cell Biology , vol.9 , Issue.3 , pp. 231-241
    • Taylor, R.C.1    Cullen, S.P.2    Martin, S.J.3
  • 79
  • 80
    • 65449166781 scopus 로고    scopus 로고
    • Synergy between individual TNF-dependent functions determines granuloma performance for controlling Mycobacterium tuberculosis infection
    • Ray, J. C., Flynn, J. L. & Kirschner, D. E. Synergy between individual TNF-dependent functions determines granuloma performance for controlling Mycobacterium tuberculosis infection. J. Immunol. 182, 3706-3717 (2009).
    • (2009) J. Immunol. , vol.182 , pp. 3706-3717
    • Ray, J.C.1    Flynn, J.L.2    Kirschner, D.E.3
  • 81
    • 75749099727 scopus 로고    scopus 로고
    • Tumor necrosis factor neutralization results in disseminated disease in acute and latent Mycobacterium tuberculosis infection with normal granuloma structure in a cynomolgus macaque model
    • Lin, P. L. et al. Tumor necrosis factor neutralization results in disseminated disease in acute and latent Mycobacterium tuberculosis infection with normal granuloma structure in a cynomolgus macaque model. Arthritis Rheum. 62, 340-350 (2010).
    • (2010) Arthritis Rheum. , vol.62 , pp. 340-350
    • Lin, P.L.1
  • 82
    • 15044361763 scopus 로고    scopus 로고
    • Paradoxical response to antituberculous therapy in infliximab-treated patients with disseminated tuberculosis
    • Garcia Vidal, C. et al. Paradoxical response to antituberculous therapy in infliximab-treated patients with disseminated tuberculosis. Clin. Infect. Dis. 40, 756-759 (2005).
    • (2005) Clin. Infect. Dis. , vol.40 , pp. 756-759
    • Garcia Vidal, C.1
  • 85
    • 33644516283 scopus 로고    scopus 로고
    • Potent inhibition of macrophage responses to IFN-γ by live virulent Mycobacterium tuberculosis is independent of mature mycobacterial lipoproteins but dependent on TLR2
    • Banaiee, N., Kincaid, E. Z., Buchwald, U., Jacobs, W. R. Jr & Ernst, J. D. Potent inhibition of macrophage responses to IFN-γ by live virulent Mycobacterium tuberculosis is independent of mature mycobacterial lipoproteins but dependent on TLR2. J. Immunol. 176, 3019-3027 (2006).
    • (2006) J. Immunol. , vol.176 , pp. 3019-3027
    • Banaiee, N.1    Kincaid, E.Z.2    Buchwald, U.3    Jacobs Jr., W.R.4    Ernst, J.D.5
  • 87
    • 0042635767 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis exerts gene-selective inhibition of transcriptional responses to IFN-γ without inhibiting STAT1 function
    • Kincaid, E. Z. & Ernst, J. D. Mycobacterium tuberculosis exerts gene-selective inhibition of transcriptional responses to IFN-γ without inhibiting STAT1 function. J. Immunol. 171, 2042-2049 (2003). (Pubitemid 36966487)
    • (2003) Journal of Immunology , vol.171 , Issue.4 , pp. 2042-2049
    • Kincaid, E.Z.1    Ernst, J.D.2
  • 88
    • 0033214553 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis inhibits IFN-γ transcriptional responses without inhibiting activation of STAT1
    • Ting, L. M., Kim, A. C., Cattamanchi, A. & Ernst, J. D. Mycobacterium tuberculosis inhibits IFN-γ transcriptional responses without inhibiting activation of STAT1. J. Immunol. 163, 3898-3906 (1999). (Pubitemid 29450917)
    • (1999) Journal of Immunology , vol.163 , Issue.7 , pp. 3898-3906
    • Ting, L.-M.1    Kim, A.C.2    Cattamanchi, A.3    Ernst, J.D.4
  • 89
    • 66949159845 scopus 로고    scopus 로고
    • Transcriptome profiling and functional analyses of the zebrafish embryonic innate immune response to Salmonella infection
    • Stockhammer, O. W., Zakrzewska, A., Hegedus, Z., Spaink, H. P. & Meijer, A. H. Transcriptome profiling and functional analyses of the zebrafish embryonic innate immune response to Salmonella infection. J. Immunol. 182, 5641-5653 (2009).
    • (2009) J. Immunol. , vol.182 , pp. 5641-5653
    • Stockhammer, O.W.1    Zakrzewska, A.2    Hegedus, Z.3    Spaink, H.P.4    Meijer, A.H.5
  • 90
    • 77649128120 scopus 로고    scopus 로고
    • The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans
    • Tobin, D. M. et al. The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans. Cell 140, 717-730 (2010).
