On the translocation of botulinum and tetanus neurotoxins across the membrane of acidic intracellular compartments

Biochimica et Biophysica Acta - Biomembranes

Volumn 1858, Issue 3, 2016, Pages 467-474

  Pirazzini, Marco ^a   Tehran, Domenico Azarnia ^a   Leka, Oneda ^a   Zanetti, Giulia ^a   Rossetto, Ornella ^a   Montecucco, Cesare ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Botulinum neurotoxin isoforms; Clostridia; Duration of neuroparalysis; Endocytosis; Presynaptic binding; Translocation

Indexed keywords

BOTULINUM TOXIN; METALLOPROTEINASE; SNARE PROTEIN; TETANUS TOXIN;

CATALYSIS; CELL MEMBRANE TRANSPORT; CYTOSOL; ENDOSOME; ENZYME SPECIFICITY; INTERNALIZATION; MEMBRANE BINDING; NEUROTOXICITY; NONHUMAN; PRESYNAPTIC MEMBRANE; PRIORITY JOURNAL; RECEPTOR BINDING; REVIEW; TOXIN STRUCTURE; ANIMAL; CELL MEMBRANE; CHEMISTRY; ENDOCYTOSIS; HUMAN; METABOLISM; MOUSE; NERVE ENDING; PH; PROTEIN TRANSPORT; STRUCTURE ACTIVITY RELATION;

ANIMALS; BOTULINUM TOXINS; CELL MEMBRANE; ENDOCYTOSIS; HUMANS; HYDROGEN-ION CONCENTRATION; MICE; PRESYNAPTIC TERMINALS; PROTEIN TRANSPORT; SNARE PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TETANUS TOXIN;

EID: 84956579271     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2015.08.014     Document Type: Review

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