Volumn 518, Issue 7538, 2015, Pages 197-206
Genetic studies of body mass index yield new insights for obesity biology
(1,405)
Locke, A E
a
Kahali, B
a
Berndt, S I
a
Justice, A E
a
Pers, T H
a
Day, F R
a
Powell, C
a
Vedantam, S
a
Buchkovich, M L
a
Yang, J
a
Croteau Chonka, D C
a
Esko, T
a
Fall, T
a
Ferreira, T
a
Gustafsson, S
a
Kutalik, Z
a
Luan, J
a
Magi R
a
Randall, J C
a
Winkler, T W
a
Wood, A R
a
Workalemahu, T
a
Faul, J D
a
Smith, J A
a
Zhao, J H
a
Zhao, W
a
Chen, J
a
Fehrmann, R
a
Hedman, A K
a
Karjalainen, J
a
Schmidt, E M
a
Absher, D
a
Amin, N
a
Anderson, D
a
Beekman, M
a
Bolton, J L
a
Bragg Gresham, J L
a
Buyske, S
a
Demirkan, A
a
Deng, G
a
Ehret, G
a
Feenstra, B
a
Feitosa, M
a
Fischer, K
a
Goel, A
a
Gong, J
a
Jackson, A U
a
Kanoni, S
a
Kleber, M E
a
Kristiansson, K
a
Lim, U
a
Lotay, V
a
Mangino, M
a
Leach, I M
a
Medina Gomez, C
a
Medland, S E
a
Nalls, M A
a
Palmer, C D
a
Pasko, D
a
Pechlivanis, S
a
Peters, M J
a
Prokopenko, I
a
Shungin, D
a
Stancakova A
a
Strawbridge, R J
a
Sung, Y J
a
Tanaka, T
a
Teumer, A
a
Trompet, S
a
van der Laan, S W
a
van Setten, J
a
Van Vliet Ostaptchouk, J V
a
Wang, Z
a
Yengo, L
a
Zhang, W
a
Isaacs, A
a
Albrecht, E
a
Arnlov J
a
Arscott, G M
a
Attwood, A P
a
Bandinelli, S
a
Barrett, A
a
Bas, I N
a
Bellis, C
a
Bennett, A J
a
Berne, C
a
Blagieva, R
a
Bluher M
a
Bohringer S
a
Bonnycastle, L L
a
Bottcher Y
a
Boyd, H A
a
Bruinenberg, M
a
Caspersen, I H
a
Chen, Y I
a
Clarke, R
a
Daw, E W
a
de Craen, A J M
a
Delgado, G
a
Dimitriou, M
a
Doney, A S F
a
Eklund, N
a
Estrada, K
a
Eury, E
a
Folkersen, L
a
Fraser, R M
a
Garcia, M
a
Geller, F
a
Giedraitis, V
a
Gigante, B
a
Go, A S
a
Golay, A
a
Goodall, A
a
Gordon, S D
a
Gorski, M
a
Grabe, H J
a
Grallert, H
a
Grammer, T B
a
Grassler J
a
Gronberg H
a
Groves, C J
a
Gusto, G
a
Haessler, J
a
Hall, P
a
Haller, T
a
Hallmans, G
a
Hartman, C A
a
Hassinen, M
a
Hayward, C
a
Heard Costa, N L
a
Helmer, Q
a
Hengstenberg, C
a
Holmen, O
a
Hottenga, J J
a
James, A L
a
Jeff, J
a
Johansson, A
a
Jolley, J
a
Juliusdottir, T
a
Kinnunen, L
a
Koenig, W
a
Koskenvuo, M
a
Kratzer, W
a
Laitinen, J
a
Lamina, C
a
Leander, K
a
Lee, N R
a
Lichtner, P
a
Lind, L
a
Lindstrom J
a
Lo, K S
a
Lobbens, S
a
Lorbeer, R
a
Lu, Y
a
Mach, F
a
Magnusson, P K
a
Mahajan, A
a
McArdle, W L
a
McLachlan, S
a
Menni, C
a
Merger, S
a
Mihailov, E
a
Milani, L
a
Moayyeri, A
a
Monda, K L
a
Morken, M A
a
Mulas, A
a
Muller G
a
Muller Nurasyid M
a
Musk, A W
a
Nagaraja, R
a
Nothen M M
a
Nolte, I M
a
Pilz, S
a
Rayner, N W
a
Renstrom, F
a
Rettig, R
a
Ried, J S
a
Ripke, S
a
Robertson, N
a
Rose, L M
a
Sanna, S
a
Scharnagl, H
a
Scholtens, S
a
Schumacher, F
a
Scott, W R
a
Seufferlein, T
a
Shi, J
a
Smith, A V
a
Smolonska, J
a
Stanton, A V
a
Steinthorsdottir, V
a
Stirrups, K
a
Stringham, H M
a
Sundstrom J
a
Swertz, M A
a
Swift, A J
a
Syvanen A C
a
Tan, S T
a
Tayo, B
a
Thorand, B
a
Thorleifsson, G
a
Tyrer, J
a
Uh, H W
a
Vandenput, L
a
Verhulst, F C
a
Vermeulen, S H
a
Verweij, N
a
Vonk, J M
a
Waite, L L
a
Warren, H R
a
Waterworth, D M
a
Weedon, M N
a
Wilkens, L
a
Willenborg, C
a
Wilsgaard, T
a
Wojczynski, M K
a
Wong, A
a
Wright, A F
a
Zhang, Q
a
Brennan, E P
a
Choi, M
a
Dastani, Z
a
Drong, A W
a
Eriksson, P
a
Franco Cereceda, A
a
Gadin J R
a
Gharavi, A G
a
Goddard, M E
a
Handsaker, R E
a
Huang, J
a
Karpe, F
a
Kathiresan, S
a
Keildson, S
a
Kiryluk, K
a
Kubo, M
a
Lee, J Y
a
Liang, L
a
Lifton, R P
a
Ma, B
a
McCarroll, S A
a
McKnight, A J
a
Min, J L
a
Moffatt, M F
a
Montgomery, G W
a
Murabito, J M
a
Nicholson, G
a
Nyholt, D R
a
Okada, Y
a
Perry, J R
a
Dorajoo, R
a
Reinmaa, E
a
Salem, R M
a
Sandholm, N
a
Scott, R A
a
Stolk, L
a
Takahashi, A
a
Van't Hooft, F M
a
Vinkhuyzen, A A E
a
Westra, H J
a
Zheng, W
a
Zondervan, K T
a
Heath, A C
a
Arveiler, D
a
Bakker, S J
a
Beilby, J P
a
Bergman, R N
a
Blangero, J
a
Bovet, P
a
Campbell, H
a
Caulfield, M
a
Cesana, G
a
Chakravarti, A
a
Chasman, D
a
Chines, P S
a
Collins, F S
a
Crawford, D
a
Cupples, L A
a
Cusi, D
a
Danesh, J
a
de Faire, U
a
Den Ruijter, H M
a
Dominiczak, A F
a
Erbel, R
a
Erdmann, J
a
Eriksson, J G
a
Farrall, M
a
Felix, S B
a
Ferrannini, E
a
Ferrieres J
a
Ford, I
a
Forouhi, N G
a
Forrester, T
a
Franco, O H
a
Gansevoort, R T
a
Gejman, P V
a
Gieger, C
a
Gottesman, O
a
Gudnason, V
a
Gyllensten, U B
a
Hall, A S
a
Harris, T B
a
Hattersley, A T
a
Hicks, A A
