Broadly applicable methodology for the rapid and dosable small molecule-mediated regulation of transcription factors in human cells

Journal of the American Chemical Society

Volumn 135, Issue 22, 2013, Pages 8129-8132

  Shoulders, Matthew D ^a,b   Ryno, Lisa M ^a   Cooley, Christina B ^a   Kelly, Jeffery W ^a   Wiseman, R Luke ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONAL CONTROL; PHYSIOLOGIC LEVELS; PROTEIN DEGRADATION; REGULATION OF TRANSCRIPTION; THERAPEUTIC IMPACT; TRANSCRIPTIONAL ACTIVATIONS; TRANSCRIPTIONAL PROGRAM; TRANSCRIPTIONAL RESPONSE;

CYTOLOGY; MOLECULES; PHYSIOLOGY;

TRANSCRIPTION FACTORS;

TRANSCRIPTION FACTOR;

ARTICLE; CELL FUNCTION; GENETIC TRANSCRIPTION; MOLECULAR BIOLOGY; MOLECULAR DYNAMICS; PROTEIN CONFORMATION; PROTEIN DEGRADATION; TRANSCRIPTION REGULATION;

DNA-BINDING PROTEINS; HEK293 CELLS; HUMANS; MOLECULAR STRUCTURE; TACROLIMUS BINDING PROTEIN 1A; TRANSCRIPTION FACTORS;

EID: 84878663807     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja402756p     Document Type: Article

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