-
1
-
-
84956762643
-
The linear arrangement of six sex-linked factors in Drosophila, as shown by their mode of association
-
Sturtevant, A. J. The linear arrangement of six sex-linked factors in Drosophila, as shown by their mode of association. J. Exp. Zool. 14, 59 (1913).
-
(1913)
J. Exp. Zool
, vol.14
, pp. 59
-
-
Sturtevant, A.J.1
-
2
-
-
41749088902
-
The HLA rgion and autoimmune disease: Associations and mechanisms of action
-
Gough, S. C. & Simmonds, M. J. The HLA rgion and autoimmune disease: associations and mechanisms of action. Curr. Genom. 8, 453-465 (2007).
-
(2007)
Curr. Genom
, vol.8
, pp. 453-465
-
-
Gough, S.C.1
Simmonds, M.J.2
-
3
-
-
0037648405
-
Association of the T cell regulatory gene CTLA4 with susceptibility to autoimmune disease
-
Ueda, H., et al. Association of the T cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 423, 506-511 (2003).
-
(2003)
Nature
, vol.423
, pp. 506-511
-
-
Ueda, H.1
-
4
-
-
20144387851
-
Analysis of families in the multiple autoimmune disease genetics consortium (MADGC) collection: The PTPN22 620W allele associates with multiple autoimmune phenotypes
-
Criswell, L. A., et al. Analysis of families in the multiple autoimmune disease genetics consortium (MADGC) collection: the PTPN22 620W allele associates with multiple autoimmune phenotypes. Am. J. Hum. Genet. 76, 561-571 (2005).
-
(2005)
Am. J. Hum. Genet
, vol.76
, pp. 561-571
-
-
Criswell, L.A.1
-
5
-
-
57749193136
-
Detecting shared pathogenesis from the shared genetics of immune-related diseases
-
Zhernakova, A., Van Diemen, C. C. & Wijmenga, C. Detecting shared pathogenesis from the shared genetics of immune-related diseases. Nat. Rev. Genet. 10, 43-55 (2009).
-
(2009)
Nat. Rev. Genet
, vol.10
, pp. 43-55
-
-
Zhernakova, A.1
Van Diemen, C.C.2
Wijmenga, C.3
-
6
-
-
34249888775
-
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
-
Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, Lund University, and Novartis Institutes of BioMedical Research et al.
-
Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, Lund University, and Novartis Institutes of BioMedical Research et al. Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 316, 1331-1336 (2007).
-
(2007)
Science
, vol.316
, pp. 1331-1336
-
-
-
7
-
-
34249996115
-
A common allele on chromosome 9 associated with coronary heart disease
-
McPherson, R., et al. A common allele on chromosome 9 associated with coronary heart disease. Science 316, 1488-1491 (2007).
-
(2007)
Science
, vol.316
, pp. 1488-1491
-
-
McPherson, R.1
-
8
-
-
34250010480
-
A common variant on chromosome 9p21 affects the risk of myocardial infarction
-
Helgadottir, A., et al. A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science 316, 1491-1493 (2007).
-
(2007)
Science
, vol.316
, pp. 1491-1493
-
-
Helgadottir, A.1
-
9
-
-
34547623750
-
Genomewide association analysis of coronary artery disease
-
Samani, N. J., et al. Genomewide association analysis of coronary artery disease. N. Engl. J. Med. 357, 443-453 (2007).
-
(2007)
N. Engl. J. Med
, vol.357
, pp. 443-453
-
-
Samani, N.J.1
-
10
-
-
67249117049
-
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
-
Hindorff, L. A., et al. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc. Natl Acad. Sci. USA 106, 9362-9367 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 9362-9367
-
-
Hindorff, L.A.1
-
11
-
-
80955135827
-
Abundant pleiotropy in human complex diseases and traits
-
Sivakumaran, S., et al. Abundant pleiotropy in human complex diseases and traits. Am. J. Hum. Genet. 89, 607-618 (2011).
-
(2011)
Am. J. Hum. Genet
, vol.89
, pp. 607-618
-
-
Sivakumaran, S.1
-
12
-
-
84879419343
-
Pleiotropy in complex traits: Challenges and strategies
-
Solovieff, N., Cotsapas, C., Lee, P. H., Purcell, S. M. & Smoller, J. W. Pleiotropy in complex traits: challenges and strategies. Nat. Rev. Genet. 14, 483-495 (2013).
-
(2013)
Nat. Rev. Genet
, vol.14
, pp. 483-495
-
-
Solovieff, N.1
Cotsapas, C.2
Lee, P.H.3
Purcell, S.M.4
Smoller, J.W.5
-
13
-
-
78951491095
-
One hundred years of pleiotropy: A retrospective
-
Stearns, F. W. One hundred years of pleiotropy: a retrospective. Genetics 186, 767-773 (2010).
-
(2010)
Genetics
, vol.186
, pp. 767-773
-
-
Stearns, F.W.1
-
14
-
-
79951799418
-
The pleiotropic structure of the genotype-phenotype map: The evolvability of complex organisms
-
Wagner, G. P. & Zhang, J. The pleiotropic structure of the genotype-phenotype map: the evolvability of complex organisms. Nat. Rev. Genet. 12, 204-213 (2011).
-
(2011)
Nat. Rev. Genet
, vol.12
, pp. 204-213
-
-
Wagner, G.P.1
Zhang, J.2
-
15
-
-
84958599838
-
The detection and characterization of pleiotropy discovery, progress, and promise
-
Tyler, A. L., Crawford, D. C. & Pendergrass, S. A. The detection and characterization of pleiotropy. discovery, progress, and promise. Brief. Bioinform. 17, 13-22 (2016).
-
(2016)
Brief. Bioinform
, vol.17
, pp. 13-22
-
-
Tyler, A.L.1
Crawford, D.C.2
Pendergrass, S.A.3
-
16
-
-
84926659527
-
Opportunities for drug repositioning from phenome-wide association studies
-
Rastegar-Mojarad, M., Ye, Z., Kolesar, J. M., Hebbring, S. J. & Lin, S. M. Opportunities for drug repositioning from phenome-wide association studies. Nat. Biotechnol. 33, 342-345 (2015).
-
(2015)
Nat. Biotechnol
, vol.33
, pp. 342-345
-
-
Rastegar-Mojarad, M.1
Ye, Z.2
Kolesar, J.M.3
Hebbring, S.J.4
Lin, S.M.5
-
17
-
-
84923762812
-
New initiative on precision medicine
-
Collins, F. S. & Varmus, H. A. New initiative on precision medicine. N. Engl. J. Med. 372, 793-795 (2015).
-
(2015)
N. Engl. J. Med
, vol.372
, pp. 793-795
-
-
Collins, F.S.1
Varmus, H.A.2
-
18
-
-
84947094451
-
Phenome-wide association studies: Leveraging comprehensive phenotypic and genotypic data for discovery
-
Pendergrass, S. A. & Ritchie, M. Phenome-wide association studies: leveraging comprehensive phenotypic and genotypic data for discovery. Curr. Genet. Med. Rep. 3, 92-100 (2015).
-
(2015)
Curr. Genet. Med. Rep
, vol.3
, pp. 92-100
-
-
Pendergrass, S.A.1
Ritchie, M.2
-
19
-
-
84891895694
-
The challenges, advantages and future of phenome-wide association studies
-
Hebbring, S. J. The challenges, advantages and future of phenome-wide association studies. Immunology 141, 157-165 (2014).
-
(2014)
Immunology
, vol.141
, pp. 157-165
-
-
Hebbring, S.J.1
-
20
-
-
84937871974
-
Phenome-wide association studies: Embracing complexity for discovery
-
Pendergrass, S. A., et al. Phenome-wide association studies: embracing complexity for discovery. Hum. Hered. 3-4, 111-123 (2015).
-
(2015)
Hum. Hered
, vol.3-4
, pp. 111-123
-
-
Pendergrass, S.A.1
-
21
-
-
84860596557
-
Patterns of cis regulatory variation in diverse human populations
-
Stranger, B. E., et al. Patterns of cis regulatory variation in diverse human populations. PLoS Genet. 8, e1002639 (2012).
-
(2012)
PLoS Genet
, vol.8
, pp. e1002639
-
-
Stranger, B.E.1
-
22
-
-
55449112450
-
High-resolution mapping of expression-QTLs yields insight into human gene regulation
-
Veyrieras, J. B., et al. High-resolution mapping of expression-QTLs yields insight into human gene regulation. PLoS Genet. 4, e1000214 (2008).
-
(2008)
PLoS Genet
, vol.4
, pp. e1000214
-
-
Veyrieras, J.B.1
-
23
-
-
84868154284
-
The contribution of RNA decay quantitative trait loci to inter-individual variation in steady-state gene expression levels
-
Pai, A. A., et al. The contribution of RNA decay quantitative trait loci to inter-individual variation in steady-state gene expression levels. PLoS Genet. 8, e1003000 (2012).
