Systemic inflammation impairs tissue reperfusion through endothelin-dependent mechanisms in cerebral ischemia

Stroke

Volumn 45, Issue 11, 2014, Pages 3412-3419

  Murray, Katie N ^a   Girard, Sylvie ^b   Holmes, William M ^c   Parkes, Laura M ^a   Williams, Stephen R ^a   Parry Jones, Adrian R ^a   Allan, Stuart M ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF MONTREAL   (Canada)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Brain ischemia; Endothelin 1; Inflammation; Interleukin 1; Magnetic resonance imaging; Reperfusion

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN; ENDOTHELIN 1; INTERLEUKIN 1; INTERLEUKIN 1BETA; RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD FLOW; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; DIFFUSION WEIGHTED IMAGING; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTOPATHOLOGY; IMAGE ANALYSIS; IMMUNOFLUORESCENCE; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PERFUSION; PERFUSION WEIGHTED IMAGING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; RNA EXTRACTION; THROMBOCYTE AGGREGATION; THROMBOCYTE COUNT; TISSUE INJURY; TISSUE PERFUSION; UPREGULATION; ANIMAL; BIOSYNTHESIS; BRAIN CIRCULATION; CHEMICALLY INDUCED; DRUG EFFECTS; METABOLISM; PATHOLOGY; PHYSIOLOGY; RANDOMIZATION; WISTAR RAT;

ANIMALS; BRAIN ISCHEMIA; CEREBROVASCULAR CIRCULATION; ENDOTHELINS; INFLAMMATION; INTERLEUKIN-1BETA; MALE; RANDOM ALLOCATION; RATS; RATS, WISTAR;

EID: 84925945426     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.114.006613     Document Type: Article

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