Construction of lycopene-overproducing E. coli strains by combining systematic and combinatorial gene knockout targets

Nature Biotechnology

Volumn 23, Issue 5, 2005, Pages 612-616

  Alper, Hal ^a   Miyaoku, Kohei ^a   Stephanopoulos, Gregory ^a  

^a Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOTECHNOLOGY; ESCHERICHIA COLI; METABOLISM;

METABOLIC ENGINEERING; REGULATORY MECHANISMS;

GENES;

LYCOPENE; RECOMBINANT PROTEIN; CAROTENOID;

ARTICLE; BACTERIAL STRAIN; BIOSYNTHESIS; CONTROLLED STUDY; ESCHERICHIA COLI; GENE IDENTIFICATION; GENE TARGETING; KNOCKOUT GENE; METHODOLOGY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; STOICHIOMETRY; WILD TYPE; BIOLOGICAL MODEL; CLASSIFICATION; COMPUTER SIMULATION; GENE SILENCING; GENETIC ENHANCEMENT; GENETICS; LETTER; METABOLISM; PROTEIN ENGINEERING; SPECIES DIFFERENCE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

CAROTENOIDS; COMPUTER SIMULATION; ESCHERICHIA COLI; GENE SILENCING; GENE TARGETING; GENETIC ENHANCEMENT; MODELS, BIOLOGICAL; PROTEIN ENGINEERING; RECOMBINANT PROTEINS; SPECIES SPECIFICITY;

EID: 22844452835     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt1083     Document Type: Article

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