-
(2012)
PLoS Genet
, vol.8
, pp. e1003000
-
-
Pai, A.A.1
-
24
-
-
84870674869
-
Controls of nucleosome positioning in the human genome
-
Gaffney, D. J., et al. Controls of nucleosome positioning in the human genome. PLoS Genet. 8, e1003036 (2012).
-
(2012)
PLoS Genet
, vol.8
, pp. e1003036
-
-
Gaffney, D.J.1
-
25
-
-
84857111200
-
DNase i sensitivity QTLs are a major determinant of human expression variation
-
Degner, J. F., et al. DNase I sensitivity QTLs are a major determinant of human expression variation. Nature 482, 390-394 (2012).
-
(2012)
Nature
, vol.482
, pp. 390-394
-
-
Degner, J.F.1
-
26
-
-
84922469439
-
Impact of regulatory variation from RNA to protein
-
Battle, A., et al. Impact of regulatory variation from RNA to protein. Science 347, 664-667 (2015).
-
(2015)
Science
, vol.347
, pp. 664-667
-
-
Battle, A.1
-
27
-
-
84879879014
-
Variation and genetic control of protein abundance in humans
-
Wu, L., et al. Variation and genetic control of protein abundance in humans. Nature 499, 79-82 (2013).
-
(2013)
Nature
, vol.499
, pp. 79-82
-
-
Wu, L.1
-
28
-
-
84905912559
-
Identification and validation of genetic variants that influence transcription factor and cell signaling protein levels
-
Hause, R., et al. Identification and validation of genetic variants that influence transcription factor and cell signaling protein levels. Am. J. Hum. Genet. 95, 194-208 (2014).
-
(2014)
Am. J. Hum. Genet
, vol.95
, pp. 194-208
-
-
Hause, R.1
-
29
-
-
77951439152
-
Trait-associated SNPs are more likely to be eQTLs: Annotation to enhance discovery from GWAS
-
Nicolae, D. L., et al. Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS. PLoS Genet. 6, e1000888 (2010).
-
(2010)
PLoS Genet
, vol.6
, pp. e1000888
-
-
Nicolae, D.L.1
-
30
-
-
60349092402
-
Mapping complex disease traits with global gene expression
-
Cookson, W., Liang, L., Abecasis, G., Moffatt, M. & Lathrop, M. Mapping complex disease traits with global gene expression. Nat. Rev. Genet. 10, 184-194 (2009).
-
(2009)
Nat. Rev. Genet
, vol.10
, pp. 184-194
-
-
Cookson, W.1
Liang, L.2
Abecasis, G.3
Moffatt, M.4
Lathrop, M.5
-
31
-
-
0035895505
-
The sequence of the human genome
-
Venter, J. C., et al. The sequence of the human genome. Science 291, 1304-1351 (2001).
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
-
32
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
Lander, E. S., et al. Initial sequencing and analysis of the human genome. Nature 409, 860-921 (2001).
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
Lander, E.S.1
-
33
-
-
79951481957
-
Initial impact of the sequencing of the human genome
-
Lander, E. S. Initial impact of the sequencing of the human genome. Nature 470, 187-197 (2011).
-
(2011)
Nature
, vol.470
, pp. 187-197
-
-
Lander, E.S.1
-
34
-
-
84872040426
-
Chapter 11: Genome-wide association studies
-
Bush, W. S. & Moore, J. H. Chapter 11: genome-wide association studies. PLoS Comput. Biol. 8, e1002822 (2012).
-
(2012)
PLoS Comput. Biol
, vol.8
, pp. e1002822
-
-
Bush, W.S.1
Moore, J.H.2
-
35
-
-
77952720637
-
Genome-wide association studies and beyond
-
Witte, J. S. Genome-wide association studies and beyond. Annu. Rev. Publ. Health 31, 9-20 (2010).
-
(2010)
Annu. Rev. Publ. Health
, vol.31
, pp. 9-20
-
-
Witte, J.S.1
-
36
-
-
55449120805
-
Genetic mapping in human disease
-
Altshuler, D., Daly, M. J. & Lander, E. S. Genetic mapping in human disease. Science 322, 881-888 (2008).
-
(2008)
Science
, vol.322
, pp. 881-888
-
-
Altshuler, D.1
Daly, M.J.2
Lander, E.S.3
-
37
-
-
84891790401
-
The NHGRI GWAS Catalog, a curated resource of SNP-trait associations
-
Welter, D., et al. The NHGRI GWAS Catalog, a curated resource of SNP-trait associations. Nucleic Acids Res. 42, D1001-D1006 (2014).
-
(2014)
Nucleic Acids Res
, vol.42
, pp. D1001-D1006
-
-
Welter, D.1
-
38
-
-
84861235431
-
Mining electronic health records: Towards better research applications and clinical care
-
Jensen, P. B., Jensen, L. J. & Brunak, S. Mining electronic health records: towards better research applications and clinical care. Nat. Rev. Genet. 13, 395-405 (2012).
-
(2012)
Nat. Rev. Genet
, vol.13
, pp. 395-405
-
-
Jensen, P.B.1
Jensen, L.J.2
Brunak, S.3
-
39
-
-
79956327715
-
Using electronic health records to drive discovery in disease genomics
-
Kohane, I. S. Using electronic health records to drive discovery in disease genomics. Nat. Rev. Genet. 12, 417-428 (2011).
-
(2011)
Nat. Rev. Genet
, vol.12
, pp. 417-428
-
-
Kohane, I.S.1
-
40
-
-
84939422197
-
Characterizing race/ethnicity and genetic ancestry for 100, 000 subjects in the genetic epidemiology research on adult health and aging (GERA) cohort
-
Banda, Y., et al. Characterizing race/ethnicity and genetic ancestry for 100, 000 subjects in the genetic epidemiology research on adult health and aging (GERA) cohort. Genetics 200, 1285-1295 (2015).
-
(2015)
Genetics
, vol.200
, pp. 1285-1295
-
-
Banda, Y.1
-
41
-
-
84939426058
-
Genotyping informatics and quality control for 100, 000 subjects in the genetic epidemiology research on adult health and aging (GERA) cohort
-
Kvale, M. N., et al. Genotyping informatics and quality control for 100, 000 subjects in the genetic epidemiology research on adult health and aging (GERA) cohort. Genetics 200, 1051-1060 (2015).
-
(2015)
Genetics
, vol.200
, pp. 1051-1060
-
-
Kvale, M.N.1
-
42
-
-
84957436835
-
Million Veteran Program: A mega-biobank to study genetic influences on health and disease
-
Gaziano, J. M., et al. Million Veteran Program: a mega-biobank to study genetic influences on health and disease. J. Clin. Epidemiol. 70, 214-223 (2016).
-
(2016)
J. Clin. Epidemiol
, vol.70
, pp. 214-223
-
-
Gaziano, J.M.1
-
43
-
-
79251581866
-
The eMERGE Network: A consortium of biorepositories linked to electronic medical records data for conducting genomic studies
-
McCarty, C., et al. The eMERGE Network: a consortium of biorepositories linked to electronic medical records data for conducting genomic studies. BMC Medical Genomics 4, 13 (2011).
-
(2011)
BMC Medical Genomics
, vol.4
, pp. 13
-
-
McCarty, C.1
-
44
-
-
84875931887
-
Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk
-
Ritchie, M. D., et al. Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk. Circulation 127, 1377-1385 (2013).
-
(2013)
Circulation
, vol.127
, pp. 1377-1385
-
-
Ritchie, M.D.1
-
45
-
-
78549244038
-
Identification of genomic predictors of atrioventricular conduction
-
Denny, J. C., et al. Identification of genomic predictors of atrioventricular conduction. Circulation 122, 2016-2021 (2010).
-
(2010)
Circulation
, vol.122
, pp. 2016-2021
-
-
Denny, J.C.1
-
46
-
-
84908666048
-
Electronic medical records and genomics (eMERGE) network exploration in cataract: Several new potential susceptbility loci
-
Ritchie, M. D., et al. Electronic medical records and genomics (eMERGE) network exploration in cataract: several new potential susceptbility loci. Mol. Vis. 20, 1281-1295 (2014).
-
(2014)
Mol. Vis
, vol.20
, pp. 1281-1295
-
-
Ritchie, M.D.1
-
47
-
-
84878832780
-
Enhancing the power of genetic association studies through the use of silver standard cases derived from electronic medical records
-
McDavid, A., et al. Enhancing the power of genetic association studies through the use of silver standard cases derived from electronic medical records. PLoS ONE 8, e63481 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e63481
-
-
McDavid, A.1
-
48
-
-
79955925612
-
Knowledge-driven multi-locus analysis reveals gene-gene interactions influencing HDL cholesterol level in two independent EMR-linked biobanks
-
Turner, S. D., et al. Knowledge-driven multi-locus analysis reveals gene-gene interactions influencing HDL cholesterol level in two independent EMR-linked biobanks. PLoS ONE 6, e19586 (2011).
