-
1
-
-
34250684588
-
Spontaneous or Mycobacterium tuberculosis-induced apoptotic neutrophils exert opposite effects on the dendritic cell-mediated immune response
-
Alemán, M., de la Barrera, S., Schierloh, P., Yokobori, N., Baldini, M., Musella, R., Abbate, E. and Sasiain, M. (2007). Spontaneous or Mycobacterium tuberculosis-induced apoptotic neutrophils exert opposite effects on the dendritic cell-mediated immune response. Eur. J. Immunol. 37, 1524-1537.
-
(2007)
Eur. J. Immunol.
, vol.37
, pp. 1524-1537
-
-
Alemán, M.1
De La Barrera, S.2
Schierloh, P.3
Yokobori, N.4
Baldini, M.5
Musella, R.6
Abbate, E.7
Sasiain, M.8
-
2
-
-
70449705831
-
The spectrum of latent tuberculosis: Rethinking the biology and intervention strategies
-
Barry, C. E., III, Boshoff, H. I., Dartois, V., Dick, T., Ehrt, S., Flynn, J., Schnappinger, D., Wilkinson, R. J. and Young, D. (2009). The spectrum of latent tuberculosis: rethinking the biology and intervention strategies. Nat. Rev. Microbiol. 7, 845-855.
-
(2009)
Nat. Rev. Microbiol.
, vol.7
, pp. 845-855
-
-
Barry, C.E.1
Boshoff, H.I.2
Dartois, V.3
Dick, T.4
Ehrt, S.5
Flynn, J.6
Schnappinger, D.7
Wilkinson, R.J.8
Young, D.9
-
3
-
-
77955894773
-
An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis
-
Berry, M. P. R., Graham, C. M., McNab, F. W., Xu, Z., Bloch, S. A. A., Oni, T., Wilkinson, K. A., Banchereau, R., Skinner, J., Wilkinson, R. J. et al. (2010). An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis. Nature 466, 973-977.
-
(2010)
Nature
, vol.466
, pp. 973-977
-
-
Berry, M.P.R.1
Graham, C.M.2
McNab, F.W.3
Xu, Z.4
Bloch, S.A.A.5
Oni, T.6
Wilkinson, K.A.7
Banchereau, R.8
Skinner, J.9
Wilkinson, R.J.10
-
4
-
-
79959564980
-
Lung neutrophils facilitate activation of naive antigen-specific CD4+ T cells during Mycobacterium tuberculosis infection
-
Blomgran, R. and Ernst, J. D. (2011). Lung neutrophils facilitate activation of naive antigen-specific CD4+ T cells during Mycobacterium tuberculosis infection. J. Immunol. 186, 7110-7119.
-
(2011)
J. Immunol.
, vol.186
, pp. 7110-7119
-
-
Blomgran, R.1
Ernst, J.D.2
-
6
-
-
84862565266
-
Escape of Mycobacterium tuberculosis from oxidative killing by neutrophils
-
Corleis, B., Korbel, D., Wilson, R., Bylund, J., Chee, R. and Schaible, U. E. (2012). Escape of Mycobacterium tuberculosis from oxidative killing by neutrophils. Cell. Microbiol. 14, 1109-1121.
-
(2012)
Cell. Microbiol.
, vol.14
, pp. 1109-1121
-
-
Corleis, B.1
Korbel, D.2
Wilson, R.3
Bylund, J.4
Chee, R.5
Schaible, U.E.6
-
7
-
-
84894068321
-
The path of anti-tuberculosis drugs: From blood to lesions to mycobacterial cells
-
Dartois, V. (2014). The path of anti-tuberculosis drugs: from blood to lesions to mycobacterial cells. Nat. Rev. Microbiol. 12, 159-167.
-
(2014)
Nat. Rev. Microbiol.
, vol.12
, pp. 159-167
-
-
Dartois, V.1
-
8
-
-
84881367368
-
A medicinal chemists' guide to the unique difficulties of lead optimization for tuberculosis
-
Dartois, V. and Barry, C. E., III. (2013). A medicinal chemists' guide to the unique difficulties of lead optimization for tuberculosis. Bioorg. Med. Chem. Lett. 23, 4741-4750.
