Biphasic responses in multi-site phosphorylation systems

Journal of the Royal Society Interface

Volumn 10, Issue 89, 2013, Pages

  Suwanmajo, Thapanar ^a   Krishnan, J ^a,b  

^a Centre for Process Systems Engineering   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Enzyme sequestration; Multi site modification; Non monotonic response; Shared enzyme; Signal processing; Substrate sequestration

Indexed keywords

ENZYMES; SIGNAL PROCESSING;

BIPHASIC RESPONSE; COMPETING EFFECTS; DIFFERENT MECHANISMS; MODIFICATION MECHANISM; MOLECULAR SIGNALS; MULTI-SITE; NON-MONOTONIC RESPONSE; PHOSPHORYLATED SUBSTRATES;

PHOSPHORYLATION;

PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE CDC14; PHOSPHOTRANSFERASE;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DEPHOSPHORYLATION; ENZYME BINDING; ENZYME KINETICS; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; MULTI SITE PHOSPHORYLATION; SIGNAL TRANSDUCTION; SIMULATION; STEADY STATE; ALGORITHM; CHEMICAL STRUCTURE; COMPUTER SIMULATION; ENZYME SEQUESTRATION; METABOLISM; MULTI-SITE MODIFICATION; NON-MONOTONIC RESPONSE; PHOSPHORYLATION; PHYSIOLOGY; SHARED ENZYME; SIGNAL PROCESSING; SUBSTRATE SEQUESTRATION;

ENZYME SEQUESTRATION; MULTI-SITE MODIFICATION; NON-MONOTONIC RESPONSE; SHARED ENZYME; SIGNAL PROCESSING; SUBSTRATE SEQUESTRATION;

ALGORITHMS; COMPUTER SIMULATION; MODELS, MOLECULAR; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHORYLATION; PHOSPHOTRANSFERASES;

EID: 84899771032     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2013.0742     Document Type: Article

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