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Volumn 146, Issue , 2016, Pages 404-417

Prefrontal white matter pathology in air pollution exposed Mexico City young urbanites and their potential impact on neurovascular unit dysfunction and the development of Alzheimer's disease

Author keywords

Air pollution; Alzheimer; BBB; Children; Dogs; Endothelial damage; Nanosize particles; Neurovascular unit; PM2.5; Tight junctions

Indexed keywords

AMYLOID; LIPID; LIPOFUSCIN; NANOPARTICLE;

EID: 84956566947     PISSN: 00139351     EISSN: 10960953     Source Type: Journal    
DOI: 10.1016/j.envres.2015.12.031     Document Type: Article
Times cited : (158)

References (105)
  • 4
    • 84920568095 scopus 로고    scopus 로고
    • You shall not pass" - tight junctions of the blood brain barrier
    • Bauer H.C., Krizbai I.A., Bauer H., Traweger A. You shall not pass" - tight junctions of the blood brain barrier. Front. Neurosci. 2014, 8:392. 10.3389/fnins.2014.00392.
    • (2014) Front. Neurosci. , vol.8 , pp. 392
    • Bauer, H.C.1    Krizbai, I.A.2    Bauer, H.3    Traweger, A.4
  • 5
    • 84952664451 scopus 로고    scopus 로고
    • Vascular toxicity of ultra-small TiO2 nanoparticles and single walled carbon nanotubes and in vivo
    • Bayat N., Lopes V.R., Schölermann J., Jensen L.D., Cristobal S. Vascular toxicity of ultra-small TiO2 nanoparticles and single walled carbon nanotubes and in vivo. Biomaterials 2015, 63:1-13. 10.1016/j.biomaterials.2015.05.044.
    • (2015) Biomaterials , vol.63 , pp. 1-13
    • Bayat, N.1    Lopes, V.R.2    Schölermann, J.3    Jensen, L.D.4    Cristobal, S.5
  • 6
    • 84898857802 scopus 로고    scopus 로고
    • Nanoparticle toxicity by the gastrointestinal route: evidence and knowledge gaps
    • Bergin I.L., Witzmann F.A. Nanoparticle toxicity by the gastrointestinal route: evidence and knowledge gaps. Int. J. Biomed. Nanosci. Nanotechnol. 2013, 3:1-2. 10.1504/IJBNN.2013.054515.
    • (2013) Int. J. Biomed. Nanosci. Nanotechnol. , vol.3 , pp. 1-2
    • Bergin, I.L.1    Witzmann, F.A.2
  • 7
    • 0041696686 scopus 로고    scopus 로고
    • Air pollution levels and trends in the México City metropolitan area." Chapter 6. In: urban air pollution and forest: resources at risk in the Mexico City air
    • Springer-Verlag, New York, M.F. Basin, L. de Bauer, T. Hernández (Eds.)
    • Bravo-Alvarez H., Torres-Jardón R. Air pollution levels and trends in the México City metropolitan area." Chapter 6. In: urban air pollution and forest: resources at risk in the Mexico City air. Ecological Studies 2002, 156:121-159. Springer-Verlag, New York. M.F. Basin, L. de Bauer, T. Hernández (Eds.).
    • (2002) Ecological Studies , vol.156 , pp. 121-159
    • Bravo-Alvarez, H.1    Torres-Jardón, R.2
  • 11
    • 84976895131 scopus 로고    scopus 로고
    • Perry CSF biomarkers: low amyloid-β 1-42 and BDNF and high IFN γ differentiate children exposed to Mexico City high air pollution v controls. Alzheimer's Disease Uncertainties
    • Calderón-Garcidueñas L., Franco-Lira M., Rodríguez-Díaz J., Chao C., Tompson C., Mukherjee P.S. Perry CSF biomarkers: low amyloid-β 1-42 and BDNF and high IFN γ differentiate children exposed to Mexico City high air pollution v controls. Alzheimer's Disease Uncertainties. J. Alzheimer Dis. 2015, 5:2. 10.4172/2161-0460.1000189.
    • (2015) J. Alzheimer Dis. , vol.5 , pp. 2
    • Calderón-Garcidueñas, L.1    Franco-Lira, M.2    Rodríguez-Díaz, J.3    Chao, C.4    Tompson, C.5    Mukherjee, P.S.6
  • 20
    • 84930934685 scopus 로고    scopus 로고
    • Mexico City normal weight children exposed to High concentrations of ambient PM2.5 show High blood leptin and endothelin-1, vitamin D deficiency, and food reward hormone dysregulation versus low pollution controls. Relevance for obesity and Alzheimer disease
    • Calderón-Garcidueñas L., Franco-Lira M., D'Angiulli A., Rodriguez-Diaz J., Blaurock-Busch E., Busch I., Chao C.K., Thompson C., Mukherjee P.S., Torres-Jardón R., Perry G. Mexico City normal weight children exposed to High concentrations of ambient PM2.5 show High blood leptin and endothelin-1, vitamin D deficiency, and food reward hormone dysregulation versus low pollution controls. Relevance for obesity and Alzheimer disease. Environ. Res. 2015, 140:579-592.
