-
1
-
-
77749270677
-
Ultrahigh-throughput screening in drop-based microfluidics for directed evolution
-
Agresti JJ, Antipov E, Abate AR, Ahn K, Rowat AC, Baret J-C, Marquez M, Klibanov AM, Griffiths AD, Weitz DA. 2010. Ultrahigh-throughput screening in drop-based microfluidics for directed evolution. Proceedings of the National Academy of Sciences of the United States of America 107:4004-4009. doi: 10.1073/pnas.0910781107.
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, pp. 4004-4009
-
-
Agresti, J.J.1
Antipov, E.2
Abate, A.R.3
Ahn, K.4
Rowat, A.C.5
Baret, J.-C.6
Marquez, M.7
Klibanov, A.M.8
Griffiths, A.D.9
Weitz, D.A.10
-
2
-
-
22844452835
-
Construction of lycopene-overproducing e. Coli strains by combining systematic and combinatorial gene knockout targets
-
Alper H, Miyaoku K, Stephanopoulos G. 2005. Construction of lycopene-overproducing e. coli strains by combining systematic and combinatorial gene knockout targets. Nature Biotechnology 23:612-616. doi: 10.1038/nbt1083.
-
(2005)
Nature Biotechnology
, vol.23
, pp. 612-616
-
-
Alper, H.1
Miyaoku, K.2
Stephanopoulos, G.3
-
3
-
-
33748195107
-
A rapid, reversible, and tunable method to regulate protein function in living cells using synthetic small molecules
-
Banaszynski LA, Chen Ling-chun, Maynard-Smith LA, Ooi AGL, Wandless TJ. 2006. A rapid, reversible, and tunable method to regulate protein function in living cells using synthetic small molecules. Cell 126:995-1004.doi: 10.1016/j.cell.2006.07.025.
-
(2006)
Cell
, vol.126
, pp. 995-1004
-
-
Banaszynski, L.A.1
Ling-Chun, C.2
Maynard-Smith, L.A.3
Ooi, A.4
Wandless, T.J.5
-
4
-
-
53549129978
-
Chemical control of protein stability and function in living mice
-
Banaszynski LA, Sellmyer MA, Contag CH, Wandless TJ, Thorne SH. 2008. Chemical control of protein stability and function in living mice. Nature Medicine 14:1123-1127. doi: 10.1038/nm.1754.
-
(2008)
Nature Medicine
, vol.14
, pp. 1123-1127
-
-
Banaszynski, L.A.1
Sellmyer, M.A.2
Contag, C.H.3
Wandless, T.J.4
Thorne, S.H.5
-
6
-
-
77954656041
-
An improved yeast transformation method for the generation of very large human antibody libraries
-
Benatuil L, Perez JM, Belk J, Hsieh C-M. 2010. An improved yeast transformation method for the generation of very large human antibody libraries. Protein Engineering Design and Selection 23:155-159. doi: 10.1093/protein/gzq002.
-
(2010)
Protein Engineering Design and Selection
, vol.23
, pp. 155-159
-
-
Benatuil, L.1
Perez, J.M.2
Belk, J.3
Hsieh, C.-M.4
-
7
-
-
84891710947
-
Analysis of off-target effects of CRISPR/Cas- derived RNA-guided endonucleases and nickases
-
Cho SW, Kim S, Kim Y, Kweon J, Kim HS, Bae S, Kim J-S. 2014. Analysis of off-target effects of CRISPR/Cas- derived RNA-guided endonucleases and nickases. Genome Research 24:132-141. doi: 10.1101/gr.162339.113.
-
(2014)
Genome Research
, vol.24
, pp. 132-141
-
-
Cho, S.W.1
Kim, S.2
Kim, Y.3
Kweon, J.4
Kim, H.S.5
Bae, S.6
Kim, J.-S.7
-
8
-
-
84886022252
-
Programming adaptive control to evolve increased metabolite production
-
Chou HH, Keasling JD. 2013. Programming adaptive control to evolve increased metabolite production. Nature Communications 4. doi: 10.1038/ncomms3595.