-
(2013)
Bioorg. Med. Chem. Lett.
, vol.23
, pp. 4741-4750
-
-
Dartois, V.1
Barry, C.E.2
-
9
-
-
58149083837
-
The role of the granuloma in expansion and dissemination of early tuberculous infection
-
Davis, J. M. and Ramakrishnan, L. (2009). The role of the granuloma in expansion and dissemination of early tuberculous infection. Cell 136, 37-49.
-
(2009)
Cell
, vol.136
, pp. 37-49
-
-
Davis, J.M.1
Ramakrishnan, L.2
-
10
-
-
84861163743
-
Evaluation of a mouse model of necrotic granuloma formation using C3HeB/FeJ mice for testing of drugs against Mycobacterium tuberculosis
-
Driver, E. R., Ryan, G. J., Hoff, D. R., Irwin, S. M., Basaraba, R. J., Kramnik, I. and Lenaerts, A. J. (2012). Evaluation of a mouse model of necrotic granuloma formation using C3HeB/FeJ mice for testing of drugs against Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 56, 3181-3195.
-
(2012)
Antimicrob. Agents Chemother.
, vol.56
, pp. 3181-3195
-
-
Driver, E.R.1
Ryan, G.J.2
Hoff, D.R.3
Irwin, S.M.4
Basaraba, R.J.5
Kramnik, I.6
Lenaerts, A.J.7
-
11
-
-
84903180280
-
Characterization of a novel necrotic granuloma model of latent tuberculosis infection and reactivation in mice
-
Dutta, N. K., Illei, P. B., Jain, S. K. and Karakousis, P. C. (2014). Characterization of a novel necrotic granuloma model of latent tuberculosis infection and reactivation in mice. Am. J. Pathol. 184, 2045-2055.
-
(2014)
Am. J. Pathol.
, vol.184
, pp. 2045-2055
-
-
Dutta, N.K.1
Illei, P.B.2
Jain, S.K.3
Karakousis, P.C.4
-
12
-
-
74949135138
-
Neutrophils are the predominant infected phagocytic cells in the airways of patients with active pulmonary TB
-
Eum, S.-Y., Kong, J.-H., Hong, M.-S., Lee, Y.-J., Kim, J.-H., Hwang, S.-H., Cho, S.-N., Via, L. E. and Barry, C. E., III. (2010). Neutrophils are the predominant infected phagocytic cells in the airways of patients with active pulmonary TB. Chest 137, 122-128.
-
(2010)
Chest
, vol.137
, pp. 122-128
-
-
Eum, S.-Y.1
Kong, J.-H.2
Hong, M.-S.3
Lee, Y.-J.4
Kim, J.-H.5
Hwang, S.-H.6
Cho, S.-N.7
Via, L.E.8
Barry, C.E.9
-
13
-
-
0037417012
-
Mycobacterium tuberculosis in the extracellular compartment: An underestimated adversary
-
Grosset, J. (2003). Mycobacterium tuberculosis in the extracellular compartment: an underestimated adversary. Antimicrob. Agents Chemother. 47, 833-836.
-
(2003)
Antimicrob. Agents Chemother.
, vol.47
, pp. 833-836
-
-
Grosset, J.1
-
14
-
-
84856301870
-
Mouse model of necrotic tuberculosis granulomas develops hypoxic lesions
-
Harper, J., Skerry, C., Davis, S. L., Tasneen, R., Weir, M., Kramnik, I., Bishai, W. R., Pomper, M. G., Nuermberger, E. L. and Jain, S. K. (2012). Mouse model of necrotic tuberculosis granulomas develops hypoxic lesions. J. Infect. Dis. 205, 595-602.