    • (2015) Environ. Res. , vol.140 , pp. 579-592
    • Calderón-Garcidueñas, L.1    Franco-Lira, M.2    D'Angiulli, A.3    Rodriguez-Diaz, J.4    Blaurock-Busch, E.5    Busch, I.6    Chao, C.K.7    Thompson, C.8    Mukherjee, P.S.9    Torres-Jardón, R.10    Perry, G.11
  • 31
    • 84881071590 scopus 로고    scopus 로고
    • Correlative ultrastructural investigations of airway epithelium following experimental exposure to defined air pollutants and lifestyle exposure to tobacco smoke
    • Carson J.L., Brighton L.E., Collier A.M., Bromberg P.A. Correlative ultrastructural investigations of airway epithelium following experimental exposure to defined air pollutants and lifestyle exposure to tobacco smoke. Inhal. Toxicol. 2013, 25:134-140.
    • (2013) Inhal. Toxicol. , vol.25 , pp. 134-140
    • Carson, J.L.1    Brighton, L.E.2    Collier, A.M.3    Bromberg, P.A.4
  • 32
    • 84863446688 scopus 로고    scopus 로고
    • Ultrastructural pathology of endothelial tight junctions in human brain edema
    • Castejón O.J. Ultrastructural pathology of endothelial tight junctions in human brain edema. Folia Neuropathol. 2012, 50:118-129.
    • (2012) Folia Neuropathol. , vol.50 , pp. 118-129
    • Castejón, O.J.1
  • 33
    • 84899572672 scopus 로고    scopus 로고
    • Ultrastructural alterations of human cortical capillary basement membrane in human brain oedema
    • Castejón O.J. Ultrastructural alterations of human cortical capillary basement membrane in human brain oedema. Folia Neuropathol. 2014, 52:10-21.
    • (2014) Folia Neuropathol. , vol.52 , pp. 10-21
    • Castejón, O.J.1
  • 35
    • 84936767918 scopus 로고    scopus 로고
    • Unraveling the potential co-contributors of cerebral small vessel vasculopathy to the pathogenesis of Alzheimer's dementia
    • Edwards J.D., Ramírez J., Black S.E. Unraveling the potential co-contributors of cerebral small vessel vasculopathy to the pathogenesis of Alzheimer's dementia. Alzheimers Res. Ther. 2015, 7(1):49. 10.1186/s13195-015-0133-2.
    • (2015) Alzheimers Res. Ther. , vol.7 , Issue.1 , pp. 49
    • Edwards, J.D.1    Ramírez, J.2    Black, S.E.3
  • 36
    • 84921044808 scopus 로고    scopus 로고
    • Vasospasm in cerebral inflammation
    • Eisenhut M. Vasospasm in cerebral inflammation. Int. J. Inflamm. 2014, 2014:509707. 10.1155/2014/509707.
    • (2014) Int. J. Inflamm. , vol.2014
    • Eisenhut, M.1
  • 37
    • 84928748740 scopus 로고    scopus 로고
    • Blood-brain-barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment
    • Elahy M., Jackaman C., Mamo J.C., Lam V., Dhaliwal S.S., Giles C., Nelson D., Takechi R. Blood-brain-barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment. Immun. Ageing 2015, 12:2. 10.1186/s12979-015-0029-9.
    • (2015) Immun. Ageing , vol.12 , pp. 2
    • Elahy, M.1    Jackaman, C.2    Mamo, J.C.3    Lam, V.4    Dhaliwal, S.S.5    Giles, C.6    Nelson, D.7    Takechi, R.8
  • 38
    • 84975807860 scopus 로고    scopus 로고
    • Air pollution-induced vascular dysfunction: potential role of endothelin-1 (ET-1) system
    • Finch J., Conklin D.J. Air pollution-induced vascular dysfunction: potential role of endothelin-1 (ET-1) system. Cardiovasc. Toxicol. 2015.
    • (2015) Cardiovasc. Toxicol.
    • Finch, J.1    Conklin, D.J.2
  • 39
    • 84937945046 scopus 로고    scopus 로고
    • Alzheimer's disease neuroimaging initiative. Altered whole-brain white matter networks in preclinical Alzheimer's disease
    • Fischer F.U., Wolf D., Scheurich A., Fellgiebel A. Alzheimer's disease neuroimaging initiative. Altered whole-brain white matter networks in preclinical Alzheimer's disease. Neuroimage Clin. 2015, 8:660-666. 10.1016/j.nicl.2015.06.007.
