Autophagy in motor neuron disease: Key pathogenetic mechanisms and therapeutic targets

Molecular and Cellular Neuroscience

Volumn 72, Issue , 2016, Pages 84-90

  Cipolat Mis, Maria Sara ^a   Brajkovic, Simona ^a   Frattini, Emanuele ^a   Di Fonzo, Alessio ^a   Corti, Stefania ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

Amyotrophic lateral sclerosis; Authophagy; Protein aggregation

Indexed keywords

ADENYLATE KINASE; ALSIN; ARIMOCLOMOL; BECLIN 1; CARBAMAZEPINE; COPPER ZINC SUPEROXIDE DISMUTASE; CURCUMIN; DYNACTIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; LITHIUM; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; OPTINEURIN; PLACEBO; RAPAMYCIN; RESVERATROL; RNA BINDING PROTEIN; TAR DNA BINDING PROTEIN; TREHALOSE; UNCLASSIFIED DRUG; VALOSIN CONTAINING PROTEIN; VALPROIC ACID; PROTEIN KINASE INHIBITOR; TARGET OF RAPAMYCIN KINASE;

AMYOTROPHIC LATERAL SCLEROSIS; ANTIINFLAMMATORY ACTIVITY; AUTOPHAGOSOME; AUTOPHAGY; CELL SURVIVAL; DRUG TARGETING; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; FUS GENE; GENE; GENE MUTATION; HUMAN; LYSOSOME; MACROAUTOPHAGY; MEDICAL RESEARCH; MOTOR NEURON DISEASE; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SOD1 GENE; TARDBP GENE; UNFOLDED PROTEIN RESPONSE; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG DEVELOPMENT; METABOLISM; MOLECULARLY TARGETED THERAPY;

ANIMALS; AUTOPHAGY; DRUG DISCOVERY; HUMANS; MOLECULAR TARGETED THERAPY; MOTOR NEURON DISEASE; PROTEIN KINASE INHIBITORS; TOR SERINE-THREONINE KINASES;

EID: 84957045630     PISSN: 10447431     EISSN: 10959327     Source Type: Journal    
DOI: 10.1016/j.mcn.2016.01.012     Document Type: Review

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