a
Hindorff, L
a
Hingorani, A
a
Hofman, A
a
Homuth, G
a
Hovingh, G
a
Humphries, S E
a
Hunt, S C
a
Hypponen E
a
Illig, T
a
Jacobs, K B
a
Jarvelin, M R
a
Jockel K H
a
Johansen, B
a
Jousilahti, P
a
Jukema, J
a
Jula, A
a
Kaprio, J
a
Kastelein, J J
a
Keinanen Kiukaanniemi, S M
a
Kiemeney, L A
a
Knekt, P
a
Kooner, J S
a
Kooperberg, C
a
Kovacs, P
a
Kraja, A T
a
Kumari, M
a
Kuusisto, J
a
Lakka, T
a
Langenberg, C
a
Le Marchand, L
a
Lehtimaki T
a
Lyssenko, V
a
Mannisto S
a
Marette, A
a
Matise, T
a
McKenzie, C A
a
McKnight, B
a
Moll, F L
a
Morris, A D
a
Morris, A P
a
Murray, J C
a
Nelis, M
a
Ohlsson, C
a
Oldehinkel, A J
a
Ong, K K
a
Madden, P A F
a
Pasterkamp, G
a
Peden, J F
a
Peters, A
a
Postma, D S
a
Pramstaller, P P
a
Price, J F
a
Qi, L
a
Raitakari, O
a
Rankinen, T
a
Rao, D C
a
Rice, T K
a
Ridker, P
a
Rioux, J D
a
Ritchie, M
a
Rudan, I
a
Salomaa, V
a
Samani, N
a
Saramies, J
a
Sarzynski, M A
a
Schunkert, H
a
Schwarz, P E
a
Sever, P
a
Shuldiner, A R
a
Sinisalo, J
a
Stolk, R P
a
Strauch, K
a
Tonjes A
a
Tregouet D A
a
Tremblay, A
a
Tremoli, E
a
Virtamo, J
a
Vohl, M C
a
Volker U
a
Waeber, G
a
Willemsen, G
a
Witteman, J C
a
Zillikens, M C
a
Adair, L S
a
Amouyel, P
a
Asselbergs, F W
a
Assimes, T L
a
Bochud, M
a
Boehm, B O
a
Boerwinkle, E
a
Bornstein, S R
a
Bottinger, E P
a
Bouchard, C
a
Cauchi, S
a
Chambers, J C
a
Chanock, S J
a
Cooper, R S
a
de Bakker, P I W
a
Dedoussis, G V
a
Ferrucci, L
a
Franks, P W
a
Froguel, P
a
Groop, L
a
Haiman, C
a
Hamsten, A
a
Hui, J
a
Hunter, D J
a
Hveem, K
a
Kaplan, R C
a
Kivimaki, M
a
Kuh, D
a
Laakso, M
a
Liu, Y
a
Martin, N G
a
Marz W
a
Melbye, M
a
Metspalu, A
a
Moebus, S
a
Munroe, P
a
Njolstad I
a
Oostra, B A
a
Palmer, C N
a
Pedersen, N L
a
Perola, M
a
Perusse L
a
Peters, U
a
Power, C
a
Quertermous, T
a
Rauramaa, R
a
Rivadeneira, F
a
Saaristo, T E
a
Saleheen, D
a
Sattar, N
a
Schadt, E
a
Schlessinger, D
a
Slagboom, P E
a
Snieder, H
a
Spector, T D
a
Thorsteinsdottir, U
a
Stumvoll, M
a
Tuomilehto, J
a
Uitterlinden, A G
a
Uusitupa, M
a
van der Harst, P
a
Walker, M C
a
Wallaschofski, H
a
Wareham, N
a
Watkins, H
a
Weir, D R
a
Wichmann, H
a
Wilson, J F
a
Zanen, P
a
Borecki, I
a
Deloukas, P
a
Fox, C S
a
Heid, I M
a
O'connell, J R
a
Strachan, D P
a
Stefansson, K
a
Van Duijn, C
a
Abecasis, G
a
Franke, L
a
Frayling, T M
a
McCarthy, M I
a
Visscher, P M
a
Scherag, A
a
Willer, C J
a
Boehnke, M
a
Mohlke, K L
a
Lindgren, C M
a
Beckmann, J S
a
Barroso, I
a
North, K E
a
Ingelsson, E
a
Hirschhorn, J N
a
Loos, R J
a
Speliotes, E K
a
Thompson, J R
a
Goldstein, B A
a
Konig I R
a
Cazier, J B
a
Grundberg, E
a
Havulinna, A S
a
Ho, W K
a
Hopewell, J C
a
Eriksson, N
a
Lundmark, P
a
Lyytikainen L P
a
Rafelt, S
a
Tikkanen, E
a
Van Zuydam, N
a
Voight, B F
a
Ziegler, A
a
Altshuler, D
a
Balmforth, A J
a
Braund, P S
a
Burgdorf, C
a
Claudi Boehm, S
a
Cox, D
a
Do, R
a
Doney, A S
a
El Mokhtari, N
a
Fontanillas, P
a
Hager, J
a
Han, B G
a
Hunt, S E
a
Kang, H M
a
Kessler, T
a
Knowles, J W
a
Kolovou, G
a
Langford, C
a
Lokki, M L
a
Lundmark, A
a
Meisinger, C
a
Melander, O
a
Maouche, S
a
Nikus, K
a
Rasheed, A
a
Rosinger, S
a
Rubin, D
a
Rumpf, M P
a
Schafer A
a
Sivananthan, M
a
Song, C
a
Stewart, A F
a
Thorgeirsson, G
a
van der Schoot, C E
a
Wagner, P J
a
Wells, G A
a
Wild, P S
a
Tsun Po, Y
a
Basart, H
a
Brambilla, P
a
Cambien, F
a
Dehghan, A
a
Diemert, P
a
Epstein, S E
a
Evans, A
a
Ferrario, M
a
Gauguier, D
a
Hazen, S L
a
Holm, H
a
Iribarren, C
a
Jang, Y
a
Kahonen M
a
Kee, F
a
Kim, H S
a
Klopp, N
a
Kuulasmaa, K
a
Laaksonen, R
a
Ouwehand, W H
a
Parish, S
a
Park, J E
a
Rader, D J
a
Shah, S
a
Stark, K
a
Wallentin, L
a
Zimmermann, M E
a
Nieminen, M S
a
Sandhu, M S
a
Pastinen, T
a
Zalloua, P A
a
Siegbahn, A
a
Schreiber, S
a
Ripatti, S
a
Blankenberg, S S
a
O'donnell, C J
a
Reilly, M P
a
Collins, R
a
Roberts, R
a
Pattaro, C
a
Kottgen A
a
Garnaas, M
a
Boger C A
a
Fuchsberger, C
a
Olden, M
a
Chen, M H
a
Tin, A
a
Taliun, D
a
Li, M
a
Gao, X
a
Yang, Q
a
Hundertmark, C
a
Foster, M C
a
O'seaghdha, C M
a
Glazer, N L
a
Liu, C T
a
Struchalin, M
a
Li, G
a
Johnson, A D
a
Gierman, H J
a
Hwang, S J
a
Atkinson, E J
a
Lohman, K K
a
Cornelis, M C
a
Chouraki, V
a
Holliday, E G
a
Sorice, R
a
Deshmukh, H
a
Ulivi, S
a
Chu, A Y
a
Murgia, F
a
Imboden, M
a
Kollerits, B
a
Pistis, G
a
Launer, L J
a
Aspelund, T
a
Eiriksdottir, G
a
Mitchell, B D
a