    • (2015) Neuroimage Clin. , vol.8 , pp. 660-666
    • Fischer, F.U.1    Wolf, D.2    Scheurich, A.3    Fellgiebel, A.4
  • 40
    • 84911062720 scopus 로고    scopus 로고
    • MRC cognitive function and ageing Study. DNA damage response and senescence in endothelial cells of human cerebral cortex and relation to Alzheimer's neuropathology progression: a population-based study in the Medical Research Council Cognitive Function and Ageing Study (MRC-CFAS) cohort
    • Garwood C.J., Simpson J.E., Al Mashhadi S., Axe C., Wilson S., Heath P.R., Shaw P.J., Matthews F.E., Brayne C., Ince P.G., Wharton S.B. MRC cognitive function and ageing Study. DNA damage response and senescence in endothelial cells of human cerebral cortex and relation to Alzheimer's neuropathology progression: a population-based study in the Medical Research Council Cognitive Function and Ageing Study (MRC-CFAS) cohort. Neuropathol. Appl. Neurobiol. 2014, 40:802-814.
    • (2014) Neuropathol. Appl. Neurobiol. , vol.40 , pp. 802-814
    • Garwood, C.J.1    Simpson, J.E.2    Al Mashhadi, S.3    Axe, C.4    Wilson, S.5    Heath, P.R.6    Shaw, P.J.7    Matthews, F.E.8    Brayne, C.9    Ince, P.G.10    Wharton, S.B.11
  • 44
    • 33646777094 scopus 로고    scopus 로고
    • The nose revisited: a brief review of the comparative structure, function, and toxicologic pathology of the nasal epithelium
    • Harkema J.R., Carey S.A., Wagner J.G. The nose revisited: a brief review of the comparative structure, function, and toxicologic pathology of the nasal epithelium. Toxicol. Pathol. 2006, 34:252-269.
    • (2006) Toxicol. Pathol. , vol.34 , pp. 252-269
    • Harkema, J.R.1    Carey, S.A.2    Wagner, J.G.3
  • 45
    • 84928204290 scopus 로고    scopus 로고
    • Transmembrane proteins of the tight junctions at the blood-brain barrier: structural and functional aspects
    • Haseloff R.F., Dithmer S., Winkler L., Wolburg H., Blasig I.E. Transmembrane proteins of the tight junctions at the blood-brain barrier: structural and functional aspects. Semin. Cell Dev. Biol. 2015, 38:16-25. 10.1016/j.semcdb.2014.11.004.
    • (2015) Semin. Cell Dev. Biol. , vol.38 , pp. 16-25
    • Haseloff, R.F.1    Dithmer, S.2    Winkler, L.3    Wolburg, H.4    Blasig, I.E.5
  • 46
    • 84922754904 scopus 로고    scopus 로고
    • Prenatal high-fat diet alters the cerebrovasculature and clearance of β-amyloid in adult offspring
    • Hawkes C.A., Gentleman S.M., Nicoll J.A., Carare R.O. Prenatal high-fat diet alters the cerebrovasculature and clearance of β-amyloid in adult offspring. J. Pathol. 2015, 235:619-631.
    • (2015) J. Pathol. , vol.235 , pp. 619-631
    • Hawkes, C.A.1    Gentleman, S.M.2    Nicoll, J.A.3    Carare, R.O.4
  • 47
    • 84902687106 scopus 로고    scopus 로고
    • Failure of perivascular drainage of β-amyloid in cerebral amyloid angiopathy
    • Hawkes C.A., Jayakody N., Johnston D.A., Bechmann I., Carare R.O. Failure of perivascular drainage of β-amyloid in cerebral amyloid angiopathy. Brain Pathol. 2014, 24:396-403.
    • (2014) Brain Pathol. , vol.24 , pp. 396-403
    • Hawkes, C.A.1    Jayakody, N.2    Johnston, D.A.3    Bechmann, I.4    Carare, R.O.5
  • 48
    • 84942983582 scopus 로고    scopus 로고
    • Selective astrocytic endothelin-1 overexpression contributes to dementia associated with ischemic stroke by exaggerating astrocyte-derived amyloid secretion
    • Hung V.K., Yeung P.K., Lai A.K., Ho M.C., Chan K.C., Wu E.X., Chung S.S., Cheung C.W., Chung S.K. Selective astrocytic endothelin-1 overexpression contributes to dementia associated with ischemic stroke by exaggerating astrocyte-derived amyloid secretion. J. Cereb. Blood Flow. Metab. 2015, 35:1687-1696. 10.1038/jcbfm.2015.109.
    • (2015) J. Cereb. Blood Flow. Metab. , vol.35 , pp. 1687-1696
    • Hung, V.K.1    Yeung, P.K.2    Lai, A.K.3    Ho, M.C.4    Chan, K.C.5    Wu, E.X.6    Chung, S.S.7    Cheung, C.W.8    Chung, S.K.9
  • 49
    • 2342614850 scopus 로고    scopus 로고
    • Neurovascular regulation in the normal brain and in Alzheimer's disease
    • Iadecola C. Neurovascular regulation in the normal brain and in Alzheimer's disease. Nat. Rev. Neurosci. 2004, 5:347-360.
