메뉴 건너뛰기




Volumn 17, Issue 3, 2016, Pages 146-159

Cheating evolution: Engineering gene drives to manipulate the fate of wild populations

Author keywords

[No Author keywords available]

Indexed keywords

ENDONUCLEASE; GUIDE RNA; NUCLEASE; SYNTHETIC DNA;

EID: 84958617028     PISSN: 14710056     EISSN: 14710064     Source Type: Journal    
DOI: 10.1038/nrg.2015.34     Document Type: Review
Times cited : (329)

References (148)
  • 1
    • 0014431860 scopus 로고
    • Possible use of translocations to fix desirable genes in insect pest populations
    • Curtis, C. F. Possible use of translocations to fix desirable genes in insect pest populations. Nature 218, 368-369 (1968).
    • (1968) Nature , vol.218 , pp. 368-369
    • Curtis, C.F.1
  • 2
    • 0014219333 scopus 로고
    • Extraordinary sex ratios A sex-ratio theory for sex linkage and inbreeding has new implications in cytogenetics and entomology
    • Hamilton, W. D. Extraordinary sex ratios. A sex-ratio theory for sex linkage and inbreeding has new implications in cytogenetics and entomology. Science 156, 477-488 (1967).
    • (1967) Science , vol.156 , pp. 477-488
    • Hamilton, W.D.1
  • 3
    • 0001700989 scopus 로고
    • On the possibility of a new method for the control of insect pests
    • Serebrovskii, A. S. On the possibility of a new method for the control of insect pests. Zool. Zhurnal 19, 618-630 (1940).
    • (1940) Zool. Zhurnal , vol.19 , pp. 618-630
    • Serebrovskii, A.S.1
  • 4
    • 0038027293 scopus 로고    scopus 로고
    • Site-specific selfish genes as tools for the control and genetic engineering of natural populations
    • Burt, A. Site-specific selfish genes as tools for the control and genetic engineering of natural populations. Proc. Biol. Sci. 270, 921-928 (2003).
    • (2003) Proc. Biol. Sci , vol.270 , pp. 921-928
    • Burt, A.1
  • 5
    • 34047222214 scopus 로고    scopus 로고
    • Introducing desirable transgenes into insect populations using y linked meiotic drive - A theoretical assessment
    • Huang, Y., Magori, K., Lloyd, A. L. & Gould, F. Introducing desirable transgenes into insect populations using Y linked meiotic drive - a theoretical assessment. Evolution 61, 717-726 (2007).
    • (2007) Evolution , vol.61 , pp. 717-726
    • Huang, Y.1    Magori, K.2    Lloyd, A.L.3    Gould, F.4
  • 6
    • 84919399288 scopus 로고    scopus 로고
    • Emergency department management of mosquito-borne illness: Malaria, dengue, and West Nile virus
    • Caraballo, H. & King, K. Emergency department management of mosquito-borne illness: malaria, dengue, and West Nile virus. Emerg. Med. Pract. 16, 1-23 (2014).
    • (2014) Emerg. Med. Pract , vol.16 , pp. 1-23
    • Caraballo, H.1    King, K.2
  • 7
    • 84911411766 scopus 로고    scopus 로고
    • Challenges of drug-resistant malaria
    • Sinha, S., Medhi, B. & Sehgal, R. Challenges of drug-resistant malaria. Parasite 21, 61 (2014).
    • (2014) Parasite , vol.21 , pp. 61
    • Sinha, S.1    Medhi, B.2    Sehgal, R.3
  • 8
    • 0012433587 scopus 로고    scopus 로고
    • World Health Organization [online]
    • World Health Organization. Malaria. World Health Organization [online], http: //www.who.int/mediacentre/ factsheets/fs094/en/ (2015).
    • (2015) World Health Organization. Malaria
  • 9
    • 84900302189 scopus 로고    scopus 로고
    • Heritable strategies for controlling insect vectors of disease
    • Burt, A. Heritable strategies for controlling insect vectors of disease. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 369, 20130432 (2014).
    • (2014) Philos. Trans. R. Soc. Lond. B. Biol. Sci , vol.369 , pp. 20130432
    • Burt, A.1
  • 10
    • 33646882131 scopus 로고    scopus 로고
    • Gene drive systems for insect disease vectors
    • Sinkins, S. P. & Gould, F. Gene drive systems for insect disease vectors. Nat. Rev. Genet. 7, 427-435 (2006).
    • (2006) Nat. Rev. Genet , vol.7 , pp. 427-435
    • Sinkins, S.P.1    Gould, F.2
  • 11
    • 84891955591 scopus 로고    scopus 로고
    • Genetic control of mosquitoes
    • Alphey, L. Genetic control of mosquitoes. Annu. Rev. Entomol. 59, 205-224 (2014).
    • (2014) Annu. Rev. Entomol , vol.59 , pp. 205-224
    • Alphey, L.1
  • 12
    • 84879534242 scopus 로고    scopus 로고
    • Genetic control of Aedes mosquitoes
    • Alphey, L., et al. Genetic control of Aedes mosquitoes. Pathog. Glob. Health 107, 170-179 (2013).
    • (2013) Pathog. Glob. Health , vol.107 , pp. 170-179
    • Alphey, L.1
  • 13
    • 79960634800 scopus 로고    scopus 로고
    • Selfish genetic elements, genetic conflict, and evolutionary innovation
    • Werren, J. H. Selfish genetic elements, genetic conflict, and evolutionary innovation. Proc. Natl Acad. Sci. USA 108 (Suppl. 2), 10863-10870 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 10863-10870
    • Werren, J.H.1
  • 14
    • 0035432062 scopus 로고    scopus 로고
    • The role of selfish genetic elements in eukaryotic evolution
    • Hurst, G. D. & Werren, J. H. The role of selfish genetic elements in eukaryotic evolution. Nat. Rev. Genet. 2, 597-606 (2001).
    • (2001) Nat. Rev. Genet , vol.2 , pp. 597-606
    • Hurst, G.D.1    Werren, J.H.2
  • 17
    • 84928208828 scopus 로고    scopus 로고
    • Genome editing the mutagenic chain reaction: A method for converting heterozygous to homozygous mutations
    • Gantz, V. M. & Bier, E. Genome editing. The mutagenic chain reaction: a method for converting heterozygous to homozygous mutations. Science 348, 442-444 (2015).
    • (2015) Science , vol.348 , pp. 442-444
    • Gantz, V.M.1    Bier, E.2
  • 18
    • 84876769853 scopus 로고    scopus 로고
    • A synthetic gene drive system for local, reversible modification and suppression of insect populations
    • Akbari, O. S., et al. A synthetic gene drive system for local, reversible modification and suppression of insect populations. Curr. Biol. 23, 671-677 (2013).
    • (2013) Curr. Biol , vol.23 , pp. 671-677
    • Akbari, O.S.1
  • 19
    • 34247610283 scopus 로고    scopus 로고
    • A synthetic maternal-effect selfish genetic element drives population replacement in Drosophila
    • Chen, C. H., et al. A synthetic maternal-effect selfish genetic element drives population replacement in Drosophila. Science 316, 597-600 (2007).
    • (2007) Science , vol.316 , pp. 597-600
    • Chen, C.H.1
  • 20
    • 84919639905 scopus 로고    scopus 로고
    • Novel synthetic Medea selfish genetic elements drive population replacement in Drosophila; A theoretical exploration of Medea-dependent population suppression
    • Akbari, O. S., et al. Novel synthetic Medea selfish genetic elements drive population replacement in Drosophila; a theoretical exploration of Medea-dependent population suppression. ACS Synth. Biol. 3, 915-928 (2014).
