Receptor and substrate interactions of clostridial neurotoxins

Toxicon

Volumn 54, Issue 5, 2009, Pages 550-560

  Brunger, Axel T ^a   Rummel, Andreas ^b  

^a STANFORD UNIVERSITY   (United States)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Botulinum neurotoxin; Ganglioside; Neurotransmission; Protease; SNARE; Synaptic vesicle; Synaptotagmin

Indexed keywords

BOTULINUM ANTISERUM; BOTULINUM TOXIN A; BOTULINUM TOXIN B; BOTULINUM TOXIN E; CLOSTRIDIUM TOXIN; GANGLIOSIDE GD 1A; GANGLIOSIDE GM3; GANGLIOSIDE GT 1B; HYDROXAMIC ACID DERIVATIVE; MEMBRANE PROTEIN; N ACETYLGALACTOSAMINE; PROTEIN A; PROTEINASE; PROTEINASE INHIBITOR; SNARE PROTEIN; SYNAPTIC VESICLE GLYCOPROTEIN 2; SYNAPTOBREVIN 2; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; SYNAPTOTAGMIN I; SYNAPTOTAGMIN II; TETANUS TOXIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CHOLINERGIC NERVE CELL; CRYSTAL STRUCTURE; DRUG PROTEIN BINDING; ENDOCYTOSIS; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; EXOCYTOSIS; HEAVY CHAIN; LIGHT CHAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN CLEAVAGE; PROTEIN CROSS LINKING; PROTEIN DOMAIN; PROTEIN HYDROLYSIS; PROTEIN TRANSPORT; RECEPTOR BINDING; SYNAPSE VESICLE; SYNAPTOSOME; TOXIN ANALYSIS; TOXIN STRUCTURE;

ANIMALS; BOTULINUM TOXINS; CHOLINERGIC FIBERS; GANGLIOSIDES; HUMANS; MOTOR NEURONS; NEUROTOXINS; PROTEIN BINDING; SNARE PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SYNAPTIC MEMBRANES; SYNAPTOTAGMINS; TETANUS TOXIN;

EID: 68949179783     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2008.12.027     Document Type: Article

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