-
(2012)
J. Infect. Dis.
, vol.205
, pp. 595-602
-
-
Harper, J.1
Skerry, C.2
Davis, S.L.3
Tasneen, R.4
Weir, M.5
Kramnik, I.6
Bishai, W.R.7
Pomper, M.G.8
Nuermberger, E.L.9
Jain, S.K.10
-
15
-
-
79952847428
-
Location of intra- and extracellular M. tuberculosis populations in lungs of mice and guinea pigs during disease progression and after drug treatment
-
Hoff, D. R., Ryan, G. J., Driver, E. R., Ssemakulu, C. C., De Groote, M. A., Basaraba, R. J. and Lenaerts, A. J. (2011). Location of intra- and extracellular M. tuberculosis populations in lungs of mice and guinea pigs during disease progression and after drug treatment. PLoS ONE 6, e17550.
-
(2011)
PLoS ONE
, vol.6
-
-
Hoff, D.R.1
Ryan, G.J.2
Driver, E.R.3
Ssemakulu, C.C.4
De Groote, M.A.5
Basaraba, R.J.6
Lenaerts, A.J.7
-
16
-
-
84903188913
-
Limited activity of clofazimine as a single drug in a mouse model of tuberculosis exhibiting caseous necrotic granulomas
-
Irwin, S. M., Gruppo, V., Brooks, E., Gilliland, J., Scherman, M., Reichlen, M. J., Leistikow, R., Kramnik, I., Nuermberger, E. L., Voskuil, M. I. et al. (2014). Limited activity of clofazimine as a single drug in a mouse model of tuberculosis exhibiting caseous necrotic granulomas. Antimicrob. Agents Chemother. 58, 4026-4034.
-
(2014)
Antimicrob. Agents Chemother.
, vol.58
, pp. 4026-4034
-
-
Irwin, S.M.1
Gruppo, V.2
Brooks, E.3
Gilliland, J.4
Scherman, M.5
Reichlen, M.J.6
Leistikow, R.7
Kramnik, I.8
Nuermberger, E.L.9
Voskuil, M.I.10
-
17
-
-
0029829728
-
Low-dose aerosol infection model for testing drugs for efficacy against Mycobacterium tuberculosis
-
Kelly, B. P., Furney, S. K., Jessen, M. T. and Orme, I. M. (1996). Low-dose aerosol infection model for testing drugs for efficacy against Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 40, 2809-2812.
-
(1996)
Antimicrob. Agents Chemother.
, vol.40
, pp. 2809-2812
-
-
Kelly, B.P.1
Furney, S.K.2
Jessen, M.T.3
Orme, I.M.4
-
19
-
-
84930579682
-
Heterogeneous disease progression and treatment response in a C3HeB/FeJ mouse model of tuberculosis
-
Lanoix, J.-P., Lenaerts, A. J. and Nuermberger, E. L. (2015). Heterogeneous disease progression and treatment response in a C3HeB/FeJ mouse model of tuberculosis. Dis. Model. Mech. 8, 603-610.
-
(2015)
Dis. Model. Mech.
, vol.8
, pp. 603-610
-
-
Lanoix, J.-P.1
Lenaerts, A.J.2
Nuermberger, E.L.3
-
20
-
-
7544238351
-
Statistical limitations to the Cornell model of latent tuberculosis infection for the study of relapse rates
-
Lenaerts, A. J., Chapman, P. L. and Orme, I. M. (2004). Statistical limitations to the Cornell model of latent tuberculosis infection for the study of relapse rates. Tuberculosis (Edinb.) 84, 361-364.
-
(2004)
Tuberculosis (Edinb.)
, vol.84
, pp. 361-364
-
-
Lenaerts, A.J.1
Chapman, P.L.2
Orme, I.M.3
-
21
-
-
19544364888
-
Preclinical testing of the nitroimidazopyran PA-824 for activity against Mycobacterium tuberculosis in a series of in vitro and in vivo models
-
Lenaerts, A. J., Gruppo, V., Marietta, K. S., Johnson, C. M., Driscoll, D. K., Tompkins, N. M., Rose, J. D., Reynolds, R. C. and Orme, I. M. (2005). Preclinical testing of the nitroimidazopyran PA-824 for activity against Mycobacterium tuberculosis in a series of in vitro and in vivo models. Antimicrob. Agents Chemother. 49, 2294-2301.
