Phosphatase and tensin homologue phosphorylation in the C-terminal regulatory domain is frequently observed in acute myeloid leukaemia and associated with poor clinical outcome

British Journal of Haematology

Volumn 122, Issue 3, 2003, Pages 454-456

  Cheong, June Won ^a   Eom, Ju In ^b   Maeng, Ho Young ^a   Lee, Seung Tae ^a   Hahn, Jee Sook ^a   Ko, Yun Woong ^a   Min, Yoo Hong ^a  

^a Yonsei University College of Medicine   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Akt; AML; Constitutive phosphorylation; Prognosis; PTEN

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; ARTICLE; CANCER REGRESSION; CARBOXY TERMINAL SEQUENCE; FEMALE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; SEQUENCE HOMOLOGY;

ACUTE DISEASE; ADOLESCENT; ADULT; AGED; BLOTTING, WESTERN; DNA-BINDING PROTEINS; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GLYCOGEN SYNTHASE KINASE 3; HUMANS; LEUKEMIA, MYELOID; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHORYLATION; PROGNOSIS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; STATISTICS, NONPARAMETRIC; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS;

EID: 0043130432     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2003.04452.x     Document Type: Article

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