A long-term high-fat diet increases oxidative stress, mitochondrial damage and apoptosis in the inner ear of d-galactose-induced aging rats

Hearing Research

Volumn 287, Issue 1-2, 2012, Pages 15-24

  Du, Zhengde ^a   Yang, Yang ^a   Hu, Yujuan ^a   Sun, Yu ^a   Zhang, Sulin ^a   Peng, Wei ^a   Zhong, Yi ^a   Huang, Xiang ^a   Kong, Weijia ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; GALACTOSE; MESSENGER RNA; MITOCHONDRIAL DNA; P22 PHOX PROTEIN; PROTEIN P22; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN; UNCOUPLING PROTEIN 2; UNCOUPLING PROTEIN 3;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL COUNT; CELL ULTRASTRUCTURE; COCHLEA; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME BINDING; EVOKED BRAIN STEM AUDITORY RESPONSE; GENE DELETION; HEARING LOSS; INNER EAR; LIPID DIET; MALE; METABOLISM; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

AGE FACTORS; AGING; ANIMALS; APOPTOSIS; AUDITORY THRESHOLD; CASPASE 3; CHRONIC DISEASE; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; DNA, MITOCHONDRIAL; DYSLIPIDEMIAS; EAR, INNER; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; GALACTOSE; IN SITU NICK-END LABELING; ION CHANNELS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NADPH OXIDASE; OXIDATIVE STRESS; PRESBYCUSIS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SEQUENCE DELETION; TIME FACTORS;

EID: 84861190708     PISSN: 03785955     EISSN: 18785891     Source Type: Journal    
DOI: 10.1016/j.heares.2012.04.012     Document Type: Article

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