-
(2013)
Nature Communications
, pp. 4
-
-
Chou, H.H.1
Keasling, J.D.2
-
9
-
-
0032447801
-
Floral dip: A simplified method forAgrobacterium-mediated transformation ofArabidopsis thaliana
-
Clough SJ, Bent AF. 1998. Floral dip: a simplified method forAgrobacterium-mediated transformation ofArabidopsis thaliana. The Plant Journal 16:735-743. doi: 10.1046/j.1365-313x.1998.00343.x.
-
(1998)
The Plant Journal
, vol.16
, pp. 735-743
-
-
Clough, S.J.1
Bent, A.F.2
-
10
-
-
84876575031
-
Genome engineering in saccharomyces cerevisiae using CRISPR-cas systems
-
DiCarlo JE, Norville JE, Mali P, Rios X, Aach J, Church GM. 2013. Genome engineering in saccharomyces cerevisiae using CRISPR-cas systems. Nucleic Acids Research 41:4336-4343. doi: 10.1093/nar/gkt135.
-
(2013)
Nucleic Acids Research
, vol.41
, pp. 4336-4343
-
-
Dicarlo, J.E.1
Norville, J.E.2
Mali, P.3
Rios, X.4
Aach, J.5
Church, G.M.6
-
11
-
-
77953642931
-
High-throughput metabolic engineering: Advances in small-molecule screening and selection
-
Dietrich JA, McKee AE, Keasling JD. 2010. High-throughput metabolic engineering: advances in small-molecule screening and selection. Annual Review of Biochemistry 79:563-590. doi: 10.1146/annurev-biochem-062608-095938.
-
(2010)
Annual Review of Biochemistry
, vol.79
, pp. 563-590
-
-
Dietrich, J.A.1
McKee, A.E.2
Keasling, J.D.3
-
12
-
-
84875515904
-
Transcription factor-based screens and synthetic selections for microbial small-molecule biosynthesis
-
Dietrich JA, Shis DL, Alikhani A, Keasling JD. 2013. Transcription factor-based screens and synthetic selections for microbial small-molecule biosynthesis. ACS Synthetic Biology 2:47-58. doi: 10.1021/sb300091d.
-
(2013)
ACS Synthetic Biology
, vol.2
, pp. 47-58
-
-
Dietrich, J.A.1
Shis, D.L.2
Alikhani, A.3
Keasling, J.D.4
-
13
-
-
84926652112
-
Inducible in vivo genome editing with CRISPR-Cas9
-
Dow LE, Fisher J, O’Rourke KP, Muley A, Kastenhuber ER, Livshits G, Tschaharganeh DF, Socci ND, Lowe SW. 2015. Inducible in vivo genome editing with CRISPR-Cas9. Nature Biotechnology 33:390-394. doi: 10.1038/nbt.3155.
-
(2015)
Nature Biotechnology
, vol.33
, pp. 390-394
-
-
Dow, L.E.1
Fisher, J.2
O’Rourke, K.P.3
Muley, A.4
Kastenhuber, E.R.5
Livshits, G.6
Tschaharganeh, D.F.7
Socci, N.D.8
Lowe, S.W.9
-
14
-
-
0031936276
-
Self-sufficient biosynthesis of pregnenolone and progesterone in engineered yeast
-
Duport C, Spagnoli R, Degryse E, Pompon D. 1998. Self-sufficient biosynthesis of pregnenolone and progesterone in engineered yeast. Nature Biotechnology 16:186-189. doi: 10.1038/nbt0298-186.
-
(1998)
Nature Biotechnology
, vol.16
, pp. 186-189
-
-
Duport, C.1
Spagnoli, R.2
Degryse, E.3
Pompon, D.4
-
15
-
-
80052403213
-
Ligand-switchable substrates for a ubiquitin- proteasome system
-
Egeler EL, Urner LM, Rakhit R, Liu CW, Wandless TJ. 2011. Ligand-switchable substrates for a ubiquitin- proteasome system. Journal of Biological Chemistry 286:31328-31336. doi: 10.1074/jbc.M111.264101.
