A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae

Nature Biotechnology

Volumn 34, Issue 1, 2016, Pages 78-83

  Hammond, Andrew ^a   Galizi, Roberto ^a   Kyrou, Kyros ^a   Simoni, Alekos ^a   Siniscalchi, Carla ^b   Katsanos, Dimitris ^a   Gribble, Matthew ^a   Baker, Dean ^c   Marois, Eric ^d   Russell, Steven ^c   Burt, Austin ^a   Windbichler, Nikolai ^a   Crisanti, Andrea ^a   Nolan, Tony ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF PERUGIA   (Italy)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES;

INSECT POPULATION; MALARIA MOSQUITOES; MALARIA TRANSMISSION; MINIMUM REQUIREMENTS; MOLECULAR LEVELS; MOSQUITO POPULATIONS; POPULATION MODEL; TRANSMISSION RATES;

GENES;

ENDONUCLEASE;

ALLELE; ANOPHELES GAMBIAE; ARTICLE; CRISPR CAS SYSTEM; CRISPR CAS9 SYSTEM; FEMALE; FEMALE STERILITY; GENE DISRUPTION; MALARIA; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROGENY; RECESSIVE INHERITANCE; REPRODUCTION; ANIMAL; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; GENETICS; INSECT VECTOR; PHYSIOLOGY; TRANSMISSION;

ANIMALS; ANOPHELES GAMBIAE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; FEMALE; INSECT VECTORS; MALARIA;

EID: 84953730637     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.3439     Document Type: Article

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