A critical proton MR spectroscopy marker of Alzheimer's disease early neurodegenerative change: Low hippocampal NAA/Cr ratio impacts APOE ε 4 Mexico City children and their parents

Journal of Alzheimer's Disease

Volumn 48, Issue 4, 2015, Pages 1065-1075

  Calderón Garcidueñas, Lilian ^a,b   Mora Tiscareño, Antonieta ^c   Melo Sánchez, Gastón ^b   Rodríguez Díaz, Joel ^d   Torres Jardón, Ricardo ^e   Styner, Martin ^f   Mukherjee, Partha S ^g   Lin, Weili ^f   Jewells, Valerie ^f  

^a UNIVERSITY OF MONTANA   (United States)

^b UNIVERSIDAD DEL VALLE DE MÉXICO   (Mexico)

^c INSTITUTO NACIONAL DE PEDIATRÍA   (Mexico)

^d Centro Médico Cozumel   (Mexico)

^e UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^f UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^g BOISE STATE UNIVERSITY   (United States)

Author keywords

Air Pollution; APOE; body mass index; children; hippocampus; magnetic resonance spectroscopy; memory; NAA Cr ratio; neuroprotection; PM2.5

Indexed keywords

APOLIPOPROTEIN E4; BIOLOGICAL MARKER; CHOLINE; CREATINE; INOSITOL; N ACETYLASPARTIC ACID; OZONE; ASPARTIC ACID; MAPT PROTEIN, HUMAN; N-ACETYLASPARTATE; TAU PROTEIN;

ADULT; AIR POLLUTION; ALLELE; ALZHEIMER DISEASE; ANALYTICAL PARAMETERS; ARTICLE; BODY MASS; CHILD; CHOLINE TO CREATINE RATIO; COGNITION; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; ENVIRONMENTAL FACTOR; FEMALE; HEREDITY; HIGH RISK POPULATION; HIPPOCAMPUS; HUMAN; LONG TERM EXPOSURE; MAJOR CLINICAL STUDY; MALE; MEXICO; MYO INOSITOL TO CREATINE RATIO; N ACETYL ASPATIC ACID TO CREATINE RATIO; NERVE DEGENERATION; NEUROPROTECTION; NUCLEAR MAGNETIC RESONANCE SCANNER; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PARTICULATE MATTER; PRIORITY JOURNAL; SYMPTOMATOLOGY; SYNAPSE; URBAN POPULATION; ADOLESCENT; ADVERSE EFFECTS; ANALOGS AND DERIVATIVES; FAMILY; GENETICS; METABOLISM; PROSPECTIVE STUDY; PROTON NUCLEAR MAGNETIC RESONANCE;

ADOLESCENT; ADULT; AIR POLLUTION; ALZHEIMER DISEASE; APOLIPOPROTEIN E4; ASPARTIC ACID; BODY MASS INDEX; CHILD; COHORT STUDIES; CREATINE; FAMILY; FEMALE; HIPPOCAMPUS; HUMANS; MALE; MEXICO; PROSPECTIVE STUDIES; PROTON MAGNETIC RESONANCE SPECTROSCOPY; TAU PROTEINS; URBAN POPULATION;

EID: 84946040184     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-150415     Document Type: Article

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