-
(2011)
Journal of Biological Chemistry
, vol.286
, pp. 31328-31336
-
-
Egeler, E.L.1
Urner, L.M.2
Rakhit, R.3
Liu, C.W.4
Wandless, T.J.5
-
16
-
-
56649114274
-
A one pot, one step, precision cloning method with high throughput capability
-
Engler C, Kandzia R, Marillonnet S, El-Shemy HA. 2008. A one pot, one step, precision cloning method with high throughput capability. PLoS ONE 3:e3647. doi: 10.1371/journal.pone.0003647.
-
(2008)
Plos ONE
, vol.3
-
-
Engler, C.1
Kandzia, R.2
Marillonnet, S.3
El-Shemy, H.A.4
-
17
-
-
30144440366
-
Yeast ATP-binding cassette transporters: Cellular cleaning pumps
-
Ernst R, Klemm R, Schmitt L, Kuchler K. 2005. Yeast ATP-binding cassette transporters: cellular cleaning pumps. Methods Enzymol 400:460-484. doi: 10.1016/S0076-6879(05)00026-1.
-
(2005)
Methods Enzymol
, vol.400
, pp. 460-484
-
-
Ernst, R.1
Klemm, R.2
Schmitt, L.3
Kuchler, K.4
-
18
-
-
84880570576
-
High-frequency off-target mutagenesis induced by CRISPR-cas nucleases in human cells
-
Fu Y, Foden JA, Khayter C, Maeder ML, Reyon D, Joung JK, Sander JD. 2013. High-frequency off-target mutagenesis induced by CRISPR-cas nucleases in human cells. Nature Biotechnology 31:822-826. doi: 10.1038/nbt.2623.
-
(2013)
Nature Biotechnology
, vol.31
, pp. 822-826
-
-
Fu, Y.1
Foden, J.A.2
Khayter, C.3
Maeder, M.L.4
Reyon, D.5
Joung, J.K.6
Sander, J.D.7
-
19
-
-
84896929630
-
Improving CRISPR-cas nuclease specificity using truncated guide RNAs
-
Fu Y, Sander JD, Reyon D, Cascio VM, Joung JK. 2014. Improving CRISPR-cas nuclease specificity using truncated guide RNAs. Nature Biotechnology 32:279-284. doi: 10.1038/nbt.2808.
-
(2014)
Nature Biotechnology
, vol.32
, pp. 279-284
-
-
Fu, Y.1
Sander, J.D.2
Reyon, D.3
Cascio, V.M.4
Joung, J.K.5
-
20
-
-
67349270900
-
Enzymatic assembly of DNA molecules up to several hundred kilobases
-
Gibson DG, Young L, Chuang R-Y, Venter JC, Hutchison CA, Smith HO. 2009. Enzymatic assembly of DNA molecules up to several hundred kilobases. Nature Methods 6:343-345. doi: 10.1038/nmeth.1318.
-
(2009)
Nature Methods
, vol.6
, pp. 343-345
-
-
Gibson, D.G.1
Young, L.2
Chuang, R.-Y.3
Venter, J.C.4
Hutchison, C.A.5
Smith, H.O.6
-
21
-
-
34347206860
-
High-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method
-
Gietz RD, Schiestl RH. 2007. High-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method. Nature Protocols 2:31-34. doi: 10.1038/nprot.2007.13.
-
(2007)
Nature Protocols
, vol.2
, pp. 31-34
-
-
Gietz, R.D.1
Schiestl, R.H.2
-
22
-
-
0034435387
-
A biosensor for the detection of gas toxicity using a recombinant bioluminescent bacterium
-
Gil GC, Mitchell RJ, Chang ST, Gu MB. 2000. A biosensor for the detection of gas toxicity using a recombinant bioluminescent bacterium. Biosensors & Bioelectronics 15:23-30.
-
(2000)
Biosensors & Bioelectronics
, vol.15
, pp. 23-30
-
-
Gil, G.C.1
Mitchell, R.J.2
Chang, S.T.3
Gu, M.B.4
-
23
-
-
84880088705
-
Genome engineering of drosophila with the CRISPR RNA-guided Cas9 nuclease
-
Gratz SJ, Cummings AM, Nguyen JN, Hamm DC, Donohue LK, Harrison MM, Wildonger J, O’Connor-Giles KM. 2013. Genome engineering of drosophila with the CRISPR RNA-guided Cas9 nuclease. Genetics 194:1029-1035. doi: 10.1534/genetics.113.152710.