Schmidt, H
a
Cavalieri, M
a
Rao, M
a
Hu, F B
a
de Andrade, M
a
Turner, S T
a
Ding, J
a
Andrews, J S
a
Freedman, B I
a
Doring A
a
Kolcic, I
a
Zemunik, T
a
Boban, M
a
Minelli, C
a
Wheeler, H E
a
Igl, W
a
Zaboli, G
a
Wild, S H
a
Ellinghaus, D
a
Nothlings U
a
Jacobs, G
a
Biffar, R
a
Endlich, K
a
Ernst, F
a
Kroemer, H K
a
Nauck, M
a
Stracke, S
a
Volzke H
a
Aulchenko, Y
a
Polasek, O
a
Hastie, N
a
Vitart, V
a
Helmer, C
a
Wang, J J
a
Ruggiero, D
a
Bergmann, S
a
Viikari, J
a
Nikopensius, T
a
Province, M A
a
Ketkar, S
a
Colhoun, H M
a
Doney, A
a
Robino, A
a
Giulianini, F
a
Kramer B K
a
Portas, L
a
Buckley, B M
a
Adam, M
a
Thun, G A
a
Paulweber, B
a
Haun, M
a
Sala, C
a
Metzger, M
a
Mitchell, P
a
Ciullo, M
a
Kim, S K
a
Vollenweider, P
a
Palmer, C
a
Gasparini, P
a
Pirastu, M
a
Probst Hensch, N M
a
Kronenberg, F
a
Toniolo, D
a
Coresh, J
a
Schmidt, R
a
Siscovick, D S
a
Kardia, S L
a
Curhan, G
a
Franke, A
a
Parsa, A
a
Goessling, W
a
Kao, W H
a
de Boer, I H
a
Peralta, C A
a
Akylbekova, E
a
Kramer, H
a
Arking, D E
a
Franceschini, N
a
Egan, J
a
Hernandez, D G
a
Townsend, R R
a
Lumley, T
a
Psaty, B
a
Kestenbaum, B
a
Haritunians, T
a
Mooser, V
a
Florez, J C
a
Meigs, J B
a
Lu, X
a
Leak, T S
a
Aasarod K
a
Skorpen, F
a
Baumert, J
a
Devuyst, O
a
Mychaleckyj, J C
a
Kedenko, L
a
Coassin, S
a
Hallan, S
a
Navis, G
a
Shlipak, M G
a
Bull, S B
a
Paterson, A D
a
Rotter, J I
a
Dreisbach, A W
a
Anderson, C A
a
Guo, Q
a
Henders, A
a
Lambert, A
a
Lee, S H
a
Kraft, P
a
Kennedy, S H
a
Macgregor, S
a
Missmer, S A
a
Painter, J N
a
Roseman, F
a
Treloar, S A
a
Wallace, L
a
Forsblom, C
a
Isakova, T
a
McKay, G J
a
Williams, W W
a
Sadlier, D M
a
Makinen V P
a
Swan, E J
a
Boright, A P
a
Ahlqvist, E
a
Keller, B J
a
Huang, H
a
Ahola, A
a
Fagerholm, E
a
Gordin, D
a
Harjutsalo, V
a
He, B
a
Heikkila O
a
Hietala, K
a
Kyto J
a
Lahermo, P
a
Lehto, M
a
Osterholm A M
a
Parkkonen, M
a
Pitkaniemi J
a
Rosengard Barlund M
a
Saraheimo, M
a
Sarti, C
a
Soderlund J
a
Soro Paavonen, A
a
Syreeni, A
a
Thorn, L M
a
Tikkanen, H
a
Tolonen, N
a
Tryggvason, K
a
Waden J
a
Gill, G V
a
Prior, S
a
Guiducci, C
a
Mirel, D B
a
Taylor, A
a
Hosseini, M
a
Parving, H H
a
Rossing, P
a
Tarnow, L
a
Ladenvall, C
a
Alhenc Gelas, F
a
Lefebvre, P
a
Rigalleau, V
a
Roussel, R
a
Maestroni, A
a
Maestroni, S
a
Falhammar, H
a
Gu, T
a
Mollsten A
a
Cimponeriu, D
a
Mihai, I
a
Mota, M
a
Mota, E
a
Serafinceanu, C
a
Stavarachi, M
a
Hanson, R L
a
Nelson, R G
a
Kretzler, M
a
Panduru, N M
a
Gu, H F
a
Brismar, K
a
Zerbini, G
a
Hadjadj, S
a
Marre, M
a
Lajer, M
a
Waggott, D
a
Savage, D A
a
Bain, S C
a
Martin, F
a
Godson, C
a
Groop, P H
a
Maxwell, A P
a
Sengupta, S
a
Peloso, G M
a
Ganna, A
a
Mora, S
a
Chang, H Y
a
Den Hertog, H M
a
Donnelly, L A
a
Freitag, D F
a
Gurdasani, D
a
Heikkila K
a
Johnson, T
a
Kaakinen, M
a
Kettunen, J
a
Li, X
a
Montasser, M E
a
Petersen, A K
a
Saxena, R
a
Service, S K
a
Sidore, C
a
Surakka, I
a
Teslovich, T M
a
Van den Herik, E G
a
Volcik, K A
a
Wu, Y
a
Asiki, G
a
Been, L F
a
Burnett, M S
a
Doring, A
a
Elliott, P
a
Eyjolfsson, G I
a
Goodarzi, M O
a
Gravito, M L
a
Hartikainen, A L
a
Hung, Y J
a
Jones, M R
a
Kaleebu, P
a
Khaw, K T
a
Kim, E
a
Komulainen, P
a
Lin, S Y
a
Lindstrom, J
a
Muller, G
a
Narisu, N
a
Nieminen, T V
a
Nsubuga, R N
a
Olafsson, I
a
Palotie, A
a
Papamarkou, T
a
Pomilla, C
a
Pouta, A
a
Ruokonen, A
a
Seeley, J
a
Silander, K
a
Tiret, L
a
van Pelt, L
a
Wainwright, N
a
Wijmenga, C
a
Young, E H
a
Bennett, F
a
Boomsma, D I
a
Burnier, M
a
Chen, Y D
a
Feranil, A B
a
Ferrieres, J
a
Freimer, N B
a
Hsiung, C A
a
Kesaniemi A
a
Koudstaal, P J
a
Krauss, R M
a
Kyvik, K O
a
Meneton, P
a
Moilanen, L
a
Sanghera, D K
a
Sheu, W H
a
Whitfield, J B
a
Wolffenbuttel, B H
a
Ordovas, J M
a
Rich, S S
a
Johnson, A
a
Johnson, L
a
Larson, M G
a
Levy, D
a
Newton Cheh, C
a
O'reilly, P F
a
Palmas, W
a
Rice, K M
a
Snider, H
a
Tobin, M
a
Verwoert, G
a
Verwoert, G C
a
Pihur, V
a
Heath, S
a
Sober S
a
Arora, P
a
Zhang, F
a
Lucas, G
a
Milaneschi, Y
a
Parker, A N
a
Fava, C
a
Fox, E R
a
Go, M J
a
Sjogren M
a
Vinay, D
a
Alexander, M
a
Tabara, Y
a
Shaw Hawkins, S
a
Whincup, P H
a
Shi, G
a
Seielstad, M
a
Sim, X
a
Nguyen, K D
a
Matullo, G
a
Gaunt, T R
a
Onland Moret, N C
a
Cooper, M N
a
Platou, C G
a
Org, E
a
Hardy, R
a
Dahgam, S
a
Palmen, J
a
Kuznetsova, T
a
Uiterwaal, C S
a
Adeyemo, A
a
Ludwig, B
a
