-
1
-
-
33646799069
-
Global and regional burden of disease and risk factors, 2001: Systematic analysis of population health data
-
Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJ. Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet 2006;367:1747-57.
-
(2006)
Lancet
, vol.367
, pp. 1747-1757
-
-
Lopez, A.D.1
Mathers, C.D.2
Ezzati, M.3
Jamison, D.T.4
Murray, C.J.5
-
2
-
-
4444382796
-
Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): Case-control study
-
Yusuf S, Hawken S, Ounpuu S, et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet 2004;364:937-52.
-
(2004)
Lancet
, vol.364
, pp. 937-952
-
-
Yusuf, S.1
Hawken, S.2
Ounpuu, S.3
-
3
-
-
0028330005
-
Genetic susceptibility to death from coronary heart disease in a study of twins
-
Marenberg ME, Risch N, Berkman LF, Floderus B, de Faire U. Genetic susceptibility to death from coronary heart disease in a study of twins. N Engl J Med 1994;330:1041-6.
-
(1994)
N Engl J Med
, vol.330
, pp. 1041-1046
-
-
Marenberg, M.E.1
Risch, N.2
Berkman, L.F.3
Floderus, B.4
de Faire, U.5
-
4
-
-
33947285368
-
What genome-wide association studies can do for medicine
-
Christensen K, Murray JC. What genome-wide association studies can do for medicine. N Engl J Med 2007;356:1094-7.
-
(2007)
N Engl J Med
, vol.356
, pp. 1094-1097
-
-
Christensen, K.1
Murray, J.C.2
-
5
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
Wellcome Trust Case Control Consortium
-
Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007;447:661-78.
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
6
-
-
28144451633
-
A genomewide linkage study of 1,933 families affected by premature coronary artery disease: The British Heart Foundation (BHF) Family Heart Study
-
Samani NJ, Burton P, Mangino M, et al. A genomewide linkage study of 1,933 families affected by premature coronary artery disease: The British Heart Foundation (BHF) Family Heart Study. Am J Hum Genet 2005;77:1011-20.
-
(2005)
Am J Hum Genet
, vol.77
, pp. 1011-1020
-
-
Samani, N.J.1
Burton, P.2
Mangino, M.3
-
7
-
-
85030512340
-
Effect of a common X-linked angiotensin II type 2-receptor gene polymorphism (-1332 G/A) on the occurrence of premature myocardial infarction and stenotic atherosclerosis requiring revascularization
-
in press
-
Alfakih K, Brown B, Lawrance RA, et al. Effect of a common X-linked angiotensin II type 2-receptor gene polymorphism (-1332 G/A) on the occurrence of premature myocardial infarction and stenotic atherosclerosis requiring revascularization. Atherosclerosis (in press).
-
Atherosclerosis
-
-
Alfakih, K.1
Brown, B.2
Lawrance, R.A.3
-
8
-
-
18544372620
-
A comprehensive linkage analysis for myocardial infarction and its related risk factors
-
Broeckel U, Hengstenberg C, Mayer B, et al. A comprehensive linkage analysis for myocardial infarction and its related risk factors. Nat Genet 2002;30:210-4.
-
(2002)
Nat Genet
, vol.30
, pp. 210-214
-
-
Broeckel, U.1
Hengstenberg, C.2
Mayer, B.3
-
9
-
-
20044382611
-
Distinct heritable patterns of angiographic coronary artery disease in families with myocardial infarction
-
Fischer M, Broeckel U, Holmer S, et al. Distinct heritable patterns of angiographic coronary artery disease in families with myocardial infarction. Circulation 2005;111:855-62.
-
(2005)
Circulation
, vol.111
, pp. 855-862
-
-
Fischer, M.1
Broeckel, U.2
Holmer, S.3
-
10
-
-
23844472247
-
KORA-gen - resource for population genetics, controls and a broad spectrum of disease phenotypes
-
Wichmann HE, Gieger C, Illig T. KORA-gen - resource for population genetics, controls and a broad spectrum of disease phenotypes. Gesundheitswesen 2005;67:Suppl 1:S26-S30.
-
(2005)
Gesundheitswesen
, vol.67
, Issue.SUPPL. 1
-
-
Wichmann, H.E.1
Gieger, C.2
Illig, T.3
-
11
-
-
1642295096
-
Assessing the probability that a positive report is false: An approach for molecular epidemiology studies
-
Wacholder S, Chanock S, Garcia-Closas M, El Ghormli L, Rothman N. Assessing the probability that a positive report is false: an approach for molecular epidemiology studies. J Natl Cancer Inst 2004;96:434-42.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 434-442
-
-
Wacholder, S.1
Chanock, S.2
Garcia-Closas, M.3
El Ghormli, L.4
Rothman, N.5
-
12
-
-
79959524146
-
A haplotype map of the human genome
-
International HapMap Consortium
-
International HapMap Consortium. A haplotype map of the human genome. Nature 2005;437:1299-320.