    • (2014) ACS Synth. Biol , vol.3 , pp. 915-928
    • Akbari, O.S.1
  • 21
    • 84949220605 scopus 로고    scopus 로고
    • Highly efficient Cas9 mediated gene drive for population modification of the malaria vector mosquito Anopheles stephensi
    • Gantz, V. M., et al. Highly efficient Cas9 mediated gene drive for population modification of the malaria vector mosquito Anopheles stephensi. Proc. Natl Acad. Sci. USA 112, E6736-E6743 (2015).
    • (2015) Proc. Natl Acad. Sci. USA , vol.112 , pp. E6736-E6743
    • Gantz, V.M.1
  • 22
    • 84953730637 scopus 로고    scopus 로고
    • A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae
    • Hammond, A., et al. A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae. Nat. Biotechnol. 34, 78-83 (2016).
    • (2016) Nat. Biotechnol , vol.34 , pp. 78-83
    • Hammond, A.1
  • 23
    • 84884856342 scopus 로고    scopus 로고
    • Cas9 as a versatile tool for engineering biology
    • Mali, P., Esvelt, K. M. & Church, G. M. Cas9 as a versatile tool for engineering biology. Nat. Methods 10, 957-963 (2013).
    • (2013) Nat. Methods , vol.10 , pp. 957-963
    • Mali, P.1    Esvelt, K.M.2    Church, G.M.3
  • 24
    • 84883785822 scopus 로고    scopus 로고
    • Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9
    • Li, J. F., et al. Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9. Nat. Biotechnol. 31, 688-691 (2013).
    • (2013) Nat. Biotechnol , vol.31 , pp. 688-691
    • Li, J.F.1
  • 25
    • 84887109827 scopus 로고    scopus 로고
    • Exciting prospects for precise engineering of Caenorhabditis elegans genomes with CRISPR/Cas9
    • Frokjaer-Jensen, C. Exciting prospects for precise engineering of Caenorhabditis elegans genomes with CRISPR/Cas9. Genetics 195, 635-642 (2013).
    • (2013) Genetics , vol.195 , pp. 635-642
    • Frokjaer-Jensen, C.1
  • 26
    • 84880088705 scopus 로고    scopus 로고
    • Genome engineering of Drosophila with the CRISPR RNA-guided Cas9 nuclease
    • Gratz, S. J., et al. Genome engineering of Drosophila with the CRISPR RNA-guided Cas9 nuclease. Genetics 194, 1029-1035 (2013).
    • (2013) Genetics , vol.194 , pp. 1029-1035
    • Gratz, S.J.1
  • 27
    • 84926051661 scopus 로고    scopus 로고
    • Silencing of end-joining repair for efficient site-specific gene insertion after TALEN/ CRISPR mutagenesis in Aedes aegypti
    • Basu, S., et al. Silencing of end-joining repair for efficient site-specific gene insertion after TALEN/ CRISPR mutagenesis in Aedes aegypti. Proc. Natl Acad. Sci. USA 112, 4038-4043 (2015).
    • (2015) Proc. Natl Acad. Sci. USA , vol.112 , pp. 4038-4043
    • Basu, S.1
  • 28
    • 84927695100 scopus 로고    scopus 로고
    • Genome engineering with CRISPR-Cas9 in the mosquito Aedes aegypti
    • Kistler, K. E., Vosshall, L. B. & Matthews, B. J. Genome engineering with CRISPR-Cas9 in the mosquito Aedes aegypti. Cell Rep. 11, 51-60 (2015).
    • (2015) Cell Rep , vol.11 , pp. 51-60
    • Kistler, K.E.1    Vosshall, L.B.2    Matthews, B.J.3
  • 29
    • 84874617789 scopus 로고    scopus 로고
    • Efficient genome editing in zebrafish using a CRISPR-Cas system
    • Hwang, W. Y., et al. Efficient genome editing in zebrafish using a CRISPR-Cas system. Nat. Biotechnol. 31, 227-229 (2013).
    • (2013) Nat. Biotechnol , vol.31 , pp. 227-229
    • Hwang, W.Y.1
  • 30
    • 84877103949 scopus 로고    scopus 로고
    • Generation of gene-modified mice via Cas9/RNA-mediated gene targeting
    • Shen, B., et al. Generation of gene-modified mice via Cas9/RNA-mediated gene targeting. Cell Res. 23, 720-723 (2013).
    • (2013) Cell Res , vol.23 , pp. 720-723
    • Shen, B.1
  • 31
    • 84894081986 scopus 로고    scopus 로고
    • Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos
    • Niu, Y., et al. Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos. Cell 156, 836-843 (2014).
    • (2014) Cell , vol.156 , pp. 836-843
    • Niu, Y.1
  • 32
    • 84873729095 scopus 로고    scopus 로고
    • Multiplex genome engineering using CRISPR/Cas systems
    • Cong, L., et al. Multiplex genome engineering using CRISPR/Cas systems. Science 339, 819-823 (2013).
    • (2013) Science , vol.339 , pp. 819-823
    • Cong, L.1
  • 33
    • 84913568580 scopus 로고    scopus 로고
    • Programmable RNA recognition and cleavage by CRISPR/Cas9
    • O'Connell, M. R., et al. Programmable RNA recognition and cleavage by CRISPR/Cas9. Nature 516, 263-266 (2014).
    • (2014) Nature , vol.516 , pp. 263-266
    • O'Connell, M.R.1
  • 35
    • 84897546295 scopus 로고    scopus 로고
    • Self-processing of ribozyme-flanked RNAs into guide RNAs in vitro and in vivo for CRISPR-mediated genome editing
    • Gao, Y. & Zhao, Y. Self-processing of ribozyme-flanked RNAs into guide RNAs in vitro and in vivo for CRISPR-mediated genome editing. J. Integr. Plant Biol. 56, 343-349 (2014).
    • (2014) J. Integr. Plant Biol , vol.56 , pp. 343-349
    • Gao, Y.1    Zhao, Y.2
  • 36
    • 84925262435 scopus 로고    scopus 로고
    • Boosting CRISPR/ Cas9 multiplex editing capability with the endogenous tRNA-processing system
    • Xie, K., Minkenberg, B. & Yang, Y. Boosting CRISPR/ Cas9 multiplex editing capability with the endogenous tRNA-processing system. Proc. Natl Acad. Sci. USA 112, 3570-3575 (2015).
    • (2015) Proc. Natl Acad. Sci. USA , vol.112 , pp. 3570-3575
    • Xie, K.1    Minkenberg, B.2    Yang, Y.3
  • 37
    • 84903549014 scopus 로고    scopus 로고
    • Sgrnacas9: A software package for designing CRISPR sgRNA and evaluating potential off-target cleavage sites
    • Xie, S. Shen, B., Zhang, C., Huang, X. & Zhang, Y. sgRNAcas9: a software package for designing CRISPR sgRNA and evaluating potential off-target cleavage sites. PLoS ONE 9, e100448 (2014).
    • (2014) PLoS ONE , vol.9 , pp. e100448
    • Xie Shen S, B.1    Zhang, C.2    Huang, X.3    Zhang, Y.4
  • 38
    • 84975678715 scopus 로고    scopus 로고
    • Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas System
    • Zetsche, B., et al. Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas System. Cell 163, 759-771 (2015).
    • (2015) Cell , vol.163 , pp. 759-771
    • Zetsche, B.1
  • 39
    • 84958633469 scopus 로고    scopus 로고
    • Evolutionary decay and the prospects for long-term disease intervention using engineered insect vectors
    • Bull, J. J. Evolutionary decay and the prospects for long-term disease intervention using engineered insect vectors. Evol. Med. Publ. Health 2015, 152-166 (2015).
