The adsorption of Pseudomonas aeruginosa exotoxin A to phospholipid monolayers is controlled by pH and surface potential

Biophysical Journal

Volumn 73, Issue 3, 1997, Pages 1468-1478

  Nordera, Paola ^a   Dalla Serra, Mauro ^a   Menestrina, Gianfranco ^a  

^a CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHOLIPID; PSEUDOMONAS EXOTOXIN;

ADSORPTION; ARTICLE; CONFORMATION; DESORPTION; DISSOCIATION CONSTANT; IONIC STRENGTH; LIPID MEMBRANE; MEMBRANE BINDING; MEMBRANE COMPONENT; MEMBRANE POTENTIAL; PH;

PSEUDOMONAS; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS EXOTOXIN;

EID: 0343471423     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(97)78179-7     Document Type: Article

References (45)

1. Allured, V. S., R. J. Collier, S. F. Carroll, and D. B. McKay. 1986. Structure of exotoxin A of Pseudomonas aeruginosa at 3.0-Ångstrom resolution. Proc. Natl. Acad. Sci. USA. 83:1320-1324.
2. Aveyard, R., and D. A. Haydon. 1973. An Introduction to the Principles of Surface Chemistry. Cambridge University Press, Cambridge.
3. Bougis, P., H. Rochat, G. Pieroni, and R. Verger. 1981. Penetration of phospholipid monolayers by cardiotoxins. Biochemistry. 20:4915-4920.
4. Cevc, G. 1990. Membrane electrostatics. Biochim. Biophys. Acta. 1031-3: 311-382.
5. Connor, J., C. Bucana, I. J. Fidler, and A. J. Schroit. 1989. Differentiation-dependent expression of phosphatidylserine in mammalian plasma membranes: quantitative assesment of outer-leaflet lipid by prothrom-binase complex formation. Proc. Natl. Acad. Sci. USA. 86:3184-3188.
6. Demel, R., G. Schiavo, B. de Kruijff, and C. Montecucco. 1991. Lipid interaction of diphtheria toxin and mutants. A study with phospholipids and protein monolayers. Eur. J. Biochem. 197:481-486.
7. Eisenberg, M., T. Gresalfi, T. Riccio, and S. McLaughlin. 1979. Adsorption of monovalent cations to bilayer membranes containing negative phospholipids. Biochemistry. 18:5213-5223.
8. Farahbakhsh, Z. T., R. L. Baldwin, and B. J. Wisnieski. 1986. Pseudomonas exotoxin A. Membrane binding, insertion, and traversal. J. Biol. Chem. 261:11404-11408.
9. Farahbakhsh, Z. T., and B. J. Wisnieski. 1989. The acid-triggered entry pathway of Pseudomonas exotoxin A. Biochemistry. 28:580-585.
10. Frenette, M., M. Knibiehler, D. Baty, V. Geli, F. Pattus, R. Verger, and C. Lazdunski. 1989. Interactions of Colicin A domains with phospholipid monolayers and liposomes: relevance to the mechanism of action. Biochemistry. 28:2509-2514.
11. Fryling, C., F. Ogata, and D. FitzGerald. 1992. Characterization of a cellular protease that cleaves Pseudomonas exotoxin. Infect. Immun. 60:497-502.
12. Gambale, F., G. Rauch, G. Belmonte, and G. Menestrina. 1992. Properties of Pseudomonas aeruginosa exotoxin A ionic channel incorporated in planar lipid bilayers. FEBS Lett. 306:41-45.
13. Gascard, P., D. Tran, M. Sauvage, J. C. Sulpice, K. Fukami, T. Takenawa, M. Claret, and F. Giraud. 1991. Asymmetric distribution of phosphoinositides and phosphatidic acid in the human erythrocyte membrane. Biochim. Biophys. Acta. 1069:27-36.
14. Gruenberg, J., and K. E. Howell. 1989. Membrane traffic in endocytosis: insights from cell-free assays. Annu. Rev. Cell Biol. 5:453-481.
15. Gutman, M., and E. Nachliel. 1985. Kinetic analysis of protonation of a specific site on a buffered surface of a macromolecular body. Biochemistry. 24:2941-2946.
16. Gutman, M., E. Nachliel, E. Gershon, and R. Giniger. 1983. Kinetic analysis of the protonation of a surface group of a macromolecule. Eur. J. Biochem. 134:63-69.
17. Heymann, J. B., S. D. Zakharov, Y.-L. Zhang, and W. A. Cramer. 1996. Characterization of electrostatic and nonelectrostatic components of protein-membrane binding interactions. Biochemistry. 35:2717-2725.
18. Iglewski, B. H., and D. Kabat. 1975. NAD-dependent inhibition of protein synthesis by Pseudomonas aeruginosa toxin. Proc. Natl. Acad. Sci. USA. 72:2284-2288.
19. Iglewski, B. H., P. V. Liu, and D. Kabat. 1977. Mechanism of action of Pseudomonas aeruginosa exotoxin A: adenosine diphosphateribosylation of mammalian elongation factor 2 in vitro and in vivo. Infect. Immun. 15:138-144.
