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Volumn 186, Issue 3, 2010, Pages 767-773

One hundred years of pleiotropy: A retrospective

Author keywords

[No Author keywords available]

Indexed keywords

EVOLUTIONARY ADAPTATION; GENE LOCUS; GENE SEQUENCE; HUMAN; MEDICAL GENETICS; MOLECULAR GENETICS; PHENOTYPE; PLEIOTROPY; PRIORITY JOURNAL; REVIEW; RNA SPLICING;

EID: 78951491095     PISSN: 00166731     EISSN: 00166731     Source Type: Journal    
DOI: 10.1534/genetics.110.122549     Document Type: Review
Times cited : (321)

References (63)
  • 1
    • 0017298367 scopus 로고
    • Overlapping genes in bacteriophage φX174
    • BARRELL, B. G., G. M. AIR and C. A. HUTCHISON, 1976 Overlapping genes in bacteriophage φX174. Nature 264: 34-41.
    • (1976) Nature , vol.264 , pp. 34-41
    • Barrell, B.G.1    Air, G.M.2    Hutchison, C.A.3
  • 2
    • 0001194208 scopus 로고
    • Genetic control of biochemical reactions in Neurospora
    • BEADLE, G. W., and E. L. TATUM, 1941 Genetic control of biochemical reactions in Neurospora. Proc. Natl. Acad. Sci. USA 27: 499-506.
    • (1941) Proc. Natl. Acad. Sci. USA , vol.27 , pp. 499-506
    • Beadle, G.W.1    Tatum, E.L.2
  • 3
    • 0000028591 scopus 로고
    • Neurospora. 2. Methods of producing and detecting mutations concerned with nutritional requirements
    • BEADLE, G. W., and E. L. TATUM, 1945 Neurospora. 2. Methods of producing and detecting mutations concerned with nutritional requirements. Am. J. Bot. 32: 678-686.
    • (1945) Am. J. Bot. , vol.32 , pp. 678-686
    • Beadle, G.W.1    Tatum, E.L.2
  • 4
    • 0022552305 scopus 로고
    • Major transcript of the frameshifted coxII gene from trypanosome mitochondria contains four nucleotides that are not encoded in the DNA
    • BENNE, R., J. VAN DEN BURG, J. P. BRAKENHOFF, P. SLOOF, J. H. VAN BOOM et al., 1986 Major transcript of the frameshifted coxII gene from trypanosome mitochondria contains four nucleotides that are not encoded in the DNA. Cell 46: 819-826.
    • (1986) Cell , vol.46 , pp. 819-826
    • Benne, R.1    Van Den Burg, J.2    Brakenhoff, J.P.3    Sloof, P.4    Van Boom, J.H.5
  • 5
    • 0344622123 scopus 로고
    • Spliced segments at 59 terminus of adenovirus 2 late messenger RNA
    • BERGET, S. M., C. MOORE and P. A. SHARP, 1977 Spliced segments at 59 terminus of adenovirus 2 late messenger RNA. Proc. Natl. Acad. Sci. USA 74: 3171-3175.
    • (1977) Proc. Natl. Acad. Sci. USA , vol.74 , pp. 3171-3175
    • Berget, S.M.1    Moore, C.2    Sharp, P.A.3
  • 6
    • 0013394889 scopus 로고    scopus 로고
    • Mechanisms of alternative pre-messenger RNA splicing
    • BLACK, D. L., 2003 Mechanisms of alternative pre-messenger RNA splicing. Annu. Rev. Biochem. 72: 291-336.
    • (2003) Annu. Rev. Biochem. , vol.72 , pp. 291-336
    • Black, D.L.1
  • 7
    • 33344459577 scopus 로고    scopus 로고
    • Pleiotropic effects of the duplicate maize FLORICAULA/LEAFY genes zfl1 and zfl2 on traits under selection during maize domestication
    • BOMBLIES, K., and J. F. DOEBLEY, 2006 Pleiotropic effects of the duplicate maize FLORICAULA/LEAFY genes zfl1 and zfl2 on traits under selection during maize domestication. Genetics 172: 519-531.
    • (2006) Genetics , vol.172 , pp. 519-531
    • Bomblies, K.1    Doebley, J.F.2
  • 8
    • 33646204592 scopus 로고    scopus 로고
    • Phenotypic variation and natural selection at Catsup, a pleiotropic quantitative trait gene in Drosophila
    • CARBONE, M. A., K. W. JORDAN, R. F. LYMAN, S. T. HARBISON, J. LEIPS et al., 2006 Phenotypic variation and natural selection at Catsup, a pleiotropic quantitative trait gene in Drosophila. Curr. Biol. 16: 912-919.