    • (2004) Nat. Rev. Neurosci. , vol.5 , pp. 347-360
    • Iadecola, C.1
  • 50
    • 84921529718 scopus 로고    scopus 로고
    • Ozone particulate matter and newly diagnosed Alzheimer's disease: a population-based cohort study in Taiwan
    • Jung C.R., Lin Y.T., Hwang B.F. Ozone particulate matter and newly diagnosed Alzheimer's disease: a population-based cohort study in Taiwan. J. Alzheimers Dis. 2015, 44:573-584.
    • (2015) J. Alzheimers Dis. , vol.44 , pp. 573-584
    • Jung, C.R.1    Lin, Y.T.2    Hwang, B.F.3
  • 51
    • 84946874086 scopus 로고    scopus 로고
    • Astrocyte mediated MMP-9 activation in the synapse dysfunction: an implication in Alzheimer disease
    • pii
    • Kamat P.K., Swarnkar S., Rai S., Kumar V., Tyagi N. Astrocyte mediated MMP-9 activation in the synapse dysfunction: an implication in Alzheimer disease. Ther. Targets Neurol. Dis. 2014, 1(1):e243. pii.
    • (2014) Ther. Targets Neurol. Dis. , vol.1 , Issue.1
    • Kamat, P.K.1    Swarnkar, S.2    Rai, S.3    Kumar, V.4    Tyagi, N.5
  • 54
    • 84886652572 scopus 로고    scopus 로고
    • Nitrogen dioxide and ultrafine particles dominate the biological effects of inhaled diesel exhaust treated by a catalyzed diesel particulate filter
    • Karthikeyan S., Thomson E.M., Kumarathasan P., Guénette J., Rosenblatt D., Chan T., Rideout G., Vincent R. Nitrogen dioxide and ultrafine particles dominate the biological effects of inhaled diesel exhaust treated by a catalyzed diesel particulate filter. Toxicol. Sci. 2013, 135:437-450.
    • (2013) Toxicol. Sci. , vol.135 , pp. 437-450
    • Karthikeyan, S.1    Thomson, E.M.2    Kumarathasan, P.3    Guénette, J.4    Rosenblatt, D.5    Chan, T.6    Rideout, G.7    Vincent, R.8
  • 55
    • 84945457224 scopus 로고    scopus 로고
    • The dynamic blood-brain-barrier
    • Aug 16
    • Keaney J., Campbell M. The dynamic blood-brain-barrier. FEBS J. 2015, 282:4067-4079. Aug 16. 10.1111/febs.13412.
    • (2015) FEBS J. , vol.282 , pp. 4067-4079
    • Keaney, J.1    Campbell, M.2
  • 56
    • 84983096050 scopus 로고    scopus 로고
    • Control of cerebrovascular patterning by neural activity during postnatal development
    • Lacoste B., Gu C. Control of cerebrovascular patterning by neural activity during postnatal development. Mech. Dev. 2015, 138:43-49. 10.1016/j.mod.2015.06.003.
    • (2015) Mech. Dev. , vol.138 , pp. 43-49
    • Lacoste, B.1    Gu, C.2
  • 57
    • 84928821923 scopus 로고    scopus 로고
    • Venular degeneration leads to vascular dysfunction in a transgenic model of Alzheimer's disease
    • Lai A.Y., Dorr A., Thomason L.A., Koletar M.M., Sled J.G., Stefanovic B., Mclaurin J. Venular degeneration leads to vascular dysfunction in a transgenic model of Alzheimer's disease. Brain 2015, 138(Pt 4):1046-1058. 10.1093/brain/awv023.
    • (2015) Brain , vol.138 , pp. 1046-1058
    • Lai, A.Y.1    Dorr, A.2    Thomason, L.A.3    Koletar, M.M.4    Sled, J.G.5    Stefanovic, B.6    Mclaurin, J.7
  • 58
    • 84882273124 scopus 로고    scopus 로고
    • Drainage of cells and soluble antigen from the CNS to regional lymph nodes
    • Laman J.D., Weller R.O. Drainage of cells and soluble antigen from the CNS to regional lymph nodes. J. Neuroimmune Pharmacol. 2013, 8:840-856.
    • (2013) J. Neuroimmune Pharmacol. , vol.8 , pp. 840-856
    • Laman, J.D.1    Weller, R.O.2
  • 59
    • 80051666509 scopus 로고    scopus 로고
    • The neurovascular unit in brain function and disease
    • Lecrux C., Hamel E. The neurovascular unit in brain function and disease. Acta Physiol. 2011, 203:47-59.
