NOX3-Targeted therapies for inner ear pathologies

Current Pharmaceutical Design

Volumn 21, Issue 41, 2015, Pages 5977-5987

  Rousset, Francis ^a   Carnesecchi, Stephanie ^b   Senn, Pascal ^c   Krause, Karl Heinz ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b GENKYOTEX SA   (Switzerland)

^c Inselspital   (Switzerland)

Author keywords

Cochlea; Hearing loss; Molecular biology based inhibitors; NADPH oxidase; NOX3; Oxidative stress; Small molecules inhibitors; Vestibular system

Indexed keywords

ACETYLCYSTEINE; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; GINKGO BILOBA EXTRACT; OXIDOREDUCTASE INHIBITOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 3; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE INHIBITOR; RETINOL; THIOCTIC ACID; UNCLASSIFIED DRUG; MEMBRANE PROTEIN; MOLECULAR LIBRARY; NOX3 PROTEIN, HUMAN; NOX3 PROTEIN, MOUSE; REACTIVE OXYGEN METABOLITE;

AGE INDUCED HEARING LOSS; ARTICLE; COCHLEA; DRUG INDUCED DISEASE; HEARING IMPAIRMENT; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INNER EAR; INNER EAR DISEASE; MENIERE DISEASE; MOLECULARLY TARGETED THERAPY; NOISE INDUCED HEARING LOSS; NONHUMAN; OXIDATIVE STRESS; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PHYSIOLOGY; PRESBYACUSIS; PRIORITY JOURNAL; SUPPLEMENTATION; VESTIBULAR FUNCTION; VESTIBULAR SYSTEM; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; GENETICS; LABYRINTH DISEASES; METABOLISM; MOLECULAR LIBRARY; PATHOLOGY; PHARMACOLOGY; SYNTHESIS;

ANIMALS; HUMANS; LABYRINTH DISEASES; MEMBRANE PROTEINS; NADPH OXIDASE; REACTIVE OXYGEN SPECIES; SMALL MOLECULE LIBRARIES;

EID: 84957594056     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/1381612821666151029112421     Document Type: Article

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