Tomaszewski, M
a
Tzoulaki, I
a
Palmer, N D
a
Chang, Y P
a
Steinle, N I
a
Grobbee, D E
a
Morrison, A C
a
Najjar, S
a
Hadley, D
a
Brown, M J
a
Connell, J M
a
Day, I N
a
Lawlor, D A
a
Lawrence, R W
a
Ongen, H
a
Li, Y
a
Young, J H
a
Bis, J C
a
Bolton, J A
a
Chaturvedi, N
a
Islam, M
a
Jafar, T H
a
Kulkarni, S R
a
Howard, P
a
Guarrera, S
a
Ricceri, F
a
Emilsson, V
a
Plump, A
a
Weder, A B
a
Sun, Y V
a
Scott, L J
a
Peltonen, L
a
Vartiainen, E
a
Brand, S M
a
Staessen, J A
a
Wang, T J
a
Burton, P R
a
Artigas, M S
a
Dong, Y
a
Wang, X
a
Zhu, H
a
Rudock, M E
a
Heckbert, S R
a
Smith, N L
a
Wiggins, K L
a
Doumatey, A
a
Shriner, D
a
Veldre, G
a
Viigimaa, M
a
Kinra, S
a
Prabhakaran, D
a
Tripathy, V
a
Langefeld, C D
a
Rosengren, A
a
Thelle, D S
a
Corsi, A M
a
Singleton, A
a
Hilton, G
a
Salako, T
a
Iwai, N
a
Kita, Y
a
Ogihara, T
a
Ohkubo, T
a
Okamura, T
a
Ueshima, H
a
Umemura, S
a
Eyheramendy, S
a
Meitinger, T
a
Cho, Y S
a
Kim, H L
a
Scott, J
a
Sehmi, J S
a
Hedblad, B
a
Nilsson, P
a
Smith, G D
a
Raffel, L J
a
Yao, J
a
Schwartz, S M
a
Ikram, M
a
W, Longstreth
a
Mosley, T H
a
Seshadri, S
a
Shrine, N R
a
Wain, L V
a
Zitting, P
a
Cooper, J A
a
van Gilst, W H
a
Janipalli, C S
a
Mani, K
a
Yajnik, C S
a
Mattace Raso, F U
a
Lakatta, E G
a
Orru, M
a
Scuteri, A
a
Ala Korpela, M
a
Kangas, A J
a
Soininen, P
a
Tukiainen, T
a
Wurtz P
a
Ong, R T
a
Dorr M
a
Galan, P
a
Hercberg, S
a
Lathrop, M
a
Zelenika, D
a
Zhai, G
a
Meschia, J F
a
Sharma, P
a
Terzic, J
a
Kumar, M
a
Denniff, M
a
Zukowska Szczechowska, E
a
Wagenknecht, L E
a
Fowkes, F
a
Charchar, F J
a
Guo, X
a
Rotimi, C
a
Bots, M L
a
Brand, E
a
Talmud, P J
a
Nyberg, F
a
Laan, M
a
Palmer, L J
a
van der Schouw, Y T
a
Casas, J P
a
Vineis, P
a
Ganesh, S K
a
Wong, T Y
a
Tai, E S
a
Morris, R W
a
Marmot, M G
a
Miki, T
a
Chandak, G R
a
Zhu, X
a
Elosua, R
a
Soranzo, N
a
Sijbrands, E J
a
Uda, M
a
Vasan, R S
a
Alizadeh, B Z
a
de Boer, R A
a
Boezen, H M
a
Hillege, H L
a
van der Klauw, M M
a
Ormel, J
a
Rosmalen, J G
a
Slaets, J P
a
Lagou, V
a
Welch, R P
a
Wheeler, E
a
Rehnberg, E
a
Rasmussen Torvik, L J
a
Lecoeur, C
a
Johnson, P C
a
Sennblad, B
a
Salo, P
a
Timpson, N J
a
Evans, D M
a
St Pourcain, B
a
Bielak, L F
a
Horikoshi, M
a
Navarro, P
a
Raychaudhuri, S
a
Chen, H
a
Rybin, D
a
Willems, S M
a
Song, K
a
An, P
a
Marullo, L
a
Jansen, H
a
Pankow, J
a
Edkins, S
a
Varga, T V
a
Oksa, H
a
Antonella, M
a
Kong, A
a
Herder, C
a
Antti, J
a
Small, K
a
Miljkovic, I
a
Atalay, M
a
Kiess, W
a
Smit, J H
a
Campbell, S
a
Fowkes, G R
a
Rathmann, W
a
Maerz, W
a
Watanabe, R M
a
de Geus, E J
a
Penninx, B W
a
Toenjes, A
a
Peyser, P A
a
Korner A
a
Dupuis, J
a
Cucca, F
a
Balkau, B
a
Bouatia Naji, N
a
Purcell, S
a
Musunuru, K
a
Ardissino, D
a
Mannucci, P M
a
Anand, S
a
Engert, J C
a
Morgan, T
a
Spertus, J A
a
Stoll, M
a
Girelli, D
a
McKeown, P P
a
Patterson, C C
a
Merlini, P A
a
Berzuini, C
a
Bernardinelli, L
a
Peyvandi, F
a
Tubaro, M
a
Celli, P
a
Fetiveau, R
a
Marziliano, N
a
Casari, G
a
Galli, M
a
Ribichini, F
a
Rossi, M
a
Bernardi, F
a
Zonzin, P
a
Piazza, A
a
Yee, J
a
Friedlander, Y
a
Marrugat, J
a
Subirana, I
a
Sala, J
a
Ramos, R
a
Williams, G
a
Nathan, D M
a
Macrae, C A
a
Berglund, G
a
Asselta, R
a
Duga, S
a
Spreafico, M
a
Daly, M J
a
Nemesh, J
a
Korn, J M
a
Surti, A
a
Gianniny, L
a
Parkin, M
a
Burtt, N
a
Gabriel, S B
a
Wright, B J
a
Ball, S G
a
Schunkert, I
a
Linsel Nitschke, P
a
Lieb, W
a
Fischer, M
a
Grosshennig, A
a
Preuss, M
a
Scholz, M
a
Chen, Z
a
Wilensky, R
a
Matthai, W
a
Qasim, A
a
Hakonarson, H H
a
Devaney, J
a
Pichard, A D
a
Kent, K M
a
Satler, L
a
Lindsay, J M
a
Waksman, R
a
Knouff, C W
a
Scheffold, T
a
Berger, K
a
Huge, A
a
Martinelli, N
a
Olivieri, O
a
Corrocher, R
a
Holm H
a
Xie, C
a
Ahmadi, K R
a
Ainali, C
a
Bataille, V
a
Bell, J T
a
Buil, A
a
Dermitzakis, E T
a
Dimas, A S
a
Durbin, R
a
Glass, D
a
Hassanali, N
a
Ingle, C
a
Knowles, D
a
Krestyaninova, M
a
Lowe, C E
a
Meduri, E
a
Di Meglio, P
a
Montgomery, S B
a
Nestle, F O
a
Nica, A C
a
Nisbet, J
a
O'rahilly, S
a
Parts, L
a
Potter, S
a
Sekowska, M
a
Shin, S Y
a
Surdulescu, G
a
Travers, M E
a
Tsaprouni, L
a
Tsoka, S
a
Wilk, A
a
Yang, T P
a
Higashio, J
a
Williams, R
a
Nato, A
a
Ambite, J L
a
Deelman, E
a
Manolio, T
a
Heiss, G
a
Taylor, K
a
Avery, C
a
Graff, M
a
Lin, D
a
Quibrera, M
a
Cochran, B
a
Kao, L
a
Umans, J
a
Cole, S
a
Maccluer, J
a
Person, S