    • (2010) Cell , vol.140 , pp. 717-730
    • Tobin, D.M.1
  • 92
    • 17844408723 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinase-9 in pleural effusions of tuberculosis and lung cancer
    • DOI 10.1159/000084048
    • Park, K. J. et al. Expression of matrix metalloproteinase-9 in pleural effusions of tuberculosis and lung cancer. Respiration 72, 166-175 (2005). (Pubitemid 40591530)
    • (2005) Respiration , vol.72 , Issue.2 , pp. 166-175
    • Park, K.J.1    Hwang, S.C.2    Sheen, S.S.3    Oh, Y.J.4    Han, J.H.5    Lee, K.B.6
  • 94
    • 58849088869 scopus 로고    scopus 로고
    • High MMP-9 activity characterises pleural tuberculosis correlating with granuloma formation
    • Sheen, P. et al. High MMP-9 activity characterises pleural tuberculosis correlating with granuloma formation. Eur. Respir. J. 33, 134-141 (2009).
    • (2009) Eur. Respir. J. , vol.33 , pp. 134-141
    • Sheen, P.1
  • 96
    • 79953279193 scopus 로고    scopus 로고
    • Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism
    • Adams, K. N. et al. Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism. Cell 145, 39-53 (2011).
    • (2011) Cell , vol.145 , pp. 39-53
    • Adams, K.N.1
  • 97
    • 0034502343 scopus 로고    scopus 로고
    • Persistence of DNA from Mycobacterium tuberculosis in superficially normal lung tissue during latent infection
    • Hernandez-Pando, R. et al. Persistence of DNA from Mycobacterium tuberculosis in superficially normal lung tissue during latent infection. Lancet 356, 2133-2138 (2000).
    • (2000) Lancet , vol.356 , pp. 2133-2138
    • Hernandez-Pando, R.1
  • 98
    • 0028241565 scopus 로고
    • Pathogenesis of tuberculosis: Pathway to apical localization
    • DOI 10.1016/0962-8479(94)90002-7
    • Balasubramanian, V., Wiegeshaus, E. H., Taylor, B. T. & Smith, D. W. Pathogenesis of tuberculosis: pathway to apical localization. Tuber. Lung Dis. 75, 168-178 (1994). (Pubitemid 24217271)
    • (1994) Tubercle and Lung Disease , vol.75 , Issue.3 , pp. 168-178
    • Balasubramanian, V.1    Wiegeshaus, E.H.2    Taylor, B.T.3    Smith, D.W.4
  • 99
    • 0036078710 scopus 로고    scopus 로고
    • Dissemination of Mycobacterium tuberculosis is influenced by host factors and precedes the initiation of T-cell immunity
    • DOI 10.1128/IAI.70.8.4501-4509.2002
    • Chackerian, A. A., Alt, J. M., Perera, T. V., Dascher, C. C. & Behar, S. M. Dissemination of Mycobacterium tuberculosis is influenced by host factors and precedes the initiation of T-cell immunity. Infect. Immun. 70, 4501-4509 (2002). (Pubitemid 34790962)
    • (2002) Infection and Immunity , vol.70 , Issue.8 , pp. 4501-4509
    • Chackerian, A.A.1    Alt, J.M.2    Perera, T.V.3    Dascher, C.C.4    Behar, S.M.5
  • 100
    • 80053429660 scopus 로고    scopus 로고
    • Inflammatory dendritic cells migrate in and out of transplanted chronic mycobacterial granulomas in mice
    • Schreiber, H. A. et al. Inflammatory dendritic cells migrate in and out of transplanted chronic mycobacterial granulomas in mice. J. Clin. Invest. 121, 3902-3913 (2011).
    • (2011) J. Clin. Invest. , vol.121 , pp. 3902-3913
    • Schreiber, H.A.1
  • 101
    • 79952203201 scopus 로고    scopus 로고
    • Immunopathology of postprimary tuberculosis: Increased T-regulatory cells and DEC-205-positive foamy macrophages in cavitary lesions
    • 307631
    • Welsh, K. J., Risin, S. A., Actor, J. K. & Hunter, R. L. Immunopathology of postprimary tuberculosis: increased T-regulatory cells and DEC-205-positive foamy macrophages in cavitary lesions. Clin. Dev. Immunol. 2011, 307631 (2011).
    • (2011) Clin. Dev. Immunol.