-
(2011)
PLoS ONE
, vol.6
, pp. e19586
-
-
Turner, S.D.1
-
49
-
-
77958597919
-
Leveraging informatics for genetic studies: Use of the electronic medical record to enable a genome-wide association study of peripheral arterial disease
-
Kullo, I. J., et al. Leveraging informatics for genetic studies: use of the electronic medical record to enable a genome-wide association study of peripheral arterial disease. J. Am. Med. Inform. Assoc. 17, 568-574 (2010).
-
(2010)
J. Am. Med. Inform. Assoc
, vol.17
, pp. 568-574
-
-
Kullo, I.J.1
-
50
-
-
84857146745
-
Use of diverse electronic medical record systems to identify genetic risk for type 2 diabetes within a genome-wide association study
-
Kho, A. N., et al. Use of diverse electronic medical record systems to identify genetic risk for type 2 diabetes within a genome-wide association study. J. Am. Med. Inform. Assoc. 19, 212-218 (2012).
-
(2012)
J. Am. Med. Inform. Assoc
, vol.19
, pp. 212-218
-
-
Kho, A.N.1
-
51
-
-
79952103287
-
Gene-environment interactions in human disease: Nuisance or opportunity?
-
Ober, C. & Vercelli, D. Gene-environment interactions in human disease: nuisance or opportunity?. Trends Genet. 27, 107-115 (2011).
-
(2011)
Trends Genet
, vol.27
, pp. 107-115
-
-
Ober, C.1
Vercelli, D.2
-
52
-
-
21244440962
-
The search for genenotype/phenotype associations and the phenome scan
-
Jones, R., Pembrey, M., Golding, J. & Herrick, D. The search for genenotype/phenotype associations and the phenome scan. Paediatr. Perinatal Epidemiol. 19, 264-275 (2005).
-
(2005)
Paediatr. Perinatal Epidemiol
, vol.19
, pp. 264-275
-
-
Jones, R.1
Pembrey, M.2
Golding, J.3
Herrick, D.4
-
53
-
-
0038670579
-
The human phenome project
-
Freimer, N. & Sabatti, C. The human phenome project. Nat. Genet. 34, 15-21 (2003).
-
(2003)
Nat. Genet
, vol.34
, pp. 15-21
-
-
Freimer, N.1
Sabatti, C.2
-
54
-
-
77952822074
-
PheWAS: Demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations
-
Denny, J. C., et al. PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations. Bioinformatics 26, 1205-1210 (2010).
-
(2010)
Bioinformatics
, vol.26
, pp. 1205-1210
-
-
Denny, J.C.1
-
55
-
-
34548299105
-
Risk alleles for multiple sclerosis identified by a genomewide study
-
International Multiple Sclerosis Genetics Consortium et al.
-
International Multiple Sclerosis Genetics Consortium et al. Risk alleles for multiple sclerosis identified by a genomewide study. N. Engl. J. Med. 357, 851-862 (2007).
-
(2007)
N. Engl. J. Med
, vol.357
, pp. 851-862
-
-
-
56
-
-
67649876123
-
Meta-analysis of genome scans and replication identify CD6 IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci
-
De Jager, P. L., et al. Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nat. Genet. 41, 776-782 (2009).
-
(2009)
Nat. Genet
, vol.41
, pp. 776-782
-
-
De Jager, P.L.1
-
57
-
-
84969213492
-
Genome-wide association study of 14, 000 cases of seven common diseases and 3, 000 shared controls
-
WTCCC Consortium. Genome-wide association study of 14, 000 cases of seven common diseases and 3, 000 shared controls. Nature 447, 661-678 (2007).
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
Consortium, W.1
-
58
-
-
34447515621
-
Variants conferring risk of atrial fibrillation on chromosome 4q25
-
Gudbjartsson, D. F., et al. Variants conferring risk of atrial fibrillation on chromosome 4q25. Nature 448, 353-357 (2007).
-
(2007)
Nature
, vol.448
, pp. 353-357
-
-
Gudbjartsson, D.F.1
-
59
-
-
68149137739
-
A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke
-
Gudbjartsson, D. F., et al. A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke. Nat. Genet. 41, 876-878 (2009).
-
(2009)
Nat. Genet
, vol.41
, pp. 876-878
-
-
Gudbjartsson, D.F.1
-
60
-
-
52949111858
-
Common variants at CD40 and other loci confer risk of rheumatoid arthritis
-
Raychaudhuri, S., et al. Common variants at CD40 and other loci confer risk of rheumatoid arthritis. Nat. Genet. 40, 1216-1223 (2008).
-
(2008)
Nat. Genet
, vol.40
, pp. 1216-1223
-
-
Raychaudhuri, S.1
-
61
-
-
84890107642
-
Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data
-
Denny, J. C., et al. Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data. Nat. Biotechnol. 31, 1102-1111 (2013).
-
(2013)
Nat. Biotechnol
, vol.31
, pp. 1102-1111
-
-
Denny, J.C.1
-
62
-
-
84898754281
-
Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE GECCO and CCFR consortia
-
Cheng, I., et al. Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE, GECCO and CCFR consortia. Gut 63, 800-807 (2014).
-
(2014)
Gut
, vol.63
, pp. 800-807
-
-
Cheng, I.1
-
63
-
-
84898899793
-
Pleiotropic associations of risk variants identified for other cancers with lung cancer risk: The PAGE and TRICL consortia
-
dju061
-
Park, S. L., et al. Pleiotropic associations of risk variants identified for other cancers with lung cancer risk: the PAGE and TRICL consortia. J. Natl Cancer Inst. 106, dju061 (2014).
-
(2014)
J. Natl Cancer Inst
, vol.106
-
-
Park, S.L.1
-
64
-
-
84906837946
-
Cross-cancer pleiotropic analysis of endometrial cancer: PAGE and E2C2 consortia
-
Setiawan, V. W., et al. Cross-cancer pleiotropic analysis of endometrial cancer: PAGE and E2C2 consortia. Carcinogenesis 35, 2068-2073 (2014).
-
(2014)
Carcinogenesis
, vol.35
, pp. 2068-2073
-
-
Setiawan, V.W.1
-
65
-
-
84920201767
-
Association of cancer susceptibility variants with risk of multiple primary cancers: The Population Architecture using Genomics and Epidemiology study
-
Park, S. L., et al. Association of cancer susceptibility variants with risk of multiple primary cancers: the Population Architecture using Genomics and Epidemiology study. Cancer Epidemiol. Biomarkers Prev. 23, 2568-2578 (2014).
-
(2014)
Cancer Epidemiol. Biomarkers Prev
, vol.23
, pp. 2568-2578
-
-
Park, S.L.1
-
66
-
-
84925690205
-
Pleiotropic and sex-specific effects of cancer GWAS SNPs on melanoma risk in the Population Architecture Using Genomics and Epidemiology (PAGE) study
-
Kocarnik, J. M., et al. Pleiotropic and sex-specific effects of cancer GWAS SNPs on melanoma risk in the Population Architecture Using Genomics and Epidemiology (PAGE) study. PLoS ONE 10, e0120491 (2015).
-
(2015)
PLoS ONE
, vol.10
, pp. e0120491
-
-
Kocarnik, J.M.1
-
67
-
-
79959912879
-
Genome-wide pleiotropy scan identifies HNF1A region as a novel pancreatic cancer susceptibility locus
-
Pierce, B. L. & Ahsan, H. Genome-wide pleiotropy scan identifies HNF1A region as a novel pancreatic cancer susceptibility locus. Cancer Res. 71, 4352-4358 (2011).
-
(2011)
Cancer Res
, vol.71
, pp. 4352-4358
-
-
Pierce, B.L.1
Ahsan, H.2
-
68
-
-
84895801008
-
A genome-wide pleiotropy scan does not identify new susceptibility for estrogen receptor negative breast cancer
-
Campa, D., et al. A genome-wide pleiotropy scan does not identify new susceptibility for estrogen receptor negative breast cancer. PLoS ONE 9, e85955 (2014).
-
(2014)
PLoS ONE
, vol.9
, pp. e85955
-
-
Campa, D.1
-
69
-
-
84923075918
-
A genome-wide pleiotropy scan for prostate cancer risk
-
Panagiotou, O. A., et al. A genome-wide pleiotropy scan for prostate cancer risk. Eur. Urol. 67, 649-657 (2015).
-
(2015)
Eur. Urol
, vol.67
, pp. 649-657
-
-
Panagiotou, O.A.1
-
70
-
-
80052325959
-
Pervasive sharing of genetic effects in autoimmune disease
-
Cotsapas, C., et al. Pervasive sharing of genetic effects in autoimmune disease. PLoS Genet. 7, e1002254 (2011).
-
(2011)
PLoS Genet
, vol.7
, pp. e1002254
-
-
Cotsapas, C.1
-
71
-
-
79958154438
-
The use of phenome-wide association studies (PheWAS) for exploration of novel genotype-phenotype relationships and pleiotropy discovery
-
Pendergrass, S. A., et al. The use of phenome-wide association studies (PheWAS) for exploration of novel genotype-phenotype relationships and pleiotropy discovery. Genet. Epidemiol. 35, 410-422 (2011).