a
Gross, M
a
Fornage, M
a
Durda, P
a
Jenny, N
a
Patsy, B
a
Arnold, A
a
Buzkova, P
a
Haines, J
a
Murdock, D
a
Glenn, K
a
Brown Gentry, K
a
Thornton Wells, T
a
Dumitrescu, L
a
Bush, W S
a
Mitchell, S L
a
Goodloe, R
a
Wilson, S
a
Boston, J
a
Malinowski, J
a
Restrepo, N
a
Oetjens, M
a
Fowke, J
a
Spencer, K
a
Pendergrass, S
a
Park, L
a
Tiirikainen, M
a
Kolonel, L
a
Cheng, I
a
Wang, H
a
Shohet, R
a
Stram, D
a
Henderson, B
a
Monroe, K
a
Anderson, G
a
Carlson, C
a
Prentice, R
a
Lacroix, A
a
Wu, C
a
Carty, C
a
Rosse, S
a
Young, A
a
Kocarnik, J
a
Lin, Y
a
Jackson, R
a
Duggan, D
a
Kuller, L
a
He, C
a
Sulem, P
a
Barbalic, M
a
Broer, L
a
Byrne, E M
a
Gudbjartsson, D F
a
McArdle, P F
a
Porcu, E
a
van Wingerden, S W
a
Zhuang, W V
a
Lauc, L B
a
Broekmans, F J
a
Burri, A
a
Chen, C
a
Corre, T
a
Coviello, A D
a
D'adamo, P
a
Davies, G
a
Deary, I J
a
Ebrahim, S
a
Fauser, B C
a
Ferreli, L
a
Folsom, A R
a
Hankinson, S E
a
Hass, M
a
Janssens, A C
a
Karasik, D
a
Keyzer, J
a
Kiel, D P
a
Lahti, J
a
Lai, S
a
Laisk, T
a
Laven, J S
a
Liu, J
a
Lopez, L M
a
Louwers, Y V
a
Marongiu, M
a
Klaric, I M
a
Masciullo, C
a
Melzer, D
a
Newman, A B
a
Pare G
a
Peeters, P H
a
Pop, V J
a
Raikkonen K
a
Salumets, A
a
Stacey, S N
a
Starr, J M
a
Stathopoulou, M G
a
Styrkarsdottir, U
a
Tenesa, A
a
Tryggvadottir, L
a
Tsui, K
a
van Dam, R M
a
van Gils, C H
a
van Nierop, P
a
Vink, J M
a
Voorhuis, M
a
Widen, E
a
Wijnands Van Gent, C J
a
Yerges Armstrong, L M
a
Zgaga, L
a
Zygmunt, M
a
Buring, J E
a
Crisponi, L
a
Demerath, E W
a
Streeten, E A
a
Murray, A
a
Visser, J A
a
Lunetta, K L
a
Elks, C E
a
Cousminer, D L
a
Koller, D L
a
Lin, P
a
Smith, E N
a
Warrington, N M
a
Alavere, H
a
Berenson, G S
a
Blackburn, H
a
Busonero, F
a
Chen, W
a
Couper, D
a
Easton, D F
a
Eriksson, J
a
Foroud, T
a
Kilpelainen T O
a
Li, S
a
Murray, S S
a
Ness, A R
a
Northstone, K
a
Peacock, M
a
Pennell, C E
a
Pharoah, P
a
Rafnar, T
a
Rice, J P
a
Ring, S M
a
Schork, N J
a
Segre A V
a
Sovio, U
a
Srinivasan, S R
a
Tammesoo, M L
a
van Meurs, J B
a
Young, L
a
Bierut, L J
a
Econs, M J
a
more..
a
NONE
Author keywords
[No Author keywords available]
Indexed keywords
BODY MASS;
GENETIC ANALYSIS;
OBESITY;
ARTICLE;
BODY MASS;
COPY NUMBER VARIATION;
DISEASE COURSE;
ENERGY METABOLISM;
GENE EXPRESSION;
GENE FREQUENCY;
GENE LINKAGE DISEQUILIBRIUM;
GENETIC ASSOCIATION;
GENETIC VARIABILITY;
HEREDITY;
HUMAN;
INSULIN RELEASE;
NONHUMAN;
OBESITY;
PHENOTYPE;
PRIORITY JOURNAL;
QUANTITATIVE TRAIT LOCUS;
RECEIVER OPERATING CHARACTERISTIC;
ADIPOGENESIS;
AGE;
ANCESTRY GROUP;
ETHNOLOGY;
EUROPE;
FEMALE;
GENETIC PREDISPOSITION;
GENETICS;
GENOME-WIDE ASSOCIATION STUDY;
MALE;
META ANALYSIS;
METABOLISM;
SECRETION (PROCESS);
SINGLE NUCLEOTIDE POLYMORPHISM;
SYNAPSE;
GLUTAMIC ACID;
INSULIN;
ADIPOGENESIS;
ADIPOSITY;
AGE FACTORS;
BODY MASS INDEX;
CONTINENTAL POPULATION GROUPS;
ENERGY METABOLISM;
EUROPE;
FEMALE;
GENETIC PREDISPOSITION TO DISEASE;
GENOME-WIDE ASSOCIATION STUDY;
GLUTAMIC ACID;
HUMANS;
INSULIN;
MALE;
OBESITY;
POLYMORPHISM, SINGLE NUCLEOTIDE;
QUANTITATIVE TRAIT LOCI;
SYNAPSES;
EID : 84923171580
PISSN : 00280836
EISSN : 14764687
Source Type : Journal
DOI : 10.1038/nature14177
Document Type : Article
1
0030843960
Genetic and environmental factors in relative body weight and human adiposity
Maes, H. H., Neale, M. C.& Eaves, L. J. Genetic and environmental factors in relative body weight and human adiposity. Behav. Genet. 27, 325-351 (1997).
(1997)
Behav. Genet.
, vol.27
, pp. 325-351
Maes, H.H.1
Neale, M.C.2
Eaves, L.J.3
2
84862909349
Five years of GWAS discovery
Visscher, P. M., Brown, M. A., McCarthy, M. I. & Yang, J. Five years of GWAS discovery. Am. J. Hum. Genet. 90, 7-24 (2012).
(2012)
Am. J. Hum. Genet.
, vol.90
, pp. 7-24
Visscher, P.M.1
Brown, M.A.2
McCarthy, M.I.3
Yang, J.4
3
84878502589
Using extended genealogy to estimate components of heritability for 23 quantitative and dichotomous traits
Zaitlen, N. et al. Using extended genealogy to estimate components of heritability for 23 quantitative and dichotomous traits. PLoS Genet. 9, e1003520 (2013).
(2013)
PLoS Genet.
, vol.9
Zaitlen, N.1
4
84888376082
Genome-wide association studies of obesity and metabolic syndrome
Fall, T. & Ingelsson, E. Genome-wide association studies of obesity and metabolic syndrome. Mol. Cell. Endocrinol. 382, 740-757 (2014).