-
(2005)
Nature
, vol.437
, pp. 1299-1320
-
-
-
13
-
-
34249996115
-
A common allele on chromosome 9 associated with coronary heart disease
-
McPherson R, Pertsemlidis A, Kavaslar N, et al. A common allele on chromosome 9 associated with coronary heart disease. Science 2007;316:1488-91.
-
(2007)
Science
, vol.316
, pp. 1488-1491
-
-
McPherson, R.1
Pertsemlidis, A.2
Kavaslar, N.3
-
14
-
-
34250010480
-
A common variant on chromosome 9p21 affects the risk of myocardial infarction
-
Helgadottir A, Thorleifsson G, Manolescu A, et al. A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science 2007;316:1491-3.
-
(2007)
Science
, vol.316
, pp. 1491-1493
-
-
Helgadottir, A.1
Thorleifsson, G.2
Manolescu, A.3
-
15
-
-
0037309326
-
Tumor suppression by Ink4a-Arf: Progress and puzzles
-
Lowe SW, Sherr CJ. Tumor suppression by Ink4a-Arf: progress and puzzles. Curr Opin Genet Dev 2003;13:77-83.
-
(2003)
Curr Opin Genet Dev
, vol.13
, pp. 77-83
-
-
Lowe, S.W.1
Sherr, C.J.2
-
16
-
-
0028168242
-
p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest
-
Hannon GJ, Beach D. p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest. Nature 1994;371:257-61.
-
(1994)
Nature
, vol.371
, pp. 257-261
-
-
Hannon, G.J.1
Beach, D.2
-
17
-
-
3943049366
-
Smad expression in human atherosclerotic lesions: Evidence for impaired TGFbeta/Smad signaling in smooth muscle cells of fibrofatty lesions
-
Kalinina N, Agrotis A, Antropova Y, et al. Smad expression in human atherosclerotic lesions: evidence for impaired TGFbeta/Smad signaling in smooth muscle cells of fibrofatty lesions. Arterioscler Thromb Vasc Biol 2004;24:1391-6.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 1391-1396
-
-
Kalinina, N.1
Agrotis, A.2
Antropova, Y.3
-
18
-
-
34249885875
-
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants
-
Scott LJ, Mohlke KL, Bonnycastle LL, et al. A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 2007;316:1341-5.
-
(2007)
Science
, vol.316
, pp. 1341-1345
-
-
Scott, L.J.1
Mohlke, K.L.2
Bonnycastle, L.L.3
-
19
-
-
34249895023
-
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
-
Zeggini E, Weedon MN, Lindgren CM, et al. Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 2007;316:1336-41.
-
(2007)
Science
, vol.316
, pp. 1336-1341
-
-
Zeggini, E.1
Weedon, M.N.2
Lindgren, C.M.3
-
20
-
-
34249888775
-
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
-
Saxena R, Voight BF, Lyssenko V, et al. Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 2007;316:1331-6.
-
(2007)
Science
, vol.316
, pp. 1331-1336
-
-
Saxena, R.1
Voight, B.F.2
Lyssenko, V.3
-
21
-
-
0242353316
-
Human mitochondrial C1-tetrahydrofolate synthase: Gene structure, tissue distribution of the mRNA, and immunolocalization in Chinese hamster ovary calls
-
Prasannan P, Pike S, Peng K, Shane B, Appling DR. Human mitochondrial C1-tetrahydrofolate synthase: gene structure, tissue distribution of the mRNA, and immunolocalization in Chinese hamster ovary calls. J Biol Chem 2003;278:43178-87.
-
(2003)
J Biol Chem
, vol.278
, pp. 43178-43187
-
-
Prasannan, P.1
Pike, S.2
Peng, K.3
Shane, B.4
Appling, D.R.5
-
22
-
-
26844566507
-
Enzymatic characterization of human mitochondrial C1-tetrahydrofolate synthase
-
Walkup AS, Appling DR. Enzymatic characterization of human mitochondrial C1-tetrahydrofolate synthase. Arch Biochem Biophys 2005;442:196-205.
