Synchronized chaperone function of botulinum neurotoxin domains mediates light chain translocation into neurons

Current Topics in Microbiology and Immunology

Volumn 364, Issue , 2013, Pages 115-137

  Fischer, Audrey ^a  

^a JOHNS HOPKINS UNIVERSITY APPLIED PHYSICS LABORATORY   (United States)

Author keywords

Botulinum neurotoxin; Channels; Chaperones; Membranes; Protein translocation

Indexed keywords

BACTERIAL PROTEIN; BOTULINUM TOXIN; CHAPERONE; HEMAGGLUTININ; NONTOXIC NONHEMAGGLUTININ PROTEIN; SNARE PROTEIN; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; GANGLIOSIDE RECEPTOR; ION CHANNEL; NEUROTOXIN;

ACIDITY; ARTICLE; BOTULISM; CELL MEMBRANE CONDUCTANCE; CELL MEMBRANE TRANSPORT; CHANNEL GATING; CHOLINERGIC NERVE CELL; CRYSTAL STRUCTURE; CYTOSOL; ENDOCYTOSIS; ENDOSOME; HEAVY CHAIN; INTERNALIZATION; INTESTINE EPITHELIUM; LIGHT CHAIN; LIPID BILAYER; MEMBRANE DAMAGE; NERVE CELL; NEUROTOXICITY; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN POLYMERIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN REFOLDING; PROTEIN STRUCTURE; PROTEIN TRANSPORT; RECEPTOR BINDING; SYNAPSE VESICLE; SYNAPTIC INHIBITION; TOXIN STRUCTURE; TRANSCYTOSIS; ANIMAL; CELL MEMBRANE; CLOSTRIDIUM BOTULINUM; ELECTROPHYSIOLOGY; ENZYME ACTIVATION; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PH; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; PROTEIN UNFOLDING;

ANIMALS; BOTULINUM TOXINS; BOTULISM; CELL MEMBRANE; CLOSTRIDIUM BOTULINUM; CYTOSOL; ELECTROPHYSIOLOGICAL PHENOMENA; ENDOCYTOSIS; ENDOSOMES; ENZYME ACTIVATION; HYDROGEN-ION CONCENTRATION; ION CHANNELS; LIPID BILAYERS; MOLECULAR CHAPERONES; NEURONS; NEUROTOXINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; PROTEIN UNFOLDING; PROTEOLYSIS; RECEPTORS, CELL SURFACE; SNARE PROTEINS;

EID: 84875808763     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-33570-9-6     Document Type: Article

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