    • (2006) Curr. Biol. , vol.16 , pp. 912-919
    • Carbone, M.A.1    Jordan, K.W.2    Lyman, R.F.3    Harbison, S.T.4    Leips, J.5
  • 9
    • 0002969055 scopus 로고
    • Pleiotropic gene action
    • CASPARI, E., 1952 Pleiotropic gene action. Evolution 6: 1-18.
    • (1952) Evolution , vol.6 , pp. 1-18
    • Caspari, E.1
  • 10
    • 33746158977 scopus 로고    scopus 로고
    • Developmental integration and the evolution of pleiotropy
    • CHEVERUD, J. M., 1996 Developmental integration and the evolution of pleiotropy. Am. Zool. 36: 44-50.
    • (1996) Am. Zool. , vol.36 , pp. 44-50
    • Cheverud, J.M.1
  • 12
    • 0019785870 scopus 로고
    • Human growth hormone DNA sequence and mRNA structure: Possible alternative splicing
    • DENOTO, F. M., D. D. MOORE and H. M. GOODMAN, 1981 Human growth hormone DNA sequence and mRNA structure: possible alternative splicing. Nucleic Acids Res. 9: 3719-3730.
    • (1981) Nucleic Acids Res. , vol.9 , pp. 3719-3730
    • Denoto, F.M.1    Moore, D.D.2    Goodman, H.M.3
  • 13
    • 49649114289 scopus 로고    scopus 로고
    • Escape from adaptive conflict after duplication in an anthocyanin pathway gene
    • DES MARAIS, D. L., and M. D. RAUSHER, 2008 Escape from adaptive conflict after duplication in an anthocyanin pathway gene. Nature 454: 762-766.
    • (2008) Nature , vol.454 , pp. 762-766
    • Des Marais, D.L.1    Rausher, M.D.2
  • 15
    • 0036006175 scopus 로고    scopus 로고
    • Wrestling with pleiotropy: Genomic and topological analysis of the yeast gene expression network
    • FEATHERSTONE, D. E., and K. BROADIE, 2002 Wrestling with pleiotropy: genomic and topological analysis of the yeast gene expression network. BioEssays 24: 267-274.
    • (2002) BioEssays , vol.24 , pp. 267-274
    • Featherstone, D.E.1    Broadie, K.2
  • 17
    • 66049159816 scopus 로고    scopus 로고
    • Genetic architecture of quantitative traits in mice, flies, and humans
    • FLINT, J., and T. F. C. MACKAY, 2009 Genetic architecture of quantitative traits in mice, flies, and humans. Genome Res. 19: 723-733.
    • (2009) Genome Res. , vol.19 , pp. 723-733
    • Flint, J.1    Mackay, T.F.C.2
  • 18
    • 0016442397 scopus 로고
    • Reovirus messenger RNA contains a methylated, blocked 5′-terminal structure: M7g(5′)Ppp(5′)Gmpcp
    • FURUICHI, Y., M. MORGAN, S. MUTHUKRISHNAN and A. J. SHATKIN, 1975 Reovirus messenger RNA contains a methylated, blocked 5′-terminal structure: M7g(5′)Ppp(5′)Gmpcp. Proc. Natl. Acad. Sci. USA 72: 362-366.
    • (1975) Proc. Natl. Acad. Sci. USA , vol.72 , pp. 362-366
    • Furuichi, Y.1    Morgan, M.2    Muthukrishnan, S.3    Shatkin, A.J.4
  • 19
    • 85180042417 scopus 로고
    • University of California Press, Berkeley, CA
    • GOLDSCHMIDT, R. B., 1955 Theoretical Genetics. University of California Press, Berkeley, CA.
    • (1955) Theoretical Genetics
    • Goldschmidt, R.B.1
  • 20
    • 70349524975 scopus 로고    scopus 로고
    • RNA editing: A driving force for adaptive evolution?
    • GOMMANS, W. M., S. P. MULLEN and S. MAAS, 2009 RNA editing: A driving force for adaptive evolution? BioEssays 31: 1137-1145.
    • (2009) BioEssays , vol.31 , pp. 1137-1145
    • Gommans, W.M.1    Mullen, S.P.2    Maas, S.3
  • 21
    • 0038736116 scopus 로고
    • An analysis of the "pleiotropic" effects of a new lethal mutation in the rat (Mus norvegicus)
    • GRUNEBERG, H., 1938 An analysis of the "pleiotropic" effects of a new lethal mutation in the rat (Mus norvegicus). Proc. R. Soc. Lond. B 125: 123-144.