-
(2005)
Antimicrob. Agents Chemother.
, vol.49
, pp. 2294-2301
-
-
Lenaerts, A.J.1
Gruppo, V.2
Marietta, K.S.3
Johnson, C.M.4
Driscoll, D.K.5
Tompkins, N.M.6
Rose, J.D.7
Reynolds, R.C.8
Orme, I.M.9
-
22
-
-
77956216718
-
Understanding latent tuberculosis: A moving target
-
Lin, P. L. and Flynn, J. L. (2010). Understanding latent tuberculosis: a moving target. J. Immunol. 185, 15-22.
-
(2010)
J. Immunol.
, vol.185
, pp. 15-22
-
-
Lin, P.L.1
Flynn, J.L.2
-
23
-
-
70349427123
-
Quantitative comparison of active and latent tuberculosis in the cynomolgus macaque model
-
Lin, P. L., Rodgers, M., Smith, L., Bigbee, M., Myers, A., Bigbee, C., Chiosea, I., Capuano, S. V., Fuhrman, C., Klein, E. et al. (2009). Quantitative comparison of active and latent tuberculosis in the cynomolgus macaque model. Infect. Immun. 77, 4631-4642.
-
(2009)
Infect. Immun.
, vol.77
, pp. 4631-4642
-
-
Lin, P.L.1
Rodgers, M.2
Smith, L.3
Bigbee, M.4
Myers, A.5
Bigbee, C.6
Chiosea, I.7
Capuano, S.V.8
Fuhrman, C.9
Klein, E.10
-
24
-
-
84882427707
-
Radiologic responses in cynomolgus macaques for assessing tuberculosis chemotherapy regimens
-
Lin, P. L., Coleman, T., Carney, J. P. J, Lopresti, B. J., Tomko, J., Fillmore, D., Dartois, V., Scanga, C., Frye, L. J., Janssen, C. et al. (2013). Radiologic responses in cynomolgus macaques for assessing tuberculosis chemotherapy regimens. Antimicrob. Agents Chemother. 57, 4237-4244.
-
(2013)
Antimicrob. Agents Chemother.
, vol.57
, pp. 4237-4244
-
-
Lin, P.L.1
Coleman, T.2
Carney, J.P.J.3
Lopresti, B.J.4
Tomko, J.5
Fillmore, D.6
Dartois, V.7
Scanga, C.8
Frye, L.J.9
Janssen, C.10
-
25
-
-
84891853921
-
Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing
-
Lin, P. L., Ford, C. B., Coleman, M. T., Myers, A. J., Gawande, R., Ioerger, T., Sacchettini, J., Fortune, S. M. and Flynn, J. L. (2014). Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing. Nat. Med. 20, 75-79.
-
(2014)
Nat. Med.
, vol.20
, pp. 75-79
-
-
Lin, P.L.1
Ford, C.B.2
Coleman, M.T.3
Myers, A.J.4
Gawande, R.5
Ioerger, T.6
Sacchettini, J.7
Fortune, S.M.8
Flynn, J.L.9
-
26
-
-
84887546962
-
Tuberculosis in CBA/J mice
-
Major, S., Turner, J. and Beamer, G. (2013). Tuberculosis in CBA/J mice. Vet. Pathol. 50, 1016-1021.
-
(2013)
Vet. Pathol.
, vol.50
, pp. 1016-1021
-
-
Major, S.1
Turner, J.2
Beamer, G.3
-
27
-
-
43049159478
-
The aerosol rabbit model of TB latency, reactivation and immune reconstitution inflammatory syndrome
-
Manabe, Y. C., Kesavan, A. K., Lopez-Molina, J., Hatem, C. L., Brooks, M., Fujiwara, R., Hochstein, K., Pitt, M. L. M., Tufariello, J., Chan, J. et al. (2008). The aerosol rabbit model of TB latency, reactivation and immune reconstitution inflammatory syndrome. Tuberculosis (Edinb.) 88, 187-196.