-
(2013)
Genetics
, vol.194
, pp. 1029-1035
-
-
Gratz, S.J.1
Cummings, A.M.2
Nguyen, J.N.3
Hamm, D.C.4
Donohue, L.K.5
Harrison, M.M.6
Wildonger, J.7
O’connor-Giles, K.M.8
-
24
-
-
84902210542
-
Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification
-
Guilinger JP, Thompson DB, Liu DR. 2014. Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification. Nature Biotechnology 32:577-582. doi: 10.1038/nbt.2909.
-
(2014)
Nature Biotechnology
, vol.32
, pp. 577-582
-
-
Guilinger, J.P.1
Thompson, D.B.2
Liu, D.R.3
-
25
-
-
84899980800
-
The 50:50 method for PCR-based seamless genome editing in yeast
-
Horecka J, Davis RW. 2014. The 50:50 method for PCR-based seamless genome editing in yeast. Yeast 31:103-112. doi: 10.1002/yea.2992.
-
(2014)
Yeast
, vol.31
, pp. 103-112
-
-
Horecka, J.1
Davis, R.W.2
-
26
-
-
80052334922
-
RosettaRemodel: A generalized framework for flexible backbone protein design
-
Huang P-S, Ban Y-EA, Richter F, Andre I, Vernon R, Schief WR, Baker D, Uversky VN. 2011. RosettaRemodel: a generalized framework for flexible backbone protein design. PLoS ONE 6:e24109. doi: 10.1371/journal.pone.0024109.
-
(2011)
Plos ONE
, vol.6
-
-
Huang, P.-S.1
Ban, Y.-E.2
Richter, F.3
Re, I.4
Vernon, R.5
Schief, W.R.6
Baker, D.7
Uversky, V.N.8
-
27
-
-
84872186754
-
Failure to launch
-
Hwang W. 2013. Failure to launch. Nature Biotechnology 31:1-3. doi: 10.1038/nbt.2482.
-
(2013)
Nature Biotechnology
, vol.31
, pp. 1-3
-
-
Hwang, W.1
-
28
-
-
77956972260
-
A general chemical method to regulate protein stability in the mammalian central nervous system
-
Iwamoto M, Bjö rklund T, Lundberg C, Kirik D, Wandless TJ. 2010. A general chemical method to regulate protein stability in the mammalian central nervous system. Chemistry & Biology 17:981-988. doi: 10.1016/j.chembiol.2010.07.009.
-
(2010)
Chemistry & Biology
, vol.17
, pp. 981-988
-
-
Iwamoto, M.1
Bjö Rklund, T.2
Lundberg, C.3
Kirik, D.4
Wandless, T.J.5
-
30
-
-
84942013003
-
A highly characterized yeast toolkit for modular, multipart assembly
-
Lee ME, DeLoache WC, Cervantes B, Dueber JE. 2015. A highly characterized yeast toolkit for modular, multipart assembly. ACS Synthetic Biology 4:975-986. doi: 10.1021/sb500366v.
-
(2015)
ACS Synthetic Biology
, vol.4
, pp. 975-986
-
-
Lee, M.E.1
Deloache, W.C.2
Cervantes, B.3
Dueber, J.E.4
-
31
-
-
0142217880
-
One-step measurement of firefly luciferase activity in yeast
-
Leskinen P, Virta M, Karp M. 2003. One-step measurement of firefly luciferase activity in yeast. Yeast 20:1109-1113. doi: 10.1002/yea.1024.
-
(2003)
Yeast
, vol.20
, pp. 1109-1113
-
-
Leskinen, P.1
Virta, M.2
Karp, M.3
-
32
-
-
0027240004
-
Fusion of GAL4-VP16 to a steroid-binding domain provides a tool for gratuitous induction of galactose-responsive genes in yeast
-
Louvion J-F, Havaux-Copf B, Picard D. 1993. Fusion of GAL4-VP16 to a steroid-binding domain provides a tool for gratuitous induction of galactose-responsive genes in yeast. Gene 131:129-134. doi: 10.1016/0378-1119(93)90681-R.