    • (2015) Evol. Med. Publ. Health , vol.2015 , pp. 152-166
    • Bull, J.J.1
  • 40
    • 84940502877 scopus 로고    scopus 로고
    • Safeguarding gene drive experiments in the laboratory
    • Akbari, O. S., et al. Safeguarding gene drive experiments in the laboratory. Science 349, 927-929 (2015).
    • (2015) Science , vol.349 , pp. 927-929
    • Akbari, O.S.1
  • 41
    • 84905914560 scopus 로고    scopus 로고
    • Biotechnology. Regulating gene drives
    • Oye, K. A., et al. Biotechnology. Regulating gene drives. Science 345, 626-628 (2014).
    • (2014) Science , vol.345 , pp. 626-628
    • Oye, K.A.1
  • 42
    • 78651240053 scopus 로고    scopus 로고
    • Homing endonucleases: From microbial genetic invaders to reagents for targeted DNA modification
    • Stoddard, B. L. Homing endonucleases: from microbial genetic invaders to reagents for targeted DNA modification. Structure 19, 7-15 (2011).
    • (2011) Structure , vol.19 , pp. 7-15
    • Stoddard, B.L.1
  • 43
    • 80055066227 scopus 로고    scopus 로고
    • Requirements for effective malaria control with homing endonuclease genes
    • Deredec, A., Godfray, H. C. & Burt, A. Requirements for effective malaria control with homing endonuclease genes. Proc. Natl Acad. Sci. USA 108, E874-E880 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. E874-E880
    • Deredec, A.1    Godfray, H.C.2    Burt, A.3
  • 44
    • 55749111397 scopus 로고    scopus 로고
    • The population genetics of using homing endonuclease genes in vector and pest management
    • Deredec, A., Burt, A. & Godfray, H. C. The population genetics of using homing endonuclease genes in vector and pest management. Genetics 179, 2013-2026 (2008).
    • (2008) Genetics , vol.179 , pp. 2013-2026
    • Deredec, A.1    Burt, A.2    Godfray, H.C.3
  • 45
    • 84890859516 scopus 로고    scopus 로고
    • Modelling the spatial spread of a homing endonuclease gene in a mosquito population
    • North, A., Burt, A., Godfray, H. C. & Buckley, Y. Modelling the spatial spread of a homing endonuclease gene in a mosquito population. J. Appl. Ecol. 50, 1216-1225 (2013).
    • (2013) J. Appl. Ecol , vol.50 , pp. 1216-1225
    • North, A.1    Burt, A.2    Godfray, H.C.3    Buckley, Y.4
  • 46
    • 84943602261 scopus 로고    scopus 로고
    • Modeling the manipulation of natural populations by the mutagenic chain reaction
    • Unckless, R. L., Messer, P. W., Connallon, T. & Clark, A. G. Modeling the manipulation of natural populations by the mutagenic chain reaction. Genetics 201, 425-431 (2015).
    • (2015) Genetics , vol.201 , pp. 425-431
    • Unckless, R.L.1    Messer, P.W.2    Connallon, T.3    Clark, A.G.4
  • 47
    • 84896934810 scopus 로고    scopus 로고
    • Interplay of population genetics and dynamics in the genetic control of mosquitoes
    • Alphey, N. & Bonsall, M. B. Interplay of population genetics and dynamics in the genetic control of mosquitoes. J. R. Soc. Interface 11, 20131071 (2014).
    • (2014) J. R. Soc. Interface , vol.11 , pp. 20131071
    • Alphey, N.1    Bonsall, M.B.2
  • 48
    • 84956762535 scopus 로고    scopus 로고
    • The dawn of active genetics
    • Gantz, V. M. & Bier, E. The dawn of active genetics. Bioessays 38, 50-63 (2016).
    • (2016) Bioessays , vol.38 , pp. 50-63
    • Gantz, V.M.1    Bier, E.2
  • 49
    • 84924410016 scopus 로고    scopus 로고
    • Concerning RNA-guided gene drives for the alteration of wild populations
    • Esvelt, K. M., Smidler, A. L., Catteruccia, F. & Church, G. M. Concerning RNA-guided gene drives for the alteration of wild populations. eLife 3, e03401 (2014).
    • (2014) ELife , vol.3 , pp. e03401
    • Esvelt, K.M.1    Smidler, A.L.2    Catteruccia, F.3    Church, G.M.4
  • 50
    • 79955922770 scopus 로고    scopus 로고
    • A synthetic homing endonuclease-based gene drive system in the human malaria mosquito
    • Windbichler, N., et al. A synthetic homing endonuclease-based gene drive system in the human malaria mosquito. Nature 473, 212-215 (2011).
    • (2011) Nature , vol.473 , pp. 212-215
    • Windbichler, N.1
  • 51
    • 34848885878 scopus 로고    scopus 로고
    • Homing endonuclease mediated gene targeting in Anopheles gambiae cells and embryos
    • Windbichler, N., et al. Homing endonuclease mediated gene targeting in Anopheles gambiae cells and embryos. Nucleic Acids Res. 35, 5922-5933 (2007).
    • (2007) Nucleic Acids Res , vol.35 , pp. 5922-5933
    • Windbichler, N.1
  • 52
    • 84872550050 scopus 로고    scopus 로고
    • Optimising homing endonuclease gene drive performance in a semi-refractory species: The Drosophila melanogaster experience
    • Chan, Y. S., Huen, D. S., Glauert, R., Whiteway, E. & Russell, S. Optimising homing endonuclease gene drive performance in a semi-refractory species: the Drosophila melanogaster experience. PLoS ONE 8, e54130 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e54130
    • Chan, Y.S.1    Huen, D.S.2    Glauert, R.3    Whiteway, E.4    Russell, S.5
  • 53
    • 79955939676 scopus 로고    scopus 로고
    • Insect population control by homing endonuclease-based gene drive: An evaluation in Drosophila melanogaster
    • Chan, Y. S., Naujoks, D. A., Huen, D. S. & Russell, S. Insect population control by homing endonuclease-based gene drive: an evaluation in Drosophila melanogaster. Genetics 188, 33-44 (2011).
    • (2011) Genetics , vol.188 , pp. 33-44
    • Chan, Y.S.1    Naujoks, D.A.2    Huen, D.S.3    Russell, S.4
  • 54
    • 84883808451 scopus 로고    scopus 로고
    • The design and in vivo evaluation of engineered i OnuI-based enzymes for HEG gene drive
    • Chan, Y. S., et al. The design and in vivo evaluation of engineered I OnuI-based enzymes for HEG gene drive. PLoS ONE 8, e74254 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e74254
    • Chan, Y.S.1
  • 55
    • 84903196074 scopus 로고    scopus 로고
    • Development of synthetic selfish elements based on modular nucleases in Drosophila melanogaster
    • Simoni, A., et al. Development of synthetic selfish elements based on modular nucleases in Drosophila melanogaster. Nucleic Acids Res. 42, 7461-7472 (2014).
    • (2014) Nucleic Acids Res , vol.42 , pp. 7461-7472
    • Simoni, A.1
  • 56
    • 84865070369 scopus 로고    scopus 로고
    • A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity
    • Jinek, M., et al. A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 337, 816-821 (2012).
    • (2012) Science , vol.337 , pp. 816-821
    • Jinek, M.1
  • 57
    • 84903516238 scopus 로고    scopus 로고
    • Microhomology-based choice of Cas9 nuclease target sites
    • Bae, S., Kweon, J., Kim, H. S. & Kim, J. S. Microhomology-based choice of Cas9 nuclease target sites. Nat. Methods 11, 705-706 (2014).