-
(2008)
Tuberculosis (Edinb.)
, vol.88
, pp. 187-196
-
-
Manabe, Y.C.1
Kesavan, A.K.2
Lopez-Molina, J.3
Hatem, C.L.4
Brooks, M.5
Fujiwara, R.6
Hochstein, K.7
Pitt, M.L.M.8
Tufariello, J.9
Chan, J.10
-
28
-
-
84891555267
-
Damaging role of neutrophilic infiltration in a mouse model of progressive tuberculosis
-
Marzo, E., Vilaplana, C., Tapia, G., Diaz, J., Garcia, V. and Cardona, P.-J. (2014). Damaging role of neutrophilic infiltration in a mouse model of progressive tuberculosis. Tuberculosis (Edinb.) 94, 55-64.
-
(2014)
Tuberculosis (Edinb.)
, vol.94
, pp. 55-64
-
-
Marzo, E.1
Vilaplana, C.2
Tapia, G.3
Diaz, J.4
Garcia, V.5
Cardona, P.-J.6
-
29
-
-
0033958803
-
Neutrophils play a protective nonphagocytic role in systemic Mycobacterium tuberculosis infection of mice
-
Pedrosa, J., Saunders, B. M., Appelberg, R., Orme, I. M., Silva, M. T. and Cooper, A. M. (2000). Neutrophils play a protective nonphagocytic role in systemic Mycobacterium tuberculosis infection of mice. Infect. Immun. 68, 577-583.
-
(2000)
Infect. Immun.
, vol.68
, pp. 577-583
-
-
Pedrosa, J.1
Saunders, B.M.2
Appelberg, R.3
Orme, I.M.4
Silva, M.T.5
Cooper, A.M.6
-
30
-
-
67049142961
-
Dominant role of the sst1 locus in pathogenesis of necrotizing lung granulomas during chronic tuberculosis infection and reactivation in genetically resistant hosts
-
Pichugin, A. V., Yan, B.-S., Sloutsky, A., Kobzik, L. and Kramnik, I. (2009). Dominant role of the sst1 locus in pathogenesis of necrotizing lung granulomas during chronic tuberculosis infection and reactivation in genetically resistant hosts. Am. J. Pathol. 174, 2190-2201.
-
(2009)
Am. J. Pathol.
, vol.174
, pp. 2190-2201
-
-
Pichugin, A.V.1
Yan, B.-S.2
Sloutsky, A.3
Kobzik, L.4
Kramnik, I.5
-
31
-
-
79954595692
-
High-sensitivity MALDI-MRM-MS imaging of moxifloxacin distribution in tuberculosis-infected rabbit lungs and granulomatous lesions
-
Prideaux, B., Dartois, V., Staab, D., Weiner, D. M., Goh, A., Via, L. E., Barry, C. E., III and Stoeckli, M. (2011). High-sensitivity MALDI-MRM-MS imaging of moxifloxacin distribution in tuberculosis-infected rabbit lungs and granulomatous lesions. Anal. Chem. 83, 2112-2118.
-
(2011)
Anal. Chem.
, vol.83
, pp. 2112-2118
-
-
Prideaux, B.1
Dartois, V.2
Staab, D.3
Weiner, D.M.4
Goh, A.5
Via, L.E.6
Barry, C.E.7
Stoeckli, M.8
-
32
-
-
84884818287
-
Early lesions following aerosol infection of rhesus macaques (Macaca mulatta) with Mycobacterium tuberculosis strain H37RV
-
Rayner, E. L., Pearson, G. R., Hall, G. A., Basaraba, R. J., Gleeson, F., McIntyre, A., Clark, S., Williams, A., Dennis, M. J. and Sharpe, S. A. (2013). Early lesions following aerosol infection of rhesus macaques (Macaca mulatta) with Mycobacterium tuberculosis strain H37RV. J. Comp. Pathol. 149, 475-485.