-
(1993)
Gene
, vol.131
, pp. 129-134
-
-
Louvion, J.-F.1
Havaux-Copf, B.2
Picard, D.3
-
33
-
-
84884160273
-
CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
-
Mali P, Aach J, Stranges PB, Esvelt KM, Moosburner M, Kosuri S, Yang L, Church GM. 2013. CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering. Nature Biotechnology 31:833-838. doi: 10.1038/nbt.2675.
-
(2013)
Nature Biotechnology
, vol.31
, pp. 833-838
-
-
Mali, P.1
Aach, J.2
Stranges, P.B.3
Esvelt, K.M.4
Moosburner, M.5
Kosuri, S.6
Yang, L.7
Church, G.M.8
-
34
-
-
84873734105
-
RNA-guided human genome engineering via Cas9
-
Mali P, Yang L, Esvelt KM, Aach J, Guell M, DiCarlo JE, Norville JE, Church GM. 2013. RNA-guided human genome engineering via Cas9. Science 339:823-826. doi: 10.1126/science.1232033.
-
(2013)
Science
, vol.339
, pp. 823-826
-
-
Mali, P.1
Yang, L.2
Esvelt, K.M.3
Aach, J.4
Guell, M.5
Dicarlo, J.E.6
Norville, J.E.7
Church, G.M.8
-
35
-
-
84922671463
-
Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9
-
Mandal PK, Ferreira LM, Collins R, Meissner TB, Boutwell CL, Friesen M, Vrbanac V, Garrison BS, Stortchevoi A, Bryder D, Musunuru K, Brand H, Tager AM, Allen TM, Talkowski ME, Rossi DJ, Cowan CA. 2014. Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9. Cell Stem Cell 15:643-652. doi: 10.1016/j.stem.2014.10.004.
-
(2014)
Cell Stem Cell
, vol.15
, pp. 643-652
-
-
Mandal, P.K.1
Ferreira, L.M.2
Collins, R.3
Meissner, T.B.4
Boutwell, C.L.5
Friesen, M.6
Vrbanac, V.7
Garrison, B.S.8
Stortchevoi, A.9
Bryder, D.10
Musunuru, K.11
Brand, H.12
Tager, A.M.13
Allen, T.M.14
Talkowski, M.E.15
Rossi, D.J.16
Cowan, C.A.17
-
37
-
-
84982358134
-
A revised medium for rapid growth and bio assays with tobacco tissue cultures
-
Murashige T, Skoog F. 1962. A revised medium for rapid growth and bio assays with tobacco tissue cultures. Physiologia Plantarum 15:473-497. doi: 10.1111/j.1399-3054.1962.tb08052.x.
-
(1962)
Physiologia Plantarum
, vol.15
, pp. 473-497
-
-
Murashige, T.1
Skoog, F.2
-
38
-
-
84858030373
-
Fluorescence imaging of cellular metabolites with RNA
-
Paige JS, Nguyen-Duc T, Song W, Jaffrey SR. 2012. Fluorescence imaging of cellular metabolites with RNA. Science 335:1194. doi: 10.1126/science.1218298.
-
(2012)
Science
, vol.335
, pp. 1194
-
-
Paige, J.S.1
Nguyen-Duc, T.2
Song, W.3
Jaffrey, S.R.4
-
39
-
-
84884155038
-
High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity
-
Pattanayak V, Lin S, Guilinger JP, Ma E, Doudna JA, Liu DR. 2013. High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity. Nature Biotechnology 31:839-843. doi: 10.1038/nbt.2673.
-
(2013)
Nature Biotechnology
, vol.31
, pp. 839-843
-
-
Pattanayak, V.1
Lin, S.2
Guilinger, J.P.3
Ma, E.4
Doudna, J.A.5
Liu, D.R.6
-
40
-
-
84925534357
-
A light-inducible CRISPR-Cas9 system for control of endogenous gene activation
-
Polstein LR, Gersbach CA. 2015. A light-inducible CRISPR-Cas9 system for control of endogenous gene activation. Nature Chemical Biology 11:198-200. doi: 10.1038/nchembio.1753.
