Effects of a Cyclooxygenase-2 Preferential Inhibitor in Young Healthy Dogs Exposed to Air Pollution: A Pilot Study

Toxicologic Pathology

Volumn 37, Issue 5, 2009, Pages 644-660

  Calderón Garcidueñas, Lilian ^a,b   Mora Tiscareño, Antonieta ^a   Gómez Garza, Gilberto ^a   Carrasco Portugal, Miriam Del C ^c   Pérez Guillé, Beatriz ^a   Flores Murrieta, Francisco J ^d   Pérez Guillé, Gabriela ^a   Osnaya, Norma ^a   Juárez Olguín, Hugo ^a   Monroy, Maria E ^a   Monroy, Silvia ^a   González Maciel, Angelica ^a   Reynoso Robles, Rafael ^a   Villarreal Calderon, Rafael ^b   Patel, Sarjubhai A ^b   Kumarathasan, Prem ^e   Vincent, Renaud ^e   Henríquez Roldán, Carlos ^f   Torres Jardón, Ricardo ^g   Maronpot, Robert R ^h  

^a INSTITUTO NACIONAL DE PEDIATRÍA   (Mexico)

^b UNIVERSITY OF MONTANA   (United States)

^c INSTITUTO NACIONAL DE ENFERMEDADES RESPIRATORIAS   (Mexico)

^d INSTITUTO POLITÉCNICO NACIONAL   (Mexico)

^e Environmental Health Center   (Canada)

^f Licenciada en Ciencias Jurídicas y Sociales   (United States)

^g UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^h EXPERIMENTAL PATHOLOGY LABORATORIES INC   (United States)

Author keywords

air pollution; Alzheimer s disease; brain MRI; cerebrospinal fluid; dogs; neuroinflammation; neuroprotection; Nimesulide

Indexed keywords

3 NITROTYROSINE; AMYLOID BETA PROTEIN[1-40]; AQUAPORIN 4; CD14 ANTIGEN; INTERLEUKIN 1BETA; MESSENGER RNA; NIMESULIDE; PROSTAGLANDIN E2; AMYLOID BETA PROTEIN; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; OZONE; PROSTAGLANDIN E; SULFONAMIDE; TYROSINE;

AIR POLLUTION; AIR QUALITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CEREBROSPINAL FLUID LEVEL; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DOG; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG HALF LIFE; DRUG INHIBITION; ENZYME BLOOD LEVEL; MAXIMUM PLASMA CONCENTRATION; NEUROPATHOLOGY; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PILOT STUDY; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RNA ANALYSIS; ANIMAL; BRAIN; CHI SQUARE DISTRIBUTION; FRONTAL LOBE; GENETICS; HISTOLOGY; IMMUNOHISTOCHEMISTRY; METABOLISM; MEXICO; NONPARAMETRIC TEST; NOSE MUCOSA; PATHOLOGY;

CANIS FAMILIARIS;

AIR POLLUTION; AMYLOID BETA-PROTEIN; ANIMALS; ANTIGENS, CD14; AQUAPORIN 4; BRAIN; CHI-SQUARE DISTRIBUTION; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DOGS; FRONTAL LOBE; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1BETA; MAGNETIC RESONANCE IMAGING; MEXICO; NASAL MUCOSA; OZONE; PILOT PROJECTS; PROSTAGLANDINS E; STATISTICS, NONPARAMETRIC; SULFONAMIDES; TYROSINE;

EID: 70350450330     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1177/0192623309340277     Document Type: Article

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