    • Welsh, K.J.1    Risin, S.A.2    Actor, J.K.3    Hunter, R.L.4
  • 102
    • 0034463942 scopus 로고    scopus 로고
    • Transient radiographic progression during initial treatment of pulmonary tuberculosis: CT findings
    • DOI 10.1097/00004728-200005000-00014
    • Akira, M., Sakatani, M. & Ishikawa, H. Transient radiographic progression during initial treatment of pulmonary tuberculosis: CT findings. J. Comput. Assist. Tomogr. 24, 426-431 (2000). (Pubitemid 32203936)
    • (2000) Journal of Computer Assisted Tomography , vol.24 , Issue.3 , pp. 426-431
    • Akira, M.1    Sakatani, M.2    Ishikawa, H.3
  • 103
    • 0018903350 scopus 로고
    • Reversible roentgenographic progression in the initial treatment of pulmonary tuberculosis
    • Bobrowitz, I. D. Reversible roentgenographic progression in the initial treatment of pulmonary tuberculosis. Am. Rev. Respir. Dis. 121, 735-742 (1980). (Pubitemid 10150588)
    • (1980) American Review of Respiratory Disease , vol.121 , Issue.4 , pp. 735-742
    • Bobrowitz, I.D.1
  • 107
    • 84856693171 scopus 로고    scopus 로고
    • Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections
    • Tobin, D. et al. Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections. Cell 148, 434-446 (2012).
    • (2012) Cell , vol.148 , pp. 434-446
    • Tobin, D.1
  • 108
    • 58149296186 scopus 로고    scopus 로고
    • Lipid mediators in innate immunity against tuberculosis: Opposing roles of PGE2 and LXA4 in the induction of macrophage death
    • Chen, M. et al. Lipid mediators in innate immunity against tuberculosis: opposing roles of PGE2 and LXA4 in the induction of macrophage death. J. Exp. Med. 205, 2791-2801 (2008).
    • (2008) J. Exp. Med. , vol.205 , pp. 2791-2801
    • Chen, M.1
  • 109
    • 79955082538 scopus 로고    scopus 로고
    • Apoptosis is an innate defense function of macrophages against Mycobacterium tuberculosis
    • Behar, S. M. et al. Apoptosis is an innate defense function of macrophages against Mycobacterium tuberculosis. Mucosal Immunol. 4, 279-287 (2011).
    • (2011) Mucosal Immunol. , vol.4 , pp. 279-287
    • Behar, S.M.1
  • 110
    • 0031133280 scopus 로고    scopus 로고
    • Programmed Cell Death of Mycobacterium avium Serovar 4-Infected Human Macrophages Prevents the Mycobacteria from Spreading and Induces Mycobacterial Growth Inhibition by Freshly Added, Uninfected Macrophages
    • Fratazzi, C., Arbeit, R. D., Carini, C. & Remold, H. G. Programmed cell death of Mycobacterium avium serovar 4-infected human macrophages prevents the mycobacteria from spreading and induces mycobacterial growth inhibition by freshly added, uninfected macrophages. J. Immunol. 158, 4320-4327 (1997). (Pubitemid 127483933)
    • (1997) Journal of Immunology , vol.158 , Issue.9 , pp. 4320-4327
    • Fratazzi, C.1    Arbeit, R.D.2    Carini, C.3    Remold, H.G.4
  • 111
    • 52549123569 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis blocks crosslinking of annexin-1 and apoptotic envelope formation on infected macrophages to maintain virulence
    • Gan, H. et al. Mycobacterium tuberculosis blocks crosslinking of annexin-1 and apoptotic envelope formation on infected macrophages to maintain virulence. Nature Immunol. 9, 1189-1197 (2008).
    • (2008) Nature Immunol. , vol.9 , pp. 1189-1197
    • Gan, H.1
  • 112
    • 0036395920 scopus 로고    scopus 로고
    • TNF-dependent BALB/c murine macrophage apoptosis following Mycobacterium tuberculosis infection inhibits bacillary growth in an IFN-γ independent manner
    • DOI 10.1054/tube.2002.0322
    • Keane, J., Shurtleff, B. & Kornfeld, H. TNF-dependent BALB/c murine macrophage apoptosis following Mycobacterium tuberculosis infection inhibits bacillary growth in an IFN-γ independent manner. Tuberculosis 82, 55-61 (2002). (Pubitemid 35155419)
    • (2002) Tuberculosis , vol.82 , Issue.2-3 , pp. 55-61
    • Keane, J.1    Shurtleff, B.2    Kornfeld, H.3
  • 113
    • 0032103037 scopus 로고    scopus 로고
    • Fas ligand-induced apoptosis of infected human macrophages reduces the viability of intracellular Mycobacterium tuberculosis
    • Oddo, M. et al. Fas ligand-induced apoptosis of infected human macrophages reduces the viability of intracellular Mycobacterium tuberculosis. J. Immunol. 160, 5448-5454 (1998). (Pubitemid 28267836)
    • (1998) Journal of Immunology , vol.160 , Issue.11 , pp. 5448-5454
    • Oddo, M.1    Renno, T.2    Attinger, A.3    Bakker, T.4    MacDonald, H.R.5    Meylan, P.R.A.6
  • 114
    • 4644320227 scopus 로고    scopus 로고
    • A mycobacterial virulence gene cluster extending RD1 is required for cytolysis, bacterial spreading and ESAT-6 secretion
    • Gao, L. Y. et al. A mycobacterial virulence gene cluster extending RD1 is required for cytolysis, bacterial spreading and ESAT-6 secretion. Mol. Microbiol. 53, 1677-1693 (2004).