-
(2015)
Nature Chemical Biology
, vol.11
, pp. 198-200
-
-
Polstein, L.R.1
Gersbach, C.A.2
-
43
-
-
84884288934
-
Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity
-
Ran FA, Hsu PD, Lin C-Y, Gootenberg JS, Konermann S, Trevino AE, Scott DA, Inoue A, Matoba S, Zhang Y, Zhang F. 2013. Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity. Cell 154: 1380-1389. doi: 10.1016/j.cell.2013.08.021.
-
(2013)
Cell
, vol.154
, pp. 1380-1389
-
-
Ran, F.A.1
Hsu, P.D.2
Lin, C.-Y.3
Gootenberg, J.S.4
Konermann, S.5
Trevino, A.E.6
Scott, D.A.7
Inoue, A.8
Matoba, S.9
Zhang, Y.10
Zhang, F.11
-
44
-
-
33845509639
-
Dual function of an arabidopsis transcription factor DREB2A in water-stress-responsive and heat-stress-responsive gene expression
-
Sakuma Y, Maruyama K, Qin F, Osakabe Y, Shinozaki K, Yamaguchi-Shinozaki K. 2006. Dual function of an arabidopsis transcription factor DREB2A in water-stress-responsive and heat-stress-responsive gene expression. Proceedings of the National Academy of Sciences of the United States of America 103:18822-18827. doi: 10.1073/pnas.0605639103.
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, pp. 18822-18827
-
-
Sakuma, Y.1
Maruyama, K.2
Qin, F.3
Osakabe, Y.4
Shinozaki, K.5
Yamaguchi-Shinozaki, K.6
-
45
-
-
84890033064
-
Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients
-
Schwank G, Koo B-K, Sasselli V, Dekkers JF, Heo I, Demircan T, Sasaki N, Boymans S, Cuppen E, van der Ent CK, Nieuwenhuis EES, Beekman JM, Clevers H. 2013. Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients. Cell Stem Cell 13:653-658. doi: 10.1016/j.stem.2013.11.002.
-
(2013)
Cell Stem Cell
, vol.13
, pp. 653-658
-
-
Schwank, G.1
Koo, B.-K.2
Sasselli, V.3
Dekkers, J.F.4
Heo, I.5
Demircan, T.6
Sasaki, N.7
Boymans, S.8
Cuppen, E.9
Van Der Ent, C.K.10
Nieuwenhuis, E.11
Beekman, J.M.12
Clevers, H.13
-
46
-
-
84878663807
-
Broadly applicable methodology for the rapid and dosable small molecule-mediated regulation of transcription factors in human cells
-
Shoulders MD, Ryno LM, Cooley CB, Kelly JW, Wiseman RL. 2013. Broadly applicable methodology for the rapid and dosable small molecule-mediated regulation of transcription factors in human cells. Journal of the American Chemical Society 135:8129-8132. doi: 10.1021/ja402756p.
-
(2013)
Journal of the American Chemical Society
, vol.135
, pp. 8129-8132
-
-
Shoulders, M.D.1
Ryno, L.M.2
Cooley, C.B.3
Kelly, J.W.4
Wiseman, R.L.5
-
47
-
-
0037313962
-
Total biosynthesis of hydrocortisone from a simple carbon source in yeast
-
Szczebara FM, Chandelier C, Villeret C, Masurel A, Bourot S, Duport C, Blanchard S, Groisillier A, Testet E, Costaglioli P, Cauet G, Degryse E, Balbuena D, Winter J, Achstetter T, Spagnoli R, Pompon D, Dumas B. 2003. Total biosynthesis of hydrocortisone from a simple carbon source in yeast. Nature Biotechnology 21:143-149. doi: 10.1038/nbt775.