-
(2005)
Arch Biochem Biophys
, vol.442
, pp. 196-205
-
-
Walkup, A.S.1
Appling, D.R.2
-
23
-
-
0033913983
-
Three siblings with nonketotic hyperglycinaemia, mildly elevated plasma homocysteine concentrations and moderate methylmalonic aciduria
-
Randak C, Roschinger W, Rolinski B, Hadorn HB, Applegarth DA, Roscher AA. Three siblings with nonketotic hyperglycinaemia, mildly elevated plasma homocysteine concentrations and moderate methylmalonic aciduria. J Inherit Metab Dis 2000;23:520-2.
-
(2000)
J Inherit Metab Dis
, vol.23
, pp. 520-522
-
-
Randak, C.1
Roschinger, W.2
Rolinski, B.3
Hadorn, H.B.4
Applegarth, D.A.5
Roscher, A.A.6
-
24
-
-
2942714933
-
-
Fruchart JC, Nierman MC, Stroes ES, Kastelein JJ, Duriez P. New risk factors for atherosclerosis and patient risk assessment. Circulation 2004;109:Suppl I:III-15-III-9.
-
Fruchart JC, Nierman MC, Stroes ES, Kastelein JJ, Duriez P. New risk factors for atherosclerosis and patient risk assessment. Circulation 2004;109:Suppl I:III-15-III-9.
-
-
-
-
25
-
-
23244463732
-
Genetic analysis of the interleukin-18 system highlights the role of the interleukin-18 gene in cardiovascular disease
-
Tiret L, Godefroy T, Lubos E, et al. Genetic analysis of the interleukin-18 system highlights the role of the interleukin-18 gene in cardiovascular disease. Circulation 2005;112:643-50.
-
(2005)
Circulation
, vol.112
, pp. 643-650
-
-
Tiret, L.1
Godefroy, T.2
Lubos, E.3
-
26
-
-
0033576656
-
Identification of a novel mouse p53 target gene DDA3
-
Lo PK, Chen JY, Lo WC, et al. Identification of a novel mouse p53 target gene DDA3. Oncogene 1999;18:7765-74.
-
(1999)
Oncogene
, vol.18
, pp. 7765-7774
-
-
Lo, P.K.1
Chen, J.Y.2
Lo, W.C.3
-
27
-
-
0036159908
-
Expression, function and clinical relevance of MIA (melanoma inhibitory activity)
-
Bosserhoff AK, Buettner R. Expression, function and clinical relevance of MIA (melanoma inhibitory activity). Histol Histopathol 2002;17:289-300.
-
(2002)
Histol Histopathol
, vol.17
, pp. 289-300
-
-
Bosserhoff, A.K.1
Buettner, R.2
-
28
-
-
0036682952
-
Smad3 allostery links TGF-beta receptor kinase activation to transcriptional control
-
Qin BY, Lam SS, Correia JJ, Lin K. Smad3 allostery links TGF-beta receptor kinase activation to transcriptional control. Genes Dev 2002;16:1950-63.
-
(2002)
Genes Dev
, vol.16
, pp. 1950-1963
-
-
Qin, B.Y.1
Lam, S.S.2
Correia, J.J.3
Lin, K.4
-
29
-
-
0034030142
-
TGF-beta signaling by Smad proteins
-
Miyazono K. TGF-beta signaling by Smad proteins. Cytokine Growth Factor Rev 2000;11:15-22.
-
(2000)
Cytokine Growth Factor Rev
, vol.11
, pp. 15-22
-
-
Miyazono, K.1
-
30
-
-
21544467275
-
Pathophysiology of coronary artery disease
-
Libby P, Theroux P. Pathophysiology of coronary artery disease. Circulation 2005;111:3481-8.
-
(2005)
Circulation
, vol.111
, pp. 3481-3488
-
-
Libby, P.1
Theroux, P.2
-
31
-
-
0029741063
-
The future of genetic studies of complex human diseases
-
Risch N, Merikangas K. The future of genetic studies of complex human diseases. Science 1996;273:1516-7.
-
(1996)
Science
, vol.273
, pp. 1516-1517
-
-
Risch, N.1
Merikangas, K.2
-
32
-
-
34247144499
-
Nonvalidation of reported genetic risk factors for acute coronary syndrome in a large-scale replication study
-
Morgan TM, Krumholz HM, Lifton RP, Spertus JA. Nonvalidation of reported genetic risk factors for acute coronary syndrome in a large-scale replication study. JAMA 2007;297:1551-61.
-
(2007)
JAMA
, vol.297
, pp. 1551-1561
-
-
Morgan, T.M.1
Krumholz, H.M.2
Lifton, R.P.3
Spertus, J.A.4
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