    • (2011) Acta Physiol. , vol.203 , pp. 47-59
    • Lecrux, C.1    Hamel, E.2
  • 60
    • 84921938755 scopus 로고    scopus 로고
    • Endothelin-1 expression and alterations of cerebral microcirculation after experimental subarachnoid hemmorrhage
    • Lei Q., Li S., Zheng R., Xu K., Li S. Endothelin-1 expression and alterations of cerebral microcirculation after experimental subarachnoid hemmorrhage. Neuroradiology 2015, 57:63-70.
    • (2015) Neuroradiology , vol.57 , pp. 63-70
    • Lei, Q.1    Li, S.2    Zheng, R.3    Xu, K.4    Li, S.5
  • 61
    • 77955509822 scopus 로고    scopus 로고
    • Brain-reactive autoantibodies are nearly ubiquitous in human sera and may be linked to pathology in the context of blood-brain barrier breakdown
    • Levin E.C., Acharya N.K., Han M., Zavareh S.B., Sedeyn J.C., Venkataraman V., Nagele R.G. Brain-reactive autoantibodies are nearly ubiquitous in human sera and may be linked to pathology in the context of blood-brain barrier breakdown. Brain Res. 2010, 1345:221-232.
    • (2010) Brain Res. , vol.1345 , pp. 221-232
    • Levin, E.C.1    Acharya, N.K.2    Han, M.3    Zavareh, S.B.4    Sedeyn, J.C.5    Venkataraman, V.6    Nagele, R.G.7
  • 62
    • 84947779009 scopus 로고    scopus 로고
    • Gold nanoparticles increase endothelial paracellular permeability by altering components of endothelial tight junctions, and increase blood-brain barrier permeability in mice
    • Aug 13. pii: kfv176
    • Li C.H., Jhan C., Cheng Y.W., Tsai C.H., Liu C.W., Lee C.C., Chen R.M., Shyu M.K., Kang J.J. Gold nanoparticles increase endothelial paracellular permeability by altering components of endothelial tight junctions, and increase blood-brain barrier permeability in mice. Toxicol. Sci. 2015, 148:192-203. Aug 13. pii: kfv176.
    • (2015) Toxicol. Sci. , vol.148 , pp. 192-203
    • Li, C.H.1    Jhan, C.2    Cheng, Y.W.3    Tsai, C.H.4    Liu, C.W.5    Lee, C.C.6    Chen, R.M.7    Shyu, M.K.8    Kang, J.J.9
  • 63
    • 84983095294 scopus 로고    scopus 로고
    • The vascular niche in adult neurogenesis
    • pii: S0925-4773(15)00045-3
    • Licht T., Keshet E. The vascular niche in adult neurogenesis. Mech. Dev. 2015, 138:56-62. pii: S0925-4773(15)00045-3. 10.1016/j.mod.2015.06.001.
    • (2015) Mech. Dev. , vol.138 , pp. 56-62
    • Licht, T.1    Keshet, E.2
  • 65
    • 62949092903 scopus 로고    scopus 로고
    • The neurovascular unit in health and disease
    • Lo E.H., Rosenberg G.A. The neurovascular unit in health and disease. Stroke 2009, 40:S2-S3.
    • (2009) Stroke , vol.40 , pp. S2-S3
    • Lo, E.H.1    Rosenberg, G.A.2
  • 66
    • 84931266835 scopus 로고    scopus 로고
    • Neurovascular and neurometabolic derailment in aging and Alzheimer's disease
    • Lourenco C.F., Ledo A., Dias C., Barbosa R.M., Laranjinha J. Neurovascular and neurometabolic derailment in aging and Alzheimer's disease. Front. Aging Neurosci. 2015, 7:103. 10.3389/fnagi.2015.00103.
    • (2015) Front. Aging Neurosci. , vol.7 , pp. 103
    • Lourenco, C.F.1    Ledo, A.2    Dias, C.3    Barbosa, R.M.4    Laranjinha, J.5
  • 67
    • 84923359693 scopus 로고    scopus 로고
    • White matter hypoperfusion and damage in dementia: post-mortem assessment
    • Love S., Miners J.S. White matter hypoperfusion and damage in dementia: post-mortem assessment. Brain Pathol. 2015, 25:99-107.
    • (2015) Brain Pathol. , vol.25 , pp. 99-107
    • Love, S.1    Miners, J.S.2
  • 68
    • 84871726572 scopus 로고    scopus 로고
    • Polycyclic aromatic hydrocarbons in the urban atmosphere of Mexico City
    • InTech, Croatia, V. Villanyi (Ed.)
    • Mugica V., Torres M., Salinas E., Gutiérrez M., García R. Polycyclic aromatic hydrocarbons in the urban atmosphere of Mexico City. Air Pollution 2010, 73-97. InTech, Croatia. http://www.intechopen.com/books/air-pollution/polycyclic-aromatichydrocarbons-in-the-urban-atmosphere-of-mexico-city, V. Villanyi (Ed.).
