Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models

Nature Chemical Biology

Volumn 10, Issue 8, 2014, Pages 677-685

  Barmada, Sami J ^a,b,c   Serio, Andrea ^d,e,f   Arjun, Arpana ^a   Bilican, Bilada ^d,e   Daub, Aaron ^a   Ando, D Michael ^a,g   Tsvetkov, Andrey ^a,h   Pleiss, Michael ⁱ   Li, Xingli ^c   Peisach, Daniel ^c   Shaw, Christopher ^j   Chandran, Siddharthan ^a,e   Finkbeiner, Steven ^{a,b,g,i,k,l,m}  

^a GLADSTONE INSTITUTE OF NEUROLOGICAL DISEASE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

^e UNIVERSITY OF EDINBURGH   (United Kingdom)

^f IMPERIAL COLLEGE LONDON   (United Kingdom)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

ⁱ GLADSTONE INSTITUTES   (United States)

^j KING'S COLLEGE LONDON   (United Kingdom)

^k Taube Koret Center for Huntington's Disease Research   (United States)

^l Hellman Family Foundation Program in Alzheimer's Disease Research   (United States)

^m Roddenberry Stem Cell Program   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

TAR DNA BINDING PROTEIN;

ADULT; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ARTICLE; ASTROCYTE; AUTOPHAGOSOME; AUTOPHAGY; BRAIN CELL; CASE REPORT; CELL DEATH; CELL SURVIVAL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO; FEMALE; FIBROBLAST; FLUORESCENCE MICROSCOPY; GENE MUTATION; HALF LIFE TIME; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MALE; MIDDLE AGED; MOTONEURON; NERVE CELL; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; PHARMACOPHORE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN LOCALIZATION; PROTEIN METABOLISM; RAT; SINGLE CELL ANALYSIS; SINGLE CELL OPTICAL METHOD; WILD TYPE;

MURINAE;

AMINO ACID SEQUENCE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ASTROCYTES; AUTOPHAGY; CELL SURVIVAL; CELLS, CULTURED; DNA-BINDING PROTEINS; FLUPHENAZINE; HALF-LIFE; HUMANS; INDUCED PLURIPOTENT STEM CELLS; METHOTRIMEPRAZINE; MICE; MICROTUBULE-ASSOCIATED PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; NEURONS; RATS; REPRODUCIBILITY OF RESULTS; SINGLE-CELL ANALYSIS; SMALL MOLECULE LIBRARIES; STEM CELLS;

EID: 84904729990     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.1563     Document Type: Article

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