    • (2004) Mol. Microbiol. , vol.53 , pp. 1677-1693
    • Gao, L.Y.1
  • 116
    • 77952956465 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress response is involved in Mycobacterium tuberculosis protein ESAT-6-mediated apoptosis
    • Choi, H. H. et al. Endoplasmic reticulum stress response is involved in Mycobacterium tuberculosis protein ESAT-6-mediated apoptosis. FEBS Lett. 584, 2445-2454 (2010).
    • (2010) FEBS Lett. , vol.584 , pp. 2445-2454
    • Choi, H.H.1
  • 117
    • 34248671986 scopus 로고    scopus 로고
    • The ESAT6 protein of Mycobacterium tuberculosis induces apoptosis of macrophages by activating caspase expression
    • DOI 10.1111/j.1462-5822.2007.00892.x
    • Derrick, S. C. & Morris, S. L. The ESAT6 protein of Mycobacterium tuberculosis induces apoptosis of macrophages by activating caspase expression. Cell. Microbiol. 9, 1547-1555 (2007). (Pubitemid 46774025)
    • (2007) Cellular Microbiology , vol.9 , Issue.6 , pp. 1547-1555
    • Derrick, S.C.1    Morris, S.L.2
  • 118
    • 77957133396 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome
    • Mishra, B. B. et al. Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome. Cell. Microbiol. 12, 1046-1063 (2010).
    • (2010) Cell. Microbiol. , vol.12 , pp. 1046-1063
    • Mishra, B.B.1
  • 119
    • 0028136987 scopus 로고
    • Apoptosis but not necrosis, of infected monocytes is coupled with killing of intracellular bacillus Calmette-Guerin
    • Molloy, A., Laochumroonvorapong, P. & Kaplan, G. Apoptosis, but not necrosis, of infected monocytes is coupled with killing of intracellular bacillus Calmette-Guerin. J. Exp. Med. 180, 1499-1509 (1994).
    • (1994) J. Exp. Med. , vol.180 , pp. 1499-1509
    • Molloy, A.1    Laochumroonvorapong, P.2    Kaplan, G.3
  • 121
    • 48649102274 scopus 로고    scopus 로고
    • Living on the edge: Inhibition of host cell apoptosis by Mycobacterium tuberculosis
    • Briken, V. & Miller, J. L. Living on the edge: inhibition of host cell apoptosis by Mycobacterium tuberculosis. Future Microbiol. 3, 415-422 (2008).
    • (2008) Future Microbiol. , vol.3 , pp. 415-422
    • Briken, V.1    Miller, J.L.2
  • 123
    • 38049097940 scopus 로고    scopus 로고
    • Protein kinase e of Mycobacterium tuberculosis has a role in the nitric oxide stress response and apoptosis in a human macrophage model of infection
    • Jayakumar, D., Jacobs, W. R. Jr & Narayanan, S. Protein kinase E of Mycobacterium tuberculosis has a role in the nitric oxide stress response and apoptosis in a human macrophage model of infection. Cell. Microbiol. 10, 365-374 (2008).
    • (2008) Cell. Microbiol. , vol.10 , pp. 365-374
    • Jayakumar, D.1    Jacobs Jr., W.R.2    Narayanan, S.3
  • 124
    • 34547642553 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis nuoG is a virulence gene that inhibits apoptosis of infected host cells
    • Velmurugan, K. et al. Mycobacterium tuberculosis nuoG is a virulence gene that inhibits apoptosis of infected host cells. PLoS Pathog. 3, e110 (2007).
    • (2007) PLoS Pathog. , vol.3
    • Velmurugan, K.1
  • 125
    • 77954064664 scopus 로고    scopus 로고
    • The type i NADH dehydrogenase of Mycobacterium tuberculosis counters phagosomal NOX2 activity to inhibit TNF-α-mediated host cell apoptosis
    • Miller, J. L., Velmurugan, K., Cowan, M. J. & Briken, V. The type I NADH dehydrogenase of Mycobacterium tuberculosis counters phagosomal NOX2 activity to inhibit TNF-α-mediated host cell apoptosis. PLoS Pathog. 6, e1000864 (2010).
    • (2010) PLoS Pathog. , vol.6
    • Miller, J.L.1    Velmurugan, K.2    Cowan, M.J.3    Briken, V.4
  • 127
    • 67651171188 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair
    • Divangahi, M. et al. Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair. Nature Immunol. 10, 899-906 (2009).