-
(2011)
Genet. Epidemiol
, vol.35
, pp. 410-422
-
-
Pendergrass, S.A.1
-
72
-
-
84906273890
-
R PheWAS: Data analysis and plotting tools for phenome-wide association studies in the R environment
-
Carroll, R. J., Bastarache, L. & Denny, J. C. R PheWAS: data analysis and plotting tools for phenome-wide association studies in the R environment. Bioinformatics 30, 2375-2376 (2014).
-
(2014)
Bioinformatics
, vol.30
, pp. 2375-2376
-
-
Carroll, R.J.1
Bastarache, L.2
Denny, J.C.3
-
73
-
-
84947060384
-
MR PheWAS: Hypothesis prioritization among potential causal effects of body mass index on many outcomes, using Mendelian randomization
-
Millard, L. A. C., et al. MR PheWAS: hypothesis prioritization among potential causal effects of body mass index on many outcomes, using Mendelian randomization. Sci. Rep. 5, 16645 (2015).
-
(2015)
Sci. Rep
, vol.5
, pp. 16645
-
-
Millard, L.A.C.1
-
74
-
-
80053206058
-
The next PAGE in understanding complex traits: Design for the analysis of population architecture using genetics and epidemiology (PAGE) study
-
Matise, T. C., et al. The next PAGE in understanding complex traits: design for the analysis of population architecture using genetics and epidemiology (PAGE) study. Am. J. Epidemiol. 174, 849-859 (2011).
-
(2011)
Am. J. Epidemiol
, vol.174
, pp. 849-859
-
-
Matise, T.C.1
-
75
-
-
65249183403
-
Meta-analysis in genome-wide association studies
-
Zeggini, E. & Ioannidis, J. P. Meta-analysis in genome-wide association studies. Pharmacogenomics 10, 191-201 (2009).
-
(2009)
Pharmacogenomics
, vol.10
, pp. 191-201
-
-
Zeggini, E.1
Ioannidis, J.P.2
-
76
-
-
84878020180
-
Meta-analysis methods for genome-wide association studies and beyond
-
Evangelou, E. & Ioannidis, J. P. A. Meta-analysis methods for genome-wide association studies and beyond. Nat. Rev. Genet. 14, 379-389 (2013).
-
(2013)
Nat. Rev. Genet
, vol.14
, pp. 379-389
-
-
Evangelou, E.1
Ioannidis, J.P.A.2
-
77
-
-
84895868553
-
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
-
DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium et al.
-
DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium et al. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat. Genet. 46, 234-244 (2014).
-
(2014)
Nat. Genet
, vol.46
, pp. 234-244
-
-
-
78
-
-
79959835081
-
Genetic determinants of lipid traits in diverse populations from the Population Architecture using Genomics and Epidemiology (PAGE) study
-
Dumitrescu, L., et al. Genetic determinants of lipid traits in diverse populations from the Population Architecture using Genomics and Epidemiology (PAGE) study. PLoS Genet. 7, e1002138 (2011).
-
(2011)
PLoS Genet
, vol.7
, pp. e1002138
-
-
Dumitrescu, L.1
-
79
-
-
58149163149
-
Common variants at 30 loci contribute to polygenic dyslipidemia
-
Kathiresan, S., et al. Common variants at 30 loci contribute to polygenic dyslipidemia. Nat. Genet. 41, 56-65 (2009).
-
(2009)
Nat. Genet
, vol.41
, pp. 56-65
-
-
Kathiresan, S.1
-
80
-
-
84919624872
-
Detection of pleiotropy through a phenome-wide association study (PheWAS) of epidemiologic data as part of the Environmental Architecture for Genes Linked to Environment (EAGLE) Study
-
Hall, M. A., et al. Detection of pleiotropy through a phenome-wide association study (PheWAS) of epidemiologic data as part of the Environmental Architecture for Genes Linked to Environment (EAGLE) Study. PLoS Genet. 10, e1004678 (2014).
-
(2014)
PLoS Genet
, vol.10
, pp. e1004678
-
-
Hall, M.A.1
-
81
-
-
84899585453
-
Investigating the relationship between mitochondrial genetic variation and cardiovascular-related traits to develop a framework for mitochondrial phenome-wide association studies
-
Mitchell, S., et al. Investigating the relationship between mitochondrial genetic variation and cardiovascular-related traits to develop a framework for mitochondrial phenome-wide association studies. BioData Min. 7, 6 (2014).
-
(2014)
BioData Min
, vol.7
, pp. 6
-
-
Mitchell, S.1
-
82
-
-
84861958505
-
Visually integrating and exploring high throughput phenome-wide association study (PheWAS) results using PheWAS-View
-
Pendergrass, S., Dudek, S., Crawford, D. & Ritchie, M. Visually integrating and exploring high throughput phenome-wide association study (PheWAS) results using PheWAS-View. BioData Min. 5, 5 (2014).
-
(2014)
BioData Min
, vol.5
, pp. 5
-
-
Pendergrass, S.1
Dudek, S.2
Crawford, D.3
Ritchie, M.4
-
83
-
-
84902596890
-
GWAS in a box: Statistical and visual analytics of structured associations via GenAMap
-
Xing, E. P., et al. GWAS in a box: statistical and visual analytics of structured associations via GenAMap. PLoS ONE 9, e97524 (2014).
-
(2014)
PLoS ONE
, vol.9
, pp. e97524
-
-
Xing, E.P.1
-
84
-
-
84877327584
-
BioBin: A bioinformatics tools for automating the binning of rare variants using publicly available biological knowledge
-
Moore, C. B., Wallace, J. R., Frase, A. T., Pendergrass, S. A. & Ritchie, M. D. BioBin: a bioinformatics tools for automating the binning of rare variants using publicly available biological knowledge. BMC Med Genomics 6, S6 (2013).
-
(2013)
BMC Med Genomics
, vol.6
, pp. S6
-
-
Moore, C.B.1
Wallace, J.R.2
Frase, A.T.3
Pendergrass, S.A.4
Ritchie, M.D.5
-
85
-
-
84905264016
-
Pleiotropic genes for metabolic syndrome and inflammation
-
Kraja, A. T., et al. Pleiotropic genes for metabolic syndrome and inflammation. Mol. Genet. Metab. 112, 317-338 (2014).
-
(2014)
Mol. Genet. Metab
, vol.112
, pp. 317-338
-
-
Kraja, A.T.1
-
86
-
-
84873488838
-
Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network
-
Pendergrass, S. A., et al. Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network. PLoS Genet. 9, e1003087 (2013).
-
(2013)
PLoS Genet
, vol.9
, pp. e1003087
-
-
Pendergrass, S.A.1
-
87
-
-
84947866716
-
Towards a phenome-wide catalog of human clinical traits impacted by genetic ancestry
-
Dumitrescu, L., et al. Towards a phenome-wide catalog of human clinical traits impacted by genetic ancestry. BioData Min. 8, 35 (2015).
-
(2015)
BioData Min
, vol.8
, pp. 35
-
-
Dumitrescu, L.1
-
88
-
-
77951133654
-
Genome-wide association studies in diverse populations
-
Rosenberg, N. A., et al. Genome-wide association studies in diverse populations. Nat. Rev. Genet. 11, 356-366 (2010).
-
(2010)
Nat. Rev. Genet
, vol.11
, pp. 356-366
-
-
Rosenberg, N.A.1
-
89
-
-
84931427223
-
Planning for US Precision Medicine Initiative underway
-
Jaffe, S. Planning for US Precision Medicine Initiative underway. Lancet 385, 2448-2449 (2015).
-
(2015)
Lancet
, vol.385
, pp. 2448-2449
-
-
Jaffe, S.1
-
90
-
-
84880328448
-
Prevalence of actinic keratosis and its risk factors in the general population: The Rotterdam Study
-
Flohil, S. C., et al. Prevalence of actinic keratosis and its risk factors in the general population: The Rotterdam Study. J. Invest. Dermatol. 133, 1971-1978 (2013).
-
(2013)
J. Invest. Dermatol
, vol.133
, pp. 1971-1978
-
-
Flohil, S.C.1
-
91
-
-
44849091227
-
A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation
-
Han, J., et al. A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation. PLoS Genet. 4, e1000074 (2008).
-
(2008)
PLoS Genet
, vol.4
, pp. e1000074
-
-
Han, J.1
-
92
-
-
77954167176
-
Web-based, participant-driven studies yield novel genetic associations for common traits
-
Eriksson, N., et al. Web-based, participant-driven studies yield novel genetic associations for common traits. PLoS Genet. 6, e1000993 (2010).
-
(2010)
PLoS Genet
, vol.6
, pp. e1000993
-
-
Eriksson, N.1
-
93
-
-
84880271272
-
Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans
-
Zhang, M., et al. Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans. Hum. Mol. Genet. 22, 2948-2959 (2013).
-
(2013)
Hum. Mol. Genet
, vol.22
, pp. 2948-2959
-
-
Zhang, M.1
-
94
-
-
84930730324
-
IRF4 MC1R and TYR genes are risk factors for actinic keratosis independent of skin color
-
Jacobs, L. C., et al. IRF4, MC1R and TYR genes are risk factors for actinic keratosis independent of skin color. Hum. Mol. Genet. 24, 3296-3303 (2015).
