Endothelial depletion of murine SRF/MRTF provokes intracerebral hemorrhagic stroke

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 32, 2015, Pages 9914-9919

  Weinl, Christine ^a   Vega, Salvador Castaneda ^b   Riehle, Heidemarie ^a   Stritt, Christine ^a   Calaminus, Carsten ^b   Wolburg, Hartwig ^a   Mauel, Susanne ^c   Breithaupt, Angele ^c   Gruber, Achim D ^c   Wasylyk, Bohdan ^d,e,f,g   Olson, Eric N ^h   Adams, Ralf H ⁱ   Pichler, Bernd J ^b   Nordheim, Alfred ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^c FREIE UNIVERSITÄT BERLIN   (Germany)

^d INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^e CNRS   (France)

^f INSERM   (France)

^g UNIVERSITÉ DE STRASBOURG   (France)

^h UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

ⁱ UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Blood brain barrier; Cerebral microbleeds; Conditional gene knockout; Stroke mouse model; Transcription

Indexed keywords

ALPHA ACTININ; CLAUDIN; COLLAGEN TYPE 4; MYOCARDIN; MYOCARDIN RELATED TRANSCRIPTION FACTOR; PROTEIN; SERUM RESPONSE FACTOR; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN; ZO PROTEIN; CADHERIN; EVANS BLUE; MKL1 PROTEIN, MOUSE; MYOCARDIN-RELATED TRANSCRIPTION FACTOR B, MOUSE; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASEMENT MEMBRANE; BLOOD BRAIN BARRIER; BRAIN BLOOD FLOW; BRAIN HEMORRHAGE; BRAIN TISSUE; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; FEMALE; GENE TARGETING; IN VIVO STUDY; MALE; MEMBRANE STRUCTURE; MICROVASCULATURE; MOUSE; MURINAE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTEIN DEPLETION; TIGHT JUNCTION; TRANSCRIPTION REGULATION; ANIMAL; ASTROCYTE; BRAIN; COMPLICATION; CONTRAST MEDIUM EXTRAVASATION; EXPLORATORY BEHAVIOR; GENE DELETION; GENETICS; KNOCKOUT MOUSE; METABOLISM; MOTOR ACTIVITY; NEWBORN; PATHOLOGY; PATHOPHYSIOLOGY; PERMEABILITY; STROKE; TIME; VASCULARIZATION;

MURINAE; MUS;

ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; BASEMENT MEMBRANE; BLOOD-BRAIN BARRIER; BRAIN; CADHERINS; CEREBRAL HEMORRHAGE; COLLAGEN TYPE IV; DOWN-REGULATION; ENDOTHELIAL CELLS; EVANS BLUE; EXPLORATORY BEHAVIOR; EXTRAVASATION OF DIAGNOSTIC AND THERAPEUTIC MATERIALS; GENE DELETION; MAGNETIC RESONANCE IMAGING; MICE, KNOCKOUT; MICROVESSELS; MOTOR ACTIVITY; PERMEABILITY; SERUM RESPONSE FACTOR; STROKE; TIGHT JUNCTIONS; TIME FACTORS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 84938934782     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1509047112     Document Type: Article

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