20. Jiang, J. X., and E. London. 1990. Involvement of denaturation-like changes in Pseudomonas exotoxin A hydrophobicity and membrane penetration determined by characterization of pH and thermal transitions. Roles of two distinct conformationally altered states. J. Biol. Chem. 265:8636-8641.
21. 2-macroglobulin receptor/ low density lipoprotein receptor-related protein binds and internalizes Pseudomonas exotoxin A. J. Biol. Chem. 267:12420-12423.
22. Liu, P. V. 1974. Extracellular toxins of Pseudomonas aeruginosa. J. Infect. Dis. 130:94-99.
23. Madshus, I. H., and R. J. Collier. 1989. Effects of eliminating a disulfide bridge within domain II of Pseudomonas aeruginosa exotoxin A. Infect. Immun. 57:1873-1878.
24. McDaniel, R. V., A. McLaughlin, A. P. Winiski, M. Eisenberg, and S. McLaughlin. 1984. Bilayer membranes containing the ganglioside GM1: models for electrostatic potentials adjacent to biological membranes. Biochemistry. 23:4618-4624.
25. Menestrina, G., C. Pederzolli, S. Forti, and F. Gambale. 1991. Lipid interaction of Pseudomonas aeruginosa exotoxin A: acid triggered aggregation and permeabilization of lipid vesicles. Biophys. J. 60: 1388-1400.
26. Montecucco, C., E. Papini, and G. Schiavo. 1994. Bacterial protein toxins penetrate cells via a four-step mechanism. FEBS Lett. 346:92-98.
27. Montecucco, C., and G. Schiavo. 1995. Structure and function of tetanus and botulinum neurotoxins. Q. Rev. Biophys. 28:423-472.
28. Ogata, M., V. K. Chaudhary, I. Pastan, and D. J. FitzGerald. 1990. Processing of Pseudomonas exotoxin by a cellular protease results in the generation of a 37,000-Da toxin fragment that is translocated to the cytosol. J. Biol. Chem. 265:20678-20685.
29. 280 generates the enzymatically active fragment which translocates to the cytosol. J. Biol. Chem. 267:25396-25401.
30. Olsnes, S., H. Stenmark, J. Ø. Moskaug, S. McGill, I. H. Madshus, and K. Sandvig. 1990. Protein toxins with intracellular targets. Microb. Pathog. 8:163-168.
31. Op den Kamp, J. A. F. 1979. Lipid asimmetry in membranes. Annu. Rev. Biochem. 48:47-71.
32. Pastan, I., V. K. Chaudhary, and D. J. FitzGerald. 1992. Recombinant toxins as novel therapeutic agents. Annu. Rev. Biochem. 61:331-354.
33. Pattus, F., M. C. Martinez, B. Dargent, D. Cavard, R. Verger, and C. Lazdunski. 1983. Interaction of Colicin A with phospholipid monolayers and liposomes. Biochemistry. 22:5698-5703.
34. Pier, G. B., G. J. Small, and H. B. Warren. 1990. Protection against mucoid Pseudomonas aeruginosa in rodent models of endobronchial infections. Science. 249:537-540.
35. Rahme, L. G., E. J. Stevens, S. F. Wolfort, J. Shao, R. G. Tompkins, and F. M. Ausubel. 1995. Common virulence factors for bacterial pathogenicity in plants and animals. Science. 268:1899-1902.
36. Rasper, D. M., and A. R. Merrill. 1994. Evidence for the modulation of Pseudomonas aeruginosa exotoxin A-induced pore formation by membrane surface charge density. Biochemistry. 33:12981-12989.
37. Sandvig, K., and J. Ø. Moskaug. 1987. Pseudomonas toxin binds Triton X-114 at low pH. Biochem. J. 245:899-901.
38. Schiavo, G., R. Demel, and C. Montecucco. 1991. On the role of polysialoglycosphingolipids as tetanus toxin receptors. Eur. J. Biochem. 199: 705-711.
39. Seelig, A. 1990. Substance P and antagonists. Surface activity and molecular shapes. Biochim. Biophys. Acta. 1030:111-118.
40. Siegall, C. B., V. K. Chaudhary, D. J. FitzGerald, and I. Pastan. 1989. Functional analysis of domains II, Ib, and III of Pseudomonas exotoxin. J. Biol. Chem. 264:14256-14261.
41. Tamm, L. K., and I. Bartoldus. 1988. Antibody binding to lipid model membranes. The large ligand effect. Biochemistry. 27:7453-7458.
42. Verger, R., and G. H. de Haas. 1976. Interfacial enzyme kinetics of lipolysis. Annu. Rev. Biophys. Bioeng. 5:77-117.
43. Wick, M. J., D. W. Frank, D. G. Storey, and B. H. Iglewski. 1990. Structure, function, and regulation of Pseudomonas aeruginosa exotoxin A. Annu. Rev. Microbiol 44:335-363.
44. Woods, D. E., and B. H. Iglewski. 1983. Toxins of Pseudomonas aeruginosa: new perspectives. Rev. Infect. Dis. 5:715-722.
45. Zalman, L. S., and B. J. Wisnieski. 1985. Characterization of the insertion of Pseudomonas exotoxin A into membranes. Infect. Immun. 50: 630-635.