-
(2015)
Hum. Mol. Genet
, vol.24
, pp. 3296-3303
-
-
Jacobs, L.C.1
-
95
-
-
80051968181
-
Needles in stacks of needles: Finding disease-causal variants in a wealth of genomic data
-
Cooper, G. M. & Shendure, J. Needles in stacks of needles: finding disease-causal variants in a wealth of genomic data. Nat. Rev. Genet. 12, 628-640 (2011).
-
(2011)
Nat. Rev. Genet
, vol.12
, pp. 628-640
-
-
Cooper, G.M.1
Shendure, J.2
-
96
-
-
84946934930
-
A GWAS study on liver function test using eMERGE network participants
-
Namjou, B., et al. A GWAS study on liver function test using eMERGE network participants. PLoS ONE 10, e0138677 (2015).
-
(2015)
PLoS ONE
, vol.10
, pp. e0138677
-
-
Namjou, B.1
-
97
-
-
80053896220
-
Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: Using electronic medical records for genome- and phenome-wide studies
-
Denny, J. C., et al. Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome- and phenome-wide studies. Am. J. Hum. Genet. 89, 529-542 (2011).
-
(2011)
Am. J. Hum. Genet
, vol.89
, pp. 529-542
-
-
Denny, J.C.1
-
98
-
-
84876907114
-
PheWAS approach in studying HLA DRB1∗1501
-
Hebbring, S. J., et al. PheWAS approach in studying HLA DRB1∗1501. Genes Immun. 14, 187-191 (2013).
-
(2013)
Genes Immun
, vol.14
, pp. 187-191
-
-
Hebbring, S.J.1
-
99
-
-
84906233384
-
Phenome wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index
-
Cronin, R. M., et al. Phenome wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index. Front. Genet. 5, 250 (2014).
-
(2014)
Front. Genet
, vol.5
, pp. 250
-
-
Cronin, R.M.1
-
100
-
-
84891858260
-
A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects
-
Shameer, K., et al. A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects. Hum. Genet. 133, 95-109 (2014).
-
(2014)
Hum. Genet
, vol.133
, pp. 95-109
-
-
Shameer, K.1
-
101
-
-
84927518293
-
Phenome-wide association study (PheWAS) in EMR-linked pediatric cohorts, genetically links PLCL1 to speech language development and IL5 IL13 to eosinophilic esophagitis
-
Namjou, B., et al. Phenome-wide association study (PheWAS) in EMR-linked pediatric cohorts, genetically links PLCL1 to speech language development and IL5 IL13 to eosinophilic esophagitis. Front. Genet. 5, 401 (2014).
-
(2014)
Front. Genet
, vol.5
, pp. 401
-
-
Namjou, B.1
-
102
-
-
84924726240
-
Phenome-wide association studies (PheWASs) for functional variants
-
Ye, Z., et al. Phenome-wide association studies (PheWASs) for functional variants. Eur. J. Hum. Genet. 23, 523-529 (2015).
-
(2015)
Eur. J. Hum. Genet
, vol.23
, pp. 523-529
-
-
Ye, Z.1
-
103
-
-
84874435155
-
Associations of autoantibodies, autoimmune risk alleles, and clinical diagnoses from the electronic medical records in rheumatoid arthritis cases and non-rheumatoid arthritis controls
-
Liao, K. P., et al. Associations of autoantibodies, autoimmune risk alleles, and clinical diagnoses from the electronic medical records in rheumatoid arthritis cases and non-rheumatoid arthritis controls. Arthritis Rheum. 65, 571-581 (2013).
-
(2013)
Arthritis Rheum
, vol.65
, pp. 571-581
-
-
Liao, K.P.1
-
104
-
-
84892743778
-
Phenome-wide association studies on a quantitative trait: Application to TPMT enzyme activity and thiopurine therapy in pharmacogenomics
-
Neuraz, A., et al. Phenome-wide association studies on a quantitative trait: application to TPMT enzyme activity and thiopurine therapy in pharmacogenomics. PLoS Comput. Biol. 9, e1003405 (2013).
-
(2013)
PLoS Comput. Biol
, vol.9
, pp. e1003405
-
-
Neuraz, A.1
-
105
-
-
84938084278
-
Metrics and tools for consistent cohort discovery and financial analyses post-transition to ICD 10 CM
-
Boyd, A. D., et al. Metrics and tools for consistent cohort discovery and financial analyses post-transition to ICD 10 CM. J. Am. Med. Inform. Assoc. 22, 730-737 (2015).
-
(2015)
J. Am. Med. Inform. Assoc
, vol.22
, pp. 730-737
-
-
Boyd, A.D.1
-
106
-
-
84934282787
-
ICD 10 CM Crosswalks in the primary care setting: Assessing reliability of the GEMs and reimbursement mappings
-
Turer, R. W., Zuckowsky, T. D., Causey, H. J. & Rosenbloom, S. T. ICD 10 CM Crosswalks in the primary care setting: assessing reliability of the GEMs and reimbursement mappings. J. Am. Med. Inform. Assoc. 22, 417-425 (2015).
-
(2015)
J. Am. Med. Inform. Assoc
, vol.22
, pp. 417-425
-
-
Turer, R.W.1
Zuckowsky, T.D.2
Causey, H.J.3
Rosenbloom, S.T.4
-
107
-
-
84931043092
-
Application of clinical text data for phenome-wide association studies (PheWASs
-
Hebbring, S. J., et al. Application of clinical text data for phenome-wide association studies (PheWASs). Bioinformatics 31, 1981-1987 (2015).
-
(2015)
Bioinformatics
, vol.31
, pp. 1981-1987
-
-
Hebbring, S.J.1
-
108
-
-
33845985619
-
Accuracy of administrative coding for type 2 diabetes in children, adolescents, and young adults
-
Rhodes, E. T., Laffel, L. M. B., Gonzalez, T. V. & Ludwig, D. S. Accuracy of administrative coding for type 2 diabetes in children, adolescents, and young adults. Diabetes Care 30, 141-143 (2007).
-
(2007)
Diabetes Care
, vol.30
, pp. 141-143
-
-
Rhodes, E.T.1
Laffel, L.M.B.2
Gonzalez, T.V.3
Ludwig, D.S.4
-
109
-
-
84890541415
-
A comparison of phenotype definitions for diabetes mellitus
-
Richesson, R. L., et al. A comparison of phenotype definitions for diabetes mellitus. J. Am. Med. Inform. Assoc. 20, e319-e326 (2013).
-
(2013)
J. Am. Med. Inform. Assoc
, vol.20
, pp. e319-e326
-
-
Richesson, R.L.1
-
110
-
-
77950338000
-
Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record
-
Ritchie, M. D., et al. Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record. Am. J. Hum. Genet. 86, 560-572 (2010).
-
(2010)
Am. J. Hum. Genet
, vol.86
, pp. 560-572
-
-
Ritchie, M.D.1
-
111
-
-
85012150933
-
Testing population-specific quantitative trait associations for clinical outcome relevance in a biorepository linked to electronic health records: LPA and myocardial infarction in African Americans
-
Dumitrescu, L., Diggins, K. E., Goodloe, R. & Crawford, D. C. Testing population-specific quantitative trait associations for clinical outcome relevance in a biorepository linked to electronic health records: LPA and myocardial infarction in African Americans. Pac. Symp. Biocomput. 21, 96-107 (2016).
-
(2016)
Pac. Symp. Biocomput
, vol.21
, pp. 96-107
-
-
Dumitrescu, L.1
Diggins, K.E.2
Goodloe, R.3
Crawford, D.C.4
-
113
-
-
84882752871
-
ICD 9 tobacco use codes are effective identifiers of smoking status
-
Wiley, L. K., Shah, A., Xu, H. & Bush, W. S. ICD 9 tobacco use codes are effective identifiers of smoking status. J. Am. Med. Inform. Assoc. 20, 652-658 (2013).
-
(2013)
J. Am. Med. Inform. Assoc
, vol.20
, pp. 652-658
-
-
Wiley, L.K.1
Shah, A.2
Xu, H.3
Bush, W.S.4
-
114
-
-
84905884395
-
Utilization of an EMR-biorepository to identify the genetic predictors of calcineurin-inhibitor toxicity in heart transplant recipients
-
Oetjens, M., et al. Utilization of an EMR-biorepository to identify the genetic predictors of calcineurin-inhibitor toxicity in heart transplant recipients. Pac. Symp. Biocomput 2014, 253-264 (2014).
-
(2014)
Pac. Symp. Biocomput 2014
, pp. 253-264
-
-
Oetjens, M.1
-
115
-
-
84936855143
-
Extracting primary open-angle glaucoma from electronic medical records for genetic association studies
-
Restrepo, N. A., Farber-Eger, E., Goodloe, R., Haines, J. L. & Crawford, D. C. Extracting primary open-angle glaucoma from electronic medical records for genetic association studies. PLoS ONE 10, e0127817 (2015).
