Mutant SOD1 in neuronal mitochondria causes toxicity and mitochondrial dynamics abnormalities

Human Molecular Genetics

Volumn 18, Issue 23, 2009, Pages 4552-4564

  Magrané, Jordi ^a   Hervias, Isabel ^a,b   Henning, Matthew S ^a,c   Damiano, Maria ^c   Kawamata, Hibiki ^a   Manfredi, Giovanni ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF NAVARRA   (Spain)

^c INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ARTICLE; CELL LINE; CELL ORGANELLE; CELL STRUCTURE; CONTROLLED STUDY; CYTOSOL; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; GENE EXPRESSION; GENE MUTATION; MITOCHONDRION; MOTONEURON; MOTOR NEURON DISEASE; MOUSE; NERVE CELL; NEURITE; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; WILD TYPE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; CELL LINE; DISEASE MODELS, ANIMAL; HUMANS; MICE; MICE, TRANSGENIC; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; MOTOR NEURONS; MUTATION; OXIDATIVE STRESS; PROTEIN TRANSPORT; SUPEROXIDE DISMUTASE;

MUS MUSCULUS;

EID: 70449417623     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddp421     Document Type: Article

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