    • (2009) Nature Immunol. , vol.10 , pp. 899-906
    • Divangahi, M.1
  • 128
    • 0036403086 scopus 로고    scopus 로고
    • CD4 is required for the development of a protective granulomatous response to pulmonary tuberculosis
    • DOI 10.1016/S0008-8749(02)00510-5, PII S0008874902005105
    • Saunders, B. M., Frank, A. A., Orme, I. M. & Cooper, A. M. CD4 is required for the development of a protective granulomatous response to pulmonary tuberculosis. Cell. Immunol. 216, 65-72 (2002). (Pubitemid 35193446)
    • (2002) Cellular Immunology , vol.216 , Issue.1-2 , pp. 65-72
    • Saunders, B.M.1    Frank, A.A.2    Orme, I.M.3    Cooper, A.M.4
  • 129
    • 67650932256 scopus 로고    scopus 로고
    • Cell-mediated immune responses in tuberculosis
    • Cooper, A. M. Cell-mediated immune responses in tuberculosis. Annu. Rev. Immunol. 27, 393-422 (2009).
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 393-422
    • Cooper, A.M.1
  • 130
    • 0344289512 scopus 로고    scopus 로고
    • Exogenous reinfection as a cause of recurrent tuberculosis after curative treatment
    • Van Rie, A. et al. Exogenous reinfection as a cause of recurrent tuberculosis after curative treatment. New Engl. J. Med. 341, 1174-1179 (1999).
    • (1999) New Engl. J. Med. , vol.341 , pp. 1174-1179
    • Van Rie, A.1
  • 133
    • 0035495579 scopus 로고    scopus 로고
    • How can immunology contribute to the control of tuberculosis?
    • Kaufmann, S. H. How can immunology contribute to the control of tuberculosis? Nature Rev. Immunol. 1, 20-30 (2001). (Pubitemid 33741972)
    • (2001) Nature Reviews Immunology , vol.1 , Issue.1 , pp. 20-30
    • Kaufmann, S.H.E.1
  • 134
    • 56749148643 scopus 로고    scopus 로고
    • Trafficking of superinfecting Mycobacterium organisms into established granulomas occurs in mammals and is independent of the Erp and ESX-1 mycobacterial virulence loci
    • Cosma, C. L., Humbert, O., Sherman, D. R. & Ramakrishnan, L. Trafficking of superinfecting Mycobacterium organisms into established granulomas occurs in mammals and is independent of the Erp and ESX-1 mycobacterial virulence loci. J. Infect. Dis. 198, 1851-1855 (2008).
    • (2008) J. Infect. Dis. , vol.198 , pp. 1851-1855
    • Cosma, C.L.1    Humbert, O.2    Sherman, D.R.3    Ramakrishnan, L.4
  • 135
    • 53349118087 scopus 로고    scopus 로고
    • Delayed protection by ESAT-6-specific effector CD4+ T cells after airborne M. tuberculosis infection
    • Gallegos, A. M., Pamer, E. G. & Glickman, M. S. Delayed protection by ESAT-6-specific effector CD4+ T cells after airborne M. tuberculosis infection. J. Exp. Med. 205, 2359-2368 (2008).
    • (2008) J. Exp. Med. , vol.205 , pp. 2359-2368
    • Gallegos, A.M.1    Pamer, E.G.2    Glickman, M.S.3
  • 136
    • 59649119960 scopus 로고    scopus 로고
    • A replication clock for Mycobacterium tuberculosis
    • Gill, W. P. et al. A replication clock for Mycobacterium tuberculosis. Nature Med. 15, 211-214 (2009).
    • (2009) Nature Med. , vol.15 , pp. 211-214
    • Gill, W.P.1
  • 137
    • 77954390239 scopus 로고    scopus 로고
    • Pathogen-specific regulatory T cells delay the arrival of effector T cells in the lung during early tuberculosis
    • Shafiani, S., Tucker-Heard, G., Kariyone, A., Takatsu, K. & Urdahl, K. B. Pathogen-specific regulatory T cells delay the arrival of effector T cells in the lung during early tuberculosis. J. Exp. Med. 207, 1409-1420 (2010).
    • (2010) J. Exp. Med. , vol.207 , pp. 1409-1420
    • Shafiani, S.1    Tucker-Heard, G.2    Kariyone, A.3    Takatsu, K.4    Urdahl, K.B.5
  • 141
    • 77955385939 scopus 로고    scopus 로고
    • Enhanced protection to Mycobacterium tuberculosis infection in IL-10-deficient mice is accompanied by early and enhanced Th1 responses in the lung
    • Redford, P. S. et al. Enhanced protection to Mycobacterium tuberculosis infection in IL-10-deficient mice is accompanied by early and enhanced Th1 responses in the lung. Eur. J. Immunol. 40, 2200-2210 (2010).