    • (2010) Air Pollution , pp. 73-97
    • Mugica, V.1    Torres, M.2    Salinas, E.3    Gutiérrez, M.4    García, R.5
  • 70
    • 77954394706 scopus 로고    scopus 로고
    • The perivascular astroglial sheath provides a complete covering of the brain microvessels: an electron microscopic 3D reconstruction
    • Mathiisen T.M., Lehre K.P., Danbolt N.C., Ottersen O.P. The perivascular astroglial sheath provides a complete covering of the brain microvessels: an electron microscopic 3D reconstruction. Glia 2010, 58:1094-1103. 10.1002/glia.20990.
    • (2010) Glia , vol.58 , pp. 1094-1103
    • Mathiisen, T.M.1    Lehre, K.P.2    Danbolt, N.C.3    Ottersen, O.P.4
  • 71
    • 84924968824 scopus 로고    scopus 로고
    • Nano-Mg(OH)2-induced proliferation inhibition and dysfunction of human umbilical vein vascular endothelial cells through caveolin-1-mediated endocytosis
    • Meng N., Han L., Pan X., Su L., Jiang Z., Lin Z., Zhao J., Zhang S., Zhang Y., Zhao B., Miao J. Nano-Mg(OH)2-induced proliferation inhibition and dysfunction of human umbilical vein vascular endothelial cells through caveolin-1-mediated endocytosis. Cell Biol. Toxicol. 2015, 31:15-27.
    • (2015) Cell Biol. Toxicol. , vol.31 , pp. 15-27
    • Meng, N.1    Han, L.2    Pan, X.3    Su, L.4    Jiang, Z.5    Lin, Z.6    Zhao, J.7    Zhang, S.8    Zhang, Y.9    Zhao, B.10    Miao, J.11
  • 73
    • 84907222721 scopus 로고    scopus 로고
    • The cerebrovascular basement membrane: role in the clearance of β-amyloid and cerebral amyloid angiopathy
    • Morris A.W., Carare R.O., Schreiber S., Hawkes C.A. The cerebrovascular basement membrane: role in the clearance of β-amyloid and cerebral amyloid angiopathy. Front. Aging Neurosci. 2014, 19:251. 10.3389/fnagi.2014.00251.
    • (2014) Front. Aging Neurosci. , vol.19 , pp. 251
    • Morris, A.W.1    Carare, R.O.2    Schreiber, S.3    Hawkes, C.A.4
  • 74
    • 27844597210 scopus 로고
    • Quintuple-layered membrane junctions at terminal bars between endothelial cells
    • Muir A.R., Peter A. Quintuple-layered membrane junctions at terminal bars between endothelial cells. J. Cell Biol. 1962, 12:443-448.
    • (1962) J. Cell Biol. , vol.12 , pp. 443-448
    • Muir, A.R.1    Peter, A.2
  • 75
    • 84925945426 scopus 로고    scopus 로고
    • Systemic inflammation impairs tissue reperfusion through endothelin-dependent mechanisms in cerebral ischemia
    • Murray K.N., Girard S., Holmes W.M., Parkes L.M., Williams S.R., Parry-Jones A.R., Allan S.M. Systemic inflammation impairs tissue reperfusion through endothelin-dependent mechanisms in cerebral ischemia. Stroke 2014, 45:3412-3419.
    • (2014) Stroke , vol.45 , pp. 3412-3419
    • Murray, K.N.1    Girard, S.2    Holmes, W.M.3    Parkes, L.M.4    Williams, S.R.5    Parry-Jones, A.R.6    Allan, S.M.7
  • 77
    • 84883878305 scopus 로고    scopus 로고
    • Alzheimer's Disease Neuroimaging Initiative (ADNI). Effectiveness of regional DTI measures in distinguishing Alzheimer's disease, MCI and normal aging
    • Nir T.M., Jahanshad N., Villalon-Reina J.E., Toga A.W., Jack C.R., Weiner M.W., Thompson P.M. Alzheimer's Disease Neuroimaging Initiative (ADNI). Effectiveness of regional DTI measures in distinguishing Alzheimer's disease, MCI and normal aging. Neuroimage Clin. 2013, 180-195.
    • (2013) Neuroimage Clin. , pp. 180-195
    • Nir, T.M.1    Jahanshad, N.2    Villalon-Reina, J.E.3    Toga, A.W.4    Jack, C.R.5    Weiner, M.W.6    Thompson, P.M.7
  • 78
    • 84924650926 scopus 로고    scopus 로고
    • White matter hyperintensities, cognitive impairment and dementia: an update
    • Prins N.D., Scheltens P. White matter hyperintensities, cognitive impairment and dementia: an update. Nat. Rev. Neurol. 2015, 11:157-165.
    • (2015) Nat. Rev. Neurol. , vol.11 , pp. 157-165
    • Prins, N.D.1    Scheltens, P.2
  • 80
    • 84952639354 scopus 로고    scopus 로고
    • Regulation of ABC efflux transporters at blood-brain barrier in health and neurological disorders
    • Jul 15. pii: S0006-8993(15)00530-2
    • Qosa H., Miller D.S., Pasinelli P., Trotti D. Regulation of ABC efflux transporters at blood-brain barrier in health and neurological disorders. Brain Res. 2015, 1628:298-316. Jul 15. pii: S0006-8993(15)00530-2.