    • (2014) Nat. Methods , vol.11 , pp. 705-706
    • Bae, S.1    Kweon, J.2    Kim, H.S.3    Kim, J.S.4
  • 58
    • 84915826227 scopus 로고    scopus 로고
    • Identification of germline transcriptional regulatory elements in Aedes aegypti
    • Akbari, O. S., Papathanos, P. A., Sandler, J. E., Kennedy, K. & Hay, B. A. Identification of germline transcriptional regulatory elements in Aedes aegypti. Sci. Rep. 4, 3954 (2014).
    • (2014) Sci. Rep , vol.4 , pp. 3954
    • Akbari, O.S.1    Papathanos, P.A.2    Sandler, J.E.3    Kennedy, K.4    Hay, B.A.5
  • 60
    • 84929147435 scopus 로고    scopus 로고
    • Increasing the efficiency of homology-directed repair for CRISPR-Cas9 induced precise gene editing in mammalian cells
    • Chu, V. T., et al. Increasing the efficiency of homology-directed repair for CRISPR-Cas9 induced precise gene editing in mammalian cells. Nat. Biotechnol. 33, 543-548 (2015).
    • (2015) Nat. Biotechnol , vol.33 , pp. 543-548
    • Chu, V.T.1
  • 61
    • 84896308706 scopus 로고    scopus 로고
    • Cas-OFFinder: A fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases
    • Bae, S., Park, J. & Kim, J. S. Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases. Bioinformatics 30, 1473-1475 (2014).
    • (2014) Bioinformatics , vol.30 , pp. 1473-1475
    • Bae, S.1    Park, J.2    Kim, J.S.3
  • 62
    • 84923266604 scopus 로고    scopus 로고
    • GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
    • Tsai, S. Q., et al. GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases. Nat. Biotechnol. 33, 187-197 (2015).
    • (2015) Nat. Biotechnol , vol.33 , pp. 187-197
    • Tsai, S.Q.1
  • 63
    • 84937764361 scopus 로고    scopus 로고
    • Small molecule-triggered Cas9 protein with improved genome-editing specificity
    • Davis, K. M., Pattanayak, V., Thompson, D. B., Zuris, J. A. & Liu, D. R. Small molecule-triggered Cas9 protein with improved genome-editing specificity. Nat. Chem. Biol. 11, 316-318 (2015).
    • (2015) Nat. Chem. Biol , vol.11 , pp. 316-318
    • Davis, K.M.1    Pattanayak, V.2    Thompson, D.B.3    Zuris, J.A.4    Liu, D.R.5
  • 64
    • 84952943845 scopus 로고    scopus 로고
    • Rationally engineered Cas9 nucleases with improved specificity
    • Slaymaker, I. M., et al. Rationally engineered Cas9 nucleases with improved specificity. Science 351, 84-88 (2015).
    • (2015) Science , vol.351 , pp. 84-88
    • Slaymaker, I.M.1
  • 65
    • 0027286134 scopus 로고
    • Cheaters sometimes prosper: Distortion of mendelian segregation by meiotic drive
    • Lyttle, T. W. Cheaters sometimes prosper: distortion of mendelian segregation by meiotic drive. Trends Genet. 9, 205-210 (1993).
    • (1993) Trends Genet , vol.9 , pp. 205-210
    • Lyttle, T.W.1
  • 67
    • 0001168114 scopus 로고
    • Sex-ratio distortion caused by meiotic drive in mosquitoes
    • Wood, R. J. & Newton, M. E. Sex-ratio distortion caused by meiotic drive in mosquitoes. Am. Naturalist 137, 379-391 (1991).
    • (1991) Am. Naturalist , vol.137 , pp. 379-391
    • Wood, R.J.1    Newton, M.E.2
  • 69
    • 0040150333 scopus 로고
    • An inherited male-producing factor in Aedes aegypti
    • Craig, G. B. Jr., Hickey, W. A. & Vandehey, R. C. An inherited male-producing factor in Aedes aegypti. Science 132, 1887-1889 (1960).
    • (1960) Science , vol.132 , pp. 1887-1889
    • Craig, G.B.1    Hickey, W.A.2    Vandehey, R.C.3
  • 70
    • 0013915357 scopus 로고
    • Distortion of sex ratio in populations of Aedes aegypti
    • Hickey, W. A. & Craig, G. B. Jr. Distortion of sex ratio in populations of Aedes aegypti. Can. J. Genet. Cytol. 8, 260-278 (1966).
    • (1966) Can. J. Genet. Cytol , vol.8 , pp. 260-278
    • Hickey, W.A.1    Craig, G.B.2
  • 71
    • 0017704096 scopus 로고
    • Experimental population genetics of meiotic drive systems i Pseudo y chromosomal drive as a means of eliminating cage populations of Drosophila melanogaster
    • Lyttle, T. W. Experimental population genetics of meiotic drive systems. I. Pseudo Y chromosomal drive as a means of eliminating cage populations of Drosophila melanogaster. Genetics 86, 413-445 (1977).
    • (1977) Genetics , vol.86 , pp. 413-445
    • Lyttle, T.W.1
  • 72
    • 0017149598 scopus 로고
    • A cytogenetic analysis of meiotic drive in the mosquito Aedes aegypti (L)
    • Newton, M. E., Wood, R. J. & Southern, D. I. A cytogenetic analysis of meiotic drive in the mosquito, Aedes aegypti (L.). Genetica 46, 297-318 (1976).
    • (1976) Genetica , vol.46 , pp. 297-318
    • Newton, M.E.1    Wood, R.J.2    Southern, D.I.3
  • 73
    • 84934435952 scopus 로고    scopus 로고
    • Insect population suppression using engineered insects
    • Alphey, L., Nimmo, D., O'Connell, S. & Alphey, N. Insect population suppression using engineered insects. Adv. Exp. Med. Biol. 627, 93-103 (2008).
    • (2008) Adv. Exp. Med. Biol , vol.627 , pp. 93-103
    • Alphey, L.1    Nimmo, D.2    O'Connell, S.3    Alphey, N.4
  • 74
    • 84864040644 scopus 로고    scopus 로고
    • Infertility resulting from transgenic i PpoI male Anopheles gambiae in large cage trials
    • Klein, T. A., Windbichler, N., Deredec, A., Burt, A. & Benedict, M. Q. Infertility resulting from transgenic I PpoI male Anopheles gambiae in large cage trials. Pathog. Glob. Health 106, 20-31 (2012).
    • (2012) Pathog. Glob. Health , vol.106 , pp. 20-31
    • Klein, T.A.1    Windbichler, N.2    Deredec, A.3    Burt, A.4    Benedict, M.Q.5
  • 75
    • 58149154657 scopus 로고    scopus 로고
    • Targeting the X chromosome during spermatogenesis induces y chromosome transmission ratio distortion and early dominant embryo lethality in Anopheles gambiae
    • Windbichler, N., Papathanos, P. A. & Crisanti, A. Targeting the X chromosome during spermatogenesis induces Y chromosome transmission ratio distortion and early dominant embryo lethality in Anopheles gambiae. PLoS Genet. 4, e1000291 (2008).
    • (2008) PLoS Genet , vol.4 , pp. e1000291
    • Windbichler, N.1    Papathanos, P.A.2    Crisanti, A.3
  • 76
    • 84902140512 scopus 로고    scopus 로고
    • A synthetic sex ratio distortion system for the control of the human malaria mosquito
    • Galizi, R., et al. A synthetic sex ratio distortion system for the control of the human malaria mosquito. Nat. Commun. 5, 3977 (2014).
    • (2014) Nat. Commun , vol.5 , pp. 3977
    • Galizi, R.1
  • 77
    • 84901660045 scopus 로고    scopus 로고
    • Site-specific genetic engineering of the Anopheles gambiae y chromosome
    • Bernardini, F., et al. Site-specific genetic engineering of the Anopheles gambiae Y chromosome. Proc. Natl Acad. Sci. USA 111, 7600-7605 (2014).
