Curcumin ameliorates the neurodegenerative pathology in A53T α-synuclein cell model of Parkinson's disease through the downregulation of mTOR/p70S6K signaling and the recovery of macroautophagy

Journal of Neuroimmune Pharmacology

Volumn 8, Issue 1, 2013, Pages 356-369

  Jiang, Tian Fang ^a   Zhang, Ying Jie ^a   Zhou, Hai Yan ^a   Wang, Hong Mei ^a   Tian, Li Peng ^a   Liu, Jun ^a   Ding, Jian Qing ^a   Chen, Sheng Di ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

synuclein; Autophagy; Curcumin; mTOR p70S6K signaling; Parkinson's disease

Indexed keywords

ALPHA SYNUCLEIN; CURCUMIN; MAMMALIAN TARGET OF RAPAMYCIN; S6 KINASE;

ARTICLE; AUTOPHAGOSOME; CONTROLLED STUDY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; INTRACELLULAR SIGNALING; MACROAUTOPHAGY; NEUROPROTECTION; PARKINSON DISEASE; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION;

ADENINE; ALPHA-SYNUCLEIN; AUTOPHAGY; BLOTTING, WESTERN; CELL LINE; CELL SURVIVAL; CURCUMIN; GENETIC VECTORS; HUMANS; IMMUNOHISTOCHEMISTRY; MACROPHAGES; NEURODEGENERATIVE DISEASES; NEUROPROTECTIVE AGENTS; PARKINSON DISEASE; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; TOR SERINE-THREONINE KINASES; TRANSFECTION;

EID: 84874645362     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-012-9431-7     Document Type: Article

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