    • (2015) Brain Res. , vol.1628 , pp. 298-316
    • Qosa, H.1    Miller, D.S.2    Pasinelli, P.3    Trotti, D.4
  • 82
    • 84940661645 scopus 로고    scopus 로고
    • Seasonal and diurnal trends in black carbon properties and co-pollutants in Mexico City
    • Retama A., Baumgardner D., Raga G.B., McMeeking G.R., Walker J.W. Seasonal and diurnal trends in black carbon properties and co-pollutants in Mexico City. Atmos. Chem. Phys. 2015, 15:9693-9709.
    • (2015) Atmos. Chem. Phys. , vol.15 , pp. 9693-9709
    • Retama, A.1    Baumgardner, D.2    Raga, G.B.3    McMeeking, G.R.4    Walker, J.W.5
  • 85
    • 84885233952 scopus 로고    scopus 로고
    • Size and age-dependent neurotoxicity of engineered metal nanoparticles in rats
    • Sharma A., Muresanu D.F., Patnaik R., Sharma H.S. Size and age-dependent neurotoxicity of engineered metal nanoparticles in rats. Mol. Neurobiol. 2013, 48:386-396.
    • (2013) Mol. Neurobiol. , vol.48 , pp. 386-396
    • Sharma, A.1    Muresanu, D.F.2    Patnaik, R.3    Sharma, H.S.4
  • 88
    • 84934444613 scopus 로고    scopus 로고
    • Cerebrospinal fluid biomarkers of neurovascular dysfunction in mild dementia and Alzheimer's disease
    • Sweeney M.D., Sagare A.P., Zlokovic B.V. Cerebrospinal fluid biomarkers of neurovascular dysfunction in mild dementia and Alzheimer's disease. J. Cereb. Blood Flow Metab. 2015, 35:1055-1068.
    • (2015) J. Cereb. Blood Flow Metab. , vol.35 , pp. 1055-1068
    • Sweeney, M.D.1    Sagare, A.P.2    Zlokovic, B.V.3
  • 90
    • 27644444787 scopus 로고    scopus 로고
    • Differential regulation of the lung endothelin system by urban particulate matter and ozone
    • Thomson E.M., Kumarathasan P., Goegan P., Aubin R.A., Vincent R. Differential regulation of the lung endothelin system by urban particulate matter and ozone. Toxicol. Sci. 2005, 88:103-113.
    • (2005) Toxicol. Sci. , vol.88 , pp. 103-113
    • Thomson, E.M.1    Kumarathasan, P.2    Goegan, P.3    Aubin, R.A.4    Vincent, R.5
  • 91
    • 84943255434 scopus 로고    scopus 로고
    • Brain barriers: Crosstalk between complex tight junctions and adherens junctions
    • Tietz S., Engelhardt B. Brain barriers: Crosstalk between complex tight junctions and adherens junctions. J. Cell Biol. 2015, 209:493-506. 10.1083/jcb.201412147.
    • (2015) J. Cell Biol. , vol.209 , pp. 493-506
    • Tietz, S.1    Engelhardt, B.2
  • 92
    • 84890412257 scopus 로고    scopus 로고
    • In vitro toxicological screening of nanoparticles on primary human endothelial cells and the role of flow in modulating cell response
    • Ucciferri N., Collnot E.M., Gaiser B.K., Tirella A., Stone V., Domenici C., Lehr C.M., Ahluwalia A. In vitro toxicological screening of nanoparticles on primary human endothelial cells and the role of flow in modulating cell response. Nanotoxicology 2014, 8:697-708.
    • (2014) Nanotoxicology , vol.8 , pp. 697-708
    • Ucciferri, N.1    Collnot, E.M.2    Gaiser, B.K.3    Tirella, A.4    Stone, V.5    Domenici, C.6    Lehr, C.M.7    Ahluwalia, A.8
  • 93
    • 25144507762 scopus 로고    scopus 로고
    • CC16 as a marker of lung epithelial hyperpermeability in an acute model of rats exposed to mainstream cigarette smoke
    • Van Miert E., Dumont X., Bernard A. CC16 as a marker of lung epithelial hyperpermeability in an acute model of rats exposed to mainstream cigarette smoke. Toxicol. Lett. 2005, 159:115-123.
