Genetic causes of amyotrophic lateral sclerosis: New genetic analysis methodologies entailing new opportunities and challenges

Brain Research

Volumn 1607, Issue , 2015, Pages 75-93

  Marangi, Giuseppe ^a,b   Traynor, Bryan J ^a,c  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b CATHOLIC UNIVERSITY   (Italy)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Amyotrophiclateralsclerosis; Gene discovery; Genetic heterogeneity; GWAS; NGS; Somatic mosaicism

Indexed keywords

FUSED IN SARCOMA PROTEIN; RNA BINDING PROTEIN; TAR DNA BINDING PROTEIN;

AMYOTROPHIC LATERAL SCLEROSIS; CAG REPEAT; COPY NUMBER VARIATION; DNA METHYLATION; EPIGENETICS; GENE DELETION; GENE IDENTIFICATION; GENE LOCUS; GENE MUTATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; LINKAGE ANALYSIS; METHODOLOGY; MISSENSE MUTATION; MOLECULAR CLONING; MULTIFACTORIAL INHERITANCE; MUTATIONAL ANALYSIS; NEUROPATHOLOGY; NEXT GENERATION SEQUENCING; NONHUMAN; PATHOGENICITY; PHENOTYPE; PRIORITY JOURNAL; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; SOMATIC MUTATION; GENETIC PREDISPOSITION; GENETIC PROCEDURES; GENETICS; MUTATION;

AMYOTROPHIC LATERAL SCLEROSIS; GENETIC PREDISPOSITION TO DISEASE; GENETIC TECHNIQUES; HUMANS; MUTATION;

EID: 84926136044     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2014.10.009     Document Type: Review

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