-
(2013)
J. Comp. Pathol.
, vol.149
, pp. 475-485
-
-
Rayner, E.L.1
Pearson, G.R.2
Hall, G.A.3
Basaraba, R.J.4
Gleeson, F.5
McIntyre, A.6
Clark, S.7
Williams, A.8
Dennis, M.J.9
Sharpe, S.A.10
-
33
-
-
0031442875
-
Progression of chronic pulmonary tuberculosis in mice aerogenically infected with virulent Mycobacterium tuberculosis
-
Rhoades, E. R., Frank, A. A. and Orme, I. M. (1997). Progression of chronic pulmonary tuberculosis in mice aerogenically infected with virulent Mycobacterium tuberculosis. Tuber. Lung Dis. 78, 57-66.
-
(1997)
Tuber. Lung Dis.
, vol.78
, pp. 57-66
-
-
Rhoades, E.R.1
Frank, A.A.2
Orme, I.M.3
-
34
-
-
84908138044
-
Improving acid-fast fluorescent staining for the detection of mycobacteria using a new nucleic acid staining approach
-
Ryan, G. J., Shapiro, H. M. and Lenaerts, A. J. (2014). Improving acid-fast fluorescent staining for the detection of mycobacteria using a new nucleic acid staining approach. Tuberculosis (Edinb.) 94, 511-518.
-
(2014)
Tuberculosis (Edinb.)
, vol.94
, pp. 511-518
-
-
Ryan, G.J.1
Shapiro, H.M.2
Lenaerts, A.J.3
-
35
-
-
0034090797
-
Rapid neutrophil response controls fast-replicating intracellular bacteria but not slow-replicating Mycobacterium tuberculosis
-
Seiler, P., Aichele, P., Raupach, B., Odermatt, B., Steinhoff, U. and Kaufmann, S. H. E. (2000). Rapid neutrophil response controls fast-replicating intracellular bacteria but not slow-replicating Mycobacterium tuberculosis. J. Infect. Dis. 181, 671-680.
-
(2000)
J. Infect. Dis.
, vol.181
, pp. 671-680
-
-
Seiler, P.1
Aichele, P.2
Raupach, B.3
Odermatt, B.4
Steinhoff, U.5
Kaufmann, S.H.E.6
-
36
-
-
84882470985
-
Early innate immunity determines outcome of Mycobacterium tuberculosis pulmonary infection in rabbits
-
Subbian, S., Bandyopadhyay, N., Tsenova, L., O'Brien, P., Khetani, V., Kushner, N. L., Peixoto, B., Soteropoulos, P., Bader, J. S., Karakousis, P. C. et al. (2013). Early innate immunity determines outcome of Mycobacterium tuberculosis pulmonary infection in rabbits. Cell Commun. Signal. 11, 60.
-
(2013)
Cell Commun. Signal.
, vol.11
, pp. 60
-
-
Subbian, S.1
Bandyopadhyay, N.2
Tsenova, L.3
O'Brien, P.4
Khetani, V.5
Kushner, N.L.6
Peixoto, B.7
Soteropoulos, P.8
Bader, J.S.9
Karakousis, P.C.10
-
37
-
-
0037304668
-
Immunopathogenesis of pulmonary granulomas in the guinea pig after infection with Mycobacterium tuberculosis
-
Turner, O. C., Basaraba, R. J. and Orme, I. M. (2003). Immunopathogenesis of pulmonary granulomas in the guinea pig after infection with Mycobacterium tuberculosis. Infect. Immun. 71, 864-871.
-
(2003)
Infect. Immun.
, vol.71
, pp. 864-871
-
-
Turner, O.C.1
Basaraba, R.J.2
Orme, I.M.3
-
38
-
-
0029976980
-
An in vitro model for sequential study of shiftdown of Mycobacterium tuberculosis through two stages of nonreplicating persistence
-
Wayne, L. G. and Hayes, L. G. (1996). An in vitro model for sequential study of shiftdown of Mycobacterium tuberculosis through two stages of nonreplicating persistence. Infect. Immun. 64, 2062-2069.
-
(1996)
Infect. Immun.
, vol.64
, pp. 2062-2069
-
-
Wayne, L.G.1
Hayes, L.G.2
|