Dosing study on the effectiveness of salicylate/N-acetylcysteine for prevention of noise-induced hearing loss

Noise and Health

Volumn 12, Issue 48, 2010, Pages 159-165

  Coleman, John ^a   Huang, Xinyan ^b   Liu, Jianzhong ^a   Kopke, Richard ^c   Jackson, Ronald ^a  

^a NAVAL MEDICAL CENTER SAN DIEGO   (United States)

^b Springfield Clinic   (United States)

^c HOUGH EAR INSTITUTE   (United States)

Author keywords

Anti inflammation; antioxidant; chinchilla; dose response; hair cell; hearing threshold

Indexed keywords

ACETYLCYSTEINE; NONSTEROID ANTIINFLAMMATORY AGENT; SALICYLATE SODIUM; SCAVENGER;

ANALYSIS OF VARIANCE; ANIMAL; ARTICLE; AUDITORY THRESHOLD; CHINCHILLA; COMPARATIVE STUDY; DISEASE MODEL; DRUG ADMINISTRATION; DRUG COMBINATION; DRUG EFFECT; DRUG SCREENING; EVOKED BRAIN STEM AUDITORY RESPONSE; FEMALE; HAIR CELL; HEARING TEST; INTRAPERITONEAL DRUG ADMINISTRATION; NOISE INJURY; PATHOLOGY; RANDOMIZATION; SOUND DETECTION;

ACETYLCYSTEINE; ANALYSIS OF VARIANCE; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; AUDITORY THRESHOLD; CHINCHILLA; DISEASE MODELS, ANIMAL; DRUG ADMINISTRATION SCHEDULE; DRUG COMBINATIONS; DRUG EVALUATION, PRECLINICAL; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; FEMALE; FREE RADICAL SCAVENGERS; HAIR CELLS, AUDITORY, OUTER; HEARING LOSS, NOISE-INDUCED; HEARING TESTS; INJECTIONS, INTRAPERITONEAL; RANDOM ALLOCATION; SODIUM SALICYLATE; SOUND SPECTROGRAPHY;

EID: 77954615089     PISSN: 14631741     EISSN: 19984030     Source Type: Journal    
DOI: 10.4103/1463-1741.64972     Document Type: Article

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