    • (1938) Proc. R. Soc. Lond. B , vol.125 , pp. 123-144
    • Gruneberg, H.1
  • 24
    • 78951470852 scopus 로고
    • Objectives and findings of phenogenetics
    • in German
    • HAECKER, V., 1925 Objectives and findings of phenogenetics. Bibliographia Genetica 1: 1-314 (in German).
    • (1925) Bibliographia Genetica , vol.1 , pp. 1-314
    • Haecker, V.1
  • 25
    • 0035974843 scopus 로고    scopus 로고
    • Genetic linkage of ecological specialization and reproductive isolation in pea aphids
    • HAWTHORNE, D. J., and S. VIA, 2001 Genetic linkage of ecological specialization and reproductive isolation in pea aphids. Nature 412: 904-907.
    • (2001) Nature , vol.412 , pp. 904-907
    • Hawthorne, D.J.1    Via, S.2
  • 26
    • 33747817940 scopus 로고    scopus 로고
    • Toward a molecular understanding of pleiotropy
    • HE, X. L., and J. Z. ZHANG, 2006 Toward a molecular understanding of pleiotropy. Genetics 173: 1885-1891.
    • (2006) Genetics , vol.173 , pp. 1885-1891
    • He, X.L.1    Zhang, J.Z.2
  • 27
    • 0037356334 scopus 로고    scopus 로고
    • The centenary of the one-gene one-enzyme hypothesis
    • HICKMAN, M., and J. CAIRNS, 2003 The centenary of the one-gene one-enzyme hypothesis. Genetics 163: 839-841.
    • (2003) Genetics , vol.163 , pp. 839-841
    • Hickman, M.1    Cairns, J.2
  • 28
    • 0031800626 scopus 로고    scopus 로고
    • Seven types of pleiotropy
    • HODGKIN, J., 1998 Seven types of pleiotropy. Int. J. Dev. Biol. 42: 501-505.
    • (1998) Int. J. Dev. Biol. , vol.42 , pp. 501-505
    • Hodgkin, J.1
  • 29
    • 0029297969 scopus 로고
    • One-gene one-enzyme: Remembering biochemical genetics
    • HOROWITZ, N. H., 1995 One-gene one-enzyme: remembering biochemical genetics. Protein Sci. 4: 1017-1019.
    • (1995) Protein Sci. , vol.4 , pp. 1017-1019
    • Horowitz, N.H.1
  • 30
    • 77950369259 scopus 로고    scopus 로고
    • Moonlighting proteins: An intriguing mode of multitasking
    • HUBERTS, D. H. E. W., and I. J. VAN DER KLEI, 2010 Moonlighting proteins: an intriguing mode of multitasking. Biochim. Biophys. Acta 1803: 520-525.
    • (2010) Biochim. Biophys. Acta , vol.1803 , pp. 520-525
    • Huberts, D.H.E.W.1    Van Der Klei, I.J.2
  • 31
    • 37649004960 scopus 로고    scopus 로고
    • Genetic variation in the cysteine biosynthesis pathway causes sensitivity to pharmacological compounds
    • KIM, H. S., and J. C. FAY, 2007 Genetic variation in the cysteine biosynthesis pathway causes sensitivity to pharmacological compounds. Proc. Natl. Acad. Sci. USA 104: 19387-19391.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 19387-19391
    • Kim, H.S.1    Fay, J.C.2
  • 32
    • 33748335479 scopus 로고    scopus 로고
    • Unraveling adaptive evolution: How a single point mutation affects the protein coregulation network
    • KNIGHT, C. G., N. ZITZMANN, S. PRABHAKAR, R. ANTROBUS, R. DWEK et al., 2006 Unraveling adaptive evolution: how a single point mutation affects the protein coregulation network. Nat. Genet. 38: 1015-1022.
    • (2006) Nat. Genet. , vol.38 , pp. 1015-1022
    • Knight, C.G.1    Zitzmann, N.2    Prabhakar, S.3    Antrobus, R.4    Dwek, R.5
  • 33
    • 68149142377 scopus 로고    scopus 로고
    • Natural selection on pleiotropic quantitative trait loci affecting a life-history trade-off in Avena Barbata
    • LATTA, R. G., and K. M. GARDNER, 2009 Natural selection on pleiotropic quantitative trait loci affecting a life-history trade-off in Avena Barbata. Evolution 63: 2153-2163.
