Enhancing the Power of Genetic Association Studies through the Use of Silver Standard Cases Derived from Electronic Medical Records

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  McDavid, Andrew ^a   Crane, Paul K ^b   Newton, Katherine M ^c   Crosslin, David R ^d   McCormick, Wayne ^b   Weston, Noah ^c   Ehrlich, Kelly ^c   Hart, Eugene ^c   Harrison, Robert ^c   Kukull, Walter A ^d   Rottscheit, Carla ^e   Peissig, Peggy ^e   Stefanski, Elisha ^e   McCarty, Catherine A ^f   Zuvich, Rebecca Lynn ^g   Ritchie, Marylyn D ^h   Haines, Jonathan L ^g   Denny, Joshua C ⁱ   Schellenberg, Gerard D ^j   de Andrade, Mariza ^k   Kullo, Iftikhar ^l   Li, Rongling ^m   Mirel, Daniel ⁿ   Crenshaw, Andrew ⁿ   Bowen, James D ^o   Li, Ge ^b   Tsuang, Debby ^b,p   McCurry, Susan ^d   Teri, Linda ^d   Larson, Eric B ^b,c   Jarvik, Gail P ^b   Carlson, Chris S ^a   more..

^a Fred Hutchinson Cancer Research Center   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c GROUP HEALTH RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

^e MARSHFIELD CLINIC   (United States)

^f ESSENTIA INSTITUTE OF RURAL HEALTH   (United States)

^g VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^h PENNSYLVANIA STATE UNIVERSITY   (United States)

ⁱ VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^j UNIVERSITY OF PENNSYLVANIA   (United States)

^k Mayo Clinic   (United States)

^l MAYO CLINIC   (United States)

^m NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

ⁿ BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^o SWEDISH MEDICAL CENTER   (United States)

^p VA PUGET SOUND HEALTH CARE SYSTEM   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ALZHEIMER DISEASE; ANALYTICAL ERROR; ARTICLE; CONTROLLED STUDY; DATA ANALYSIS; ELECTRONIC MEDICAL RECORD; FEASIBILITY STUDY; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC IDENTIFICATION; GENETIC MODEL; GENETIC RISK; GENOTYPE; GOLD STANDARD; HETEROZYGOTE; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MATHEMATICAL MODEL; PHENOTYPE; SILVER STANDARD; SINGLE NUCLEOTIDE POLYMORPHISM; STANDARD; VALIDATION PROCESS;

AGED; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; COMPUTER SIMULATION; DEMENTIA; ELECTRONIC HEALTH RECORDS; GENOME-WIDE ASSOCIATION STUDY; GENOMICS; HUMANS; MODELS, STATISTICAL; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 84878832780     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0063481     Document Type: Article

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