-
(2015)
PLoS ONE
, vol.10
, pp. e0127817
-
-
Restrepo, N.A.1
Farber-Eger, E.2
Goodloe, R.3
Haines, J.L.4
Crawford, D.C.5
-
116
-
-
84890524645
-
Automated extraction of clinical traits of multiple sclerosis in electronic medical records
-
Davis, M. F. Sriram, S., Bush, W. S., Denny, J. C. & Haines, J. L. Automated extraction of clinical traits of multiple sclerosis in electronic medical records. J. Am. Med. Inform. Assoc. 20, e334-e340 (2013)
-
(2013)
J. Am. Med. Inform. Assoc
, vol.20
, pp. e334-e340
-
-
Davis Sriram F M, S.1
Bush, W.S.2
Denny, J.C.3
Haines, J.L.4
-
117
-
-
33947224159
-
Construction of atorvastatin dose-response relationships using data from a large population-based DNA biobank
-
Peissig, P., et al. Construction of atorvastatin dose-response relationships using data from a large population-based DNA biobank. Bas. Clin. Pharmacol. Toxicol. 100, 286-288 (2007
-
(2007)
Bas. Clin. Pharmacol. Toxicol
, vol.100
, pp. 286-288
-
-
Peissig, P.1
-
118
-
-
84934290752
-
Seeing the forest through the trees: Uncovering phenomic complexity through interactive network visualization
-
Warner, J. L., Denny, J. C., Kreda, D. A. & Alterovitz, G. Seeing the forest through the trees: uncovering phenomic complexity through interactive network visualization. J. Am. Med. Inform. Assoc. 22, 324-329 (2015).
-
(2015)
J. Am. Med. Inform. Assoc
, vol.22
, pp. 324-329
-
-
Warner, J.L.1
Denny, J.C.2
Kreda, D.A.3
Alterovitz, G.4
-
119
-
-
84954218290
-
Toward high-throughput phenotyping: Unbiased automated feature extraction and selection from knowledge sources
-
Yu, S., et al. Toward high-throughput phenotyping: unbiased automated feature extraction and selection from knowledge sources. J. Am. Med. Inform. Assoc. 22, 993-1000 (2015).
-
(2015)
J. Am. Med. Inform. Assoc
, vol.22
, pp. 993-1000
-
-
Yu, S.1
-
120
-
-
84879468407
-
Computational phenotype discovery using unsupervised feature learning over noisy, sparse, and irregular clinical data
-
Lasko, T. A., Denny, J. C. & Levy, M. A. Computational phenotype discovery using unsupervised feature learning over noisy, sparse, and irregular clinical data. PLoS ONE 8, e66341 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e66341
-
-
Lasko, T.A.1
Denny, J.C.2
Levy, M.A.3
-
121
-
-
84922211548
-
Finding our way through phenotypes
-
Deans, A. R., et al. Finding our way through phenotypes. PLoS Biol. 13, e1002033 (2015).
-
(2015)
PLoS Biol
, vol.13
, pp. e1002033
-
-
Deans, A.R.1
-
122
-
-
79952503255
-
Phenotype harmonization and cross-study collaboration in GWAS consortia: The GENEVA experience
-
Bennett, S. N., et al. Phenotype harmonization and cross-study collaboration in GWAS consortia: the GENEVA experience. Genet. Epidemiol. 35, 159-173 (2011).
-
(2011)
Genet. Epidemiol
, vol.35
, pp. 159-173
-
-
Bennett, S.N.1
-
123
-
-
84862993403
-
Facilitating collaborative research: Implementing a platform supporting data harmonization and pooling
-
Doiron, D., Raina, P., Ferretti, V., L'Heureux, F. & Fortier, I. Facilitating collaborative research: implementing a platform supporting data harmonization and pooling. Nor. Epidemiol. 21, 221-224 (2012).
-
(2012)
Nor. Epidemiol
, vol.21
, pp. 221-224
-
-
Doiron, D.1
Raina, P.2
Ferretti, V.3
L'Heureux, F.4
Fortier, I.5
-
124
-
-
84958599888
-
Strategies for handling missing data in electronic health record derived data
-
Wells, B. J., Chagin, K. M., Nowacki, A. S. & Kattan, M. W. Strategies for handling missing data in electronic health record derived data. EGEMS (Wash. DC) 1, 1035 (2013).
-
(2013)
EGEMS (Wash. DC)
, vol.1
, pp. 1035
-
-
Wells, B.J.1
Chagin, K.M.2
Nowacki, A.S.3
Kattan, M.W.4
-
125
-
-
80055080543
-
A phenomics-based strategy identifies loci on APOC1 BRAP and PLCG1 associated with metabolic syndrome phenotype domains
-
Avery, C. L., et al. A phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains. PLoS Genet. 7, e1002322 (2011).
-
(2011)
PLoS Genet
, vol.7
, pp. e1002322
-
-
Avery, C.L.1
-
126
-
-
70450223891
-
Common disorders are quantitative traits
-
Plomin, R., Haworth, C. M. A. & Davis, O. S. P. Common disorders are quantitative traits. Nat. Rev. Genet. 10, 872-878 (2009).
-
(2009)
Nat. Rev. Genet
, vol.10
, pp. 872-878
-
-
Plomin, R.1
Haworth, C.M.A.2
Davis, O.S.P.3
-
127
-
-
84908890496
-
Defining the role of common variation in the genomic and biological architecture of adult human height
-
Wood, A. R., et al. Defining the role of common variation in the genomic and biological architecture of adult human height. Nat. Genet. 46, 1173-1186 (2014).
-
(2014)
Nat. Genet
, vol.46
, pp. 1173-1186
-
-
Wood, A.R.1
-
128
-
-
84923171580
-
Genetic studies of body mass index yield new insights for obesity biology
-
Locke, A. E., et al. Genetic studies of body mass index yield new insights for obesity biology. Nature 518, 197-206 (2015).
-
(2015)
Nature
, vol.518
, pp. 197-206
-
-
Locke, A.E.1
-
129
-
-
84901285890
-
A rigorous algorithm to detect and clean inaccurate adult height records within EHR systems
-
Muthalagu, A., et al. A rigorous algorithm to detect and clean inaccurate adult height records within EHR systems. Appl. Clin. Inform. 5, 118-126 (2014).
-
(2014)
Appl. Clin. Inform
, vol.5
, pp. 118-126
-
-
Muthalagu, A.1
-
130
-
-
84988877020
-
Extraction of echocardiographic data from the electronic medical record is a rapid and efficient method for study of cardiac structure and function
-
Wells, Q., Farber-Eger, E. & Crawford, D. Extraction of echocardiographic data from the electronic medical record is a rapid and efficient method for study of cardiac structure and function. J. Clin. Bioinforma. 4, 12 (2014).
-
(2014)
J. Clin. Bioinforma
, vol.4
, pp. 12
-
-
Wells, Q.1
Farber-Eger, E.2
Crawford, D.3
-
131
-
-
0037126526
-
Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
-
National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Adult Treatment Panel III) Final Report
-
National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Final Report. Circulation 106, 3143-3421 (2002).
-
(2002)
Circulation
, vol.106
, pp. 3143-3421
-
-
-
132
-
-
34548516061
-
Identifying patient smoking status from medical discharge records
-
Uzuner, O., Goldstein, I., Luo, Y. & Kohane, I. Identifying patient smoking status from medical discharge records. J. Am. Med. Inform. Assoc. 15, 14-24 (2008).
-
(2008)
J. Am. Med. Inform. Assoc
, vol.15
, pp. 14-24
-
-
Uzuner, O.1
Goldstein, I.2
Luo, Y.3
Kohane, I.4
-
133
-
-
63449125469
-
Linkage of the Third National Health and Nutrition Examination Survey to air quality data
-
Kravets, N. & Parker, J. D. Linkage of the Third National Health and Nutrition Examination Survey to air quality data. Vital Health Stat 2 149, 1-16, (2008).
-
(2008)
Vital Health Stat
, vol.2
, Issue.149
, pp. 1-16
-
-
Kravets, N.1
Parker, J.D.2
-
134
-
-
84872779746
-
Linkage of the 1999-2008 National Health and Nutrition Examination Surveys to traffic indicators from the National Highway Planning Network
-
Parker, J. D., Kravets, N., Nachman, K. & Sapkota, A. Linkage of the 1999-2008 National Health and Nutrition Examination Surveys to traffic indicators from the National Highway Planning Network. Natl Health Stat. Rep. 45, 1-16 (2012).
-
(2012)
Natl Health Stat. Rep
, vol.45
, pp. 1-16
-
-
Parker, J.D.1
Kravets, N.2
Nachman, K.3
Sapkota, A.4
-
135
-
-
84892407793
-
Validation of PhenX measures in the personalized medicine research project for use in gene/ environment studies
-
McCarty, C., et al. Validation of PhenX measures in the personalized medicine research project for use in gene/ environment studies. BMC Medical Genomics 7, 3 (2014).