    • (2014) Proc. Natl Acad. Sci. USA , vol.111 , pp. 7600-7605
    • Bernardini, F.1
  • 78
    • 0028113042 scopus 로고
    • The population dynamics of maternal-effect selfish genes
    • Wade, M. J. & Beeman, R. W. The population dynamics of maternal-effect selfish genes. Genetics 138, 1309-1314 (1994).
    • (1994) Genetics , vol.138 , pp. 1309-1314
    • Wade, M.J.1    Beeman, R.W.2
  • 79
    • 77955419009 scopus 로고    scopus 로고
    • Engineering the genomes of wild insect populations: Challenges, and opportunities provided by synthetic Medea selfish genetic elements
    • Hay, B. A., et al. Engineering the genomes of wild insect populations: challenges, and opportunities provided by synthetic Medea selfish genetic elements. J. Insect Physiol. 56, 1402-1413 (2010).
    • (2010) J. Insect Physiol , vol.56 , pp. 1402-1413
    • Hay, B.A.1
  • 80
    • 79953311871 scopus 로고    scopus 로고
    • Medea selfish genetic elements as tools for altering traits of wild populations: A theoretical analysis
    • Ward, C. M., et al. Medea selfish genetic elements as tools for altering traits of wild populations: a theoretical analysis. Evolution 65, 1149-1162 (2011).
    • (2011) Evolution , vol.65 , pp. 1149-1162
    • Ward, C.M.1
  • 81
    • 79957999218 scopus 로고    scopus 로고
    • Computer simulation on disease vector population replacement driven by the maternal effect dominant embryonic arrest
    • Guevara-Souza, M. & Vallejo, E. E. Computer simulation on disease vector population replacement driven by the maternal effect dominant embryonic arrest. Adv. Exp. Med. Biol. 696, 335-343 (2011).
    • (2011) Adv. Exp. Med. Biol , vol.696 , pp. 335-343
    • Guevara-Souza, M.1    Vallejo, E.E.2
  • 82
    • 77954253931 scopus 로고    scopus 로고
    • Gene-drive in age-structured insect populations
    • Huang, Y., Lloyd, A. L., Legros, M. & Gould, F. Gene-drive in age-structured insect populations. Evol. Appl. 2, 143-159 (2009).
    • (2009) Evol. Appl , vol.2 , pp. 143-159
    • Huang, Y.1    Lloyd, A.L.2    Legros, M.3    Gould, F.4
  • 83
    • 84892420898 scopus 로고    scopus 로고
    • Modeling the dynamics of a non-limited and a self-limited gene drive system in structured Aedes aegypti populations
    • Legros, M., et al. Modeling the dynamics of a non-limited and a self-limited gene drive system in structured Aedes aegypti populations. PLoS ONE 8, e83354 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e83354
    • Legros, M.1
  • 84
    • 81455149491 scopus 로고    scopus 로고
    • Stability properties of underdominance in finite subdivided populations
    • Altrock, P. M., Traulsen, A. & Reed, F. A. Stability properties of underdominance in finite subdivided populations. PLoS Comput. Biol. 7, e1002260 (2011).
    • (2011) PLoS Comput. Biol , vol.7 , pp. e1002260
    • Altrock, P.M.1    Traulsen, A.2    Reed, F.A.3
  • 85
    • 77955803263 scopus 로고    scopus 로고
    • Using underdominance to bi stably transform local populations
    • Altrock, P. M., Traulsen, A., Reeves, R. G. & Reed, F. A. Using underdominance to bi stably transform local populations. J. Theor. Biol. 267, 62-75 (2010).
    • (2010) J. Theor. Biol , vol.267 , pp. 62-75
    • Altrock, P.M.1    Traulsen, A.2    Reeves, R.G.3    Reed, F.A.4
  • 86
    • 33646190056 scopus 로고    scopus 로고
    • Genetically engineered underdominance for manipulation of pest populations: A deterministic model
    • Magori, K. & Gould, F. Genetically engineered underdominance for manipulation of pest populations: a deterministic model. Genetics 172, 2613-2620 (2006).
    • (2006) Genetics , vol.172 , pp. 2613-2620
    • Magori, K.1    Gould, F.2
  • 87
    • 0035823290 scopus 로고    scopus 로고
    • Engineered underdominance allows efficient and economical introgression of traits into pest populations
    • Davis, S., Bax, N. & Grewe, P. Engineered underdominance allows efficient and economical introgression of traits into pest populations. J. Theor. Biol. 212, 83-98 (2001).
    • (2001) J. Theor. Biol , vol.212 , pp. 83-98
    • Davis, S.1    Bax, N.2    Grewe, P.3
  • 88
    • 79954620912 scopus 로고    scopus 로고
    • Gene-drive into insect populations with age and spatial structure: A theoretical assessment
    • Huang, Y., Lloyd, A. L., Legros, M. & Gould, F. Gene-drive into insect populations with age and spatial structure: a theoretical assessment. Evol. Appl. 4, 415-428 (2011).
    • (2011) Evol. Appl , vol.4 , pp. 415-428
    • Huang, Y.1    Lloyd, A.L.2    Legros, M.3    Gould, F.4
  • 89
    • 0015524817 scopus 로고
    • Chromosome rearrangements for the control of insect pests
    • Foster, G. G., Whitten, M. J., Prout, T. & Gill, R. Chromosome rearrangements for the control of insect pests. Science 176, 875-880 (1972).
    • (1972) Science , vol.176 , pp. 875-880
    • Foster, G.G.1    Whitten, M.J.2    Prout, T.3    Gill, R.4
  • 91
    • 1042279437 scopus 로고    scopus 로고
    • Population genetics of autocidal control and strain replacement
    • Gould, F. & Schliekelman, P. Population genetics of autocidal control and strain replacement. Annu. Rev. Entomol. 49, 193-217 (2004).
    • (2004) Annu. Rev. Entomol , vol.49 , pp. 193-217
    • Gould, F.1    Schliekelman, P.2
  • 92
    • 0019376934 scopus 로고
    • Field studies of genetic control systems for mosquitoes
    • Asman, S. M., McDonald, P. T. & Prout, T. Field studies of genetic control systems for mosquitoes. Annu. Rev. Entomol. 26, 289-318 (1981
    • (1981) Annu. Rev. Entomol , vol.26 , pp. 289-318
    • Asman, S.M.1    McDonald, P.T.2    Prout, T.3
  • 93
    • 48749134300 scopus 로고
    • Chromosome rearrangements in the control of mosquitoes
    • Baker, R. H. Chromosome rearrangements in the control of mosquitoes. Prev. Vet. Med. 2, 529-540 (1984).
    • (1984) Prev. Vet. Med , vol.2 , pp. 529-540
    • Baker, R.H.1
  • 94
    • 0015526848 scopus 로고
    • Eradicating mosquitoes using translocations: A first field experiment
    • Laven, H., Cousserans, J. & Guille, G. Eradicating mosquitoes using translocations: a first field experiment. Nature 236, 456-457 (1972).
    • (1972) Nature , vol.236 , pp. 456-457
    • Laven, H.1    Cousserans, J.2    Guille, G.3
  • 95
    • 0016921725 scopus 로고
    • Progress in the use of chromosomal translocations for the control of insect pests
    • Robinson, A. S. Progress in the use of chromosomal translocations for the control of insect pests. Biol. Rev. Camb. Philos. Soc. 51, 1-24 (1976).
    • (1976) Biol. Rev. Camb. Philos. Soc , vol.51 , pp. 1-24
    • Robinson, A.S.1
  • 96
    • 84901329144 scopus 로고    scopus 로고
    • First steps towards underdominant genetic transformation of insect populations
    • Reeves, R. G., Bryk, J., Altrock, P. M., Denton, J. A. & Reed, F. A. First steps towards underdominant genetic transformation of insect populations. PLoS ONE 9, e97557 (2014).
