A combination of cilostazol and Ginkgo biloba extract protects against cisplatin-induced Cochleo-vestibular dysfunction by inhibiting the mitochondrial apoptotic and ERK pathways

Cell Death and Disease

Volumn 4, Issue 2, 2013, Pages

  Tian, C J ^a   Kim, Y J ^a   Kim, S W ^a   Lim, H J ^a   Kim, Y S ^a   Choung, Y H ^a  

^a Ajou University School of Medicine   (South Korea)

Author keywords

Cilostazol; Cisplatin; Dizziness; Ginkgo biloba; Hearing loss

Indexed keywords

CASPASE 3; CILOSTAZOL; CISPLATIN; CYTOCHROME C; GINKGO BILOBA EXTRACT; MITOGEN ACTIVATED PROTEIN KINASE; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROTEIN BAX; PROTEIN BCL XL; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUDITORY CORTEX; AUDITORY THRESHOLD; CELL DAMAGE; CORTI ORGAN; DOSE RESPONSE; DRUG EFFECT; HAIR CELL; MALE; MITOCHONDRION; NONHUMAN; OTOLITH; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STATISTICAL SIGNIFICANCE; VESTIBULAR DISORDER;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BEHAVIOR, ANIMAL; CELL LINE; CISPLATIN; DRUG SYNERGISM; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GINKGO BILOBA; HAIR CELLS, AUDITORY; HEARING LOSS; MALE; MAP KINASE SIGNALING SYSTEM; MITOCHONDRIA; NEUROPROTECTIVE AGENTS; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; TETRAZOLES;

GINKGO BILOBA; RATTUS;

EID: 84875978907     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.33     Document Type: Article

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