(2014)
Mol. Cell. Endocrinol.
, vol.382
, pp. 740-757
Fall, T.1
Ingelsson, E.2
5
78049337953
Association analyses of 249,796 individuals reveal 18 newloci associated with body mass index
Speliotes, E. K. et al. Association analyses of 249,796 individuals reveal 18 newloci associated with body mass index. Nature Genet. 42, 937-948 (2010).
(2010)
Nature Genet.
, vol.42
, pp. 937-948
Speliotes, E.K.1
6
58149163142
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
Willer, C. J. et al. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nature Genet. 41, 25-34 (2009).
(2009)
Nature Genet.
, vol.41
, pp. 25-34
Willer, C.J.1
7
84865693681
Themetabochip, a customgenotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits
Voight, B. F. et al. Themetabochip, a customgenotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits. PLoS Genet. 8, e1002793 (2012).
(2012)
PLoS Genet.
, vol.8
Voight, B.F.1
8
79960895140
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile
Kilpelainen, T. O. et al. Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nature Genet. 43, 753-760 (2011).
(2011)
Nature Genet.
, vol.43
, pp. 753-760
Kilpelainen, T.O.1
9
84860350999
A genome-wide association meta-analysis identifies new childhood obesity loci
Bradfield, J. P. et al. A genome-wide association meta-analysis identifies new childhood obesity loci. Nature Genet. 44, 526-531 (2012).
(2012)
Nature Genet.
, vol.44
, pp. 526-531
Bradfield, J.P.1
10
84878720938
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry
Monda, K. L. et al. A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nature Genet. 45, 690-696 (2013).
(2013)
Nature Genet.
, vol.45
, pp. 690-696
Monda, K.L.1
11
84878594902
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
Berndt, S. I. et al. Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nature Genet. 45, 501-512 (2013).
(2013)
Nature Genet.
, vol.45
, pp. 501-512
Berndt, S.I.1
12
84871223778
Gene-centric meta-analyses of 108 912 individuals confirm known bodymass index lociand reveal three novel signals.Hum.Mol
Guo, Y. et al. Gene-centric meta-analyses of 108 912 individuals confirm known bodymass index lociand reveal three novel signals.Hum.Mol. Genet. 22, 184-201 (2013).
(2013)
Genet.
, vol.22
, pp. 184-201
Guo, Y.1
13
84908890496
Defining the role of common variation in the genomic and biological architecture of adult human height
Wood, A. R. et al. Defining the role of common variation in the genomic and biological architecture of adult human height. Nature Genet. 46, 1173-1186 (2014).
(2014)
Nature Genet.
, vol.46
, pp. 1173-1186
Wood, A.R.1
14
84870502629
Bayesian refinement of association signals for 14 loci in 3 common diseases
Maller, J. B. et al. Bayesian refinement of association signals for 14 loci in 3 common diseases. Nature Genet. 44, 1294-1301 (2012).
(2012)
Nature Genet.
, vol.44
, pp. 1294-1301
Maller, J.B.1
15
34547782270
A Bayesian measure of the probability of false discovery in genetic epidemiology studies
Wakefield, J. A Bayesian measure of the probability of false discovery in genetic epidemiology studies. Am. J. Hum. Genet. 81, 208-227 (2007).
(2007)
Am. J. Hum. Genet.
, vol.81
, pp. 208-227
Wakefield, J.1
16
84873504695
Asystematic mapping approach of 16q12.2/FTO and BMI in more than 20,000 African Americans narrows in on the underlying functional variation: Results from the Population Architecture using Genomics and Epidemiology (PAGE) study
Peters, U. et al. A systematic mapping approach of 16q12.2/FTO and BMI in more than 20,000 African Americans narrows in on the underlying functional variation: results from the Population Architecture using Genomics and Epidemiology (PAGE) study. PLoS Genet. 9, e1003171 (2013).
(2013)
PLoS Genet.
, vol.9
Peters, U.1
17
0000366020
An overview of the Health and Retirement Study
Juster, F. T. & Suzman, R. An overview of the Health and Retirement Study. J. Hum. Resour. 30, S7-S56 (1995).
(1995)
J. Hum. Resour.
, vol.30
, pp. S7-S56
Juster, F.T.1
Suzman, R.2
18
84896318010
Weight loss, exercise or both and cardiometabolic risk factors in obese older adults: Results of a randomized controlled trial
Bouchonville, M. et al. Weight loss, exercise or both and cardiometabolic risk factors in obese older adults: results of a randomized controlled trial. Int. J. Obes. 38, 423-431 (2013).
(2013)
Int. J. Obes.
, vol.38
, pp. 423-431
Bouchonville, M.1
19
78650856517
GCTA: A tool for genome-wide complex trait analysis
Yang, J., Lee, S. H., Goddard, M. E. & Visscher, P. M. GCTA: a tool for genome-wide complex trait analysis. Am. J. Hum. Genet. 88, 76-82 (2011).
(2011)
Am. J. Hum. Genet.
, vol.88
, pp. 76-82
Yang, J.1
Lee, S.H.2
Goddard, M.E.3
Visscher, P.M.4
20
84862832570
Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits
Yang, J. et al. Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits. Nature Genet. 44, 369-375 (2012).
(2012)
Nature Genet.
, vol.44
, pp. 369-375
Yang, J.1
21
84923096381
Biological interpretation of genome-wide association studies using predicted gene functions
Pers, T. et al. Biological interpretation of genome-wide association studies using predicted gene functions. Nat. Commun. 5, 5890 (2014).
(2014)
Nat. Commun.
, vol.5
, pp. 5890
Pers, T.1
22
84865790047
An integrated encyclopedia of DNA elements in the human genome
The ENCODE Project Consortium. An integrated encyclopedia of DNA elements in the human genome. Nature 489, 57-74 (2012).
(2012)
Nature
, vol.489
, pp. 57-74
The ENCODE Project Consortium1
23
77957940722
The NIH roadmap epigenomics mapping consortium
Bernstein, B. E. et al. The NIH Roadmap Epigenomics Mapping Consortium. Nature Biotechnol. 28, 1045-1048 (2010).
(2010)
Nature Biotechnol.
, vol.28
, pp. 1045-1048
Bernstein, B.E.1
24
77957342306
Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits
Segrè, A. V., Groop, L., Mootha, V. K., Daly, M. J. & Altshuler, D. Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits. PLoS Genet. 6, e1001058 (2010).
(2010)
PLoS Genet.
, vol.6
Segrè, A.V.1
Groop, L.2
Mootha, V.K.3
Daly, M.J.4
Altshuler, D.5
25
32044465506
TOR signaling in growth andmetabolism
Wullschleger, S., Loewith, R.& Hall, M. N. TOR signaling in growth andmetabolism. Cell 124, 471-484 (2006).
(2006)
Cell
, vol.124
, pp. 471-484
Wullschleger, S.1
Loewith, R.2
Hall, M.N.3
26
77957947562
Hundreds of variants clustered in genomic loci and biological pathways affect human height
Lango Allen, H. et al. Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature 467, 832-838 (2010).
(2010)
Nature
, vol.467
, pp. 832-838
Lango Allen, H.1
27
67651205715
Identifying relationships among genomic disease regions: Predicting genes at pathogenic SNP associations and rare deletions
Raychaudhuri, S. et al. Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions. PLoS Genet. 5, e1000534 (2009).
(2009)
PLoS Genet.