-
(2003)
Nature Biotechnology
, vol.21
, pp. 143-149
-
-
Szczebara, F.M.1
Chandelier, C.2
Villeret, C.3
Masurel, A.4
Bourot, S.5
Duport, C.6
Blanchard, S.7
Groisillier, A.8
Testet, E.9
Costaglioli, P.10
Cauet, G.11
Degryse, E.12
Balbuena, D.13
Winter, J.14
Achstetter, T.15
Spagnoli, R.16
Pompon, D.17
Dumas, B.18
-
48
-
-
79251580632
-
Design and application of a mevalonate-responsive regulatory protein
-
Tang S-Y, Cirino PC. 2011. Design and application of a mevalonate-responsive regulatory protein. Angewandte Chemie International Edition 50:1084-1086. doi: 10.1002/anie.201006083.
-
(2011)
Angewandte Chemie International Edition
, vol.50
, pp. 1084-1086
-
-
Tang, S.-Y.1
Cirino, P.C.2
-
49
-
-
84879999713
-
Screening for enhanced triacetic acid lactone production by recombinant escherichia coli expressing a designed triacetic acid lactone reporter
-
Tang S-Y, Qian S, Akinterinwa O, Frei CS, Gredell JA, Cirino PC. 2013. Screening for enhanced triacetic acid lactone production by recombinant escherichia coli expressing a designed triacetic acid lactone reporter. Journal of the American Chemical Society 135:10099-10103. doi: 10.1021/ja402654z.
-
(2013)
Journal of the American Chemical Society
, vol.135
, pp. 10099-10103
-
-
Tang, S.-Y.1
Qian, S.2
Akinterinwa, O.3
Frei, C.S.4
Gredell, J.A.5
Cirino, P.C.6
-
50
-
-
84884166196
-
Computational design of ligand-binding proteins with high affinity and selectivity
-
Tinberg CE, Khare SD, Dou J, Doyle L, Nelson JW, Schena A, Jankowski W, Kalodimos CG, Johnsson K, Stoddard BL, Baker D. 2013. Computational design of ligand-binding proteins with high affinity and selectivity. Nature 501:212-216. doi: 10.1038/nature12443.
-
(2013)
Nature
, vol.501
, pp. 212-216
-
-
Tinberg, C.E.1
Khare, S.D.2
Dou, J.3
Doyle, L.4
Nelson, J.W.5
Schena, A.6
Jankowski, W.7
Kalodimos, C.G.8
Johnsson, K.9
Stoddard, B.L.10
Baker, D.11
-
51
-
-
0036776124
-
Sequence and structural differences between enzyme and nonenzyme homologs
-
Todd AE, Orengo CA, Thornton JM. 2002. Sequence and structural differences between enzyme and nonenzyme homologs. Structure 10:1435-1451. doi: 10.1016/S0969-2126(02)00861-4.
-
(2002)
Structure
, vol.10
, pp. 1435-1451
-
-
Todd, A.E.1
Orengo, C.A.2
Thornton, J.M.3
-
52
-
-
84902204289
-
Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing
-
Tsai SQ, Wyvekens N, Khayter C, Foden JA, Thapar V, Reyon D, Goodwin MJ, Aryee MJ, Joung JK. 2014. Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing. Nature Biotechnology 32:569-576. doi: 10.1038/nbt.2908.
-
(2014)
Nature Biotechnology
, vol.32
, pp. 569-576
-
-
Tsai, S.Q.1
Wyvekens, N.2
Khayter, C.3
Foden, J.A.4
Thapar, V.5
Reyon, D.6
Goodwin, M.J.7
Aryee, M.J.8
Joung, J.K.9
-
53
-
-
0034754163
-
A yeast sensor of ligand binding
-
Tucker CL, Fields S. 2001. A yeast sensor of ligand binding. Nature Biotechnology 19:1042-1046. doi: 10.1038/nbt1101-1042.
-
(2001)
Nature Biotechnology
, vol.19
, pp. 1042-1046
-
-
Tucker, C.L.1
Fields, S.2
-
54
-
-
84890050551
-
Correction of a genetic disease in mouse via use of CRISPR-Cas9
-
Wu Y, Liang D, Wang Y, Bai M, Tang W, Bao S, Yan Z, Li D, Li J. 2013. Correction of a genetic disease in mouse via use of CRISPR-Cas9. Cell Stem Cell 13:659-662. doi: 10.1016/j.stem.2013.10.016.