    • (2009) Evolution , vol.63 , pp. 2153-2163
    • Latta, R.G.1    Gardner, K.M.2
  • 34
    • 33645794912 scopus 로고    scopus 로고
    • The forgotten "Old-Darwinian" synthesis: The evolutionary theory of Ludwig H. Plate (1862-1937)
    • LEVIT, G. S., and U.HOSSFELD, 2006 The forgotten "Old- Darwinian" synthesis: the evolutionary theory of Ludwig H. Plate (1862-1937). N.T.M. 14: 9-25.
    • (2006) N.T.M. , vol.14 , pp. 9-25
    • Levit, G.S.1    Hossfeld, U.2
  • 37
    • 33750330814 scopus 로고    scopus 로고
    • Of flies and man: Drosophila as a model for human complex traits
    • MACKAY, T. F. C., and R. R. H. ANHOLT, 2006 Of flies and man: Drosophila as a model for human complex traits. Annu. Rev. Genomics Hum. Genet. 7: 339-367.
    • (2006) Annu. Rev. Genomics Hum. Genet. , vol.7 , pp. 339-367
    • Mackay, T.F.C.1    Anholt, R.R.H.2
  • 38
    • 2542635754 scopus 로고    scopus 로고
    • The evolution of a pleiotropic fitness tradeoff in Pseudomonas fluorescens
    • MACLEAN, R. C., G. BELL and P. B. RAINEY, 2004 The evolution of a pleiotropic fitness tradeoff in Pseudomonas fluorescens. Proc. Natl. Acad. Sci. USA 101: 8072-8077.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 8072-8077
    • Maclean, R.C.1    Bell, G.2    Rainey, P.B.3
  • 39
    • 33748607688 scopus 로고    scopus 로고
    • Breaking the central dogma by RNA editing
    • MAYDANOVYCH, O., and P. A. BEAL, 2006 Breaking the central dogma by RNA editing. Chem. Rev. 106: 3397-3411.
    • (2006) Chem. Rev. , vol.106 , pp. 3397-3411
    • Maydanovych, O.1    Beal, P.A.2
  • 40
    • 0000561181 scopus 로고
    • Sympatric speciation
    • MAYNARD SMITH, J., 1966 Sympatric speciation. Am. Nat. 100: 637.
    • (1966) Am. Nat. , vol.100 , pp. 637
    • Maynard Smith, J.1
  • 41
    • 0003401433 scopus 로고
    • The Bellknap Press of Harvard University Press, Cambridge, MA
    • MAYR, E., 1963 Animal Species and Evolution. The Bellknap Press of Harvard University Press, Cambridge, MA.
    • (1963) Animal Species and Evolution
    • Mayr, E.1
  • 45
    • 66749185404 scopus 로고    scopus 로고
    • What can genetic variation tell us about the evolution of senescence?
    • MOORAD, J. A., and D. E. L. PROMISLOW, 2009 What can genetic variation tell us about the evolution of senescence? Proc. R. Soc. B Biol. Sci. 276: 2271-2278.
    • (2009) Proc. R. Soc. B Biol. Sci. , vol.276 , pp. 2271-2278
    • Moorad, J.A.1    Promislow, D.E.L.2
  • 46
    • 0034025692 scopus 로고    scopus 로고
    • Adaptation and the cost of complexity
    • ORR, H. A., 2000 Adaptation and the cost of complexity. Evolution 54: 13-20.
    • (2000) Evolution , vol.54 , pp. 13-20
    • Orr, H.A.1
  • 48
    • 0024435352 scopus 로고
    • Pleiotropy revisited: Molecular explanations of a classic concept
    • PYERITZ, R. E., 1989 Pleiotropy revisited: molecular explanations of a classic concept. Am. J. Med. Genet. 34: 124-134.
    • (1989) Am. J. Med. Genet. , vol.34 , pp. 124-134
    • Pyeritz, R.E.1
  • 49
    • 34250813107 scopus 로고    scopus 로고
    • Alternative splicing of pre-messenger RNAs in plants in the genomic era
    • REDDY, A. S. N., 2007 Alternative splicing of pre-messenger RNAs in plants in the genomic era. Annu. Rev. Plant Biol. 58: 267-294.
    • (2007) Annu. Rev. Plant Biol. , vol.58 , pp. 267-294
    • Reddy, A.S.N.1
  • 50
    • 34748889509 scopus 로고    scopus 로고
    • Molecular ecology of global change
    • REUSCH, T. B. H., and T. E. WOOD, 2007 Molecular ecology of global change. Mol. Ecol. 16: 3973-3992.