    • (2014) PLoS ONE , vol.9 , pp. e97557
    • Reeves, R.G.1    Bryk, J.2    Altrock, P.M.3    Denton, J.A.4    Reed, F.A.5
  • 97
    • 3543111494 scopus 로고    scopus 로고
    • An efficient method to generate chromosomal rearrangements by targeted DNA double-strand breaks in Drosophila melanogaster
    • Egli, D., Hafen, E. & Schaffner, W. An efficient method to generate chromosomal rearrangements by targeted DNA double-strand breaks in Drosophila melanogaster. Genome Res. 14, 1382-1393 (2004).
    • (2004) Genome Res , vol.14 , pp. 1382-1393
    • Egli, D.1    Hafen, E.2    Schaffner, W.3
  • 98
    • 15544378698 scopus 로고    scopus 로고
    • Meiotic recombination in Drosophila females depends on chromosome continuity between genetically defined boundaries
    • Sherizen, D., Jang, J. K., Bhagat, R., Kato, N. & McKim, K. S. Meiotic recombination in Drosophila females depends on chromosome continuity between genetically defined boundaries. Genetics 169, 767-781 (2005).
    • (2005) Genetics , vol.169 , pp. 767-781
    • Sherizen, D.1    Jang, J.K.2    Bhagat, R.3    Kato, N.4    McKim, K.S.5
  • 99
    • 84901495795 scopus 로고    scopus 로고
    • Dynamics of a combined Medea-underdominant population transformation system
    • Gokhale, C. S., Reeves, R. G. & Reed, F. A. Dynamics of a combined Medea-underdominant population transformation system. BMC Evol. Biol. 14, 98 (2014).
    • (2014) BMC Evol. Biol , vol.14 , pp. 98
    • Gokhale, C.S.1    Reeves, R.G.2    Reed, F.A.3
  • 100
    • 34548221335 scopus 로고    scopus 로고
    • Introducing transgenes into insect populations using combined gene-drive strategies: Modeling and analysis
    • Huang, Y., Magori, K., Lloyd, A. L. & Gould, F. Introducing transgenes into insect populations using combined gene-drive strategies: modeling and analysis. Insect Biochem. Mol. Biol. 37, 1054-1063 (2007).
    • (2007) Insect Biochem. Mol. Biol , vol.37 , pp. 1054-1063
    • Huang, Y.1    Magori, K.2    Lloyd, A.L.3    Gould, F.4
  • 102
    • 0001344131 scopus 로고
    • Studies on Rickettsia-like micro-organisms in insects
    • Hertig, M. & Wolbach, S. B. Studies on Rickettsia-like micro-organisms in insects. J. Med. Res. 44, 329-374 (1924).
    • (1924) J. Med. Res , vol.44 , pp. 329-374
    • Hertig, M.1    Wolbach, S.B.2
  • 103
    • 72249105145 scopus 로고    scopus 로고
    • A Wolbachia symbiont in Aedes aegypti limits infection with dengue Chikungunya, and Plasmodium
    • Moreira, L. A., et al. A Wolbachia symbiont in Aedes aegypti limits infection with dengue, Chikungunya, and Plasmodium. Cell 139, 1268-1278 (2009).
    • (2009) Cell , vol.139 , pp. 1268-1278
    • Moreira, L.A.1
  • 104
    • 84877607408 scopus 로고    scopus 로고
    • Wolbachia invades Anopheles stephensi populations and induces refractoriness to Plasmodium infection
    • Bian, G., et al. Wolbachia invades Anopheles stephensi populations and induces refractoriness to Plasmodium infection. Science 340, 748-751 (2013).
    • (2013) Science , vol.340 , pp. 748-751
    • Bian, G.1
  • 105
    • 84879527154 scopus 로고    scopus 로고
    • Replacing a native Wolbachia with a novel strain results in an increase in endosymbiont load and resistance to dengue virus in a mosquito vector
    • Bian, G., Zhou, G., Lu, P. & Xi, Z. Replacing a native Wolbachia with a novel strain results in an increase in endosymbiont load and resistance to dengue virus in a mosquito vector. PLoS Negl. Trop. Dis. 7, e2250 (2013).
    • (2013) PLoS Negl. Trop. Dis , vol.7 , pp. e2250
    • Bian, G.1    Zhou, G.2    Lu, P.3    Xi, Z.4
  • 106
    • 84855987167 scopus 로고    scopus 로고
    • Wolbachia strain wMel induces cytoplasmic incompatibility and blocks dengue transmission in Aedes albopictus
    • Blagrove, M. S., Arias-Goeta, C., Failloux, A. B. & Sinkins, S. P. Wolbachia strain wMel induces cytoplasmic incompatibility and blocks dengue transmission in Aedes albopictus. Proc. Natl Acad. Sci. USA 109, 255-260 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , pp. 255-260
    • Blagrove, M.S.1    Arias-Goeta, C.2    Failloux, A.B.3    Sinkins, S.P.4
  • 107
    • 70349664283 scopus 로고    scopus 로고
    • Immune activation by life-shortening Wolbachia and reduced filarial competence in mosquitoes
    • Kambris, Z., Cook, P. E., Phuc, H. K. & Sinkins, S. P. Immune activation by life-shortening Wolbachia and reduced filarial competence in mosquitoes. Science 326, 134-136 (2009).
    • (2009) Science , vol.326 , pp. 134-136
    • Kambris, Z.1    Cook, P.E.2    Phuc, H.K.3    Sinkins, S.P.4
  • 108
    • 84885016336 scopus 로고    scopus 로고
    • Sinkins, S. P. Wolbachia and arbovirus inhibition in mosquitoes
    • Sinkins, S. P. Wolbachia and arbovirus inhibition in mosquitoes. Future Microbiol. 8, 1249-1256 (2013).
    • (2013) Future Microbiol , vol.8 , pp. 1249-1256
  • 109
    • 58149264955 scopus 로고    scopus 로고
    • Stable introduction of a life-shortening Wolbachia infection into the mosquito Aedes aegypti
    • McMeniman, C. J., et al. Stable introduction of a life-shortening Wolbachia infection into the mosquito Aedes aegypti. Science 323, 141-144 (2009).
    • (2009) Science , vol.323 , pp. 141-144
    • McMeniman, C.J.1
  • 110
    • 0038699637 scopus 로고    scopus 로고
    • Wolbachia-induced mortality as a mechanism to modulate pathogen transmission by vector arthropods
    • Rasgon, J. L., Styer, L. M. & Scott, T. W. Wolbachia-induced mortality as a mechanism to modulate pathogen transmission by vector arthropods. J. Med. Entomol. 40, 125-132 (2003).
    • (2003) J. Med. Entomol , vol.40 , pp. 125-132
    • Rasgon, J.L.1    Styer, L.M.2    Scott, T.W.3
  • 111
    • 80051510985 scopus 로고    scopus 로고
    • Successful establishment of Wolbachia in Aedes populations to suppress dengue transmission
    • Hoffmann, A. A., et al. Successful establishment of Wolbachia in Aedes populations to suppress dengue transmission. Nature 476, 454-457 (2011).
    • (2011) Nature , vol.476 , pp. 454-457
    • Hoffmann, A.A.1
  • 112
    • 80051511670 scopus 로고    scopus 로고
    • The wMel Wolbachia strain blocks dengue and invades caged Aedes aegypti populations
    • Walker, T., et al. The wMel Wolbachia strain blocks dengue and invades caged Aedes aegypti populations. Nature 476, 450-453 (2011).