-
(2014)
BMC Medical Genomics
, vol.7
, pp. 3
-
-
McCarty, C.1
-
136
-
-
79251591943
-
Dietary intake in the Personalized Medicine Research Project: A resource for studies of gene-diet interaction
-
Strobush, L., et al. Dietary intake in the Personalized Medicine Research Project: a resource for studies of gene-diet interaction. Nutr. J. 10, 13 (2011).
-
(2011)
Nutr. J.
, vol.10
, pp. 13
-
-
Strobush, L.1
-
137
-
-
84901191649
-
Community-level determinants of obesity: Harnessing the power of electronic health records for retrospective data analysis
-
Roth, C., Foraker, R., Payne, P. & Embi, P. Community-level determinants of obesity: harnessing the power of electronic health records for retrospective data analysis. BMC Med. Inform. Decis. Mak. 14, 36 (2014).
-
(2014)
BMC Med. Inform. Decis. Mak
, vol.14
, pp. 36
-
-
Roth, C.1
Foraker, R.2
Payne, P.3
Embi, P.4
-
138
-
-
80053366077
-
Body mass index and the built and social environments in children and adolescents using electronic health records
-
Schwartz, B. S., et al. Body mass index and the built and social environments in children and adolescents using electronic health records. Am. J. Prev. Med. 41, e17-e28 (2011).
-
(2011)
Am. J. Prev. Med
, vol.41
, pp. e17-e28
-
-
Schwartz, B.S.1
-
139
-
-
84905890259
-
Environment-wide association study (EWAS) for type 2 diabetes in the Marshfield Personalized Medicine Research Project Biobank
-
2014
-
Hall, M. A., et al. Environment-wide association study (EWAS) for type 2 diabetes in the Marshfield Personalized Medicine Research Project Biobank. Pac. Symp. Biocomput. 2014, 200-211 (2014).
-
(2014)
Pac. Symp. Biocomput
, pp. 200-211
-
-
Hall, M.A.1
-
140
-
-
77953886372
-
An environment-wide association study (EWAS) on type 2 diabetes mellitus
-
Patel, C. J., Bhattacharya, J. & Butte, A. J. An environment-wide association study (EWAS) on type 2 diabetes mellitus. PLoS ONE 5, e10746 (2010).
-
(2010)
PLoS ONE
, vol.5
, pp. e10746
-
-
Patel, C.J.1
Bhattacharya, J.2
Butte, A.J.3
-
141
-
-
84876500725
-
Systematic identification of interaction effects between genome- and environment-wide associations in type 2 diabetes mellitus
-
Patel, C., Chen, R., Kodama, K., Ioannidis, J. & Butte, A. Systematic identification of interaction effects between genome- and environment-wide associations in type 2 diabetes mellitus. Hum. Genet. 132, 495-508 (2013).
-
(2013)
Hum. Genet
, vol.132
, pp. 495-508
-
-
Patel, C.1
Chen, R.2
Kodama, K.3
Ioannidis, J.4
Butte, A.5
-
142
-
-
84971326365
-
Development of exposome correlation globes to map out environment-wide associations
-
Patel, C. J. & Manrai, A. K. Development of exposome correlation globes to map out environment-wide associations. Pac. Symp. Biocomput 2015, 231-242 (2015).
-
(2015)
Pac. Symp. Biocomput
, vol.2015
, pp. 231-242
-
-
Patel, C.J.1
Manrai, A.K.2
-
143
-
-
84858433310
-
Personal omics profiling reveals dynamic molecular and medical phenotypes
-
Chen, R., et al. Personal omics profiling reveals dynamic molecular and medical phenotypes. Cell 148, 1293-1307 (2012).
-
(2012)
Cell
, vol.148
, pp. 1293-1307
-
-
Chen, R.1
-
144
-
-
84924295546
-
Incorporating temporal EHR data in predictive models for risk stratification of renal function deterioration
-
Singh, A., et al. Incorporating temporal EHR data in predictive models for risk stratification of renal function deterioration. J. Biomed. Inform. 53, 220-228 (2015).
-
(2015)
J. Biomed. Inform
, vol.53
, pp. 220-228
-
-
Singh, A.1
-
145
-
-
84914815797
-
Generalized estimating equations for genome-wide association studies using longitudinal phenotype data
-
Sitlani, C. M., et al. Generalized estimating equations for genome-wide association studies using longitudinal phenotype data. Stat. Med. 34, 118-130 (2015).
-
(2015)
Stat. Med
, vol.34
, pp. 118-130
-
-
Sitlani, C.M.1
-
146
-
-
84978328033
-
Phenome-wide association study relating pretreatment laboratory parameters with human genetic variants in AIDS clinical trails group protocols
-
ofu113
-
Moore, C. B., et al. Phenome-wide association study relating pretreatment laboratory parameters with human genetic variants in AIDS clinical trails group protocols. Open Forum Infect. Dis. 2, ofu113 (2015).
-
(2015)
Open Forum Infect. Dis
, vol.2
-
-
Moore, C.B.1
-
147
-
-
77950477064
-
MedEx: A medication information extraction system for clinical narratives
-
Xu, H., et al. MedEx: a medication information extraction system for clinical narratives. J. Am. Med. Inform. Assoc. 17, 19-24 (2010).
-
(2010)
J. Am. Med. Inform. Assoc
, vol.17
, pp. 19-24
-
-
Xu, H.1
-
148
-
-
84906323732
-
MedXN: An open source medication extraction and normalization tool for clinical text
-
Sohn, S., et al. MedXN: an open source medication extraction and normalization tool for clinical text. J. Am. Med. Inform. Assoc. 21, 858-865 (2014).
-
(2014)
J. Am. Med. Inform. Assoc
, vol.21
, pp. 858-865
-
-
Sohn, S.1
-
149
-
-
79959652930
-
Normalized names for clinical drugs: RxNorm at 6 years
-
Nelson, S. J., Zeng, K., Kilbourne, J., Powell, T. & Moore, R. Normalized names for clinical drugs: RxNorm at 6 years. J. Am. Med. Inform. Assoc. 18, 441-448 (2011).
-
(2011)
J. Am. Med. Inform. Assoc
, vol.18
, pp. 441-448
-
-
Nelson, S.J.1
Zeng, K.2
Kilbourne, J.3
Powell, T.4
Moore, R.5
-
150
-
-
79953317220
-
Study newsletters, community and ethics advisory boards, and focus group discussions provide ongoing feedback for a large biobank
-
Personalized Medicine Research Project Community Advisory Group and Ethics and Security Advisory Board
-
McCarty C. A., Garber, A., Reeser, J. C., Fost, N. C. & Personalized Medicine Research Project Community Advisory Group and Ethics and Security Advisory Board. Study newsletters, community and ethics advisory boards, and focus group discussions provide ongoing feedback for a large biobank. Am. J. Med. Genet. 155, 737-741 (2011).
-
(2011)
Am. J. Med. Genet
, vol.155
, pp. 737-741
-
-
McCarty, C.A.1
Garber, A.2
Reeser, J.C.3
Fost, N.C.4
-
151
-
-
84862536361
-
Informed consent: A broken contract
-
Hayden, E. C. Informed consent: a broken contract. Nature 486, 312-314 (2012).
-
(2012)
Nature
, vol.486
, pp. 312-314
-
-
Hayden, E.C.1
-
152
-
-
84949444244
-
Reform of clinical research regulations, finally
-
Emanuel, E. J. Reform of clinical research regulations, finally. N. Engl. J. Med. 373, 2296-2299 (2015).
-
(2015)
N. Engl. J. Med
, vol.373
, pp. 2296-2299
-
-
Emanuel, E.J.1
-
153
-
-
84885127320
-
Ethical, legal, and social implications of incorporating genomic information into electronic health records
-
Hazin, R., et al. Ethical, legal, and social implications of incorporating genomic information into electronic health records. Genet. Med. 15, 810-816 (2013).
-
(2013)
Genet. Med
, vol.15
, pp. 810-816
-
-
Hazin, R.1
-
154
-
-
80053335117
-
Identifiability in biobanks: Models, measures, and mitigation strategies
-
Malin, B., Loukides, G., Benitez, K. & Clayton, E. Identifiability in biobanks: models, measures, and mitigation strategies. Hum. Genet. 130, 383-392 (2011).
-
(2011)
Hum. Genet
, vol.130
, pp. 383-392
-
-
Malin, B.1
Loukides, G.2
Benitez, K.3
Clayton, E.4
-
155
-
-
84872459720
-
Identifying personal genomes by surname inference
-
Gymrek, M., McGuire, A. L., Golan, D., Halperin, E. & Erlich, Y. Identifying personal genomes by surname inference. Science 339, 321-324.
-
Science
, vol.339
, pp. 321-324
-
-
Gymrek, M.1
McGuire, A.L.2
Golan, D.3
Halperin, E.4
Erlich, Y.5
-
156
-
-
84902271056
-
Return of genomic results to research participants: The floor, the ceiling, and the choices in between
-
Jarvik, G. P., et al. Return of genomic results to research participants: the floor, the ceiling, and the choices in between. Am. J. Hum. Genet. 94, 818-826 (2014).