    • (2010) Eur. J. Immunol. , vol.40 , pp. 2200-2210
    • Redford, P.S.1
  • 142
    • 0027239981 scopus 로고
    • + T cells of mycobacteria growing in human macrophages
    • Pancholi, P., Mirza, A., Bhardwaj, N. & Steinman, R. M. Sequestration from immune CD4+ T cells of mycobacteria growing in human macrophages. Science 260, 984-986 (1993). (Pubitemid 23209972)
    • (1993) Science , vol.260 , Issue.5110 , pp. 984-986
    • Pancholi, P.1    Mirza, A.2    Bhardwaj, N.3    Steinman, R.M.4
  • 143
    • 79958073315 scopus 로고    scopus 로고
    • Suboptimal activation of antigen-specific CD4+ effector cells enables persistence of M. tuberculosis in vivo
    • Bold, T. D., Banaei, N., Wolf, A. J. & Ernst, J. D. Suboptimal activation of antigen-specific CD4+ effector cells enables persistence of M. tuberculosis in vivo. PLoS Pathog. 7, e1002063 (2011).
    • (2011) PLoS Pathog. , vol.7
    • Bold, T.D.1    Banaei, N.2    Wolf, A.J.3    Ernst, J.D.4
  • 144
    • 0142241439 scopus 로고    scopus 로고
    • Innate Inhibition of Adaptive Immunity: Mycobacterium tuberculosis-Induced IL-6 Inhibits Macrophage Responses to IFN-γ
    • Nagabhushanam, V. et al. Innate inhibition of adaptive immunity: Mycobacterium tuberculosis-induced IL-6 inhibits macrophage responses to IFN-γ. J. Immunol. 171, 4750-4757 (2003). (Pubitemid 37310593)
    • (2003) Journal of Immunology , vol.171 , Issue.9 , pp. 4750-4757
    • Nagabhushanam, V.1    Solache, A.2    Ting, L.-M.3    Escaron, C.J.4    Zhang, J.Y.5    Ernst, J.D.6
  • 145
    • 0034157346 scopus 로고    scopus 로고
    • Trafficking and release of mycobacterial lipids from infected macrophages
    • Beatty, W. L. et al. Trafficking and release of mycobacterial lipids from infected macrophages. Traffic 1, 235-247 (2000).
    • (2000) Traffic , vol.1 , pp. 235-247
    • Beatty, W.L.1
  • 146
    • 71749103051 scopus 로고    scopus 로고
    • Interferon-γ-responsive nonhematopoietic cells regulate the immune response to Mycobacterium tuberculosis
    • Desvignes, L. & Ernst, J. D. Interferon-γ-responsive nonhematopoietic cells regulate the immune response to Mycobacterium tuberculosis. Immunity 31, 974-985 (2009).
    • (2009) Immunity , vol.31 , pp. 974-985
    • Desvignes, L.1    Ernst, J.D.2
  • 147
    • 0142240338 scopus 로고    scopus 로고
    • Immune control of tuberculosis by IFN-γ-inducible LRG-47
    • DOI 10.1126/science.1088063
    • MacMicking, J. D., Taylor, G. A. & McKinney, J. D. Immune control of tuberculosis by IFN-γ-inducible LRG-47. Science 302, 654-659 (2003). (Pubitemid 37310923)
    • (2003) Science , vol.302 , Issue.5645 , pp. 654-659
    • MacMicking, J.D.1    Taylor, G.A.2    McKinney, J.D.3
  • 148
    • 0031010661 scopus 로고    scopus 로고
    • Identification of nitric oxide synthase as a protective locus against tuberculosis
    • MacMicking, J. D. et al. Identification of nitric oxide synthase as a protective locus against tuberculosis. Proc. Natl Acad. Sci. USA 94, 5243-5248 (1997).
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 5243-5248
    • MacMicking, J.D.1
  • 149
    • 80055109822 scopus 로고    scopus 로고
    • Regulation of neutrophils by interferon-γ limits lung inflammation during tuberculosis infection
    • Nandi, B. & Behar, S. M. Regulation of neutrophils by interferon-γ limits lung inflammation during tuberculosis infection. J. Exp. Med. 208, 2251-2262 (2011).
    • (2011) J. Exp. Med. , vol.208 , pp. 2251-2262
    • Nandi, B.1    Behar, S.M.2
  • 150
    • 59949094635 scopus 로고    scopus 로고
    • Anti-infectious activity of tryptophan metabolites in the l-tryptophan-l-kynurenine pathway
    • Narui, K. et al. Anti-infectious activity of tryptophan metabolites in the l-tryptophan-l-kynurenine pathway. Biol. Pharm. Bull. 32, 41-44 (2009).