    • (2007) Mol. Ecol. , vol.16 , pp. 3973-3992
    • Reusch, T.B.H.1    Wood, T.E.2
  • 51
  • 52
    • 72249102481 scopus 로고    scopus 로고
    • A preliminary analysis of gene pleiotropy estimated from protein sequences
    • SU, Z., Y. ZENG and X. GU, 2009 A preliminary analysis of gene pleiotropy estimated from protein sequences. J.Exp. Zool. 312B: 1-10.
    • (2009) J.Exp. Zool. , vol.312 B , pp. 1-10
    • Su, Z.1    Zeng, Y.2    Gu, X.3
  • 53
    • 0001925618 scopus 로고
    • Sympatric speciation in insects: Perceptions and perspective
    • edited by D. OTTE and J. A. ENDLER. Sinauer Associates, Sunderland, MA
    • TAUBER, C. A., and M. J. TAUBER, 1989 Sympatric speciation in insects: perceptions and perspective, pp. 307-344 in Speciation and Its Consequences, edited by D. OTTE and J. A. ENDLER. Sinauer Associates, Sunderland, MA.
    • (1989) Speciation and Its Consequences , pp. 307-344
    • Tauber, C.A.1    Tauber, M.J.2
  • 54
    • 41349102014 scopus 로고    scopus 로고
    • Pleiotropic scaling of gene effects and the 'cost of complexity'
    • WAGNER, G. P., J. P. KENNEY-HUNT, M.PAVLICEV, J. R. PECK, D.WAXMAN et al., 2008 Pleiotropic scaling of gene effects and the 'cost of complexity'. Nature 452: 470-472.
    • (2008) Nature , vol.452 , pp. 470-472
    • Wagner, G.P.1    Kenney-Hunt, J.P.2    Pavlicev, M.3    Peck, J.R.4    Waxman, D.5
  • 55
    • 0032549157 scopus 로고    scopus 로고
    • Pleiotropy and the preservation of perfection
    • WAXMAN, D., and J. R. PECK, 1998 Pleiotropy and the preservation of perfection. Science 279: 1210-1213.
    • (1998) Science , vol.279 , pp. 1210-1213
    • Waxman, D.1    Peck, J.R.2
  • 56
    • 0017401131 scopus 로고
    • Definition of a large viral transcription unit late in Ad2 infection of HeLa-cells: Mapping of nascent RNA molecules labeled in isolated nuclei
    • WEBER, J., W. JELINEK and J. E. DARNELL, 1977 Definition of a large viral transcription unit late in Ad2 infection of HeLa-cells: mapping of nascent RNA molecules labeled in isolated nuclei. Cell 10: 611-616.
    • (1977) Cell , vol.10 , pp. 611-616
    • Weber, J.1    Jelinek, W.2    Darnell, J.E.3
  • 57
    • 0019375163 scopus 로고
    • Osteogenesis imperfecta: Historical background
    • WEIL, U. H., 1981 Osteogenesis imperfecta: historical background. Clin. Orthop. Relat. Res. 6-10.
    • (1981) Clin. Orthop. Relat. Res. , pp. 6-10
    • Weil, U.H.1
  • 58
    • 0043286749 scopus 로고    scopus 로고
    • Modularity and the cost of complexity
    • WELCH, J. J., and D. WAXMAN, 2003 Modularity and the cost of complexity. Evolution 57: 1723-1734.
    • (2003) Evolution , vol.57 , pp. 1723-1734
    • Welch, J.J.1    Waxman, D.2
  • 60
    • 73949106868 scopus 로고    scopus 로고
    • Antagonistic coevolution of two imprinted loci with pleiotropic effects
    • WILKINS, J. F., 2010 Antagonistic coevolution of two imprinted loci with pleiotropic effects. Evolution 64: 142-151.
    • (2010) Evolution , vol.64 , pp. 142-151
    • Wilkins, J.F.1
  • 61
    • 0000055057 scopus 로고
    • Pleiotropy, natural selection, and the evolution of senescence
    • WILLIAMS, G. C., 1957 Pleiotropy, natural selection, and the evolution of senescence. Evolution 11: 398-411.
    • (1957) Evolution , vol.11 , pp. 398-411
    • Williams, G.C.1
  • 63
    • 0033152519 scopus 로고    scopus 로고
    • The evolutionary genetics of ageing and longevity
    • ZWAAN, B. J., 1999 The evolutionary genetics of ageing and longevity. Heredity 82: 589-597.
    • (1999) Heredity , vol.82 , pp. 589-597
    • Zwaan, B.J.1


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