-
(2014)
Am. J. Hum. Genet
, vol.94
, pp. 818-826
-
-
Jarvik, G.P.1
-
157
-
-
84859619831
-
Return of individual research results from genome-wide association studies: Experience of the Electronic Medical Records and Genomics (eMERGE) Network
-
Fullerton, S. M., et al. Return of individual research results from genome-wide association studies: experience of the Electronic Medical Records and Genomics (eMERGE) Network. Genet. Med. 14, 424-431 (2012).
-
(2012)
Genet. Med
, vol.14
, pp. 424-431
-
-
Fullerton, S.M.1
-
158
-
-
85031967310
-
Building an ontology of phentoypes for exsiting GWAS studies
-
Alipanah, N., Kim, H. & Ohno-Machado, L. Building an ontology of phentoypes for exsiting GWAS studies. AMIA Jt Summits. Transl. Sci. Proc. 2013, 4-8 (2013).
-
(2013)
AMIA Jt Summits. Transl. Sci. Proc
, vol.2013
, pp. 4-8
-
-
Alipanah, N.1
Kim, H.2
Ohno-Machado, L.3
-
159
-
-
85031964266
-
Learning phenotype mapping for integrating large genetic data
-
Hsu, C. N., et al. Learning phenotype mapping for integrating large genetic data. Proceedings of BioNLP 2011 Workshop [online], http: //www.aclweb.org/ anthology/W/W11/W11-0203.pdf (2011).
-
(2011)
Proceedings of BioNLP 2011 Workshop [Online]
-
-
Hsu, C.N.1
-
160
-
-
84891749517
-
The Human Phenotype Ontology project: Linking molecular biology and disease through phenotype data
-
Kohler, S., et al. The Human Phenotype Ontology project: linking molecular biology and disease through phenotype data. Nucleic Acids Res. 42, D966-D974 (2014).
-
(2014)
Nucleic Acids Res
, vol.42
, pp. D966-D974
-
-
Kohler, S.1
-
161
-
-
84937523757
-
The Human Phenotype Ontology: Semantic unification of common and rare disease
-
Groza, T., et al. The Human Phenotype Ontology: semantic unification of common and rare disease. Am. J. Hum. Genet. 97, 111-124 (2015).
-
(2015)
Am. J. Hum. Genet
, vol.97
, pp. 111-124
-
-
Groza, T.1
-
162
-
-
34748848639
-
The NCBI dbGaP database of genotypes and phenotypes
-
Mailman, M. D., et al. The NCBI dbGaP database of genotypes and phenotypes. Nat. Genet. 39, 1181-1186 (2007).
-
(2007)
Nat. Genet
, vol.39
, pp. 1181-1186
-
-
Mailman, M.D.1
-
163
-
-
84891750628
-
NCBI's Database of Genotypes and Phenotypes: DbGaP
-
Tryka, K. A., et al. NCBI's Database of Genotypes and Phenotypes: dbGaP. Nucleic Acids Res. 42, D975-D979 (2014).
-
(2014)
Nucleic Acids Res
, vol.42
, pp. D975-D979
-
-
Tryka, K.A.1
-
164
-
-
79960823864
-
The PhenX Toolki: Get the most from your measures
-
Hamilton, C. M., et al. The PhenX Toolki: get the most from your measures. Am. J. Epidemiol. 174, 253-260 (2011).
-
(2011)
Am. J. Epidemiol
, vol.174
, pp. 253-260
-
-
Hamilton, C.M.1
-
165
-
-
84864338647
-
Using PhenX measures to identify opportunities for cross-study analysis
-
Pan, H., et al. Using PhenX measures to identify opportunities for cross-study analysis. Hum. Mutat. 33, 849-857 (2012).
-
(2012)
Hum. Mutat
, vol.33
, pp. 849-857
-
-
Pan, H.1
-
166
-
-
84860473457
-
MultiPhen: Joint model of multiple phenotypes can increase discovery in GWAS
-
O'Reilly, P. F., et al. MultiPhen: joint model of multiple phenotypes can increase discovery in GWAS. PLoS ONE 7, e34861 (2012).
-
(2012)
PLoS ONE
, vol.7
, pp. e34861
-
-
O'Reilly, P.F.1
-
167
-
-
58049204427
-
A multivariate test of association
-
Ferreira, M. A. R. & Purcell, S. M. A multivariate test of association. Bioinformatics 25, 132-133 (2009).
-
(2009)
Bioinformatics
, vol.25
, pp. 132-133
-
-
Ferreira, M.A.R.1
Purcell, S.M.2
-
168
-
-
84879818733
-
A unified framework for association analysis with multiple related phenotypes
-
Stephens, M. A unified framework for association analysis with multiple related phenotypes. PLoS ONE 8, e65245 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e65245
-
-
Stephens, M.1
-
169
-
-
38149020685
-
Pleiotropy and principal components of heritability combine to increase power for association analysis
-
Klei, L., Luca, D., Devlin, B. & Roeder, K. Pleiotropy and principal components of heritability combine to increase power for association analysis. Genet. Epidemiol. 32, 9-19 (2008).
-
(2008)
Genet. Epidemiol
, vol.32
, pp. 9-19
-
-
Klei, L.1
Luca, D.2
Devlin, B.3
Roeder, K.4
-
170
-
-
84873489284
-
TATES: Efficient multivariate genotype-phenotype analysis for genome-wide association studies
-
Van Der Sluis, S., Posthuma, D. & Dolan, C. V. TATES: efficient multivariate genotype-phenotype analysis for genome-wide association studies. PLoS Genet. 9, e1003235 (2013).
-
(2013)
PLoS Genet
, vol.9
, pp. e1003235
-
-
Van Der Sluis, S.1
Posthuma, D.2
Dolan, C.V.3
-
171
-
-
84899768782
-
Comparison of multivariate genome-wide association methods
-
Galesloot, T. E., Van Steen, K., Kiemeney, L. A.L. M., Janss, L. L. & Vermeulen, S. H. A. Comparison of multivariate genome-wide association methods. PLoS ONE 9, e95923 (2014).
-
(2014)
PLoS ONE
, vol.9
, pp. e95923
-
-
Galesloot, T.E.1
Van Steen, K.2
Kiemeney, L.A.L.M.3
Janss, L.L.4
Vermeulen, S.H.A.5
-
172
-
-
66249095158
-
Bivariate association analyses for the mixture of continuous and binary traits with the use of extended generalized estimating equations
-
Liu, J., Pei, Y., Chris, J. & Deng, H. W. Bivariate association analyses for the mixture of continuous and binary traits with the use of extended generalized estimating equations. Genet. Epidemiol. 33, 217-227 (2009).
-
(2009)
Genet. Epidemiol
, vol.33
, pp. 217-227
-
-
Liu, J.1
Pei, Y.2
Chris, J.3
Deng, H.W.4
-
173
-
-
85031965943
-
The precision medicine initiative cohort program - Building a research foundation for 21st century medicine
-
Precision Medicine Initiative (PMI) Working Group
-
Precision Medicine Initiative (PMI) Working Group. The precision medicine initiative cohort program - building a research foundation for 21st century medicine. National Institutes of Health [online], http: //acd.od.nih.gov/reports/DRAFT-PMI-WG-Report-9-11-2015-508.pdf (2015).
-
(2015)
National Institutes of Health [Online]
-
-
-
174
-
-
84939140053
-
News from the NIH: Potential contributions of the behavioral and social sciences to the precision medicine initiative
-
Riley, W. T., Nilsen, W. J., Manolio, T. A., Masys, D. R. & Lauer, M. News from the NIH: potential contributions of the behavioral and social sciences to the precision medicine initiative. Transl. Behav. Med. 5, 243-246 (2015).
-
(2015)
Transl. Behav. Med
, Issue.5
, pp. 243-246
-
-
Riley, W.T.1
Nilsen, W.J.2
Manolio, T.A.3
Masys, D.R.4
Lauer, M.5
-
175
-
-
84859215798
-
What makes UK Biobank special?
-
Collins, R. What makes UK Biobank special?. Lancet 379, 1173-1174 (2012).
-
(2012)
Lancet
, vol.379
, pp. 1173-1174
-
-
Collins, R.1
-
176
-
-
84906250701
-
Emergeing progress in genomics - The first seven years
-
Crawford, D. C., et al. eMERGEing progress in genomics - The first seven years. Front. Genet. 5, 184 (2014).
-
(2014)
Front. Genet
, vol.5
, pp. 184
-
-
Crawford, D.C.1
-
177
-
-
84949426468
-
Bringing the Common Rule into the 21st Century
-
Hudson, K. L. & Collins, F. S. Bringing the Common Rule into the 21st Century. N. Engl. J. Med. 373, 2293-2296 (2015
-
(2015)
N. Engl. J. Med
, vol.373
, pp. 2293-2296
-
-
Hudson, K.L.1
Collins, F.S.2
|