    • (2009) Biol. Pharm. Bull. , vol.32 , pp. 41-44
    • Narui, K.1
  • 151
    • 34248173331 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase and tumor-induced tolerance
    • DOI 10.1172/JCI31178
    • Munn, D. H. & Mellor, A. L. Indoleamine 2,3-dioxygenase and tumor-induced tolerance. J. Clin. Invest. 117, 1147-1154 (2007). (Pubitemid 46718399)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.5 , pp. 1147-1154
    • Munn, D.H.1    Mellor, A.L.2
  • 152
    • 75149129648 scopus 로고    scopus 로고
    • A role for IL-18 in protective immunity against Mycobacterium tuberculosis
    • Schneider, B. E. et al. A role for IL-18 in protective immunity against Mycobacterium tuberculosis. Eur. J. Immunol. 40, 396-405 (2010).
    • (2010) Eur. J. Immunol. , vol.40 , pp. 396-405
    • Schneider, B.E.1
  • 153
    • 77955390095 scopus 로고    scopus 로고
    • Pathological role of interleukin 17 in mice subjected to repeated BCG vaccination after infection with Mycobacterium tuberculosis
    • Cruz, A. et al. Pathological role of interleukin 17 in mice subjected to repeated BCG vaccination after infection with Mycobacterium tuberculosis. J. Exp. Med. 207, 1609-1616 (2010).
    • (2010) J. Exp. Med. , vol.207 , pp. 1609-1616
    • Cruz, A.1
  • 154
    • 77951037591 scopus 로고    scopus 로고
    • The adaptor molecule CARD9 is essential for tuberculosis control
    • Dorhoi, A. et al. The adaptor molecule CARD9 is essential for tuberculosis control. J. Exp. Med. 207, 777-792 (2010).
    • (2010) J. Exp. Med. , vol.207 , pp. 777-792
    • Dorhoi, A.1
  • 155
    • 33845683474 scopus 로고    scopus 로고
    • Who puts the tubercle in tuberculosis?
    • DOI 10.1038/nrmicro1538, PII NRMICRO1538
    • Russell, D. G. Who puts the tubercle in tuberculosis? Nature Rev. Microbiol. 5, 39-47 (2007). (Pubitemid 44942302)
    • (2007) Nature Reviews Microbiology , vol.5 , Issue.1 , pp. 39-47
    • Russell, D.G.1
  • 156
    • 0031570939 scopus 로고    scopus 로고
    • IL-4 protects against TNF-α-mediated cachexia and death during acute schistosomiasis
    • Brunet, L. R., Finkelman, F. D., Cheever, A. W., Kopf, M. A. & Pearce, E. J. IL-4 protects against TNF-α-mediated cachexia and death during acute schistosomiasis. J. Immunol. 159, 777-785 (1997). (Pubitemid 127484229)
    • (1997) Journal of Immunology , vol.159 , Issue.2 , pp. 777-785
    • Brunet, L.R.1    Finkelman, F.D.2    Cheever, A.W.3    Kopf, M.A.4    Pearce, E.J.5
  • 157
    • 0033120068 scopus 로고    scopus 로고
    • Tolerization of mice to Schistosoma mansoni egg antigens causes elevated type 1 and diminished type 2 cytokine responses and increased mortality in acute infection
    • Fallon, P. G. & Dunne, D. W. Tolerization of mice to Schistosoma mansoni egg antigens causes elevated type 1 and diminished type 2 cytokine responses and increased mortality in acute infection. J. Immunol. 162, 4122-4132 (1999). (Pubitemid 29314797)
    • (1999) Journal of Immunology , vol.162 , Issue.7 , pp. 4122-4132
    • Fallon, P.G.1    Dunne, D.W.2
  • 158
    • 0033984466 scopus 로고    scopus 로고
    • Elevated type 1, diminished type 2 cytokines and impaired antibody response are associated with hepatotoxicity and mortalities during Schistosoma mansoni infection of CD4-depleted mice
    • DOI 10.1002/1521-4141(200002)30:2<470::AID-IMMU470>3.0.CO;2-T
    • Fallon, P. G., Richardson, E. J., Smith, P. & Dunne, D. W. Elevated type 1, diminished type 2 cytokines and impaired antibody response are associated with hepatotoxicity and mortalities during Schistosoma mansoni infection of CD4-depleted mice. Eur. J. Immunol. 30, 470-480 (2000). (Pubitemid 30098839)
    • (2000) European Journal of Immunology , vol.30 , Issue.2 , pp. 470-480
    • Fallon, P.G.1    Richardson, E.J.2    Smith, P.3    Dunne, D.W.4
  • 159
    • 0026554818 scopus 로고
    • Tumour necrosis factor α restores granulomas and induces parasite egg-laying in schistosome-infected SCID mice
    • Amiri, P. et al. Tumour necrosis factor α restores granulomas and induces parasite egg-laying in schistosome-infected SCID mice. Nature 356, 604-607 (1992).
