Context-specific flow through the MEK/ERK module produces cell- and ligand-specific patterns of ERK single and double phosphorylation

Science Signaling

Volumn 9, Issue 413, 2016, Pages

  Iwamoto, Nao ^a   D'Alessandro, Lorenza A ^a   Depner, Sofia ^a   Hahn, Bettina ^a   Kramer, Bernhard A ^a   Lucarelli, Philippe ^a   Vlasov, Artyom ^a   Stepath, Markus ^a   Böhm, Martin E ^a   Deharde, Daniela ^b   Damm, Georg ^b   Seehofer, Daniel ^b   Lehmann, Wolf D ^a   Klingmüller, Ursula ^a,c   Schilling, Marcel ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c German Center for Lung Research   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DUAL SPECIFICITY PHOSPHATASE 6; INTERLEUKIN 6; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PAXILLIN; SCATTER FACTOR; THREONINE; TYROSINE; DUSP6 PROTEIN, HUMAN; MAPK1 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; DEPHOSPHORYLATION; DYNAMICS; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEEDBACK SYSTEM; HUMAN; HUMAN CELL; HUMAN TISSUE; KERATINOCYTE; LIVER CELL; LIVER TUMOR; MALE; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; BIOLOGICAL MODEL; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; TRANSFORMED CELL LINE;

CELL LINE, TRANSFORMED; DUAL SPECIFICITY PHOSPHATASE 6; HUMANS; MAP KINASE KINASE KINASES; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MODELS, BIOLOGICAL; PHOSPHORYLATION;

EID: 84956946896     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.aab1967     Document Type: Article

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