, vol.5
Raychaudhuri, S.1
28
84881356818
Contributionof32GWAS-identifiedcommonvariants tosevereobesity in European adults referred for bariatric surgery
Magi,R. et al.Contributionof32GWAS-identifiedcommonvariants tosevereobesity in European adults referred for bariatric surgery. PLoS ONE 8, e70735 (2013).
(2013)
PLoS ONE
, vol.8
Magi, R.1
29
84864488946
Functional inactivation of the genome-wide association study obesity gene neuronal growth regulator 1 in mice causes a body mass phenotype
Lee, A. W. et al. Functional inactivation of the genome-wide association study obesity gene neuronal growth regulator 1 in mice causes a body mass phenotype. PLoS ONE 7, e41537 (2012).
(2012)
PLoS ONE
, vol.7
Lee, A.W.1
30
80052922112
Hunger states switch a flip-flop memory circuit via a synaptic AMPK-dependent positive feedback loop
Yang, Y., Atasoy, D., Su, H. H. & Sternson, S. M. Hunger states switch a flip-flop memory circuit via a synaptic AMPK-dependent positive feedback loop. Cell 146, 992-1003 (2011).
(2011)
Cell
, vol.146
, pp. 992-1003
Yang, Y.1
Atasoy, D.2
Su, H.H.3
Sternson, S.M.4
31
84859215897
Deciphering a neuronal circuit that mediates appetite
Wu, Q., Clark, M. S. & Palmiter, R. D. Deciphering a neuronal circuit that mediates appetite. Nature 483, 594-597 (2012).
(2012)
Nature
, vol.483
, pp. 594-597
Wu, Q.1
Clark, M.S.2
Palmiter, R.D.3
32
84872056027
Melanocortin-4 receptor regulates hippocampal synaptic plasticity through a protein kinase A-dependent mechanism
Shen, Y., Fu, W. Y.,Cheng, E. Y., Fu, A. K.&Ip, N. Y.Melanocortin-4 receptor regulates hippocampal synaptic plasticity through a protein kinase A-dependent mechanism. J. Neurosci. 33, 464-472 (2013).
(2013)
J. Neurosci.
, vol.33
, pp. 464-472
Shen, Y.1
Fu, W.Y.2
Cheng, E.Y.3
Fu, A.K.4
Ip, N.Y.5
33
0034076786
Cellular actions of topiramate: Blockade of kainate-evoked inward currents in cultured hippocampal neurons
Gibbs, J. W., III, Sombati, S., DeLorenzo, R. J. & Coulter, D. A. Cellular actions of topiramate: blockade of kainate-evoked inward currents in cultured hippocampal neurons. Epilepsia 41 (suppl. 1), S10-S16 (2000).
(2000)
Epilepsia
, vol.41
, pp. S10-S16
Gibbs, J.W.1
Sombati, S.2
Delorenzo, R.J.3
Coulter, D.A.4
34
0442328037
Modulation by topiramate of AMPA and kainate mediated calcium influx in cultured cerebral cortical, hippocampal and cerebellar neurons
Poulsen, C. F. et al. Modulation by topiramate of AMPA and kainate mediated calcium influx in cultured cerebral cortical, hippocampal and cerebellar neurons. Neurochem. Res. 29, 275-282 (2004).
(2004)
Neurochem. Res.
, vol.29
, pp. 275-282
Poulsen, C.F.1
35
84856957894
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
Henao-Mejia, J. et al. Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. Nature 482, 179-185 (2012).
(2012)
Nature
, vol.482
, pp. 179-185
Henao-Mejia, J.1
36
77956586071
LocusZoom: Regional visualization of genome-wide association scan results
Pruim, R. J. et al. LocusZoom: regional visualization of genome-wide association scan results. Bioinformatics 26, 2336-2337 (2010).
(2010)
Bioinformatics
, vol.26
, pp. 2336-2337
Pruim, R.J.1
37
35348983887
A second generation human haplotype map of over 3.1 million SNPs
Frazer, K. A. et al. A second generation human haplotype map of over 3.1 million SNPs. Nature 449, 851-861 (2007).
(2007)
Nature
, vol.449
, pp. 851-861
Frazer, K.A.1
38
84899540947
Quality control and conduct of genome-wide association metaanalyses
Winkler, T. W. et al. Quality control and conduct of genome-wide association metaanalyses. Nature Protocols 9, 1192-1212 (2014).
(2014)
Nature Protocols
, vol.9
, pp. 1192-1212
Winkler, T.W.1
39
77955894071
METAL: Fast and efficient meta-analysis of genomewide association scans
Willer, C. J., Li, Y. & Abecasis, G. R. METAL: fast and efficient meta-analysis of genomewide association scans. Bioinformatics 26, 2190-2191 (2010).
(2010)
Bioinformatics
, vol.26
, pp. 2190-2191
Willer, C.J.1
Li, Y.2
Abecasis, G.R.3
40
0032714352
Genomic control for association studies
Devlin, B. & Roeder, K. Genomic control for association studies. Biometrics 55, 997-1004 (1999).
(1999)
Biometrics
, vol.55
, pp. 997-1004
Devlin, B.1
Roeder, K.2
41
84862777036
Meta-analysis identifies commonvariants associated withbodymass index in east Asians
Wen, W.et al.Meta-analysis identifies commonvariants associated withbodymass index in east Asians. Nature Genet. 44, 307-311 (2012).
(2012)
Nature Genet.
, vol.44
, pp. 307-311
Wen, W.1
42
84879677633
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits
Randall, J. C. et al. Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet. 9, e1003500 (2013).
(2013)
PLoS Genet.
, vol.9
Randall, J.C.1
43
77956534324
ANNOVAR: Functional annotation of genetic variants from high-throughput sequencing data
Wang, K., Li, M. & Hakonarson, H. ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data. Nucleic Acids Res. 38, e164 (2010).
(2010)
Nucleic Acids Res.
, vol.38
, pp. e164
Wang, K.1
Li, M.2
Hakonarson, H.3
44
77951640946
A method and server for predicting damaging missense mutations
Adzhubei, I. A. et al. A method and server for predicting damaging missense mutations. Nature Methods 7, 248-249 (2010).
(2010)
Nature Methods
, vol.7
, pp. 248-249
Adzhubei, I.A.1
45
85152093074
NHLBI Exome Sequencing Project (ESP), Exome Variant Server; http://evs.gs.washington.edu/EVS/.
NHLBI Exome Sequencing Project (ESP), Exome Variant Server; http://evs.gs.washington.edu/EVS/.
46
0035026704
Predicting deleterious amino acid substitutions
Ng, P. C. & Henikoff, S. Predicting deleterious amino acid substitutions. Genome Res. 11, 863-874 (2001).
(2001)
Genome Res.
, vol.11
, pp. 863-874
Ng, P.C.1
Henikoff, S.2
47
84975804424
Mapping copy number variation by population-scale genome sequencing
Mills, R. E. et al. Mapping copy number variation by population-scale genome sequencing. Nature 470, 59-65 (2011).
(2011)
Nature
, vol.470
, pp. 59-65
Mills, R.E.1
48
41349095280
Genetics of gene expression and its effect on disease
Emilsson, V. et al.Genetics of gene expression and its effect on disease.Nature452, 423-428 (2008).
(2008)
Nature
, vol.452
, pp. 423-428
Emilsson, V.1
49
77950339092
Integrating pathway analysis and genetics of gene expression for genome-wide association studies
Zhong, H., Yang, X., Kaplan, L. M., Molony, C. & Schadt, E. E. Integrating pathway analysis and genetics of gene expression for genome-wide association studies. Am. J. Hum. Genet. 86, 581-591 (2010).