    • (1992) Nature , vol.356 , pp. 604-607
    • Amiri, P.1
  • 161
    • 0036408395 scopus 로고    scopus 로고
    • Induced sputum-retrieved matrix metalloproteinase 9 and tissue metalloproteinase inhibitor 1 in granulomatous diseases
    • DOI 10.1046/j.1365-2249.2002.t01-1-02001.x
    • Fireman, E., Kraiem, Z., Sade, O., Greif, J. & Fireman, Z. Induced sputum-retrieved matrix metalloproteinase 9 and tissue metalloproteinase inhibitor 1 in granulomatous diseases. Clin. Exp. Immunol. 130, 331-337 (2002). (Pubitemid 35286223)
    • (2002) Clinical and Experimental Immunology , vol.130 , Issue.2 , pp. 331-337
    • Fireman, E.1    Kraiem, Z.2    Sade, O.3    Greif, J.4    Fireman, Z.5
  • 162
    • 80054013435 scopus 로고    scopus 로고
    • The selected genetic polymorphisms of metalloproteinases MMP2 7, 9 and MMP inhibitor TIMP2 in sarcoidosis
    • Piotrowski, W., Gσrski, P., Pietras, T., Fendler, W. & Szemraj, J. The selected genetic polymorphisms of metalloproteinases MMP2, 7, 9 and MMP inhibitor TIMP2 in sarcoidosis. Med. Sci. Monit. 10, CR598-CR607 (2011).
    • (2011) Med. Sci. Monit. , vol.10
    • Piotrowski, W.1    Gorski, P.2    Pietras, T.3    Fendler, W.4    Szemraj, J.5
  • 163
    • 0026632826 scopus 로고
    • Identification of the uncultured bacillus of Whipple's disease
    • Relman, D. A., Schmidt, T. M., MacDermott, R. P. & Falkow, S. Identification of the uncultured bacillus of Whipple's disease. N. Engl. J. Med. 327, 293-301 (1992).
    • (1992) N. Engl. J. Med. , vol.327 , pp. 293-301
    • Relman, D.A.1    Schmidt, T.M.2    MacDermott, R.P.3    Falkow, S.4
  • 166
    • 33646143975 scopus 로고    scopus 로고
    • Lessons from experimental Mycobacterium tuberculosis infections
    • Flynn, J. L. Lessons from experimental Mycobacterium tuberculosis infections. Microbes Infect. 8, 1179-1188 (2006).
    • (2006) Microbes Infect. , vol.8 , pp. 1179-1188
    • Flynn, J.L.1
  • 167
    • 67049142961 scopus 로고    scopus 로고
    • Dominant role of the sst1 locus in pathogenesis of necrotizing lung granulomas during chronic tuberculosis infection and reactivation in genetically resistant hosts
    • Pichugin, A. V., Yan, B. S., Sloutsky, A., Kobzik, L. & Kramnik, I. Dominant role of the sst1 locus in pathogenesis of necrotizing lung granulomas during chronic tuberculosis infection and reactivation in genetically resistant hosts. Am. J. Pathol. 174, 2190-2201 (2009).
    • (2009) Am. J. Pathol. , vol.174 , pp. 2190-2201
    • Pichugin, A.V.1    Yan, B.S.2    Sloutsky, A.3    Kobzik, L.4    Kramnik, I.5
  • 168
    • 42149094416 scopus 로고    scopus 로고
    • Comparative pathogenesis of Mycobacterium marinum and Mycobacterium tuberculosis
    • DOI 10.1111/j.1462-5822.2008.01133.x
    • Tobin, D. M. & Ramakrishnan, L. Comparative pathogenesis of Mycobacterium marinum and Mycobacterium tuberculosis. Cell. Microbiol. 10, 1027-1039 (2008). (Pubitemid 351540503)
    • (2008) Cellular Microbiology , vol.10 , Issue.5 , pp. 1027-1039
    • Tobin, D.M.1    Ramakrishnan, L.2
  • 169
    • 0034717008 scopus 로고    scopus 로고
    • Granuloma-specific expression of Mycobacterium virulence proteins from the glycine-rich PE-PGRS family
    • DOI 10.1126/science.288.5470.1436
    • Ramakrishnan, L., Federspiel, N. A. & Falkow, S. Granuloma-specific expression of Mycobacterium virulence proteins from the glycine-rich PE-PGRS family. Science 288, 1436-1439 (2000). (Pubitemid 30366332)
    • (2000) Science , vol.288 , Issue.5470 , pp. 1436-1439
    • Ramakrishnan, L.1    Federspiel, N.A.2    Falkow, S.3


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