    • (2005) Toxicol. Lett. , vol.159 , pp. 115-123
    • Van Miert, E.1    Dumont, X.2    Bernard, A.3
  • 95
    • 0036771111 scopus 로고    scopus 로고
    • Assessment of physical education time and after-school outdoor time in elementary and middle school students in south Mexico City: the dilemma between physical fitness and the adverse health effects of outdoor pollutant exposure
    • Villarreal-Calderón A., Acuña H., Villarreal-Calderón J., Garduño M., Henríquez-Roldán C.F., Calderón-Garcidueñas L., Valencia-Salazar G. Assessment of physical education time and after-school outdoor time in elementary and middle school students in south Mexico City: the dilemma between physical fitness and the adverse health effects of outdoor pollutant exposure. Arch. Environ. Health 2002, 57:450-460.
    • (2002) Arch. Environ. Health , vol.57 , pp. 450-460
    • Villarreal-Calderón, A.1    Acuña, H.2    Villarreal-Calderón, J.3    Garduño, M.4    Henríquez-Roldán, C.F.5    Calderón-Garcidueñas, L.6    Valencia-Salazar, G.7
  • 97
    • 73849141603 scopus 로고    scopus 로고
    • Size and dynamics of caveolae studied using nanoparticles in living endothelial cells
    • Wang Z., Tiruppathi C., Minshall R.D., Malik A.B. Size and dynamics of caveolae studied using nanoparticles in living endothelial cells. ACS Nano 2009, 3:4110-4116.
    • (2009) ACS Nano , vol.3 , pp. 4110-4116
    • Wang, Z.1    Tiruppathi, C.2    Minshall, R.D.3    Malik, A.B.4
  • 100
    • 67349118757 scopus 로고    scopus 로고
    • Microvasculature changes and cerebral amyloid angiopathy in Alzheimer's disease and their potential impact on therapy
    • Weller R.O., Boche D., Nicoll J.A. Microvasculature changes and cerebral amyloid angiopathy in Alzheimer's disease and their potential impact on therapy. Acta Neuropathol. 2009, 118:87-102.
    • (2009) Acta Neuropathol. , vol.118 , pp. 87-102
    • Weller, R.O.1    Boche, D.2    Nicoll, J.A.3
  • 101
    • 84923327428 scopus 로고    scopus 로고
    • White matter changes in dementia: role of impaired drainage of interstitial fluid
    • Weller R.O., Hawkes C.A., Kalaria R.N., Werring D.J., Carare R.O. White matter changes in dementia: role of impaired drainage of interstitial fluid. Brain Pathol. 2015, 25:63-78.
    • (2015) Brain Pathol. , vol.25 , pp. 63-78
    • Weller, R.O.1    Hawkes, C.A.2    Kalaria, R.N.3    Werring, D.J.4    Carare, R.O.5
  • 102
    • 84902652960 scopus 로고    scopus 로고
    • The pericyte: a forgotten cell type with important implications for Alzheimer's disease?
    • Winkler E.A., Sagare A.P., Zlokovic B.V. The pericyte: a forgotten cell type with important implications for Alzheimer's disease?. Brain Pathol. 2014, 24:371-386. 10.1111/bpa.12152.
    • (2014) Brain Pathol. , vol.24 , pp. 371-386
    • Winkler, E.A.1    Sagare, A.P.2    Zlokovic, B.V.3
  • 103
    • 0033900999 scopus 로고    scopus 로고
    • Chronic overproduction of Transforming growth factor β-1 by astrocytes promotes Alzheimer's disease-like microvascular degeneration in transgenic mice
    • Wyss-Coray T., Lin C., Sanan D.A., Mucke L., Masliah E. Chronic overproduction of Transforming growth factor β-1 by astrocytes promotes Alzheimer's disease-like microvascular degeneration in transgenic mice. Am. J. Pathol. 2000, 156:139-150.
    • (2000) Am. J. Pathol. , vol.156 , pp. 139-150
    • Wyss-Coray, T.1    Lin, C.2    Sanan, D.A.3    Mucke, L.4    Masliah, E.5
  • 104
    • 84878340773 scopus 로고    scopus 로고
    • Nanoparticle-induced tight-junction opening for the transport of an anti-angiogenic sulfated polysaccharide across Caco-2 cell monolayers
    • Yu S.H., Tang D.W., Hsieh H.Y., Wu W.S., Lin B.X., Chuang E.Y., Sung H.W., Mi F.L. Nanoparticle-induced tight-junction opening for the transport of an anti-angiogenic sulfated polysaccharide across Caco-2 cell monolayers. Acta Biomater. 2013, 9:7449-7459.
    • (2013) Acta Biomater. , vol.9 , pp. 7449-7459
    • Yu, S.H.1    Tang, D.W.2    Hsieh, H.Y.3    Wu, W.S.4    Lin, B.X.5    Chuang, E.Y.6    Sung, H.W.7    Mi, F.L.8
  • 105
    • 38149090292 scopus 로고    scopus 로고
    • The blood-brain-barrier in health and chronic neurodegenerative disorders
    • Zlokovic B.V. The blood-brain-barrier in health and chronic neurodegenerative disorders. Neuron 2008, 57:178-201.
    • (2008) Neuron , vol.57 , pp. 178-201
    • Zlokovic, B.V.1


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