    • (2011) Nature , vol.476 , pp. 450-453
    • Walker, T.1
  • 113
    • 27744526920 scopus 로고    scopus 로고
    • Transposable element insertion location bias and the dynamics of gene drive in mosquito populations
    • Rasgon, J. L. & Gould, F. Transposable element insertion location bias and the dynamics of gene drive in mosquito populations. Insect Mol. Biol. 14, 493-500 (2005).
    • (2005) Insect Mol. Biol , vol.14 , pp. 493-500
    • Rasgon, J.L.1    Gould, F.2
  • 114
    • 79251648043 scopus 로고    scopus 로고
    • Mobility properties of the HERMES transposable element in transgenic lines of Aedes aegypti
    • Smith, R. C. & Atkinson, P. W. Mobility properties of the Hermes transposable element in transgenic lines of Aedes aegypti. Genetica 139, 7-22 (2011).
    • (2011) Genetica , vol.139 , pp. 7-22
    • Smith, R.C.1    Atkinson, P.W.2
  • 117
    • 57349097202 scopus 로고    scopus 로고
    • A killer-rescue system for self-limiting gene drive of anti-pathogen constructs
    • Gould, F., Huang, Y., Legros, M. & Lloyd, A. L. A killer-rescue system for self-limiting gene drive of anti-pathogen constructs. Proc. Biol. Sci. 275, 2823-2829 (2008).
    • (2008) Proc. Biol. Sci , vol.275 , pp. 2823-2829
    • Gould, F.1    Huang, Y.2    Legros, M.3    Lloyd, A.L.4
  • 118
    • 79954545721 scopus 로고    scopus 로고
    • Inverse Medea as a novel gene drive system for local population replacement: A theoretical analysis
    • Marshall, J. M. & Hay, B. A. Inverse Medea as a novel gene drive system for local population replacement: a theoretical analysis. J. Hered. 102, 336-341 (2011).
    • (2011) J. Hered , vol.102 , pp. 336-341
    • Marshall, J.M.1    Hay, B.A.2
  • 119
    • 80054955849 scopus 로고    scopus 로고
    • The toxin and antidote puzzle: New ways to control insect pest populations through manipulating inheritance
    • Marshall, J. M. The toxin and antidote puzzle: new ways to control insect pest populations through manipulating inheritance. Bioeng. Bugs 2, 235-240 (2011).
    • (2011) Bioeng. Bugs , vol.2 , pp. 235-240
    • Marshall, J.M.1
  • 120
    • 79951547958 scopus 로고    scopus 로고
    • Semele: A killer-male, rescue-female system for suppression and replacement of insect disease vector populations
    • Marshall, J. M., Pittman, G. W., Buchman, A. B. & Hay, B. A. Semele: a killer-male, rescue-female system for suppression and replacement of insect disease vector populations. Genetics 187, 535-551 (2011).
    • (2011) Genetics , vol.187 , pp. 535-551
    • Marshall, J.M.1    Pittman, G.W.2    Buchman, A.B.3    Hay, B.A.4
  • 121
    • 84863472973 scopus 로고    scopus 로고
    • General principles of single-construct chromosomal gene drive
    • Marshall, J. M. & Hay, B. A. General principles of single-construct chromosomal gene drive. Evolution 66, 2150-2166 (2012).
    • (2012) Evolution , vol.66 , pp. 2150-2166
    • Marshall, J.M.1    Hay, B.A.2
  • 122
    • 84904622855 scopus 로고    scopus 로고
    • Medusa: A novel gene drive system for confined suppression of insect populations
    • Marshall, J. M. & Hay, B. A. Medusa: a novel gene drive system for confined suppression of insect populations. PLoS ONE 9, e102694 (2014).
    • (2014) PLoS ONE , vol.9 , pp. e102694
    • Marshall, J.M.1    Hay, B.A.2
  • 123
    • 40049086593 scopus 로고    scopus 로고
    • Transgenic mosquitoes and the fight against malaria: Managing technology push in a turbulent GMO world
    • Knols, B. G., Bossin, H. C., Mukabana, W. R. & Robinson, A. S. Transgenic mosquitoes and the fight against malaria: managing technology push in a turbulent GMO world. Am. J. Trop. Med. Hyg. 77, 232-242 (2007).
    • (2007) Am. J. Trop. Med. Hyg , vol.77 , pp. 232-242
    • Knols, B.G.1    Bossin, H.C.2    Mukabana, W.R.3    Robinson, A.S.4
  • 124
    • 84940556654 scopus 로고    scopus 로고
    • Opinion: Is CRISPR-based gene drive a biocontrol silver bullet or global conservation threat?
    • Webber, B. L., Raghu, S. & Edwards, O. R. Opinion: is CRISPR-based gene drive a biocontrol silver bullet or global conservation threat?. Proc. Natl Acad. Sci. USA 112, 10565-10567 (2015).
    • (2015) Proc. Natl Acad. Sci. USA , vol.112 , pp. 10565-10567
    • Webber, B.L.1    Raghu, S.2    Edwards, O.R.3
  • 125
    • 84907264709 scopus 로고    scopus 로고
    • Gene drives raise dual-use concerns
    • Gurwitz, D. Gene drives raise dual-use concerns. Science 345, 1010 (2014).
    • (2014) Science , vol.345 , pp. 1010
    • Gurwitz, D.1
  • 126
    • 84907260700 scopus 로고    scopus 로고
    • Gene drives raise dual-use concerns-response
    • Oye, K. A. & Esvelt, K. M. Gene drives raise dual-use concerns-response. Science 345, 1010-1011 (2014).
    • (2014) Science , vol.345 , pp. 1010-1011
    • Oye, K.A.1    Esvelt, K.M.2
  • 127
    • 77956670584 scopus 로고    scopus 로고
    • The Cartagena Protocol and genetically modified mosquitoes
    • Marshall, J. M. The Cartagena Protocol and genetically modified mosquitoes. Nat. Biotechnol. 28, 896-897 (2010).
    • (2010) Nat. Biotechnol , vol.28 , pp. 896-897
    • Marshall, J.M.1
  • 128
    • 84865972754 scopus 로고    scopus 로고
    • The importance of long-term social research in enabling participation and developing engagement strategies for new dengue control technologies
    • McNaughton, D. The importance of long-term social research in enabling participation and developing engagement strategies for new dengue control technologies. PLoS Negl. Trop. Dis. 6, e1785 (2012).
    • (2012) PLoS Negl. Trop. Dis , vol.6 , pp. e1785
    • McNaughton, D.1
  • 129
    • 84938787080 scopus 로고    scopus 로고
    • Suppression of a field population of Aedes aegypti in Brazil by sustained release of transgenic male mosquitoes
    • Carvalho, D. O., et al. Suppression of a field population of Aedes aegypti in Brazil by sustained release of transgenic male mosquitoes. PLoS Negl. Trop. Dis. 9, e0003864 (2015).
    • (2015) PLoS Negl. Trop. Dis , vol.9 , pp. e0003864
    • Carvalho, D.O.1
  • 130
    • 84864603728 scopus 로고    scopus 로고
    • Successful suppression of a field mosquito population by sustained release of engineered male mosquitoes
    • Harris, A. F., et al. Successful suppression of a field mosquito population by sustained release of engineered male mosquitoes. Nat. Biotechnol. 30, 828-830 (2012).
    • (2012) Nat. Biotechnol , vol.30 , pp. 828-830
    • Harris, A.F.1
  • 131
    • 80755189331 scopus 로고    scopus 로고
    • Field performance of engineered male mosquitoes
    • Harris, A. F., et al. Field performance of engineered male mosquitoes. Nat. Biotechnol. 29, 1034-1037 (2011).
