Considerations in the Design of Clinical Trials to Test Novel Entomological Approaches to Dengue Control

PLoS Neglected Tropical Diseases

Volumn 6, Issue 11, 2012, Pages

  Wolbers, Marcel ^a,b   Kleinschmidt, Immo ^c   Simmons, Cameron P ^a,b   Donnelly, Christl A ^d  

^a OXFORD UNIVERSITY CLINICAL RESEARCH UNIT   (Viet Nam)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AEDES AEGYPTI; ARTICLE; CLINICAL RESEARCH; DENGUE; DENGUE VIRUS; DISEASE CONTROL; DRUG EFFICACY; HUMAN; NONHUMAN; RANDOMIZED CONTROLLED TRIAL (TOPIC); SAMPLE SIZE; VECTOR CONTROL; WOLBACHIA;

EID: 84870728725     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0001937     Document Type: Article

References (16)

1. Suaya JA, Shepard DS, Siqueira JB, Martelli CT, Lum LC, et al. (2009) Cost of Dengue cases in eight countries in the Americas and Asia: a prospective study. Am J Trop Med Hyg 80: 846-855.
2. Simmons CP, Farrar JJ, Nguyen vV, Wills B, (2012) Dengue. New Engl J Med 366: 1423-1432.
3. Balmaseda A, Standish K, Mercado JC, Matute JC, Tellez Y, et al. (2010) Trends in patterns of dengue transmission over 4 years in a pediatric cohort study in Nicaragua. J Infect Dis 201: 5-14.
4. Wise de Valdez MR, Nimmo D, Betz J, Gong HF, James AA, et al. (2011) Genetic elimination of dengue vector mosquitoes. Proc Natl Acad Sci U S A 108: 4772-4775.
5. McMeniman CJ, Lane RV, Cass BN, Fong AW, Sidhu M, et al. (2009) Stable introduction of a life-shortening Wolbachia infection into the mosquito Aedes aegypti. Science 323: 141-144.
6. Walker T, Johnson PH, Moreira LA, Iturbe-Ormaetxe I, Frentiu FD, et al. (2011) The wMel Wolbachia strain blocks dengue and invades caged Aedes aegypti populations. Nature 476: 450-453.
7. Hoffmann AA, Montgomery BL, Popovici J, Iturbe-Ormaetxe I, Johnson PH, et al. (2011) Successful establishment of Wolbachia in Aedes populations to suppress dengue transmission. Nature 476: 454-457.
8. James S, Simmons CP, James AA, (2011) Ecology. Mosquito trials. Science 334: 771-772.
9. Vong S, Khieu V, Glass O, Ly S, Duong V, et al. (2010) Dengue incidence in urban and rural Cambodia: results from population-based active fever surveillance, 2006-2008. PLoS Negl Trop Dis 4: e903 doi:10.1371/journal.pntd.0000903.
10. Endy TP, Chunsuttiwat S, Nisalak A, Libraty DH, Green S, et al. (2002) Epidemiology of inapparent and symptomatic acute dengue virus infection: a prospective study of primary school children in Kamphaeng Phet, Thailand. Am J Epidemiol 156: 40-51.
11. Liebman KA, Stoddard ST, Morrison AC, Rocha C, Minnick S, et al. (2012) Spatial dimensions of dengue virus transmission across interepidemic and epidemic periods in Iquitos, Peru (1999-2003). PLoS Negl Trop Dis 6: e1472 doi:10.1371/journal.pntd.0001472.
12. Lenhart A, Orelus N, Maskill R, Alexander N, Streit T, et al. (2008) Insecticide-treated bednets to control dengue vectors: preliminary evidence from a controlled trial in Haiti. Trop Med Int Health 13: 56-67.
13. Marcombe S, Darriet F, Agnew P, Etienne M, Yp-Tcha MM, et al. (2011) Field efficacy of new larvicide products for control of multi-resistant Aedes aegypti populations in Martinique (French West Indies). Am J Trop Med Hyg 84: 118-126.
14. Richard J Hayes and Lawrence H Moulton (2009) Cluster randomised trials. Boca Raton (FL): CRC Press.
15. Hussey MA, Hughes JP, (2007) Design and analysis of stepped wedge cluster randomized trials. Contemp Clinical Trials 28: 182-191.
16. Mdege ND, Man MS, Taylor Nee Brown CA, Torgerson DJ, (2011) Systematic review of stepped wedge cluster randomized trials shows that design is particularly used to evaluate interventions during routine implementation. J Clin Epidemiol 64: 936-948.