(2010)
Am. J. Hum. Genet.
, vol.86
, pp. 581-591
Zhong, H.1
Yang, X.2
Kaplan, L.M.3
Molony, C.4
Schadt, E.E.5
50
84866871814
Mapping cis-and trans-regulatory effects across multiple tissues in twins
Grundberg, E. et al. Mapping cis-and trans-regulatory effects across multiple tissues in twins. Nature Genet. 44, 1084-1089 (2012).
(2012)
Nature Genet.
, vol.44
, pp. 1084-1089
Grundberg, E.1
51
34548805282
Agenome-wide association study of global gene expression
Dixon, A. L. et al. A genome-wide association study of global gene expression. Nature Genet. 39, 1202-1207 (2007).
(2007)
Nature Genet.
, vol.39
, pp. 1202-1207
Dixon, A.L.1
52
80052322958
Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA
Fehrmann, R. S. et al. Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA. PLoS Genet. 7, e1002197 (2011).
(2011)
PLoS Genet.
, vol.7
Fehrmann, R.S.1
53
65549126774
Genetic structure of Europeans: A view from the North-East
Nelis, M. et al. Genetic structure of Europeans: a view from the North-East. PLoS ONE 4, e5472 (2009).
(2009)
PLoS ONE
, vol.4
, pp. e5472
Nelis, M.1
54
36549053104
A survey of genetic human cortical gene expression
Myers, A. J. et al. A survey of genetic human cortical gene expression. Nature Genet. 39, 1494-1499 (2007).
(2007)
Nature Genet.
, vol.39
, pp. 1494-1499
Myers, A.J.1
55
84885018609
Systematic identification of trans eQTLs as putative drivers of known disease associations
Westra, H. J. et al. Systematic identification of trans eQTLs as putative drivers of known disease associations. Nature Genet. 45, 1238-1243 (2013).
(2013)
Nature Genet.
, vol.45
, pp. 1238-1243
Westra, H.J.1
56
84868337361
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
Morris, A. P. et al.Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nature Genet. 44, 981-990 (2012).
(2012)
Nature Genet.
, vol.44
, pp. 981-990
Morris, A.P.1
57
84871969762
Large-scale association analysis identifies new risk loci for coronary artery disease
Deloukas, P. et al. Large-scale association analysis identifies new risk loci for coronary artery disease. Nature Genet. 45, 25-33 (2013).
(2013)
Nature Genet.
, vol.45
, pp. 25-33
Deloukas, P.1
58
80053907554
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
Ehret, G. B. et al. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature 478, 103-109 (2011).
(2011)
Nature
, vol.478
, pp. 103-109
Ehret, G.B.1
59
85152030351
Shungin, D. et al. New genetic loci link adipose and insulin biology to body fat distribution. Nature http://dx.doi.org/nature14132 (this issue).
Shungin, D. et al. New genetic loci link adipose and insulin biology to body fat distribution. Nature http://dx.doi.org/nature14132 (this issue).
60
84887099827
Discovery and refinement of loci associated with lipid levels
Willer, C. et al. Discovery and refinement of loci associated with lipid levels. Nature Genet. 45, 1274-1283 (2013).
(2013)
Nature Genet.
, vol.45
, pp. 1274-1283
Willer, C.1
61
84865693929
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
Scott, R. A. et al. Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nature Genet. 44, 991-1005 (2012).
(2012)
Nature Genet.
, vol.44
, pp. 991-1005
Scott, R.A.1
62
84861614905
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
Manning, A. K. et al. A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nature Genet. 44, 659-669 (2012).
(2012)
Nature Genet.
, vol.44
, pp. 659-669
Manning, A.K.1
63
75749091912
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
Saxena, R. et al. Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nature Genet. 42, 142-148 (2010).
(2010)
Nature Genet.
, vol.42
, pp. 142-148
Saxena, R.1
64
84859238629
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: A multi-ethnic meta-analysis of 45,891 individuals
Dastani, Z. et al. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet. 8, e1002607 (2012).
(2012)
PLoS Genet.
, vol.8
Dastani, Z.1
65
84859224378
Genome-wide association and functional follow-up reveals new loci for kidney function
Pattaro, C. et al. Genome-wide association and functional follow-up reveals new loci for kidney function. PLoS Genet. 8, e1002584 (2012).
(2012)
PLoS Genet.
, vol.8
Pattaro, C.1
66
79952350496
CUBN is a gene locus for albuminuria
Boger, C. A. et al. CUBN is a gene locus for albuminuria. J. Am. Soc. Nephrol. 22, 555-570 (2011).
(2011)
J. Am. Soc. Nephrol.
, vol.22
, pp. 555-570
Boger, C.A.1
67
84862777492
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways
Stolk, L. et al. Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nature Genet. 44, 260-268 (2012).
(2012)
Nature Genet.
, vol.44
, pp. 260-268
Stolk, L.1
68
84947899470
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies
Elks, C. E. et al. Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nature Genet. 42, 1077-1085 (2010).
(2010)
Nature Genet.
, vol.42
, pp. 1077-1085
Elks, C.E.1
69
84864378869
Association testing of previously reported variants in a large case-control meta-analysis of diabetic nephropathy
Williams, W. W. et al. Association testing of previously reported variants in a large case-control meta-analysis of diabetic nephropathy. Diabetes 61, 2187-2194 (2012).
(2012)
Diabetes
, vol.61
, pp. 2187-2194
Williams, W.W.1
70
84866889255
New susceptibility loci associated with kidney disease in type 1 diabetes
Sandholm, N. et al. New susceptibility loci associated with kidney disease in type 1 diabetes. PLoS Genet. 8, e1002921 (2012).
(2012)
PLoS Genet.
, vol.8
Sandholm, N.1
71
67249117049
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
Hindorff, L. A. et al. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc. Natl Acad. Sci. USA 106, 9362-9367 (2009).
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 9362-9367
Hindorff, L.A.1
72
79955564639
Measuring reproducibility of highthroughput experiments
Li, Q., Brown, J. B., Huang, H. & Bickel, P. J. Measuring reproducibility of highthroughput experiments. Ann. Appl. Stat. 5, 1752-1779 (2011).
(2011)
Ann. Appl. Stat.
, vol.5
, pp. 1752-1779
Li, Q.1
Brown, J.B.2
Huang, H.3
Bickel, P.J.4
73
84866127830
Identifying ChIP-seq enrichment using MACS
Feng, J., Liu, T., Qin, B., Zhang, Y. & Liu, X. S. Identifying ChIP-seq enrichment using MACS. Nature Protocols 7, 1728-1740 (2012).
(2012)
Nature Protocols
, vol.7
, pp. 1728-1740
Feng, J.1
Liu, T.2
Qin, B.3
Zhang, Y.4
Liu, X.S.5
74
84975795680
An integrated map of genetic variation from 1,092 human genomes
Abecasis, G. R. et al. An integrated map of genetic variation from 1,092 human genomes. Nature 491, 56-65 (2012).
(2012)
Nature
, vol.491
, pp. 56-65
Abecasis, G.R.1
75
84964308876
Gene expression analysis identifies global gene dosage sensitivity in cancer
Fehrmann, R. S. et al. Gene expression analysis identifies global gene dosage sensitivity in cancer. Nature Genet. 47, 115-125 (2015).
(2015)
Nature Genet.
, vol.47
, pp. 115-125
Fehrmann, R.S.1