-
(2013)
Cell Stem Cell
, vol.13
, pp. 659-662
-
-
Wu, Y.1
Liang, D.2
Wang, Y.3
Bai, M.4
Tang, W.5
Bao, S.6
Yan, Z.7
Li, D.8
Li, J.9
-
55
-
-
37249038595
-
A comparative study examining the cytotoxicity of inducible gene expression system ligands in different cell types
-
Xie J, Nair A, Hermiston TW. 2008. A comparative study examining the cytotoxicity of inducible gene expression system ligands in different cell types. Toxicology in Vitro 22:261-266. doi: 10.1016/j.tiv.2007.08.019.
-
(2008)
Toxicology in Vitro
, vol.22
, pp. 261-266
-
-
Xie, J.1
Nair, A.2
Hermiston, T.W.3
-
56
-
-
84879164975
-
Synthetic RNA devices to expedite the evolution of metabolite-producing microbes
-
Yang J, Seo SW, Jang S, Shin S-I, Lim CH, Roh T-Y, Jung GY. 2013. Synthetic RNA devices to expedite the evolution of metabolite-producing microbes. Nature Communications 4:1413. doi: 10.1038/ncomms2404.
-
(2013)
Nature Communications
, vol.4
, pp. 1413
-
-
Yang, J.1
Seo, S.W.2
Jang, S.3
Shin, S.-I.4
Lim, C.H.5
Roh, T.-Y.6
Jung, G.Y.7
-
57
-
-
84872001455
-
Pharmaceutically controlled designer circuit for the treatment of the metabolic syndrome
-
Ye H, Charpin-El Hamri G, Zwicky K, Christen M, Folcher M, Fussenegger M. 2013. Pharmaceutically controlled designer circuit for the treatment of the metabolic syndrome. Proceedings of the National Academy of Sciences of the United States of America 110:141-146. doi: 10.1073/pnas.1216801110.
-
(2013)
Proceedings of the National Academy of Sciences of the United States of America
, vol.110
, pp. 141-146
-
-
Ye, H.1
Charpin-El Hamri, G.2
Zwicky, K.3
Christen, M.4
Folcher, M.5
Fussenegger, M.6
-
58
-
-
34447099171
-
Arabidopsis mesophyll protoplasts: A versatile cell system for transient gene expression analysis
-
Yoo S-D, Cho Y-H, Sheen J. 2007. Arabidopsis mesophyll protoplasts: a versatile cell system for transient gene expression analysis. Nature Protocols 2:1565-1572. doi: 10.1038/nprot.2007.199.
-
(2007)
Nature Protocols
, vol.2
, pp. 1565-1572
-
-
Yoo, S.-D.1
Cho, Y.-H.2
Sheen, J.3
-
59
-
-
84923297110
-
A split-Cas9 architecture for inducible genome editing and transcription modulation
-
Zetsche B, Volz SE, Zhang F. 2015. A split-Cas9 architecture for inducible genome editing and transcription modulation. Nature Biotechnology 33:139-142. doi: 10.1038/nbt.3149.
-
(2015)
Nature Biotechnology
, vol.33
, pp. 139-142
-
-
Zetsche, B.1
Volz, S.E.2
Zhang, F.3
-
60
-
-
84859633048
-
Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids
-
Zhang F, Carothers JM, Keasling JD. 2012. Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids. Nature Biotechnology 30:354-359. doi: 10.1038/nbt.2149.
-
(2012)
Nature Biotechnology
, vol.30
, pp. 354-359
-
-
Zhang, F.1
Carothers, J.M.2
Keasling, J.D.3
-
61
-
-
79959913313
-
Biosensors and their applications in microbial metabolic engineering
-
Zhang F, Keasling J. 2011. Biosensors and their applications in microbial metabolic engineering. Trends in Microbiology 19:323-329. doi: 10.1016/j.tim.2011.05.003.
-
(2011)
Trends in Microbiology
, vol.19
, pp. 323-329
-
-
Zhang, F.1
Keasling, J.2
|