    • (2011) Nat. Biotechnol , vol.29 , pp. 1034-1037
    • Harris, A.F.1
  • 132
    • 84865421148 scopus 로고    scopus 로고
    • Open field release of genetically engineered sterile male Aedes aegypti in Malaysia
    • Lacroix, R., et al. Open field release of genetically engineered sterile male Aedes aegypti in Malaysia. PLoS ONE 7, e42771 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e42771
    • Lacroix, R.1
  • 133
    • 80052713070 scopus 로고    scopus 로고
    • Field performance of a genetically engineered strain of pink bollworm
    • Simmons, G. S., et al. Field performance of a genetically engineered strain of pink bollworm. PLoS ONE 6, e24110 (2011).
    • (2011) PLoS ONE , vol.6 , pp. e24110
    • Simmons, G.S.1
  • 134
    • 77952033542 scopus 로고    scopus 로고
    • Perspectives of people in Mali toward genetically-modified mosquitoes for malaria control
    • Marshall, J. M., Toure, M. B., Traore, M. M., Famenini, S. & Taylor, C. E. Perspectives of people in Mali toward genetically-modified mosquitoes for malaria control. Malar. J. 9, 128 (2010).
    • (2010) Malar. J. , vol.9 , pp. 128
    • Marshall, J.M.1    Toure, M.B.2    Traore, M.M.3    Famenini, S.4    Taylor, C.E.5
  • 135
    • 12344263017 scopus 로고    scopus 로고
    • Gene drive systems in mosquitoes: Rules of the road
    • James, A. A. Gene drive systems in mosquitoes: rules of the road. Trends Parasitol. 21, 64-67 (2005).
    • (2005) Trends Parasitol , vol.21 , pp. 64-67
    • James, A.A.1
  • 136
    • 84887515382 scopus 로고    scopus 로고
    • Release of genetically engineered insects: A framework to identify potential ecological effects
    • David, A. S., Kaser, J. M., Morey, A. C., Roth, A. M. & Andow, D. A. Release of genetically engineered insects: a framework to identify potential ecological effects. Ecol. Evol. 3, 4000-4015 (2013).
    • (2013) Ecol. Evol , vol.3 , pp. 4000-4015
    • David, A.S.1    Kaser, J.M.2    Morey, A.C.3    Roth, A.M.4    Andow, D.A.5
  • 137
    • 84870728725 scopus 로고    scopus 로고
    • Considerations in the design of clinical trials to test novel entomological approaches to dengue control
    • Wolbers, M., Kleinschmidt, I., Simmons, C. P. & Donnelly, C. A. Considerations in the design of clinical trials to test novel entomological approaches to dengue control. PLoS Negl. Trop. Dis. 6, e1937 (2012).
    • (2012) PLoS Negl. Trop. Dis , vol.6 , pp. e1937
    • Wolbers, M.1    Kleinschmidt, I.2    Simmons, C.P.3    Donnelly, C.A.4
  • 138
    • 61449199821 scopus 로고    scopus 로고
    • The effect of gene drive on containment of transgenic mosquitoes
    • Marshall, J. M. The effect of gene drive on containment of transgenic mosquitoes. J. Theor. Biol. 258, 250-265 (2009).
    • (2009) J. Theor. Biol , vol.258 , pp. 250-265
    • Marshall, J.M.1
  • 139
    • 82155199410 scopus 로고    scopus 로고
    • Confinement of gene drive systems to local populations: A comparative analysis
    • Marshall, J. M. & Hay, B. A. Confinement of gene drive systems to local populations: a comparative analysis. J. Theor. Biol. 294, 153-171 (2012).
    • (2012) J. Theor. Biol , vol.294 , pp. 153-171
    • Marshall, J.M.1    Hay, B.A.2
  • 140
    • 84934443922 scopus 로고    scopus 로고
    • Mosquito transgenic technologies to reduce Plasmodium transmission
    • Fuchs, S., Nolan, T. & Crisanti, A. Mosquito transgenic technologies to reduce Plasmodium transmission. Methods Mol. Biol. 923, 601-622 (2013).
    • (2013) Methods Mol. Biol , vol.923 , pp. 601-622
    • Fuchs, S.1    Nolan, T.2    Crisanti, A.3
  • 141
    • 84875269445 scopus 로고    scopus 로고
    • Genetic approaches to interfere with malaria transmission by vector mosquitoes
    • Wang, S. & Jacobs-Lorena, M. Genetic approaches to interfere with malaria transmission by vector mosquitoes. Trends Biotechnol. 31, 185-193 (2013).
    • (2013) Trends Biotechnol , vol.31 , pp. 185-193
    • Wang, S.1    Jacobs-Lorena, M.2
  • 142
    • 77957686131 scopus 로고    scopus 로고
    • Activation of Akt signaling reduces the prevalence and intensity of malaria parasite infection and lifespan in Anopheles stephensi mosquitoes
    • Corby-Harris, V., et al. Activation of Akt signaling reduces the prevalence and intensity of malaria parasite infection and lifespan in Anopheles stephensi mosquitoes. PLoS Pathog. 6, e1001003 (2010).
    • (2010) PLoS Pathog , vol.6 , pp. e1001003
    • Corby-Harris, V.1
  • 143
    • 84872618698 scopus 로고    scopus 로고
    • Reduction of malaria transmission by transgenic mosquitoes expressing an antisporozoite antibody in their salivary glands
    • Sumitani, M., et al. Reduction of malaria transmission by transgenic mosquitoes expressing an antisporozoite antibody in their salivary glands. Insect Mol. Biol. 22, 41-51 (2013).
    • (2013) Insect Mol. Biol , vol.22 , pp. 41-51
    • Sumitani, M.1
  • 144
    • 84939975362 scopus 로고    scopus 로고
    • Disruption of dengue virus transmission by mosquitoes
    • Franz, A. W., Balaraman, V. & Fraser, M. J. Jr. Disruption of dengue virus transmission by mosquitoes. Curr. Opin. Insect Sci. 8, 88-96 (2015).
    • (2015) Curr. Opin. Insect Sci , vol.8 , pp. 88-96
    • Franz, A.W.1    Balaraman, V.2    Fraser, M.J.3
  • 145
    • 84901793586 scopus 로고    scopus 로고
    • Fitness impact and stability of a transgene conferring resistance to dengue 2 virus following introgression into a genetically diverse Aedes aegypti strain
    • Franz, A. W., et al. Fitness impact and stability of a transgene conferring resistance to dengue 2 virus following introgression into a genetically diverse Aedes aegypti strain. PLoS Negl. Trop. Dis. 8, e2833 (2014).
    • (2014) PLoS Negl. Trop. Dis , vol.8 , pp. e2833
    • Franz, A.W.1
  • 146
    • 84873814207 scopus 로고    scopus 로고
    • Biology and management of Asian citrus psyllid, vector of the huanglongbing pathogens
    • Grafton-Cardwell, E. E., Stelinski, L. L. & Stansly, P. A. Biology and management of Asian citrus psyllid, vector of the huanglongbing pathogens. Annu. Rev. Entomol. 58, 413-432 (2013).
    • (2013) Annu. Rev. Entomol , vol.58 , pp. 413-432
    • Grafton-Cardwell, E.E.1    Stelinski, L.L.2    Stansly, P.A.3
  • 147
    • 84878680711 scopus 로고    scopus 로고
    • Complex history of the amphibian-killing chytrid fungus revealed with genome resequencing data
    • Rosenblum, E. B., et al. Complex history of the amphibian-killing chytrid fungus revealed with genome resequencing data. Proc. Natl Acad. Sci. USA 110, 9385-9390 (2013).
    • (2013) Proc. Natl Acad. Sci. USA , vol.110 , pp. 9385-9390
    • Rosenblum, E.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.